Phospho-PLK Binding Motif (ST*P) (D73F6) Rabbit mAb 5243S from Cell Signaling Technology

Product Specs
ItemPhospho-PLK Binding Motif (ST*P) (D73F6) Rabbit mAb
CompanyCell Signaling Technology
Price $401.00 Inquire
Catalog Number5243S
Quantity100 µl
ApplicationsW, IP, E-P
ReactivityAll
HostRabbit
ClonalityMonoclonal
Research AreaMotif Antibodies
IsotypeIgG
ModificationsPLK Binding Motif (s/tP) phosphate
CloneD73F6

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) A cell cycle-dependent transition of acetylation to phosphorylation regulates timely centrosome maturationNat CommunMarch 20, 2026Jimin Li, Jianqiang Liang, Guifang Chen, Xuejie Wang, Yanyan Wang, Jingfei Zhan, Yunjing Guo, Jiadong Wang, Xuefeng ChenAb17056, 1:100 for IF, 1:1000 for WB); anti-Phospho-PLK1 Binding Motif (S/T*P)(Cell Signaling Technology, 5243, 1:1000 for WB); anti-PLK1-pT210 (Abcam, ab155095, 1:1000 for WB), anti-PCNT(Abcam, ab4448, 1:2000 for

(2) Mutant p53 protein accumulation is selectively targetable by proximity-inducing drugsNature Chemical BiologyNovember 3, 2025Ananthan Sadagopan, Maximilian Carson, Eriks J. Zamurs, Nicholas Garaffo, Heng-Jui Chang, Stuart L. Schreiber, Matthew Meyerson, William J. GibsonCell Signaling Technologies, 12231T; 1:1,000) and phospho-PLK-binding motif (D73F6, Cell Signaling Technologies, 5243T; 1:1,000). The membrane was stained with IRDye 800CW goat anti-rabbit IgG secondary antibody (Licor

(3) Lysosomes mediate the mitochondrial UPR via mTORC1-dependent ATF4 phosphorylationCell discoverySeptember 7, 2023Li TY, Wang Q, Gao AW, Li X, Sun Y, Mottis A, Shong M, Auwerx J.2972, CST, 1:1000), Phospho-S*P (Cat. 2325, CST, 1:1000; for detecting P-S166-ATF4), Phospho-ST*P (Cat. 5243, CST, 1:1000; for detecting P-T173-ATF4), and HRP-labeled anti-rabbit (Cat. 7074, CST, 1:5000), anti-rabbit

(4) Activity-dependent post-translational regulation of palmitoylating and depalmitoylating enzymes in the hippocampusJournal of cell scienceApril 1, 2023Abazari D, Wild AR, Qiu T, Dickinson BC, Bamji SX.Santa Cruz Biotechnology, sc-514005), anti-phospho-PLK binding motif (ST*P) (1:1000, Cell Signaling Technology, 5243S), anti-HA (1:1000, Cell Signaling Technology, C29F4), anti-myc (1:1000, Cell Signaling Technology, 2276),

(5) Revisiting the multisite phosphorylation that produces the M-phase supershift of key mitotic regulatorsMolecular biology of the cellOctober 1, 2022Tan T, Wu C, Liu B, Pan BF, Hawke DH, Su Z, Liu S, Zhang W, Wang R, Lin SH, et al.phosphospecific antibodies used to immunoblot SpTP or RXXpS/T motif were obtained from Cell Signaling Technology (5243 and 9614). In all of the immunoblotting performed in this study, horseradish peroxidase–conjugated goat

(6) Global profiling of phosphorylation-dependent changes in cysteine reactivityNature methodsMarch 1, 2022Kemper EK, Zhang Y, Dix MM, Cravatt BF.1:500 CCNB1 (Santa Cruz, sc-245), 1:500 CCNE1 (Santa Cruz, sc-247), 1:1,000 anti-SpTP (Cell Signaling, #5243), 1:1,000 anti-MAP2K4 (Cell Signaling, #9152), 1:1,000 anti-phospho-MAP2K4 (Cell Signaling, #9156),

(7) Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organizationNature Reviews Molecular Cell BiologyApril 1, 2021Ci Ji Lim, Thomas R. CechMammalian CST averts replication failure by preventing G-quadruplex accumulation. Nucleic Acids Res 47, 5243–5259 (2019). [PubMed: 30976812] 125. Wang F, Stewart J & Price CM Human CST abundance determines recovery

(8) Recent Developments in Small-Molecule Ligands of Medicinal Relevance for Harnessing the Anticancer Potential of G-QuadruplexesMoleculesFebruary 5, 2021Loukiani Savva, Savvas N. GeorgiadesCST averts replication failure by preventing G-quadruplex accumulation. Nucleic Acids Res. 2019, 47, 5243–5259. [CrossRef] [PubMed] Vannier, J.-B.; Pavicic-Kaltenbrunner, V.; Petalcorin, M.I.; Ding, H.; Boulton,

(9) miR-376a Provokes Rectum Adenocarcinoma Via CTC1 Depletion-Induced Telomere DysfunctionFrontiers in cell and developmental biologyJanuary 1, 2021Liu Y, Zhao X, Wang B, Liu Z, Zhang M, Wang J, Xu C, Wang Y, Du L, Wang F, et al.Mammalian CST averts replication failure by preventing G-quadruplex accumulation. Nucleic Acids Res. 47, 5243–5259. doi: 10.1093/nar/gkz264 Zhu, Y., Liu, X., Ding, X., Wang, F., and Geng, X. (2019). Telomere and

(10) G-quadruplexâ€“R-loop interactions and the mechanism of anticancer G-quadruplex bindersNucleic Acids ResearchDecember 2, 2020Giulia Miglietta, Marco Russo, Giovanni CapranicoMammalian CST averts replication failure by preventing G-quadruplex accumulation. Nucleic Acids Res., 47, 5243–5259. Zeman,M.K. and Cimprich,K.A. (2014) Causes and consequences of replication stress. Nat. Cell Biol.,

(11) DETECTION OF SPECIFIC SURFACTANT PROTEINS IN GASTRIC ASPIRATES FROM PREMATURELY BORN CHILDREN AFTER CORTICOSTEROID THERAPYJournal of IMAB - Annual Proceeding (Scientific Papers)November 20, 2020Vishnya Stoyanova, Department of Chemistry and Biochemistry, Physiology and Pathophysiology, Faculty of Medicine, St. Kliment Ohridsky University of Sofia, Bulgaria, Asya Tsanova, Albena Jordanova, Neli Jekova, Detelina Stoichkova, Krasimira Ivanova, Emilia Hristova, Department of Chemistry and Biochemistry, Physiology and Pathophysiology, Faculty of Medicine, St. Kliment Ohridsky University of Sofia, Bulgaria, Department of Chemistry and Biochemistry, Physiology and Pathophysiology, Faculty of Medicine, St. Kliment Ohridsky University of Sofia, Bulgaria, et al.SDS-PAGE (12%) of GAs under reducing conditions: 1 - 4108; 2 - 4101; 3 - 4899; 4 - 2180; 5 - 5241; 6 - 5243; 7 - 4099; 8 - bovine serum albumin; 9 - human serum albumin, 10 - protein standards. 3460 SP-B is

(12) Phosphoregulation of HORMA domain protein HIM-3 promotes asymmetric synaptonemal complex disassembly in meiotic prophase in Caenorhabditis elegansPLoS geneticsNovember 1, 2020Sato-Carlton A, Nakamura-Tabuchi C, Li X, Boog H, Lehmer MK, Rosenberg SC, Barroso C, Martinez-Perez E, Corbett KD, Carlton PM.CST (catalog numbers 9607, 6966, 8139, 8738, 9624, 6967, 5759, 9942, 10001, 9614, 9477, 8134, 2325, 5243, and 3004). Protein assignments were made using Sorcerer. Peptide counts indicated in S1 Table show

(13) Roles of OB-Fold Proteins in Replication StressFrontiers in Cell and Developmental BiologySeptember 11, 2020Dinh-Duc Nguyen, Eugene Y. Kim, Pau Biak Sang, Weihang ChaiMammalian CST averts replication failure by preventing G-quadruplex accumulation. Nucleic Acids Res. 47, 5243–5259. doi: 10.1093/nar/gkz264 Zou, L., and Elledge, S. J. (2003). Sensing DNA damage through ATRIP recognition of

(14) G-Quadruplexes at Telomeres: Friend or Foe?MoleculesAugust 13, 2020Tracy M. BryanCST averts replication failure by preventing G-quadruplex accumulation. Nucleic Acids Res. 2019, 47, 5243–5259. [CrossRef] 126. Arthanari, H.; Bolton, P.H. Did quadruplex DNA play a role in the evolution of

(15) The regulation and functions of DNA and RNA G-quadruplexesNature Reviews Molecular Cell BiologyAugust 1, 2020Dhaval Varshney, Jochen Spiegel, Katherine Zyner, David Tannahill, Shankar BalasubramanianCST averts replication failure by preventing G-quadruplex accumulation. Nucleic Acids Res. 2019; 47:5243–5259. [PubMed: 30976812] 40. Wu W, et al. HERC2 facilitates BLM and WRN helicase complex interaction

(16) Functional Diversification of Replication Protein A Paralogs and Telomere Length Maintenance in ArabidopsisGeneticsAugust 1, 2020Behailu B Aklilu, FranÃ§ois Peurois, Carole SaintomÃ©, Kevin M Culligan, Daniela Kobbe, Catherine Leasure, Michael Chung, Morgan Cattoor, Ryan Lynch, Lauren Sampson, et al.Mammalian CST averts replication failure by preventing G-quadruplex accumulation. Nucleic Acids Res. 47: 5243–5259. https://doi.org/ 10.1093/nar/gkz264 Communicating editor: A. Britt Downloaded from https://academic.oup.com/genetics/article/215/4/989/6065541

(17) Kinase inhibition profiles as a tool to identify kinases for specific phosphorylation sitesNature communicationsApril 3, 2020Watson NA, Cartwright TN, Lawless C, Cámara-Donoso M, Sen O, Sako K, Hirota T, Kimura H, Higgins JMG.Sigma, T3320); rabbit monoclonal antibodies to the S-pT-P motif (D73F6; Cell Signaling Technology #5243), Cyclin B1 (D5C10; Cell Signaling Technology #12231) and Vinculin (E1E9V; Cell Signaling Technology

(18) Clinical Relevance and Molecular Pathogenesis of the Emerging Serotypes 22F and 33F of Streptococcus pneumoniae in SpainFrontiers in MicrobiologyFebruary 27, 2020Julio Sempere, Sara de Miguel, Fernando González-Camacho, José Yuste, Mirian Domenechyears,22F,37,0.48,168,0.69,230,0.68,154,0.87,1.83,1.28–2.62,1.26,1.01–1.57,1.29,1.1–1.51 ,33F,13,0.17,39,0.16,73,0.21,59,0.33,2.00,1.1–3.64,2.08,1.39–3.11,1.56,1.21–2.01 Total IPD by all serotypes,Total IPD by all serotypes,3099,6.63,7009,4.95,8096,4.32,5243,5.62,0.85,0.81–0.89,1.13,1.09–1.18,1.30,1.25–1.34 Number of cases and incidence of IPD in 2017–2018

(19) Regulation of folate and methionine metabolism by multisite phosphorylation of human methylenetetrahydrofolate reductaseScientific ReportsDecember 1, 2019Yuxiang Zheng, Shivan Ramsamooj, Qian Li, Jared L. Johnson, Tomer M. Yaron, Klaus Sharra, Lewis C. CantleyDYRK1A, GSK3A/B, GSK3A, P-glycogen synthase antibodies was purchased from Cell Signaling Technology (Cat# 5243, Cat# 2771, Cat#5676, Cat#4818, Cat#94905 respectively). DYRK inhibitor harmine was purchased from Sigma-Aldrich

(20) Quantitative phosphoproteomic analysis of the molecular substrates of sleep needNatureJune 13, 2018Zhiqiang Wang et al.anti-Phospho-CDKs Substrate Motif [(K/H)S*P] [#9477, Cell Signaling], anti-Phospho-PLK Binding Motif [ST*P] [#5243, Cell Signaling], anti-Phospho-Thr-Pro Motif [T*P, T*PP] [#3003, Cell Signaling], anti-Phospho-Thr-Pro-Glu

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Phospho-PLK Binding Motif (ST*P) (D73F6) Rabbit mAb

Phospho-PLK Binding Motif (ST*P) (D73F6) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Phospho-PLK Binding Motif (ST*P) (D73F6) Rabbit mAb from Cell Signaling Technology

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