DARC Antibody NB100-2421 from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemDARC Antibody
CompanyNovus Biologicals, a Bio-Techne Brand
Price $429.00Supplier Page View Company Product Page
Catalog NumberNB100-2421
ImmunogenPeptide with sequence HRAELSPSTENSSQLDFED-C corresponding to N-Terminus according to NP_001116423.1, NP_002027.2
Concentration0.5 mg/ml
HostGoat
ReactivityHuman
Quantity0.1 mg (also 0.025 mg)
FormatTris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
ApplicationsIF/IHC,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Peptide ELISA,Immunocytochemistry/ Immunofluorescence
Conjugate/TagUnconjugated
TargetDARC
ClonalityPolyclonal
PurityImmunogen affinity purified
Molecular Weight36 kDa
Research AreaGPCR, Immunology, Innate Immunity
IsotypeIgG
NCBI Full Gene Nameatypical chemokine receptor 1 (Duffy blood group)
NCBI Gene AliasesDfy, GpFy, GPD, FY, WBCQ1, DARC, CD234, DARC/ACKR1, CCBP1
Antibody TypePrimary Antibodies
StorageStore at -20C. Avoid freeze-thaw cycles

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: This antibody is expected to recognize both reported isoforms (NP_001116423.1; NP_002027.2).

Sizes Available: 0.1 mg (also 0.025 mg)

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Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) Multi-omics analysis of human tendon adhesion reveals that ACKR1-regulated macrophage migration is involved in regenerationBone researchMay 7, 2024Zhang X, Xiao Y, Hu B, Li Y, Zhang S, Tian J, Wang S, Tao Z, Zeng X, Liu NN, et al.Novus, NB600-408; CD31, BioLengd, 303103 RGCC, Bioss, bs-9079R; COL4A1, NOVUS, NBP1-97716; ACKR1, NOVUS, NB100-2421;GJA4, ThermoFisher, 42-4400; CXCL14, Abcam, ab264467; ADAM12, Abcam, ab39155; COL4A1, Novus, NBP1-97716;MYH11,

(2) Chemokine (C-C motif) ligand 2 and coronary artery disease: Tissue expression of functional and atypical receptorsCytokineJanuary 1, 0001"Hernández-Aguilera A, Fibla M, Cabré N, Luciano-Mateo F, Camps J, Fernández-Arroyo S, Martín-Paredero V, Menendez JA, Sirvent JJ, Joven J."

(3) "Expression of DARC, CXCR3 and CCR5 in giant cell arteritis""Rheumatology (Oxford, England)"January 1, 0001"Brühl H, Vielhauer V, Weiss M, Mack M, Schlöndorff D, Segerer S."

(4) Coexpression of atypical chemokine binders (ACBs) in breast cancer predicts better outcomesBreast cancer research and treatmentJanuary 1, 0001"Zeng XH, Ou ZL, Yu KD, Feng LY, Yin WJ, Li J, Shen ZZ, Shao ZM."

(5) Host genotype and tumor phenotype of chemokine decoy receptors integrally affect breast cancer relapseOncotargetJanuary 1, 0001"Yu KD, Wang X, Yang C, Zeng XH, Shao ZM."sections were incubated overnight in a 1:500 dilution of goat anti-human DARC polyclonal antibody (NB100-2421, Novus Biologicals, Inc., USA) and 1:250 dilution of goat anti-human D6 polyclonal antibody (PA1-21614,

(6) Distinct Transcript Isoforms of the Atypical Chemokine Receptor 1 (ACKR1)/Duffy Antigen Receptor for Chemokines (DARC) Gene Are Expressed in Lymphoblasts and Altered Isoform Levels Are Associated with Genetic Ancestry and the Duffy-Null AllelePloS oneJanuary 1, 0001"Davis MB, Walens A, Hire R, Mumin K, Brown AM, Ford D, Howerth EW, Monteil M."paraffin embedded and sections stained for DARC/ACKR1 using a goat anti-DARC antibody (Novus biologicals: NB100-2421) and detection with biotinylated anti-goat (Biocare), alkaline phosphatase streptavidin (Biogenex),

(7) Single Cell Transcriptomics of Fibrotic Lungs Unveils Aging-associated Alterations in Endothelial and Epithelial Cell RegenerationbioRxiv : the preprint server for biologyJanuary 1, 0001"Raslan AA, Pham TX, Lee J, Hong J, Schmottlach J, Nicolas K, Dinc T, Bujor AM, Caporarello N, Thiriot A, et al."

(8) Novel Blood Vascular Endothelial Subtype-Specific Markers in Human Skin Unearthed by Single-Cell Transcriptomic ProfilingCellsJanuary 1, 0001"He Y, Tacconi C, Dieterich LC, Kim J, Restivo G, Gousopoulos E, Lindenblatt N, Levesque MP, Claassen M, Detmar M."UK), goat anti-human ERG (1:50, NB100-2472, Novus, Centennial, CO, USA), goat anti-human ACKR1 (1:200, NB100-2421, Novus), mouse anti-human ICAM1 (1:100, clone W-CAM-1, MA5-13021, Invitrogen, Waltham, MA, USA), sheep

(9) Lung injury-induced activated endothelial cell states persist in aging-associated progressive fibrosisNature communicationsJanuary 1, 0001"Raslan AA, Pham TX, Lee J, Kontodimas K, Tilston-Lunel A, Schmottlach J, Hong J, Dinc T, Bujor AM, Caporarello N, et al."mouse antibody (3528, clone 89C2, Cell Signaling Technology, 1:200 dilution), anti-ACKR1 goat antibody (NB100-2421, Novus, 1:200 dilution), anti-Col1α1 antibody (72026, clone E8F4L, Cell Signaling Technology, 1:200

(10) Mediators of Capillary-to-Venule Conversion in the Chronic Inflammatory Skin Disease PsoriasisThe Journal of investigative dermatologyJanuary 1, 0001"He Y, Kim J, Tacconi C, Moody J, Dieterich LC, Anzengruber F, Maul JT, Gousopoulos E, Restivo G, Levesque MP, et al."

(11) Absence of multiple atypical chemokine binders (ACBs) and the presence of VEGF and MMP-9 predict axillary lymph node metastasis in early breast carcinomas"Medical oncology (Northwood, London, England)"January 1, 0001"Zeng XH, Ou ZL, Yu KD, Feng LY, Yin WJ, Li J, Shen ZZ, Shao ZM."

(12) "Atypical Chemokine Receptor 1 (DARC/ACKR1) in Breast Tumors Is Associated with Survival, Circulating Chemokines, Tumor-Infiltrating Immune Cells, and African Ancestry""Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology"January 1, 0001"Jenkins BD, Martini RN, Hire R, Brown A, Bennett B, Brown I, Howerth EW, Egan M, Hodgson J, Yates C, et al."slides. DARC/ACKR1 staining was done using a goat anti-human polyclonal antibody (Novus Biologicals, NB100–2421, Isotype IgG). CCL2 and CXCL8 staining were both done using mouse anti-human monoclonal antibodies (R&D Systems

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DARC Antibody

DARC Antibody

DARC Antibody

DARC Antibody

DARC Antibody

DARC Antibody from Novus Biologicals, a Bio-Techne Brand

Specifications/Features

Novus Biologicals, a Bio-Techne Brand

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DARC Antibody from Novus Biologicals, a Bio-Techne Brand

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