FMRP (D14F4) Rabbit mAb 7104S from Cell Signaling Technology

Product Specs
ItemFMRP (D14F4) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number7104S
Quantity100 µl
ApplicationsW, IF-IC
ReactivityH, M, R, Mk
TargetFMRP
HostRabbit
NCBI Gene AliasesFMRP, FRAXA, POF, POF1
ClonalityMonoclonal
NCBI Full Gene Namefragile X messenger ribonucleoprotein 1
Research AreaTranslational Control
IsotypeIgG
CloneD14F4
Molecular Weight80

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Visualizing PINK1 Activity Dynamics in Single Cells with a Phase Separation-Based Kinase Activity ReporterACS SensorsFebruary 27, 2026Katie G. Vineall, Alexia Andrikopoulos, Michael J. Sun, Anna Yan, Ethan R. Hartanto, Danielle L. SchmittTriton X-100 (cat X) and 5% BSA per well. FMRP (D14F4) rabbit mAb (Cell Signaling Technology, Cat #7104) was added to coverslips at 1:200 overnight at 4°C. The next day, cells were incubated with HRP-Goat-anti-Rabbit

(2) Visualizing PINK1 Activity Dynamics in Single Cells with a Phase Separation-Based Kinase Activity ReporterbioRxivOctober 22, 2025Katie G. Vineall, Alexia Andrikopoulos, Michael J. Sun, Anna Yan, Ethan R. Hartanto, Danielle L. SchmittTriton X-100 (cat X) and 5% BSA per well. FMRP (D14F4) rabbit mAb (Cell Signaling Technology, Cat #7104) was added to coverslips at 1:200 overnight at 4°C. The next day, cells were incubated with HRP-Goat-anti-Rabbit

(3) Deep functional measurements of Fragile X syndrome human neurons reveal multiparametric electrophysiological disease phenotypeCommunications biologyNovember 6, 2024Fink JJ, Delaney-Busch N, Dawes R, Nanou E, Folts C, Harikrishnan K, Hempel C, Upadhyay H, Nguyen T, Shroff H, et al.pan-neuronal marker MAP2 antibody (Novus Biological; NB300-213, 1:3000) and FMRP antibody (Cell Signaling, 7104S, 1:100). After five washes with 0.1% Tween-PBS, cells were treated with secondary (Alexa®-conjugated)

(4) Behavioral, neurotransmitter and transcriptomic analyses in male and female Fmr1 KO miceFrontiers in Behavioral NeuroscienceSeptember 6, 2024Deirdre M. McCarthy, Cynthia Vied, Mia X. Trupiano, Angeli J. Canekeratne, Yuan Wang, Christopher Schatschneider, Pradeep G. BhideThe membranes were incubated with rabbit anti-FMRP monoclonal antibody (Cell Signaling Technology, #7104; 1:1,000; 80 kDa), and mouse β-tubulin antibody (loading control; Sigma Aldrich, #T8328; 1:5,000; 50

(5) mGluR7 allosteric modulator AMN082 corrects protein synthesis and pathological phenotypes in FXSEMBO Molecular MedicineFebruary 19, 2024Vipendra Kumar, Kwan Young Lee, Anirudh Acharya, Matthew S Babik, Catherine A Christian-Hinman, Justin S Rhodes, Nien-Pei TsaiAbcam: anti-phospho-eIF4E (#2069, 1:1000 dilution); from Cell Signaling Technology: rabbit anti-FMRP (#7104, 1:2500 dilution); rabbit anti-N-cadherin (#13116, 1:2500 dilution); rabbit anti-ERK1/2 (#4695, 1:5000

(6) Blockade of Type 2A Protein Phosphatase Signaling Attenuates Complement C1q-Mediated Microglial Phagocytosis of Glutamatergic Synapses Induced by Amyloid FibrilsMolecular NeurobiologyMarch 1, 2023Jiang Wu, Jijun Xu, Mohamed Naguib, Bihua Bieanti-PP2A antibody (1:1000; Cell Signaling Technology, #2259), anti-FMRP antibody (1:1000; Cell Signaling, 7104), monoclonal anti-pFMRP antibody (1:1000; Thermo Scientific, PA5-35,389), and monoclonal anti-β-actin

(7) Cellular distribution of the Fragile X mental retardation protein in the inner ear: a developmental and comparative study in the mouse, rat, gerbil, and chickenThe Journal of comparative neurologyJanuary 1, 2023Wang X, Fan Q, Yu X, Wang Y.of human FMRP protein,"Rabbit, monoclonal, 1:100 (ICC); 1:1000 (WB)","Cell Signaling Technology Cat# 7104, RRID: AB_10950502" Ab17722,within human FMRP aa 550 to the C-terminus,"Rabbit, polyclonal, 1:1000

(8) Raloxifene prevents stress granule dissolution, impairs translational control and promotes cell death during hypoxia in glioblastoma cellsCell death & diseaseNovember 17, 2020Attwood KM, Robichaud A, Westhaver LP, Castle EL, Brandman DM, Balgi AD, Roberge M, Colp P, Croul S, Kim I, et al.diluted 1:200), G3BP2 (Sigma-Aldrich, HPA018304; diluted 1:1500), or FMRP (Cell Signaling Technology, 7104; diluted 1:400) in 1% BSA. Subsequently, cells were incubated with Alexa Fluor 488-chicken anti-mouse

(9) UV damage induces G3BP1-dependent stress granule formation that is not driven by mTOR inhibition-mediated translation arrestJournal of cell scienceOctober 28, 2020Ying S, Khaperskyy DA.Labs., A301-761A); eIF4G (1:200; rabbit, Cell Signaling, #2498); FMRP (1:200; rabbit, Cell Signaling, #7104); G3BP1 (1:400; mouse, BD Transduction, 611126); G3BP2 (1:1000; rabbit, Millipore Sigma, HPA018304);

(10) EphA4 Is Required for Neural Circuits Controlling Skilled ReachingThe Journal of NeuroscienceSeptember 9, 2020Juan Jiang, Klas Kullander, Bror AlstermarkEphA4 knock-out mice, abnormal patterns of CST 7092 • J. Neurosci., September 9, 2020 • 40(37):7091–7104 projections have been observed in the cervical spinal cord (Dottori et al., 1998; Coonan et al., 2001),

(11) FMRP(1-297)-tat restores ion channel and synaptic function in a model of Fragile X syndromeNature communicationsJune 2, 2020Zhan X, Asmara H, Cheng N, Sahu G, Sanchez E, Zhang FX, Zamponi GW, Rho JM, Turner RW.working solution: rabbit monoclonal anti-FMRP C-terminal antibody (1:200, Cell Signaling Technology, 7104S), mouse monoclonal anti-HA (1:300, Abcam, ab130275), and chicken polyclonal anti-MAP2 (1:500, Abcam,

(12) Activation of mGluR1 Mediates C1q-Dependent Microglial Phagocytosis of Glutamatergic Synapses in Alzheimer's Rodent ModelsMolecular neurobiologyAugust 1, 2019Bie B, Wu J, Foss JF, Naguib M.monoclonal anti-C1q antibody (1:1000; Abcam, ab71940), anti-FMRP antibody (1:1000; Cell Signaling, 7104), monoclonal anti-pFMRP antibody (1:1000; Thermo Scientific, PA5–35389), and monoclonal anti-β-actin antibody

(13) Neuroligin 1, 2, and 3 Regulation at the Synapse: FMRP-Dependent Translation and Activity-Induced Proteolytic CleavageMolecular neurobiologyApril 1, 2019Chmielewska JJ, Kuzniewska B, Milek J, Urbanska K, Dziembowska M.incubated with anti-fluorescein-POD (1:200 in TNB, Roche) and rabbit anti-FMRP antibodies (1:200 in TNB, #7104S, Cell Signaling) in humidified chamber overnight in 4 °C, washed with PBST, and incubated with Alexa

(14) Induction of apoptosis in ovarian cancer cells by miR-493-3p directly targeting AKT2, STK38L, HMGA2, ETS1 and E2F5Cellular and molecular life sciences : CMLSFebruary 1, 2019Kleemann M, Schneider H, Unger K, Bereuther J, Fischer S, Sander P, Marion Schneider E, Fischer-Posovszky P, Riedel CU, Handrick R, et al.Bcl-XL (1:1000; cs#2764T), MCL1 (1:1000; 623 cs#94296), RAF1 (1:1000; cs#53745), FMR1P (1:1000; cs#7104), FOXM1 (1:1000; 624 cs#5436), HMGA2 (1:1000; cs#5269), MAPK1 (1:1000; cs#9102S) and STAT3 625 (1:1000;

(15) Loss of the fragile X mental retardation protein causes aberrant differentiation in human neural progenitor cellsScientific reportsAugust 2, 2018Sunamura N, Iwashita S, Enomoto K, Kadoshima T, Isono F.directed against GFAP (1/2500, #130300, Thermo Fisher Scientific, 1/1000, #53554, abcam), FMRP (1/1000, #7104, Cell Signaling Technology, Beverly, MA, USA), GAPDH (1/1000, #M171-7, MBL), mTOR (1/1000, #2983 P,

(16) Loss of protein phosphatase 6 in mouse keratinocytes enhances K-ras ^G12D -driven tumor promotionCancer ScienceJuly 1, 2018Koreyuki Kurosawa et al.

(17) ATX‑LPA axis facilitates estrogen‑induced endometrial cancer cell proliferation via MAPK/ERK signaling pathwayMolecular medicine reportsMarch 1, 2018Zhang G, Cheng Y, Zhang Q, Li X, Zhou J, Wang J, Wei L.

(18) Hypervariable Domain of Eastern Equine Encephalitis Virus nsP3 Redundantly Utilizes Multiple Cellular Proteins for Replication Complex AssemblyJournal of VirologyJuly 15, 2017Ilya Frolov, Dal Young Kim, Maryna Akhrymuk, James A. Mobley, Elena I. Frolovaantibodies (catalog number 7098; Cell Signaling), and anti-FMR1 rabbit monoclonal antibodies (catalog number 7104; Cell Signaling). Cell nuclei were stained with Hoechst dye. Three-dimensional images were acquired

(19) miR-132 Regulates Dendritic Spine Structure by Direct Targeting of Matrix Metalloproteinase 9 mRNAMolecular NeurobiologySeptember 1, 2016Magdalena Jasińska, Jacek Miłek, Iwona A. Cymerman, Szymon Łęski, Leszek Kaczmarek, Magdalena Dziembowskanormalized to beta-actin. To test the immunoprecipitation efficiency, Western blot with anti-FMRP antibody (#7104; Cell Signaling) was performed. Spine Clustering and Spine Parameters Estimation Images of fixed,

(20) New World and Old World Alphaviruses Have Evolved to Exploit Different Components of Stress Granules, FXR and G3BP Proteins, for Assembly of Viral Replication ComplexesPLOS PathogensAugust 10, 2016Dal Young Kim, Josephine M. Reynaud, Aliaksandra Rasalouskaya, Ivan Akhrymuk, James A. Mobley, Ilya Frolov, Elena I. Frolovaanti-FXR2 rabbit monoclonal antibodies (#7098, Cell Signaling), anti-FMR1 rabbit monoclonal antibodies (#7104, Cell Signaling), anti-CHIKV nsP3 mouse monoclonal antibodies (provided by UAB Epitope Recognition &

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FMRP (D14F4) Rabbit mAb

FMRP (D14F4) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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FMRP (D14F4) Rabbit mAb from Cell Signaling Technology

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