UHRF1 (H-8) Antibody sc-373750 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemUHRF1 (H-8) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-373750
Antibody TypePrimary Antibodies
Hostmouse
Conjugate/TagUnconjugated
Reactivitymouse, rat, human
ClonalityMonoclonal
Quantity200 µg/ml
CloneH-8
ApplicationsWB, IP, IF, IHC(P), ELISA
TargetUHRF1
NCBI Full Gene Nameubiquitin like with PHD and ring finger domains 1, ubiquitin-like, containing PHD and RING finger domains, 1
NCBI Gene AliaseshUHRF1, ICBP90, TDRD22, RNF106, Np95, huNp95, hNP95
FormatPurified
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Uhrf1 loss disrupts Ctcf-associated chromatin organization during early mouse embryogenesisbioRxivJuly 20, 2026Agata Kurowski, Bohan Zhu, Yifei Sun, Paul Sargunas, Nimisha Jain, Ashley Chan, Lahouaria Hadri, Yi Shi, Martin J. Walsh, Sai Ma(GE Healthcare Life sciences), and immunoblotted with the indicated with Uhrf1 antibody (Santa Cruz, sc-373750) followed by ECL detection (Thermo Scientific). Immunofluorescence staining Immunostaining was performed

(2) RAC1 regulates Sonic Hedgehog-medulloblastoma growth via GLI-mediated transcriptionNeuro-OncologyJune 1, 2026Nitish Jangde, Mi-Hye Lee, Luz Ruiz, Isabelle Egan, Anna M Jermakowicz, Rishika Chowdary, Jonathan Chu, Daniel T Wynn, Erik Goka, Marc Lippman, et al.Sigma) as described by the manufacturer. The following antibodies were used for PLA: UHRF1 (catalog no. sc-373750, Santa Cruz Biotechnology, RRID: AB_10947236), DNMT1 (catalog no. 5032, Cell Signaling Technology, RRID:

(3) Selective cellular localization of UHRF1 safeguards mammalian zygotic genome activation and early embryonic developmentCell DiscovMay 26, 2026Rui Yan, Xin Cheng, Xin Long, Yating Zhu, Qiancheng Zhang, Fengyuan Sun, Fan Zhang, Mengyue Wang, Ruifeng Zhang, Tianzi Guo, et al.polyclonal antibody (homemade); anti-DNMT1 (Cell Signaling, Cat# 5032S); anti-UHRF1 (Santa Cruz, Cat# sc-373750); anti-UHRF1 (ABclonal, Cat# A2343); anti-DPPA3 (Abclonal, Cat# A20176); anti-HA (ABclonal, Cat# AE008);

(4) UHRF1 drives subtype-independent aggressiveness and immune evasion in small cell lung cancer through PRC2 interactionsiScienceApril 17, 2026Yijun Gu, Jamie-Jean De La Torre, Yasamin Fazeli, J. Mateo Valenzuela, Frederick Guzman, Roberto Tinoco, Claudia A. Benaventeor RESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies ,, UHRF1,Santa Cruz Biotechnology,sc-373750 ß-Actin,Sigma-Aldrich,A1978 Synaptophysin (SYP),Cell Signaling Technology,36406 NCAM1,Cell Signaling Technology

(5) NLRP14 modulates the activity of E3 ubiquitin ligases during the oocyte-to-embryo transitionNature CommunicationsApril 8, 2026Sibei Liu, Qianqian Qi, Pengliang Chi, Haizhan Jiao, Li Yan, Yuechao Lu, Rongrong Zhang, Jinhong Li, Sicheng Ju, Zhuo Han, et al.peroxidase (HRP) (Abclonal, AC028), mouse anti-UHRF1 monoclonal antibody (Santa Cruz Biotechnology, sc-373750), rabbit anti-NLRP14 polyclonal antibody (a gift from Professor Zhonghan Li at Sichuan University),

(6) A simple, efficient, and scalable method to generate oocyte-like cells in vitroLife Science AllianceFebruary 1, 2026Ami Banno, Kana Mizuno, Mizuki Sakamoto, Sota Komatsubara, Kenjiro Shirane, Katsuhiko Hayashi, Nobuhiko Hamazaki, Koshi Imami, Shigenobu Yonemura, Takashi Ishiuchiincubated with primary antibodies overnight at 4°C or for 1 h at RT. The antibodies used are anti-UHRF1 (sc-373750, 1:200; Santa Cruz Biotechnology), anti-MVH (ab27591, 1:200; Abcam), anti-FOXO3 (#2497, 1:400; CST),

(7) A Hybrid compound H93 treats prostate cancer by directly binding UHRF1 and promoting protein dimerizationCommunications chemistryNovember 18, 2025Fu Y, Jiang L, Xie G, Peng Y, Fu Y, Zhu Q, Liu Y, Zhao G, Liu X, Peng Y, et al.was obtained from Sangon Biotech (Shanghai, China). For immunoblotting assays, mouse anti-UHRF1 (Cat#sc-373750, RRID: AB_10947236, Santa cruz, Dallas, TX, USA), rabbit anti-β-Actin (Cat#3700S, RRID: AB_2242334,

(8) Requirements for establishment and epigenetic stability of mammalian heterochromatinMolecular CellSeptember 18, 2025Antonis Tatarakis, Harleen Saini, Juntao Yu, Wenzhi Feng, Carlos A. Pinzon-Arteaga, Danesh MoazedHPA006735), anti-HA Tag (Thermo Fisher Scientific 2–2.2.14), anti-H3 (Abcam ab1791), anti-UHRF1 (Santa Cruz sc-373750). Total RNA Purification, reverse transcription (RT), and qPCR Total RNA from mESCs or NPCs was isolated

(9) UHRF2 mediates resistance to DNA methylation reprogramming in primordial germ cellsNat CommunAugust 9, 2025Ambre Bender, Marion Morel, Michael Dumas, Muriel Klopfenstein, Naël Osmani, Maxim V. C. Greenberg, Déborah Bourc'his, Norbert B. Ghyselinck, Michael Weberreagent (Amersham, GE Healthcare). The following primary antibodies were used: UHRF1 (H8, Santa Cruz sc-373750, 1:100), UHRF2 (C-10, Santa Cruz sc-398953, 1:100), FLAG (Origen TA50011-100, 1:2000), α-TUBULIN (Sigma Aldrich

(10) OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wideNature Structural & Molecular BiologyJuly 1, 2025Hugo Sepulveda, Xiang Li, Leo J. Arteaga-Vazquez, Isaac F. López-Moyado, Melina Brunelli, Lot Hernández-Espinosa, Xiaojing Yue, J. Carlos Carlos Angel, Caitlin Brown, Zhen Dong, et al.anti-Dnmt3a (Abcam, ab2850; 1:3,000); anti-Dnmt3b (Abcam, ab122932; 1:4,000); anti-Uhrf1 (Santa Cruz, sc-373750; 1:8,000); anti-KAP1 (Abcam, ab10483; 1:8,000); β-Actin (Cell Signaling, 5125; 1:10,000); anti-5hmC

(11) Inhibition of epigenetic regulator UHRF1 attenuates renal fibrosis and retains transcription factor Krüppel-like factor 15 expressionCell Death DiscovJune 9, 2025Yulu Gu, Shiqi Lv, Xinhui Huang, Jialin Wang, Yulin Wang, Han Zhang, Ziyan Shen, Jing Chen, Cheng Zhu, Di Zhang, et al.immunofluorescence staining. Primary antibodies used in this study were anti-UHRF1 (Santa Cruz Biotechnology, sc373750), anti-PDGFRα + β (Abcam, ab32570), and anti-AQP1 (Abcam, ab168387). The nuclei were stained with Hochest

(12) A CRISPR-Cas9 screen reveals genetic determinants of the cellular response to decitabineEMBO ReportsFebruary 10, 2025Pinqi Zhang, Zhuqiang Zhang, Yiyi Wang, Wenlong Du, Xingrui Song, Weiyi Lai, Hailin Wang, Bing Zhu, Jun XiongDNA lentiCRISPRv2,Addgene,#52961 LentiGuide,Addgene,#52963 pLenti-EF1A-PGK-puro,homemade,NA AAVS1-Neo-CAG-Flpe-ERT2,Addgene,#68460 Antibodies,Antibodies,Antibodies DCTD,Santa Cruz,sc-376659 DNMT1,Santa Cruz,sc-20701 DNMT1,ABclonal,A16729 UHRF1,Santa Cruz,sc-373750 KDM1A,ABcam,ab17721 γH2A.X,ABcam,ab22551 γH2A.X,ABcam,ab2893 RPA32,Santa Cruz,sc-56770 ZMYM2,Thermo Scientific

(13) Defining ortholog-specific UHRF1 inhibition by STELLA for cancer therapyNature communicationsJanuary 8, 2025Bai W, Xu J, Gu W, Wang D, Cui Y, Rong W, Du X, Li X, Xia C, Gan Q, et al.rabbit anti-UHRF1 (1:100, Thermo Fisher Scientific, PA5-29884), mouse anti-UHRF1 (1:100, Santa Cruz, sc-373750), rabbit anti-DNMT1 (1:1000, Abcam, ab92314), rabbit anti-DNMT3A (1:100, Sigma-Aldrich, HPA026588),

(14) MARTRE family proteins negatively regulate CCR4-NOT activity to protect poly(A) tail length and promote translation of maternal mRNANat CommunJanuary 2, 2025Jing Yang, Jiachen Bu, Bowen Liu, Yusheng Liu, Zhuqiang Zhang, Ziyi Li, Falong Lu, Bing Zhu, Yingfeng Li12987-1-AP), anti-Zscan4 (Millipore, ab4340), anti-H3 (Proteintech, 17168-1-AP), anti-UHRF1 (Santa Cruz, sc-373750), anti-G3BP1 (Abclonal, A3968), anti-Cytochrome C (Proteintech, 66264-1-Ig), anti-CNOT1 (Abclonal, A5969),

(15) PP2A licenses the FANCD2/FANCI complex for chromosome loadingCell ReportsNovember 12, 2024Di Yang, Fengxiang Bai, David Lopez Martinez, Hannan Xu, Ai Johjima-Murata, Lily Jiaqi Cao, Martin A. Cohndilution (FARF); anti-Flag, 1:1,000 dilution (M5, F4042, Sigma-Aldrich); anti-UHRF1, 1:1,000 dilution (sc-373750, Santa Cruz Biotechnology); anti-α-Tubulin, 1:2,000 dilution (05–829, Merck-Millipore). Whole cell

(16) Identification of differentially expressed tumour-related genes regulated by UHRF1-driven DNA methylationScientific ReportsAugust 7, 2024Qincai Dong, Chunxue Gong, Qian Jiang, Yue Liu, Yong Hu, Di Wang, Hainan Liu, Tong Zheng, Caiwei Song, Tingting Wang, et al.a membrane (Millipore), and then immunoblotted with anti-UHRF1 primary antibodies (Santa Cruz, Cat# SC-373750), anti-DNMT1 primary antibodies (Cell Signaling Technology, Cat# 5032) and anti-β-actin (Santa Cruz,

(17) EZH2 K63-polyubiquitination affecting migration in extranodal natural killer/T-cell lymphomaClinical EpigeneticsNovember 29, 2023Boheng Li, Qidi Zhou, Qin Wan, Xuan Qiao, Shangying Chen, Jianbiao Zhou, Zhijun Wuxiao, Lei Luo, Siok-Bian Ng, Jieping Li, et al.Technology C36B11, 1:1000), Histone H3 (Cell Signaling Technology D1H2, 1:2000), UHRF1 (Santa Cruz sc-373750, 1:1000), TRIP12 (proteintech 25303-1-AP, 1:1000), β-tubulin (Wanleibio WL01931, 1:750), GFP (Santa Cruz

(18) NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte-to-Embryo TransitionAdvanced science (Weinheim, Baden-Wurttemberg, Germany)September 1, 2023Meng TG, Guo JN, Zhu L, Yin Y, Wang F, Han ZM, Lei L, Ma XS, Xue Y, Yue W, et al.anti‐Centromere Protein Antibody (for IF, Antibodies Inc, 15–234), anti‐mUHRF1 (for WB and IF, Santa Cruz sc‐373750 (H‐8), anti‐DNMT1 (for WB, MyBioSource, MBS179160), anti‐Drp1 (for WB, abcam, ab184247), anti‐NCLX (for WB

(19) Downregulation of DNA methylation enhances differentiation of THP-1 cells and induces M1 polarization of differentiated macrophagesScientific reportsAugust 12, 2023Park J, Luo Y, Park JW, Kim SH, Hong YJ, Lim Y, Seo YJ, Bae J, Seo SB.SDS-PAGE, western blotting was performed using the following antibodies. Antibodies against UHRF1 (sc-373750, 1:1000), β-actin (sc-47778, 1:1000) (Santa Cruz Biotechnology, Dallas, TX, USA), GAPDH (CSB-PA00025A0Rb,

(20) A novel sorbicillinoid compound as a potent anti-inflammation agent through inducing NLRP3 protein degradationBritish journal of pharmacologyAugust 1, 2023Wang F, Zhang M, Yuan M, Xia Z, Yang F, Zhang S, Lin T, Luo L, Tang J, Zhang Y.RRID:AB_416684), ubiquitin like with PHD and ring finger domains 1 (UHRF1; Santa Cruz Biotechnology, clone H8, Cat#SC-373750, mouse monoclonal, RRID:AB_10947236), p-mTOR (Cell Signaling Technology, S2448, clone D9C2, Cat#5536,

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UHRF1 (H-8) Antibody

UHRF1 (H-8) Antibody from Santa Cruz Biotechnology, Inc.

Santa Cruz Biotechnology, Inc.

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UHRF1 (H-8) Antibody from Santa Cruz Biotechnology, Inc.

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