Adiponectin Polyclonal Antibody from Bioss Inc.

Supplier Page

Supplier Page from
Bioss Inc. for
Adiponectin Polyclonal Antibody

Bioss Inc.'s Adiponectin Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, Western Blot, and Other. The Adiponectin Polyclonal Antibody was generated using ADIPOQ as the antigen and it reacts with Homo Sapiens, Human, Mouse, Rat, Bovine, and Porcine.

Description

Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW