IRP2 Antibody

Product Specs
ItemIRP2 Antibody - BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $419.00Supplier Page View Company Product Page
Catalog NumberNB100-1798
NCBI Gene AliasesIrp2, IRP2AD, IRE-BP 2, D9Ertd85e, NDCAMA, IRP2, ACO3, IRE-BP2
ImmunogenA synthetic peptide made to an internal portion of the murine IRP2 protein sequence (between residues 100-200). [UniProt Q811J3]
Concentration1.15 mg/ml
Quantity0.1 ml (also 0.025 ml)
HostRabbit
ReactivityHuman,Mouse
TargetIRP2
ApplicationsImmunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Gel Super Shift Assays,Gel Supershift Assay,Immunocytochemistry/ Immunofluorescence
Conjugate/TagUnconjugated
FormatTris-Glycine and 0.15M NaCl
NCBI Full Gene Nameiron responsive element binding protein 2
ClonalityPolyclonal
PurityImmunogen affinity purified
Research AreaHIF Target Genes, Hypoxia, Lipid and Metabolism
IsotypeIgG
Antibody TypePrimary Antibodies
StorageStore at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Sizes Available: 0.1 ml (also 0.025 ml)

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Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) Pathological frataxin deficiency in mice causes tissue-specific alterations in iron homeostasisiScienceFebruary 20, 2026Maria Pazos-Gil, Marta Medina-Carbonero, Arabela Sanz-Alcázar, Marta Portillo-Carrasquer, Luiza Oliveira-Jorge, Gonzalo Hernández, Mayka Sánchez, Fabien Delaspre, Elisa Cabiscol, Joaquim Ros, et al.(ThermoFisher, PA5-113382), PPAT 1:1000 (LifeTechnologies, PA5-27770) and IRP2 1:1000 (Novus Biologicals, NB100-1798). For IRP2, as this antibody cross-reacts with other neighboring bands, specificity was verified in

(2) Identification of nonferritin mitochondrial iron deposits in a mouse model of Friedreich ataxiaProceedings of the National Academy of Sciences of the United States of AmericaJanuary 1, 0001"Whitnall M, Suryo Rahmanto Y, Huang ML, Saletta F, Lok HC, Gutiérrez L, Lázaro FJ, Fleming AJ, St Pierre TG, Mikhael MR, et al."

(3) Alterations in renal iron metabolism caused by a copper/zinc-superoxide dismutase deficiencyFree radical researchJanuary 1, 0001"Yoshihara D, Fujiwara N, Kato S, Sakiyama H, Eguchi H, Suzuki K."

(4) Artesunate induces ER-derived-ROS-mediated cell death by disrupting labile iron pool and iron redistribution in hepatocellular carcinoma cellsAmerican journal of cancer researchJanuary 1, 0001"Jiang Z, Wang Z, Chen L, Zhang C, Liao F, Wang Y, Wang Y, Luo P, Luo M, Shi C."

(5) Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in miceNature medicineJanuary 1, 0001"Cloonan SM, Glass K, Laucho-Contreras ME, Bhashyam AR, Cervo M, Pabón MA, Konrad C, Polverino F, Siempos II, Perez E, et al."to the manufacturers instructions. Supershift assays were carried out using 2.5 μg of anti-Irp2 IgG (NB100-1798, Novus Biologicals). Immunohistochemistry and immunofluorescence staining We prepared and stained

(6) Ferroptosis-dependent extracellular vesicles from macrophage contribute to asbestos-induced mesothelial carcinogenesis through loading ferritinRedox biologyJanuary 1, 0001"Ito F, Kato K, Yanatori I, Murohara T, Toyokuni S."anti-FtL (abcam, ab69090), anti-FtH (SantaCruz, sc-H53), anti-IRP1 (CST, #20272), anti-IRP2 (Novus, NB100-1798), Cell Cycle Regulation Antibody Sampler Kit (CST, #9932), anti-mouse IgG Alexa488 (Thermo Fischer Scientific,

(7) Ferroptosis resistance determines high susceptibility of murine A/J strain to iron-induced renal carcinogenesisCancer scienceJanuary 1, 0001"Cheng Z, Akatsuka S, Li GH, Mori K, Takahashi T, Toyokuni S."ABclonal), rabbit monoclonal anti–IRP1 antibody (ab126595, Abcam), rabbit polyclonal anti–IRP2 antibody (NB100‐1798, Novus), rabbit polyclonal anti–FTH1 antibody (3998, CST), rabbit polyclonal anti–ferritin light chain

(8) Neurons lacking iron regulatory protein-2 are highly resistant to the toxicity of hemoglobinNeurobiology of diseaseJanuary 1, 0001"Regan RF, Chen M, Li Z, Zhang X, Benvenisti-Zarom L, Chen-Roetling J."State University, 1:10,000; 3) rabbit antiIRP2, Novus Biologicals, Littleton, CO, USA, Product No. NB100-1798, 1:500; 4) rabbit antiHO-1, Assay Designs, Ann Arbor, MI, Product No. SPA-895, 1:5000; 5) rabbit anti-horse spleen

(9) Fam96a is essential for the host control of Toxoplasma gondii infection by fine-tuning macrophage polarization via an iron-dependent mechanismPLoS neglected tropical diseasesJanuary 1, 0001"Liu Z, Wang H, Zhang Z, Ma Y, Jing Q, Zhang S, Han J, Chen J, Xiang Y, Kou Y, et al."no., 9167) were all purchased from Cell Signaling Technology (Danvers, MA, USA); anti-IRP2 (cat no., NB100-1798), and anti-FPN (cat no., NBP1-21502) were from Novus Biologicals (Centennial, CO, USA); anti-iNOS (cat

(10) Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosisRedox biologyJanuary 1, 0001"Masaldan S, Clatworthy SAS, Gamell C, Meggyesy PM, Rigopoulos AT, Haupt S, Haupt Y, Denoyer D, Adlard PA, Bush AI, et al."were purchased from Abcam. Anti-TfR1 (H68.4, 1:1000) was purchased from Invitrogen. Anti-IRP2 (Cat#NB100-1798, 1:1000) was purchased from Novus Biologicals. Anti-DMT1 (Cat#NRAMP21-P, 1:1000) was purchased from

(11) Regulation of iron metabolism in Hamp (-/-) mice in response to iron-deficient dietEuropean journal of nutritionJanuary 1, 0001"Masaratana P, Patel N, Latunde-Dada GO, Vaulont S, Simpson RJ, McKie AT."

(12) Activation of lysosomal iron triggers ferroptosis in cancerNatureJanuary 1, 0001"Cañeque T, Baron L, Müller S, Carmona A, Colombeau L, Versini A, Solier S, Gaillet C, Sindikubwabo F, Sampaio JL, et al."in-house); 4-HNE (Abcam, ab48506, clone HNEJ-2, lot 1062274-2, FI, 1:200, Hu); IRP2 (Novus Biologicals, NB100-1798, lot D-4, WB, 1:1,000, Hu); Lamin A/C (Cell Signaling, 2032S, lot 6, WB, 1:1,000, Hu); LAMP1 (Cell Signaling,

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IRP2 Antibody

IRP2 Antibody

IRP2 Antibody

IRP2 Antibody

IRP2 Antibody - BSA Free from Novus Biologicals, a Bio-Techne Brand

Specifications/Features

Novus Biologicals, a Bio-Techne Brand

Citations (12)

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IRP2 Antibody - BSA Free from Novus Biologicals, a Bio-Techne Brand

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