Mlkl antibody orb32399 from Biorbyt

Product Specs
ItemMlkl antibody
CompanyBiorbyt
Price $300.00Supplier Page
Catalog Numberorb32399
Quantity100 ug, 200 ug
ApplicationsICC, IF, IHC-P, WB
TargetMlkl
Conjugate/TagUnconjugated
HostRabbit
ClonalityPolyclonal
IsotypeIgG
Format10 mM PBS, 0.02% sodium azide
PurityPolyclonal antibodies are purified by peptide affinity chromatography
Molecular Weight54 kDa
ImmunogenKLH conjugated synthetic peptide derived from human Mlkl. Please contact us for the exact immunogen sequence. The peptide is available as orb374793
Concentration- 100 µg (in 200 µl): 0.5 mg/ml- 200 µg (in 400 µl): 0.5 mg/ml
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
NCBI Full Gene Namemixed lineage kinase domain like pseudokinase, mixed lineage kinase domain-like
NCBI Gene Aliases9130019I15Rik, hMLKL

Specifications/Features

Application Dilutions: WB: 1:200-2000, IHC-P: 1:100-500, IF/ICC: 1:100-500

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Local Office

Biorbyt

68 TW Alexander Drive

Durham, North Carolina 27713

United States

Phone: +1 (415) 906-5211

Company Profile

International Office

Biorbyt

7, Signet Court, Swann Road

Cambridge, Cambridgeshire CB5 8LA

United Kingdom

Phone: +44(0)1223 815 212
+44(0)1223 280 240 (fax)
+44(0)1223 280 240

Email: info@biorbyt.com
support@biorbyt.com
accounts@biorbyt.com

Company Profile

Website: https://www.biorbyt.com/

(1) Nutritional, antioxidant and biological activity characterization of orange peel flour to produce nutraceutical gluten-free muffinsFood & functionAugust 12, 2024Caponio GR, Annunziato A, Vacca M, Difonzo G, Celano G, Minervini F, Ranieri M, Valenti G, Tamma G, De Angelis M.

(2) Luteolin-7-O-β-d-glucuronide Ameliorates Cerebral Ischemic Injury: Involvement of RIP3/MLKL Signaling PathwayMoleculesApril 7, 2024Xing Fan, Fang Lin, Yu Chen, Yuling Dou, Ting Li, Xinxin Jin, Jintao Song, Fang Wangsc-47778, 1:1000), RIP1 (BD Biosciences, 610458, 1:1000), RIP3 (Abcam, ab62344, 1:1000), and MLKL (Biorbyt, orb32399, 1:1000) antibodies. β-actin was used as the internal reference to ensure equal loadings. After washing

(3) CHIP ameliorates cerebral ischemia-reperfusion injury by attenuating necroptosis and inflammationAging (Albany NY)December 15, 2021Dabao Yao et al.Abcam), RIPK1 (1:1000, #SAB3500420, Sigma-Aldrich), RIPK3 (1:1000, #ab62344, Abcam), MLKL (1:2000, #orb32399, Biorbyt), p-RIPK3 (1:1000, #AF7443, Affinity), p-MLKL (1:1000, #AF7420, Affinity), and β-actin (1:5000,

(4) Antidepressant Mechanism of Traditional Chinese Medicine Formula Xiaoyaosan in CUMS-Induced Depressed Mouse Model via RIPK1-RIPK3-MLKL Mediated Necroptosis Based on Network Pharmacology AnalysisFrontiers in PharmacologyNovember 19, 2021Zhi-Yi Yan et al.ab56164, Abcam; phosphorylated MLKL (p-MLKL), 1:1,000 dilution, ab196436, Abcam; MLKL, 1:2000 dilution, orb32399, Biorbyt, Cambridge, UK; β-actin, 1:5,000 dilution, #5125, Cell Signal, Danvers, MA, United States).

(5) BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathologyiScienceSeptember 24, 2021Zhang L, Qian Y, Li J, Zhou X, Xu H, Yan J, Xiang J, Yuan X, Sun B, Sisodia SS, et al.anti-human sAPPα,Immuno-Biological Laboratories,Cat# 11088; RRID:AB_494690 Rabbit anti-MLKL,Biorbyt,Cat# orb32399; RRID:AB_10927389 Rabbit anti-8-OHdG,Bioss,Cat# BS-1278R; RRID:AB_10856120 Goat anti-Iba1,Novus Biologicals,Cat#

(6) Cartilage Trauma Induces Necroptotic Chondrocyte Death and Expulsion of Cellular ContentsInternational Journal of Molecular SciencesJune 12, 2020Josef Stolberg-Stolberg, Meike Sambale, Uwe Hansen, Alexandra Schäfer, Michael Raschke, Jessica Bertrand, Thomas Pap, Joanna SherwoodMA, USA) for 45 min (human samples) at 37 ◦ C. All sections were incubated overnight with anti-MLKL (orb32399, Biorbyt, Cambridge, UK) or anti-RIPK3 antibody (ab56164, Abcam, Cambridge, MA, USA) or IgG (Cell Signaling,

(7) Membrane-bound TNF mediates microtubule-targeting chemotherapeutics-induced cancer cytolysis via juxtacrine inter-cancer-cell death signalingCell death and differentiationMay 1, 2020Zhang J, Yang Y, Zhou S, He X, Cao X, Wu C, Hu H, Qin J, Wei G, Wang H, et al.(SIBCB, China). Antibodies and reagents For immunoblotting, anti-MLKL (mouse specific, Biorbyt, #orb32399; human specific, Abcam, #ab184718), anti-phospho-MLKL (mouse specific, Abcam, #ab196436; human specific,

(8) Modulation of the extrinsic cell death signaling pathway by viral Flip induces acute-death mediated liver failureCell death & diseaseNovember 21, 2019Bittel M, Kremer AE, Stürzl M, Wirtz S, Stolzer I, Neurath MF, Ballon G, Günther C.the manufacturer (Perkin&Elmer). The following antibodies were used: murine MLKL (Biorbyt, Cat.No.: orb32399), GSDMD (abcam, Cat.No.: ab209845), Cytokeratin 19 (abcam, Cat.No.: ab52625), cleaved CASP3 (Cell Signaling,

(9) Cell cycle arrest in mitosis promotes interferon-induced necroptosisCell Death & DifferentiationOctober 1, 2019Tanja Frank, Marcel Tuppi, Manuela Hugle, Volker Dötsch, Sjoerd J. L. van Wijk, Simone FuldaMA, USA), rabbit antihuman MLKL (#14993S, Cell Signaling, Beverly, MA, USA), rabbit anti-murine MLKL (orb32399, Biorbyt), mouse anti-cleaved poly(ADP ribose) polymerase (PARP) (#9546S, Cell Signaling, Beverly, MA,

(10) The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosisOncotargetFebruary 27, 2018Fuchslocher Chico J, Falk-Paulsen M, Luzius A, Saggau C, Ruder B, Bolik J, Schmidt-Arras D, Linkermann A, Becker C, Rosenstiel P, et al.phospho S232-RIPK3 (ab195117, Abcam), RIPK3 (PRS2283, Merck), phospho S345-MLKL (ab196436, Abcam), MLKL (orb32399, Biorbyt, Cambridge, UK), cleaved (active) caspase-3 (#9661, Cell Signaling), Bcl-2 (sc-7382, Santa Cruz

(11) The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitisJournal of Clinical InvestigationOctober 17, 2016Claudia Günther et al.(Whatman). Membranes were probed with the following primary antibodies: murine MLKL (Biorbyt, catalog orb32399); RIPK1 (catalog 3493), Na, K-ATPase (catalog 3010), pSTAT1 (catalog 9167), and STAT1 (catalog 14994)

(12) Limb salvage for streptococcal gangrene of the extremityAmerican journal of surgeryMarch 1, 1998Schurr M, Engelhardt S, Helgerson R.

(13) Micellar electrokinetic capillary chromatography of fungal metabolites. Resolution optimized by experimental designJournal of chromatography. AJanuary 19, 1996Nielsen MS, Nielsen PV, Frisvad JC.

(14) Beneficial effects of oral clodronate in the management of malignant osteolysis and hypercalcaemiaBoneFebruary 1, 1995Aranko K, Hanhijärvi H, Humphreys M, Drake J, Lawton WA.

(15) [Thrombectomy of the infra- and suprarenal cava to prevent pulmonary embolism in the presence of deep venous thrombosis. Personal experience with 11 surgically-treated cases]Minerva chirurgicaSeptember 30, 1991Giorgetti PL, Arpesani A, Bortolani EM, Rignano A, Morbidelli A, Vandone PL, Miani S.

(16) Control of mucus secretion in airwaysRespiration; international review of thoracic diseasesJanuary 1, 1991Wagner U, von Wichert P.

(17) Diet and colorectal cancer with special reference to fiber intakeInternational journal of cancerJuly 15, 1989Heilbrun LK, Nomura A, Hankin JH, Stemmermann GN.

(18) [Life and freedom as a compulsion? Considerations of the relation of the phenomenology of life and analysis of existence]Zeitschrift fur klinische Psychologie, Psychopathologie und PsychotherapieJanuary 1, 1988Kühn R.

(19) Chyluria associated with bronchial carcinomaPostgraduate medical journalMarch 1, 1981Morice AH, Wood JR.

(20) [The effect of changes in heart rate, afterload and contractility of the left ventricle on echocardiographic functional parameters]Verhandlungen der Deutschen Gesellschaft fur Innere MedizinJanuary 1, 1978Most E, Stefan G, Bender F.

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Mlkl antibody

WB analysis of rat heart (lane 1), mouse stomach (lane 2), rat liver (lane 3), rat spleen (lane 4), rat lung (lane 5), human breast cancer (lane 6) using Mlkl antibody (1 ug/ml)

Immunohistochemical staining of paraffin embedded guinea pig lung tissue using Mlkl antibody (2.5 ug/ml)

Mlkl antibody

Mlkl antibody

Mlkl antibody from Biorbyt

Description

Specifications/Features

Biorbyt

Biorbyt

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Mlkl antibody from Biorbyt

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