11 beta-HSD1 Antibody AF3397 from R&D Systems, a Bio-Techne Brand

Product Specs
Item11 beta-HSD1 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $479.00Supplier Page View Company Product Page
Catalog NumberAF3397
NCBI Gene Aliases11-DH, HSD11B, HSD11L, HSD11, SDR26C1, HDL, 11-beta-HSD1, CORTRD2
ApplicationsImmunoprecipitation,Western Blot
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
IsotypeIgG
Target11 beta-HSD1
Quantity100 ug (also 25 ug)
Conjugate/TagUnconjugated
ReactivityHuman,Mouse,Rabbit,Rat
HostGoat
NCBI Full Gene Namehydroxysteroid 11-beta dehydrogenase 1
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant human 11ß-HSD1, Asn24-Lys292, Accession # P28845
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects endogenous human, mouse and rat 11ß-HSD1 in Western blots.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Effect of glucocorticoid production by the enteric nervous system on neuronal connectivity is blocked during inflammation in a GR-dependent pathwayiScienceAugust 21, 2026Justine Blin, Valentine S. Moullé, Zoé Garel, Ulysse Bertholon, Thibauld Oullier, Tony Durand, Catherine Le Berre-Scoul, Damien Masson, Kalyane Bach-Ngohou, Michel Neunlistanti-nNOS,BD Biosciences,Cat# 610308; RRID:AB_397700 Goat monoclonal anti-11β-HSD1,Biotechne,Cat# AF3397 Rabbit monoclonal anti-11β-HSD2,Proteintech,Cat# 14192-1-AP; RRID:AB_2119643 Mouse monoclonal anti-β-actin

(2) Magnesium isoglycyrrhizinate alleviates alcohol-associated liver disease through targeting HSD11B1ElifeJuly 28, 2026Lu Xiao, Lu Li, Shasha Wu, Zhaoyi Che, Yuyang Du, Jingyi Zheng, Jingsong Yan, Hao Wang, Hong Zhang, Yan Li, et al.and SREBP2 (#28212-1-AP) were obtained from Proteintech (Wuhan, China). An antibody against HSD11B1 (#AF3397) was purchased from R&D Systems (Minneapolis, MN, USA). A Flag antibody (F1804) was purchased from Sigma-Aldrich.

(3) Transcriptome Analysis of Platelet‐Rich Plasma–Treated Osteoarthritic ChondrocyteBioMed Research InternationalNovember 21, 2024Dae Keun Suh, Woo Jin Yeo, Kuhoang Cheong, Jae-Won Heo, Dong Hyeon Kim, Soo Mi Lee, Yong-Soo Lee, Dong Won Suhmembranes were probed with anti-MMP3 (sc21732, Santa Cruz Biotechnology, Dallas, TX, USA), anti-11β-HSD1 (AF3397, R&D system, Minneapolis, MN, USA), anti-Ki-67 (MA5-14520, Invitrogen), anti-CDK1/CDK2 (sc53219, Santa Cruz

(4) Targeting osteoblastic 11β-HSD1 to combat high-fat diet-induced bone loss and obesityNature CommunicationsOctober 4, 2024Chuanxin Zhong, Nanxi Li, Shengzheng Wang, Dijie Li, Zhihua Yang, Lin Du, Guangxin Huang, Haitian Li, Wing Sze Yeung, Shan He, et al.Signaling, USA), phosphorylated AKT (4060 T, pAKT, Cell Signaling, USA), Glut4 (21619, SAB, USA), 11β-HSD1 (AF3397, R&D system, USA), Egr2 (EPR4004, Abcam, UK), H6PDH (EPR12338, Abcam, UK). After incubation with appropriate

(5) 11-beta-hydroxysteroid dehydrogenase type 1 (HSD11B1) gene expression in muscle is linked to reduced skeletal muscle index in sarcopenic patientsAging Clinical and Experimental ResearchNovember 9, 2023Sabine Schluessel, Wei Zhang, Hanna Nowotny, Martin Bidlingmaier, Stefan Hintze, Sonja Kunz, Sebastian Martini, Stefan Mehaffey, Peter Meinke, Carl Neuerburg, et al.GAPDH (Merck Millipore #MAB374) was used for normalization and the anti-h/m/r11β-HSD1 (R&D Systems #AF3397) was used to detect HSD11B1. As secondary antibodies we used donkey anti-mouse IRDye 680RD (LI-COR#

(6) The GR-gp78 Pathway is involved in Hepatic Lipid Accumulation Induced by Overexpression of 11β-HSD1International journal of biological sciencesJanuary 1, 2022Hu M, Han T, Pan Q, Ni D, Gao F, Wang L, Ren H, Zhang X, Jiao H, Wang Y, et al.anti-Insig1 antibody (ab70784) was were purchased from Abcam (Cambridge, UK). The anti-11β-HSD1 antibody (AF3397) was purchased from R&D System (Abingdon, UK). The anti-β-actin antibody (TA-09), anti-β-tubulin antibody

(7) Corticosterone and Glucocorticoid Receptor in the Cortex of Rats during Aging-The Effects of Long-Term Food RestrictionNutrientsDecember 17, 2021Tesic V, Ciric J, Jovanovic Macura I, Zogovic N, Milanovic D, Kanazir S, Perovic M.

(8) NAFLD Aggravates Septic Shock Due to Inadequate Adrenal Response and 11β-HSDs Dysregulation in RatsPharmaceuticsApril 28, 2020Huang HC, Tsai MH, Lee FY, Lin TY, Chang CC, Chuang CL, Hsu SJ, Hou MC, Huang YH.Tween 20). Blots were incubated with the primary antibody [11β-HSD1 from R&D Systems, Minneapolis, MN, USA (AF3397); 11β-HSD2 from Millipore, Merk KGaA, Darmstadt, Germany (AB1296); G6PD from GeneTex Inc., Irvine, CA,

(9) S100A16-induced adipogenesis is associated with up-regulation of 11 β-hydroxysteroid dehydrogenase type 1 (11β-HSD1)Bioscience reportsSeptember 30, 2019Zhang R, Kan JB, Lu S, Tong P, Yang J, Xi L, Liang X, Su D, Li D, Liu Y.Image Lab Software (Version 4.0.1, Bio-Rad Laboratories, Hercules, CA, U.S.A.). Antibodies for 11β-HSD1 (AF3397) were purchased from R&D SYSTEMS, α-Tubulin (T5168) antibody was purchased from Sigma-Aldrich (St. Louis, MO),

(10) Saturated fatty acids in human visceral adipose tissue are associated with increased 11- β-hydroxysteroid-dehydrogenase type 1 expressionLipids in health and diseaseMay 2, 2015Petrus P, Rosqvist F, Edholm D, Mejhert N, Arner P, Dahlman I, Rydén M, Sundbom M, Risérus U.

(11) Identification of cytochrome P450 2C2 protein complexes in mouse liverProteomicsAugust 1, 2011Li B, Yau P, Kemper B.

(12) Renal interstitial corticosterone and 11-dehydrocorticosterone in conscious ratsAmerican Journal of Physiology-Renal PhysiologyJuly 1, 2007Kristie Usa, Ravinder J. Singh, Brian C. Netzel, Yong Liu, Hershel Raff, Mingyu LiangA goat antibody for human 11␤-HSD1 was obtained from R&D Systems (Minneapolis, MN), catalog number AF3397, and used at a final concentration of 0.5 ␮g/ml. The antibody detected a distinct band at the expected

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11 beta-HSD1 Antibody

11 beta-HSD1 Antibody

11 beta-HSD1 Antibody

11 beta-HSD1 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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11 beta-HSD1 Antibody from R&D Systems, a Bio-Techne Brand

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