IL-6 Polyclonal Antibody bs-0782R from Bioss Inc.

Product Specs
ItemIL-6 Polyclonal Antibody
CompanyBioss Inc.
Price $375.00Supplier Page View Company Product Page
Catalog Numberbs-0782R
Molecular Weight23kDa
ImmunogenKLH conjugated peptide, mouse IL-6
Format0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol
ClonalityPolyclonal
Conjugate/TagUnconjugated
ApplicationsWB, ELISA, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC), WB, ELISA, WB, IHC, Others, IF(ICC), IHC-P, FCM, WB, IHC-P
ReactivityMouse, Rat, Human, Mouse, Rabbit, Human, Bovine
Antibody TypePrimary Antibody
Quantity100ul, 20uL
IsotypeIgG
HostRabbit
TargetIL-6
Concentration1ug/ul
NCBI Gene AliasesIl-6
NCBI Full Gene Nameinterleukin 6
Tissuethoracic aorta

Questions and Answers

What applications has the IL-6 Polyclonal Antibody been used for in scientific research?

The IL-6 Polyclonal Antibody has been shown to work in various applications including Western Blotting, ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, and Immunohistochemistry. It has been utilized in studies to assess inflammatory responses and cytokine production, particularly in the context of wound healing and immune modulation.

Can this antibody be used to study IL-6 in different species?

Yes, the IL-6 Polyclonal Antibody is reactive with multiple species, including humans, mice, rabbits, rats, and bovines. This broad reactivity allows researchers to use it in comparative studies across different animal models.

Are there any specific studies that highlight the effectiveness of this antibody in research?

Yes, the IL-6 Polyclonal Antibody has been cited in various studies, such as in the research by Chen et al. (2021), where it was used to measure IL-6 levels in the context of impaired wound healing in diabetic rats, demonstrating its role in inflammatory cytokine production.

How does the IL-6 Polyclonal Antibody contribute to understanding inflammatory processes?

The IL-6 Polyclonal Antibody is crucial for detecting IL-6 levels, a key cytokine involved in the acute phase response and inflammation. Studies have shown that it can help elucidate the mechanisms of inflammation, such as in the modulation of immune responses and the regulation of inflammatory factors like TNF-α and IL-1β in various experimental models.

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(1) Small extracellular vesicle-integrated by herbal hydrogels for spatiotemporal immunomodulation and neurovascular repair following traumatic brain injuryBioact MaterMarch 6, 2026Yao Wu, Yuanyuan Sun, Jingjing Chen, Mingrui Hu, Xindi Zhang, Xinyu Xiong, Zhe Yu, Xiya Yang, Hui Li, Yang Wangwere used: anti-iNOS (Ab178945, abcam, USA), CD206 (E6TSJ, Cell Signaling Technology, USA), anti-IL-6 (bs-0782R, Bioss, Beijing, China), anti-TNF-α (YT4689, ImmunoWay, USA), anti-IL-1β (AF02479, AiFang biological,

(2) Inhibition of focal adhesion kinase impairs tumor formation and preserves hearing in a murine model of NF2-related schwannomatosisScience AdvancesJanuary 30, 2026Dana K. Mitchell, Kylee Brewster, Li Jiang, Henry Mang, Waylan K. Bessler, Xiaohong Li, Qingbo Lu, Shaomin Qian, Eric York, Sarah K. Morrow, et al.antibodies for 30 min at room temperature [F4/80: #70076, Cell Signaling Technology (1:100); IL-6: #bs0782R, Bioss (1:100); MET: #ab216574 or #ab51067, Abcam (1:100); SOX10: #ab180862, Abcam (1:100); NLRP3: #CAB12694,

(3) Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathwayMolecular Medicine ReportsJanuary 22, 2026Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wutemperature, then incubated at 4°C overnight with primary antibodies against IL-6 (1:1,000; cat. no. Bs-0782R; BIOSS), phosphorylated (p-)JAK2 (1:1,000; cat. no. bs-2485R; BIOSS), JAK2 (1:1,000; cat. no. bs-0908R;

(4) Manifold hepatoprotective actions of α-lipoic acid on metabolic function through redox regulation, inflammatory modulation, and anti-apoptosis after chronic sleep-deprived injuryFrontiers in NutritionJanuary 22, 2026Hung-Ming Chang, Hsing-Chun Lin, Ting-Yi Renn, Yu-Cheng Liu, Kai-Jung Yen, Chih-Kai Liao, Maria A. Tikhonova, Tamara G. Amstislavskaya, Sandeep Kumar Singh, Li-You Chenwith the following primary antibodies: NF-κB (p65) (1:200, Santa Cruz, sc-8008), IL-6 (1:500, Bioss bs-0782R-TR), COX2 (1:200, Santa Cruz, sc-376861), BAX (1:100, Santa Cruz, sc-7480), Bcl-2 (1:200, Millipore,

(5) Metformin carbon dots-based osteogenic and protein delivery system to promote bone regeneration in periodontitisBioactive MaterialsNovember 1, 2025Jingjing Wei, Kai Wang, Yongkai Li, Jiao Huang, Ping Deng, Xianbo Xia, Cong Yang, Ling Xu, Junji XuCD90(ab307736) were procured from Abcam (Cambridge, MA, USA). Antibodies against IL-1β(bs-0812R)、IL-6(bs-0782R) were obtained from Bioss (Beijing, China). OCN (YN2113) was sourced from Immunoway (Suzhou, China).

(6) Ubiquitin-specific protease 7 regulates macrophage polarization via pyruvate kinase M2-mediated metabolic reprogramming in severe acute pancreatitisCell Death DisOctober 27, 2025Yao Wu, Xudong Yao, Qiang Yu, Qingqing Yan, Xin Huang, Huajing Ke, Chao Peng, Liang Xia(1:1000, #AF4006, Affinity Biosciences), anti-TNF-α (1:500, #AF7014, Affinity Biosciences), anti-IL-6 (bs-0782R, bs-0782R, Bioss), anti-CD206 (1:500, #DF4149, Affinity Biosciences), anti-IL-10 (1:1000, #DF6894, Affinity Biosciences

(7) Low-Dose, Post-Storage Dancong Tea Attenuates Hydroalcohol-Induced Gastric Damage via Modulation Antioxidant and Anti-Inflammatory PathwaysFoodsAugust 12, 2025Huanwei Jian, Ruohong Chen, Lingli Sun, Qiuhua Li, Junxi Cao, Xingfei Lai, Zhenbiao Zhang, Suwan Zhang, Mengjiao Hao, Shili Sun, et al.heme oxygenase 1 (HO-1, Bioss, bs2075R, Beijing, China, Rabbit, 1:500), interleukin-6 (IL-6, Bioss, bs-0782R, Beijing, China, Rabbit, 1:500), tumor necrosis factor-α (TNF-α, Proteintech, 26405-1-AP, Wuhan, China,

(8) Synbiotic Administration of d-Tagatose and Lacticaseibacillus casei ATCC 393 Improves Hyperlipidemia in BALB/c Mice by Modulating Gut Microbiota and Metabolic ParametersFood Sci NutrJuly 10, 2025Mehmet Cavdar, Nalan Hakime Nogay, Emine Dincer, Derya Karabulut, Muge Gulcihan Onal, Serkan BolatImmunohistochemistry Analysis Immunohistochemistry procedure was performed with IL‐6 polyclonal antibodies (Bioss Antibodies, BS‐0782R, Massachusets, USA) to demonstrate IL‐6 immunoreactivity in liver sections. Paraffinized sections kept

(9) Notch signaling pathway regulates the progression of fetal growth restriction through mediating immune dysfunctionBiomed RepMay 6, 2025Liyan Ye, Xiujuan Zheng, Yali Yang, Ying Lyu19003-1-AP), GAPDH (1:50,000; cat. no. 60004-1-Ig; all from Proteintech Group, Inc.), IL-6 (1:1,000; cat. no. bs-0782R), placental growth factor (PLGF; 1:1,000; cat. no. bsm-54066R; both from BIOSS), C-X-C motif chemokine

(10) M2 Macrophage‐Derived Extracellular Vesicles Reprogram Immature Neutrophils into Anxa1hi Neutrophils to Enhance Inflamed Bone RegenerationAdvanced ScienceApril 25, 2025Yufei Yao, Yijia Yin, Fangyuan Shuai, Waishan Lam, Tao Zhou, Yaxin Xie, Xuesong He, Xianglong Hanwith primary antibodies Anti‐ALP (#ET1601‐21, Huabio), Anti‐IL‐6 (#AF5103, Affinity) and Anti‐IL‐1β (#bs‐0782R, Bioss). Following primary antibody incubation, the sections were stained with secondary antibodies

(11) Febrile temperature-regulated TRPV1 in CD4(+) T cells mediates neuroinflammation in complex febrile seizuresJournal of neuroinflammationApril 7, 2025Kong S, Jia X, Liang X, Chen Y, Liang J, Zhang Y, Wu N, Su S, Chen T, He X, et al.(IF) Anti-P38,Proteintech (14064-1-AP),1:1000 (WB) Anti-P-P38,Proteintech (28796-1-AP),1:1000 (WB) Anti-IL-6,Bioss (bs-0782R),1:500 (WB) Anti-TNF-α,ABclonal (A0277),1:500 (WB) Anti-β-actin,Proteintech (66009-1-Ig),1:5000 (WB) Anti-GAPDH,Proteintech

(12) A novel senotherapeutic strategy with azithromycin for preventing endometriosis progressionReprod Biol EndocrinolMarch 26, 2025Reina Sonehara, Tomoko Nakamura, Takehiko Takeda, Satoshi Kaseki, Tomomi Seki, Hideaki Tanaka, Atsushi Yabuki, Natsuki Miyake, Ayako Muraoka, Satoko Osuka, et al.manufacturer’s instruction. Primary antibodies were Ki67 (ab9260, 1:500, Abcam, Cambridge, UK), IL-6 (bs-0782R, 1:200, Bioss Antibodies, Woburn, MA, USA), PAX8 (ab97477, 1:2000, Abcam, Cambridge, UK), and PgR (ab16661,

(13) Alveolar epithelial type 2 cell specific loss of IGFBP2 activates inflammation in COVID-19Respiratory researchMarch 22, 2025Pujadas V, Chin C, Sankpal NV, Buhrmaster J, Arjuna A, Walia R, Smith MA, Eickelberg O, Bremner RM, Mohanakumar T, et al.(Novus Biologicals; catalog# NBP248510, 1:200), TNF-α (ABclonal; catalog# A11534, 1:5000), IL6 (Bioss Inc; catalog# bs-0782R, 1:150), CCR5 (Proteintech; catalog# 17476–1-AP, 1:800). Images were acquired at 63X magnification by

(14) Effect and Mechanism of Aloin in Ameliorating Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Network Pharmacology and Experimental VerificationDrug Des Devel TherMarch 14, 2025Rongxin Li, Yanan Wang, Yongfeng Lao, Chengyu You, Liangliang Qing, Xin Guan, Jian Wang, Xiaolong Li, Qingchao Li, Shuai Liu, et al.Interleukin-1 beta (IL-1β) antibody (bs-0812R, Bioss, China), anti-rabbit Interleukin-6 (IL-6) antibody (bs-0782R, Bioss, China), anti-rabbit Cyclooxygenase-2 (COX-2) antibody (TA7003, Abmart, China) and anti-rabbit

(15) Micheliolide attenuates sepsis-induced acute lung injury by suppressing mitochondrial oxidative stress and PFKFB3-driven glycolysisJ Transl MedFebruary 14, 2025Wenhan Li, Yuhan Li, Linjie Xiao, Zhanzhan Xie, Jun Peng, Wenhui Huang, Xu Li, Ying MengGAPDH (10,494–1-AP, Proteintech), iNOS (18,985–1-AP, Proteintech), IL-1β (41,610–1, Proteintech), IL-6 (bs-0782R, Bioss), and TNF-α (60,291–1-Ig, Proteintech). qRT-PCR RNA was extracted from samples using RNAiso

(16) The Role of Curcumin in Preventing Naturally Occurring Leiomyoma in the Galline ModelPharmaceuticals (Basel)December 21, 2024Kazim Sahin, Cemal Orhan, Mehmet Tuzcu, Nurhan Sahin, Ibrahim H. Ozercan, Nashwa Kabil, Omer Kucuk, Bulent Ozpolatp-P70S6K (bs-6370R), p-4E-BP1 (bs-3018R), Nrf2 (bs-1074R), HO-1 (bs-2075R), IL-1β (bs-0812R), IL-6 (bs-0782R), TNF-α (bs-0078R), ESR-α (bs-2098R) (Bioss, MA, USA, for all), PR (Abcam, ab191138), TGF-β1 α-SMA (Invitrogen,

(17) Boric Acid Protects the Uterus and Fallopian Tubes from Cyclophosphamide-Induced Toxicity in a Rat ModelPharmaceuticals (Basel)December 19, 2024Enes Karaman, Adem Yavuzmouse monoclonal with the clone number H1alpha 67; 1:100 dilution), and anti-IL-6 polyclonal antibody (bs-0782R, Bioss, Woburn, MA, USA; rabbit polyclonal anti-mouse IL-6 antibody, 1:250 dilution) were used. The

(18) Cardioprotective effect of <italic>Saussurea involucrata</italic> injection against Doxorubicin-induced cardiotoxicity by network pharmacology analysis and experimental verificationActa Biochimica et Biophysica SinicaDecember 5, 2024Ding Wang, Yu Jin, Mengyu Yang, Yajing Xue, Xiaotong Zhang, Yanli Guo, Xinzhi Li, Ketao Ma1:10,000; Proteintech), anti-phospho-NF-κB p65 (bs-5661R, 1:1000; Bioss, Beijing, China), and anti-IL6 (bs-0782R, 1:1000; Bioss). Experimental animals and treatments C57BL/6 male mice (8 weeks, 22–24 g) were obtained

(19) Mechanism of medical hemorrhoid gel in relieving pruritus ani via inhibiting the activation of JAK2/STAT3 pathwayFrontiers in MedicineNovember 13, 2024Zhongzhu Ai, Dongfeng Yuan, Jingyi Cai, Ruotong Dong, Wei Liu, Daonian ZhouAntibody,Lot,Producer,Dilutions TRPA1,A8568,"Abclonal (Wuhan, China)",1:500 β-actin,"66,009-1-Ig","Sanying (Wuhan, China)",1:30000 IL-6,BS-0782R,"Bioss (Beijing, China)",1:1000 5-HT1a,BS-1124R,"Bioss (Beijing, China)",1:1000 STAT3,"9,139",CST

(20) Nanocomposite Hydrogel for Real‐Time Wound Status Monitoring and Comprehensive TreatmentAdvanced ScienceNovember 1, 2024Huan Lei, Xueqing Yu, Daidi FanServicebio), CD206 (60143‐1, Proteintech), TNF‐α (bs‐10802R, Bioss), MMP‐9 (bs‐4593R, Bioss), IL‐6 (bs‐0782R, Bioss) and IL‐10 (bs‐6761R, Bioss). Immunofluorescence double staining: α‐SMA (bsm‐33188 M, Bioss)/CD31

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IL-6 Polyclonal Antibody

IL-6 Polyclonal Antibody from Bioss Inc.

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Bioss Inc.

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IL-6 Polyclonal Antibody from Bioss Inc.

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