COX2 Antibody MA5-14568 from Thermo Fisher Scientific

Product Specs
ItemCOX2 Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberMA5-14568
ApplicationsImmunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate/TagUnconjugated
HostRabbit
Quantity500 µL
FormatPBS with 1% BSA and 0.1% sodium azide; pH 7.2
IsotypeIgG
TargetCOX2
CloneSP21
ReactivityHuman
ClonalityMonoclonal
ImmunogenA synthetic peptide from C-terminus of rat cox2
Storage Temperature4° C
NCBI Full Gene Nameprostaglandin-endoperoxide synthase 2
NCBI Gene AliasesCOX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2
Antibody TypePrimary
Concentration0.006 mg/mL
Storage-20°C, Avoid Freeze/Thaw Cycles
PurityProtein A

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Thermo Fisher Scientific

81 Wyman Street

Waltham, MA 02451

United States

Phone: 800-678-5599
Fax: 800-331-2286

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Website: www.thermofisher.com

(1) Multi-Omics Profiling of High-Grade Serous Ovarian Cancer Reveals an Inflammation-Related Lipid Metabolism Subtype Associated With Platinum ResistanceAdv Sci (Weinh)July 17, 2026Yuxi Zhao, Junyi Li, Bo Zheng, Wanshan Liu, Yaru Wang, Shufeng Wang, Ying Cui, Huiqin Guo, Hongxia Wang, Ting Xiao, et al.5741, Cell Signaling, USA), anti‐CD163 (Cat No. 68218‐1‐Ig, Proteintech, USA), and anti‐COX‐2 (Cat No. MA5‐14568, Invitrogen, USA) antibodies. Two independent pathologists evaluated the IHC slides while being blinded

(2) STAT1 transcriptionally activates CXCL13 to promote cell inflammation and proliferation and inhibit cell apoptosis in rheumatoid arthritis fibroblast-like synoviocytesJournal of Orthopaedic Surgery and ResearchFebruary 3, 2026Mei Wang, Xia Wang, Yujie Wang, Na Zhao, Liguo Yin, Naiwen HuThermo Fisher), interleukin-8 (IL-8, 1:1000, PA5-79113, Thermo Fisher), cyclooxygenase-2 (COX-2, 1:1000, MA5-14568, Thermo Fisher), and GAPDH (1:50000, MA5-35235, Thermo Fisher). Subsequent incubation for one hour utilized

(3) Cyclooxygenase-2 and von Willebrand factor-an immunohistochemical study of the equine foot with and without laminitis, post-mortem perfused with paraffin oilFront Vet SciDecember 15, 2025Bianca A. Underberg, Elke Van der Vekens, Barbara Drews, Sabine Kaessmeyerantibody, rabbit anti-COX-2 (Thermo Fisher Scientific, Massachusetts, United States, article number MA5-14568) were used (Table 2). 2.6.2 IHC staining protocols An IHC staining protocol for anti-COX2 was established

(4) An Ex Vivo Model of Intervertebral Disc Degeneration for Assessing Retention of Injectable Cell‐Based GraftsJOR SPINEDecember 1, 2025Raphael Schmid, Janhavi Apte, Elias Schulze, Andrej Sirek, Günther Schäfer, Jessica Schäper, Francesco Santini, Simona Negoias, Andrea Barbero, Ivan Martin, et al.bovine cells), MMP13 (1:100, 18 165‐1‐AP, Proteintech; immunoreactive in human cells), COX2 (1:100, MA5‐14568, Thermofisher; immunoreactive in human and bovine cells). Matching secondary antibodies Alexa Fluor

(5) Decoding the amniotic membrane transcriptome during equine ascending placentitisSci RepAugust 21, 2025Sophia P. Marchio, Hossam El-Sheikh Ali, Matthew A. Scott, Claudia Barbosa Fernandes, Kirsten E. Scoggin, Mats Troedsson, Yatta Boakarirabbit anti-human TLR4 (1:200; #PA5-23284, ThermoFisher Scientific) or rabbit anti-human PTGS2 (1:100; MA5-14568, ThermoFisher Scientific). Paraffin sections were processed by the Leica BOND-MAX system (Leica Microsystems,

(6) Alleviating the IL-1β-stimulated extracellular matrix degradation in osteoarthritis, and chondrocyte inflammation by Morinda officinalis polysaccharide via the SIRT6/NF-κB pathwayBiomolecules and BiomedicineJuly 1, 2025Dongfang Zhao, Shuqin Xing, Jiao Qi, Zhiqiang Wei, Jianghai Huang, Jigao Sun, Xinzhu Wen, Yafei Wanginducible nitric oxide synthase (iNOS, 1:1000; PA1-036, Invitrogen), cyclooxygenase-2 (COX-2, 1:1000; MA5-14568, Invitrogen), collagen type II ALPHA 1 chain (COL2A1, 1:1000; PA5-99159, Invitrogen), matrix metalloproteinase

(7) Embryo-derived trypsin-induced calcium entry is inhibited by endometrial infertility factor, LEFTY2Frontiers in cell and developmental biologyJanuary 1, 2025Yang Z, Yan J, Kull S, Alauddin M, Brucker SY, Henes M, Lang F, Salker MS.(1:500, sc-365845, Santa Cruz, Germany), CACNA1C (1:200, ACC-013, Alomone Labs, Israel), COX2 (1:200, MA5-14568, ThermoFisher, Germany), GAPDH (1:1,000, #2118L, Cell Signaling, Germany) was used for loading control.

(8) ZnR/GPR39 regulates hepatic insulin signaling, tunes liver bioenergetics and ROS production, and mitigates liver fibrosis and injuryRedox biologyDecember 1, 2024Shendge AK, Sekler I, Hershfinkel M.anti-p-P38 (cst-9211), anti-t-P38 (cst-9212), anti-insulin receptor (ab-137747), Cox-2 (Invitrogen-MA5-14568), anti-β-actin (mp-69100) antibodies. After overnight incubation, the membranes were washed with 1x

(9) Histological and Molecular Biological Changes in Canine Skin Following Acute Radiation Therapy-Induced Skin InjuryAnimals : an open access journal from MDPIAugust 29, 2024Lee SY, Hwang G, Choi M, Jo CH, Oh SJ, Jin YB, Lee WJ, Rho GJ, Lee HC, Lee SL, et al.washed twice in PBS. The slides were incubated with primary antibodies, such as COX–2 (1:200, cat. no. Ma5-14568, Invitrogen, Carlsbad, CA, USA) and Cytokeratin 10 (1:100, cat. no. sc-70907, Santa Cruz, CA, USA) at

(10) High molecular weight hyaluronic acid drastically reduces chemotherapy-induced mucositis and apoptotic cell deathCell death & diseaseJuly 21, 2023Mohammed AI, Celentano A, Paolini R, Low JT, Silke J, O' Reilly LA, McCullough M, Cirillo N.to standard protocols. Slides were then prepared for IHC with anti-COX-2 (SP21, 1/50, Thermofisher# MA5-14568.) or anti-cleaved -caspase-3 (CC3) (#9661 (Ap175), 1/300, Cell Signalling Technology; MA, USA) polyclonal

(11) CircSLCO3A1 depletion ameliorates lipopolysaccharide-induced inflammation and apoptosis of human pulmonary alveolar epithelial cells through the miR-424-5p/HMGB3 pathwayMolecular & cellular toxicologyMay 25, 2023Li Y, Zhang C, Zhao Z.(anti-iNOS; Cat#MA5-17139; 1:1000; Thermo Fisher, Waltham, MA, USA), anti-cyclooxygenase-2 (anti-COX2; Cat#MA5-14568; 1:1000; Thermo Fisher), anti-p-p65 (Cat#AF2006; 1:2000; Affinity, Nanjing, China), anti-p65 (Cat#AF5006;

(12) Transcorneal but not transpalpebral electrical stimulation disrupts mucin homeostasis of the ocular surfaceBMC ophthalmologyDecember 15, 2022Yang M, Lennikov A, Chang K, Ashok A, Lee C, Cho KS, Utheim TP, Dartt DA, Chen DF.incubated with primary antibodies to MUC4 (1:100; AB1793, Abcam, Cambridge, MA, USA) and ZO-1 (1:100; MA5-14568, Thermo Fisher Scientific, Waltham, MA, USA) overnight at 4 °C and washed with PBST. After PBST washing,

(13) Direct modulation of microglial function by electrical fieldFrontiers in cell and developmental biologyJanuary 1, 2022Lennikov A, Yang M, Chang K, Pan L, Saddala MS, Lee C, Ashok A, Cho KS, Utheim TP, Chen DF.incubated with primary antibodies TNFa (1:100; AB1793, Abcam, Cambridge, MA, Unites States), COX-2 (1:100; MA5-14568, Thermo Fisher Scientific, Waltham, MA, Unites States), β-Tubulin (1:200; MA5-16308, Thermo Fisher Scientific,

(14) MicroRNA-183-5p protects human derived cell line SH-SY5Y cells from mepivacaine-induced injuryBioengineeredDecember 1, 2021Zhou Q, Zhang L.Abcam, 1: 1000), anti-Bax (ab32503, Abcam, 1: 1000), anti-PDCD4 (ab211501, Abcam, 1: 1000), anti-COX-2 (MA5-14568, Invitrogen, 1:1000), anti-iNOS (PA1-032, Invitrogen, 1:500) and anti-β-actin (ab8226, Abcam, 1: 2000).

(15) The Prostaglandin Pathway is Activated in Patients who Fail Medical Therapy for Benign Prostatic Hyperplasia (BPH) with Lower Urinary Tract Symptoms (LUTS)The ProstateSeptember 1, 2021RenJie Jin, Douglas W. Strand, Connor M. Forbes, Thomas Case, Justin M. M. Cates, Qi Liu, Marisol Ramirezâ€Solano, Ginger L. Milne, Stephanie Sanchez, Zunyi Y. Wang, et al.protocol. Primary antibodies used for IHC were COX1 (Abcam, ab109025, 1/500), and COX2 (Invitrogen, MA5–14568, 1/500 ThermoFisher Scientific). 2.5 In vitro Smooth Muscle Assay Male C57/Bl6 mice and Sprague Dawley

(16) Protein Digests and Pure Peptides from Chia Seed Prevented Adipogenesis and Inflammation by Inhibiting PPARγ and NF-κB Pathways in 3T3L-1 AdipocytesNutrientsJanuary 8, 2021Grancieri M, Martino HSD, Gonzalez de Mejia E.RIPA Lysis Buffer System were obtained from Santa Cruz Biotechnology (Santa Cruz, CA, USA). Primary antibodies COX-2 (MA5-14568), glyceraldehyde 3-phosphate dehydrogenase (GAPDH) (MA5-15738), 2′,7′-dichlorodihydrofluorescein diacetate

(17) Endotoxin-induced changes in expression of cyclooxygenase isoforms in the lamellar tissue of extracorporeally haemoperfused equine limbsAnatomia, histologia, embryologiaSeptember 1, 2020Patan-Zugaj B, Egerbacher M, Licka TF.

(18) Discovery of novel L-type voltage-gated calcium channel blockers and application for the prevention of inflammation and angiogenesisJournal of neuroinflammationApril 25, 2020Saddala MS, Lennikov A, Mukwaya A, Yang Y, Hill MA, Lagali N, Huang H.blocked with 5% NGS (Thermo Fisher Scientific) for 1 h at RT. The samples were incubated with COX-2 (MA5-14568; 1:1000; Thermo Fisher Scientific) and p-IκB-α (B-9) (sc-8404; 1:100; Santa Cruz Biotechnology, CA,

(19) The Efficacy of Processing Strategies on the Gastroprotective Potentiality of Chenopodium quinoa SeedsTheScientificWorldJournalJanuary 1, 2020Mariod AA, Salama SM.The stomach tissue sections were then incubated with rabbit monoclonal antibodies COX-2 (catalog # MA5-14568) and iNOS (catalog # PA1-036) (Thermo Fisher Scientiﬁc, Waltham, Massachusetts, USA) and added at dilution

(20) Activities of Ca²⁺-related ion channels during the formation of kidney stones in an infection-induced urolithiasis rat modelAmerican journal of physiology. Renal physiologyNovember 1, 2019Cherng JH, Hsu YJ, Liu CC, Tang SH, Sartika D, Chang SJ, Fan GY, Wu ST, Meng E.abundance was detected by staining with MCP-1 (catalog no. 500-P76, PeproTech), COX-2 (catalog no. MA5-14568, ThermoFisher Scientific), OPN (catalog no. sc-73631, Santa Cruz Biotechnology), and TRPV5 (catalog

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COX2 Antibody

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COX2 Antibody from Thermo Fisher Scientific

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