The ATF3 Polyclonal Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to ATF3. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The ATF3 Polyclonal Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot.
Description
This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters