SOX1 Antibody AF3369 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemSOX1 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $519.00Supplier Page View Company Product Page
Catalog NumberAF3369
ApplicationsBioassay,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Simple Western,Immunocytochemistry
ReactivityCanine,Human,Mouse,Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque),Rabbit,Rat,Transgenic Mouse,Xenograft
TargetSOX1
Conjugate/TagUnconjugated
Quantity100 ug (also 25 ug)
IsotypeIgG
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
HostGoat
NCBI Full Gene NameSRY-box transcription factor 1
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant human SOX1, Asn242-Gly379 (Leu276Ile), Accession # NP_005977
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human SOX1 in direct ELISAs and Western blots.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Hedgehog signaling activation rescues hypoxia-induced ferroptosis in human brain organoidsNeural regeneration researchSeptember 1, 2026Yi S, Huang M, Xian C, Kong X, Yin S, Peng J, Li H, Jiang Y, Xie B, Xie H.

(2) The microtubule-binding protein EML3 is required for mammalian embryonic growth and cerebral cortical development, and Eml3 null mice are a model of cobblestone brain malformationElifeJuly 9, 2026Isabelle Carrier, Eduardo Diez, Valerio E Piscopo, Susanne Bechstedt, Hans van Bokhoven, Myriam Srour, Albert M Berghuis, Stefano Stifani, Yojiro Yamanaka, Roderick McInnes(phospho-Histone H3) (NEB/Cell signaling 9706; 1:200), goat anti-SOX1 (Transcription factor SOX-1) (Novus AF3369; 1:40), rabbit anti-TBR1 (T-box brain protein 1) (Abcam ab31940; 1:5000), rabbit anti-TBR2 (Eomesodermin

(3) A pipeline for cell migration analysis in live-cell imaging data from human iPSC-derived forebrain assembloidsFront Cell Dev BiolJuly 1, 2026Maya P. Weidman, Natalie Baker Campbell, Cody Headings, Samantha Chung, Musarat Khan, Aarnav Kandukuri, Vianne Lim, Gloria Olubowale, Michelle J. Kim, Anna Devor, et al.Primary antibodies: rabbit anti-GABA (1:250; cat. A2052, MilliporeSigma); goat anti-SOX10 (1:100; cat. AF3369, R&D Systems) used to characterize EYFP+ cell type identity. Secondary antibodies: anti-rabbit Alexa

(4) Generation of Functional Oligodendrocyte Progenitor Cells Through Serial Replating of iPSC-Derived NPC SpheresCellsJune 11, 2026Junmyeong Park, Seungye Kang, Soojin Kim, Donghyun Kim, Borami Shin, Ji Young Mun, Yurim Park, Johnny Kim, Steven A. Goldman, Kee-Pyo KimCell Signaling Technology, Danvers, MA, USA), anti-PAX6 (1:500, 901301, BioLegend, San Diego, CA, USA), anti-SOX1 (1:200, AF3369, R&D Systems, Minneapolis, MN, USA), anti-NESTIN (1:500, 60091, STEMCELL Technologies, Vancouver, BC,

(5) Aberrant chromatin remodeling influences human neural cell fate change in Trisomy 21bioRxivJune 2, 2026Jenny A. Klein, Suraj Upadhya, Anna Nathanson, Dana Silvian, Eric F. Zaniewski, Robert Morris, Wilhelm Haas, Lindy E. BarrettThermoFisher, 14-0441-82), chicken anti-MAP2 (1:1000, Abcam, ab5392), goat anti-SOX1, (1:500, R&D Systems, AF3369), rabbit anti-GFP (1:500, Abcam, ab6556), rabbit anti-CC3 (1:500, Cell Signaling Technologies 9661),

(6) Interplay between DYRK1A dosage and aneuploidy-induced neuropathology in Down syndromeCommunications BiologyMarch 24, 2026Toshihiko Nambara, Joo Yeon Lee, Masaki Minami, Soichiro Okamoto, Keiji Kawatani, Haruna Kusakabe, Hidetaka Yoshimatsu, Katsuya Hirata, Kazuto Yoshimi, Tomoji Mashimo, et al.#PM045, MBL, Tokyo, Japan), anti-PRDX3 (1:1000; #ab73349, Abcam, Cambridge, UK), anti-SOX1 (1:100; #AF3369, R&D Systems), or anti-vimentin (1:500; #V2258, Merck). The cells were then washed with PBS and incubated

(7) Mitochondrial metabolic imbalance drives diploidization in mouse haploid embryonic stem cells via NADPH overloadNature CommunicationsMarch 24, 2026Giulio Di Minin, Anna B. Rüegg, Kevin Halter, Tobias Fuhrer, Tatjana Kleele, Nicola Zamboni, Anton Wutzover-night. FLAG (1:100, Biolegend #637301), COX4 (1:100, CellSignaling #11967), Sox1 (1:50, R&D Systems, # AF3369), Nestin (1:200, Sigma MAB353), p-Aurora A/B (1:50, CellSignaling #2914), Acetyl-Tubulin (1:500, Sigma

(8) Blood Serum From Obese Women Raises ROS Production by Neural Stem CellsDev NeurobiolMarch 17, 2026Phelipe Elias da Silva, Natássia Caroline Resende Corrêa, Natália Ferreira Silva, Carlos Ueira-Vieira, Hebreia Oliveira Almeida-Souza, Mario Machado Martins, Tiara da Costa Silva, Renata Graciele Zanondescription,Dilution,Commercial specification,Function Primary,"Anti‐SOX1 (polyclonal, goat, IgG)",1:300,"R&D Systems, AF3369, Inc. a Bio‐Techne Brand, Minneapolis, USA",Neuroectoderm induction; specification of neural precursors

(9) Antisense oligonucleotides to KIF1A polymorphisms expand targets and rescue patient-derived neurons in vitroNature communicationsJanuary 9, 2026Zuccaro MV, Young RE, Hu J, Lanzano P, Semenova E, Lin X, Skowronski A, Shen Y, Kim TH, Miller DE, et al.media. Immunostaining Post NSC induction, immunofluorescent staining was performed for SOX1 (R&D Systems AF3369) at 1:500 and Nestin (R&D Systems MAB2736) at 1:200. Secondaries NorthernLights™ 557-conjugated Anti-Goat

(10) Stem cell-based approach to identify regulatory TFs during mammalian cell differentiationStem cell reportsDecember 9, 2025Pei Y, Li S, Garipler G, Kamimoto K, Mazzoni EO.

(11) Generation of two isogenic induced pluripotent stem cell lines derived from a Hispanic individual with Alzheimer’s Disease and mosaic for loss of the Y chromosomeStem Cell ResearchDecember 1, 2025Holly N. Cukier, Brooke A. DeRosa, Lauren E. Coombs, Eugene Tang, Denise R. Leyva, Ainnara R. Lazzaro, Esther Gu, Derek M. Dykxhoorn, Jonathan L. Haines, Margaret A. Pericak-Vance, et al.,Cell Signaling Technologies Cat # 3579 s,RRID: AB_2195767 Differentiation marker,Goat anti-SOX1,1:50,R&D Systems Cat# AF3369,RRID: AB_2239879 Differentiation marker,Rabbit anti-PAX6,1:100,Thermo Fisher Cat # 42-6600,RRID: AB_2533534 Differentiation

(12) CTCF-RNA interactions orchestrate cell-specific chromatin loop organizationScience advancesNovember 28, 2025Lucero K, Han S, Huang PY, Qiu X, Mazzoni EO, Reinberg D.

(13) Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cellsNature Cell BiologySeptember 29, 2025Kaitlin P. McCreery, Aki Stubb, Rebecca Stephens, Nadezda A. Fursova, Andrew Cook, Kai Kruse, Anja Michelbach, Leah C. Biggs, Adib Keikhosravi, Sonja Nykänen, et al.1:200), LAMINB1 (66095-1-Ig, Proteintech; 1:200), Pax6 (Invitrogen, #42-6600; 1:1000), SOX1 (R&D Systems, AF3369; 1:200), SOX7 (R&D Systems, AF1924; 1:1,000), YAP1 (Santa Cruz sc-101199; 1:200), p38 MAPK phosphoThr180/Tyr182

(14) Functional Recovery by Transplantation of Human iPSC-Derived A2B5 Positive Neural Progenitor Cell After Spinal Cord Injury in MiceInternational journal of molecular sciencesSeptember 13, 2025Zheng Y, Chen X, Bu P, Xue H, Kim DH, Zhou H, Xia X, Liu Y, Cao Q.Developmental Studies Hybridoma Bank, DSHB, cat. no. AB_528427), and SOX1 (1:200, R&D Systems, cat. no. AF3369). Bis-benzamide (DAPI, 1:1000, Sigma) was used to visualize the nuclei. Images were captured using a

(15) Directed and efficient generation of calretinin interneurons from human pluripotent stem cellsStem Cell Res TherAugust 27, 2025Xuewei Du, Renli Qi, Congge Li, Wenpei Zhou, Shijiao Wang, Shenxing Wei, Runzhong Wu, Yu Yin, Tianqing Li, Xiaoqing Zhuantibodies were described in followings. Primary antibodies were used at 1:200–1:2000: SOX1, goat (AF3369, R&D Systems); TUJ1, mouse (MAB1637, Millpore); NESTIN, mouse (MAB5326, Millpore); PAX6, rabbit (901301,

(16) Derivation and Culture of Enriched Phrenic-Like Motor Neurons From Human iPSCsBIO-PROTOCOLJuly 5, 2025Louise Thiry, Julien Sirois, Thomas M. Durcan, Stefano StifaniMillipore, catalog number: T8787) 32. Goat anti-SRY-BOX 1 (SOX1), 1/500 (R&D Systems, catalog number: AF3369) 33. Rabbit anti-HOMEOBOX C4 (HOXC4), 1/150; kindly provided by Dr. Jeremy Dasen, New York University

(17) Derivation and Culture of Enriched Phrenic-Like Motor Neurons From Human iPSCsBio ProtocJuly 5, 2025Louise Thiry, Julien Sirois, Thomas M. Durcan, Stefano StifaniMillipore, catalog number: T8787) 32. Goat anti-SRY-BOX 1 (SOX1), 1/500 (R&D Systems, catalog number: AF3369) 33. Rabbit anti-HOMEOBOX C4 (HOXC4), 1/150; kindly provided by Dr. Jeremy Dasen, New York University

(18) Macrophage Migration Inhibitory Factor Suppresses Natural Killer Cell Response and Promotes Hypoimmunogenic Stem Cell Engraftment Following Spinal Cord InjuryBiologyJune 30, 2025Li S, Zheng Y, Xue H, Zhang H, Wu J, Chen X, Perez Bouza M, Yi S, Zhou H, Xia X, et al.

(19) Macrophage Migration Inhibitory Factor Suppresses Natural Killer Cell Response and Promotes Hypoimmunogenic Stem Cell Engraftment Following Spinal Cord InjurybioRxiv : the preprint server for biologyMay 7, 2025Li S, Zheng Y, Xue H, Zhang H, Wu J, Chen X, Bouza MP, Yi S, Zhou H, Xia X, et al.

(20) Generation of a chimeric astrocytic rat spinal cord model by engraftment of human dorsal spinal neural stem/progenitor cellsNeural Regen ResApril 29, 2025Wenjie Xu, Ziyu He, Jia Xu, Ruoying Zhang, Shu Fan, Zhixian Liu, Wei Wang, Hong Chen, Xiaolong Zhengnumber,RRID NeuN,Chicken,1:1000,"Millipore, Burlington, MA, USA",ABN91,AB_11205760 SOX1,Goat,1:200,"R&D Systems, Minneapolis, MN, USA",AF3369,AB_2239879 SOX2,Goat,1:200,R&D Systems,AF2018,AB_355110 SOX9,Goat,1:200,R&D Systems,AF3075,AB_2194160 NKX6.1,Goat,1:200,R&D Systems

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SOX1 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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SOX1 Antibody from R&D Systems, a Bio-Techne Brand

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