TREM2 Polyclonal Antibody bs-2723R from Bioss Inc.

Product Specs
ItemTREM2 Polyclonal Antibody
CompanyBioss Inc.
Price $375.00Supplier Page View Company Product Page
Catalog Numberbs-2723R
Molecular Weight25kDa
ImmunogenKLH conjugated peptide, human TREM2
Quantity100ul, 20uL
Conjugate/TagUnconjugated
ClonalityPolyclonal
Antibody TypePrimary Antibody
IsotypeIgG
ReactivityHuman, Mouse, Mouse, Pig
Format0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol
ApplicationsWB, IF, WB, ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC), IF
TargetTREM2
HostRabbit
Concentration1ug/ul
NCBI Gene AliasesTrem2c, Trem2a, PLOSL2, TREM-2, Trem2b
NCBI Full Gene Nametriggering receptor expressed on myeloid cells 2

Questions and Answers

How does the TREM2 antibody perform in studies related to neuroinflammation?

The TREM2 Polyclonal Antibody has been shown to inhibit inflammatory responses in mouse microglia by suppressing the PI3K/NF-κB signaling pathway. In a study, TREM2 overexpression significantly reduced the production of pro-inflammatory mediators and cytokines induced by lipopolysaccharide stimulation, suggesting its potential role in mitigating neuroinflammation ().

Can this antibody be used for immunohistochemical applications in human tissues?

Yes, the TREM2 Polyclonal Antibody has been utilized in immunohistochemical staining of postmortem Alzheimer's brain tissues, where it demonstrated specificity for neuronal but not microglial staining. This indicates its applicability in studying TREM2 expression in human tissues ().

What species can this antibody react with, and how has it been validated in research?

The TREM2 Polyclonal Antibody is reactive with several species, including humans, mice, rats, and porcine. It has been cited in multiple studies, including those investigating its role in macrophage polarization in pulmonary tuberculosis, where it was used to assess TREM2 expression in relation to M2 macrophage markers ().

What are some specific applications of this antibody in laboratory techniques?

The TREM2 Polyclonal Antibody is suitable for various applications, including Western blotting, ELISA, immunocytochemistry, immunofluorescence, and both frozen and paraffin-embedded tissue immunohistochemistry. Its versatility allows researchers to explore TREM2's role across different experimental setups ().

Bioss Inc.

300 Tradecenter Drive

Suite 4610

Woburn, MA 01801

United States

Phone: 800.501.7654 (Toll free)
Phone: +1.781.569.5821 (International)

Email: info@biossusa.com
orders@biossusa.com
support@biossusa.com
sales@biossusa.com

Company Profile

Website: www.biossusa.com

(1) Ketogenic interventions enhance REM sleep in females and support memory in aged ratsFront Aging NeurosciApril 10, 2026Arianna R. S. Lark, Fayaz A. Mir, Naqiya Ambareen, Fangyun Tian, Abigail Hardy Carpenter, Eliza A. Crowley, Bryton A. Toro, Channing E. Syme, Sema Aygar, Ahil Thendral, et al.Bioss BS-8551R), rabbit anti- triggering receptor expressed on myeloid cells 2 (TREM2) (1:200; Bioss BS-2723R), rabbit anti- NLR family pyrin domain containing 3 (NLRP3) (1:100; NBP2-12446), mouse anti-beta- III tubulin

(2) IL-12 ameliorates diabetic retinal neurodegeneration by activating microglial phagocytosis via the TREM2/DAP12 pathwayMolecular NeurobiologyJanuary 1, 2026Wanyi Fang, Shanshan Liu, Yifei Wu, Ting Chen, Xiaohe Lu, Hui Chen(1/200),Abcam,ab256805,59kDa Anti-Iba1 antibody,IHC (1/5000)ICC (1/200),Abcam,ab283319,17kDa Anti-TREM2,WB(1/1000),Bioss,bs-2723R,33kDa Anti-TYROBP,WB(1/1000),Bioss,bs-12630R,12kDa Anti-β-actin,WB(1/1000),Fude,FD0060,42kDa Anti-p-STAT4,WB(1/500),Santa cruz

(3) Triggering Receptor Expressed on Myeloid Cells 2 Mediates the Involvement of M2-Type Macrophages in Pulmonary Tuberculosis InfectionJournal of Inflammation ResearchMarch 27, 2024Xiaoqian Shang, Naifeisha Maimaiti, Jiahui Fan, Liang Wang, Yuanyuan Wang, Hu Sun, Jie Lv, Xiufeng Zhang, Jing Wang, Xiumin MaAntibody,Brand,Concentration Ag85B,"Bioss(bs-6460R), China",1:300 TREM2,"Bioss(bs-2723R), China",1:200 CD68,"Abcam(ab955), Britain",1:2000 INOS,"Bioss(bs-0162R), China",1:300 CD163,"Bioss(bs-2527R),

(4) The microglial innate immune receptor TREM2 participates in fear memory formation through excessive prelimbic cortical synaptic pruningFrontiers in immunologyJanuary 1, 2024Zhang LL, Cheng P, Chu YQ, Zhou ZM, Hua R, Zhang YM.PerCP/Cyanine5.5 anti-mouse Ly-6G,Mouse,"Biolegend, 127616",Flow Cytometry,1:200 APC-Cy7 anti-mouse TREM-2,Mouse,"Bioss, bs-2723r",Flow Cytometry,1:400 Experimental antibodies used in this article.

(5) A Population of M2 Macrophages Associated With Bone FormationFrontiers in immunologyJanuary 1, 2021Olmsted-Davis E, Mejia J, Salisbury E, Gugala Z, Davis AR.antibody (ab64693, Rabbit polyclonal; 1:200; Abcam, Cambridge, MA). Trem2 antibody (rabbit polyclonal, bs-2723r; 1:100, Bioss, Boston, MA). Tmem119 antibody (rabbit monoclonal, ab210405; 1:100, Abcam, Cambridge,

(6) TREM2 inhibits inflammatory responses in mouse microglia by suppressing the PI3K/NF-κB signalingCell biology internationalApril 1, 2019Li C, Zhao B, Lin C, Gong Z, An X.h and probed with primary antibodies at 4°C overnight. The primary antibodies included anti‐TREM2 (bs2723R, Bioss), anti‐GAPDH (AP0063, Bioworld, Minneapolis–Saint Paul, Minnesota, USA), anti‐pAKT(AF0016), anti‐p‐NF‐kBp65(AF2006,

(7) Vitamin D attenuates inflammation, fatty infiltration, and cartilage loss in the knee of hyperlipidemic microswineArthritis research & therapySeptember 13, 2016Rai V, Dietz NE, Dilisio MF, Radwan MM, Agrawal DK.antibodies, we used rabbit anti-TREM-1 (PAA213Po01; Cloud-Clone Corp., Houston, TX, USA), rabbit anti-TREM-2 (bs-2723R; Bioss Inc., Woburn, MA, USA), and mouse anti-CD14 (ab182032; Abcam, Cambridge, MA, USA) for macrophages,

(8) A survey of TREM2 antibodies reveals neuronal but not microglial staining in formalin-fixed paraffin-embedded postmortem Alzheimer's brain tissuesAlzheimer's research & therapyJanuary 1, 2013Satoh J, Kawana N, Yamamoto Y, Ishida T, Saito Y, Arima K.AF1828 (R&D Systems, Inc., Minneapolis, MN, USA), 2B5 (Novus Biologicals, Inc., Littleton, CO, USA), bs-2723R (Bioss, Woburn, MA, USA), PA5-18763 (Thermo Fisher Scientific Inc., Waltham, MA, USA), ab69405 (Abcam,

Be the First to Write a Review!

WB

TREM2 Polyclonal Antibody

WB

TREM2 Polyclonal Antibody from Bioss Inc.

Description

Questions and Answers

Bioss Inc.

Citations (8)

Reviews

TREM2 Polyclonal Antibody from Bioss Inc.

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map