ABCA1 Antibody PA1-16789 from Thermo Fisher Scientific

Product Specs
ItemABCA1 Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA1-16789
ClonalityPolyclonal
ReactivityCanine, Chicken, Equine, Hamster, Human, Mouse, Mustelid, Non-human primate, Porcine, Rabbit, Rat
Concentration1 mg/mL
IsotypeIgG
Antibody TypePrimary
StorageStore at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles
PurityAntigen affinity chromatography
Storage Temperature4° C, do not freeze
NCBI Gene AliasesCERP, HDLDT1, HDLCQTL13, ABC-1, ABC1, TGD, HPALP1, Abc1
ImmunogenPartial peptide sequence (within residues 1100-1300) of human ABCA1
ApplicationsWB, FCM, ICC, IHC-fr, IHC-p, IP, ChIP, GS/EMSA, ISH
NCBI Full Gene NameATP binding cassette subfamily A member 1, ATP-binding cassette, sub-family A (ABC1), member 1
TargetABCA1
FormatPBS with 0.02% sodium azide
Conjugate/TagUnconjugated
Quantity100 µL
HostRabbit

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(1) Shear Stress Regulates ABCA1-Dependent Membrane Cholesterol Content in Endothelial Cells Facilitating H2S-Dependent VasodilationMicrocirculationOctober 5, 2025Jacob R. Anderson, Nancy L. Kanagy, Laura V. Gonzalez Bosc, Jay S. Naikblocked with 5% non‐donkey serum (NDS) and treated with ABCA1 primary antibody (1:100) (Thermo Fisher, PA1‐16789) overnight at 4°C. Endothelial tubes were then blocked with 5% NDS for 1 h at 37°C and incubated with

(2) Intracellular accumulation of free cholesterol in macrophages triggers a PARP1 response to DNA damage and PARP1 impairs lipopolysaccharide-induced inflammatory responsePLoS OneMarch 5, 2025Kenneth K.Y. Ting, Hisham M. Ibrahim, Nitya Gulati, Yufeng Wang, Jonathan V. Rocheleau, Myron I. Cybulsky(CST#83732), anti-PARP1 (CST#9542), anti-pH2A.X (Ser139) (CST#2577), anti-H2A.X (CST#2595) and anti-ABCA1 (PA1-16789, ThermoFisher), followed by washing and incubation with HRP-conjugated anti-rabbit IgG (CST#7074) (22°C,

(3) Indole-3-Carboxaldehyde Inhibits Inflammatory Response and Lipid Accumulation in Macrophages Through the miR-1271-5p/HDAC9 PathwayJournal of cellular and molecular medicineDecember 1, 2024Luo W, Meng J, Yu XH, Zhang ZZ, Wang G, He J.

(4) Primate-specific 82-kDa choline acetyltransferase attenuates progression of Alzheimer's disease-like pathology in the APP(NL-G-F) knock-in mouse modelScientific reportsNovember 11, 2024AlQot HE, Rylett RJ.Anti-Arg1,Proteintech16001-1-AP,1:1000,– β-Actin,Millipore-Sigmaa5441,1:1000,– Rabbit Anti-ABCA1,Thermo Scientific PA1-16789,1:1000,– Rabbit Anti-Insulin degrading enzyme,Abcam ab32216,1:1000,– Rabbit Anti-LRP1,Abcam ab92544,1:1000,– Mouse

(5) TFEB controls sensitivity to chemotherapy and immuno-killing in non-small cell lung cancerJournal of experimental & clinical cancer research : CRAugust 7, 2024Akman M, Monteleone C, Doronzo G, Godel M, Napoli F, Merlini A, Campani V, Nele V, Balmas E, Chontorotzea T, et al.

(6) Expression of ATP-Binding Cassette Transporter A1 (ABCA1) in Eyelid Tissues and Meibomian Gland Epithelial CellsInvestigative ophthalmology & visual scienceMarch 5, 2024Zheng F, Su J, Wang J, Zhan Q, Su M, Ding S, Li W, Zhu YT, Guo P.(41400045); Gibco TrypLE Express Enzyme (1×), phenol red (12605010); Invitrogen ABCA1 Polyclonal Antibody (PA1-16789); Invitrogen PPAR gamma Monoclonal Antibody (K.242.9) (MA5-14889); Invitrogen F(ab′)2-Goat anti-Rabbit IgG (H+L) Cross-Adsorbed

(7) Single-cell transcriptomic heterogeneity between conduit and resistance mesenteric arteries in ratsPhysiological genomicsApril 1, 2023Anderson JR, Morin EE, Brayer KJ, Salbato S, Gonzalez Bosc LV, Kanagy NL, Naik JS.

(8) Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in miceNature metabolismDecember 1, 2022Paterson HAB, Yu S, Artigas N, Prado MA, Haberman N, Wang YF, Jobbins AM, Pahita E, Mokochinski J, Hall Z, et al.

(9) Targeting Cholesterol Homeostasis Improves Recovery in Experimental Optic NeuritisBiomoleculesOctober 7, 2022Godwin CR, Anders JJ, Cheng L, Elwood BW, Kardon RH, Gramlich OW.PSD95 (ab12093, abcam, Waltham, MA, USA), NG2 (ab275024, abcam), Olig2 (ab136253, abcam), or Abca1 (PA1 16789, Thermo Fisher) antibodies diluted 1:250 in blocking solution at 4 °C overnight. Slides were washed

(10) Givinostat-Liposomes: Anti-Tumor Effect on 2D and 3D Glioblastoma Models and PharmacokineticsCancersJune 16, 2022Taiarol L, Bigogno C, Sesana S, Kravicz M, Viale F, Pozzi E, Monza L, Carozzi VA, Meregalli C, Valtorta S, et al.from CST; β-Actin (MA5-15739, 1:5000), GAPDH (MA1-16757, 1:5000), VLDLR (MA5-24790, 1:1000), ABCA1 (PA1-16789, 1:500), LRP1 (MA1-27198, 1:500), and LDLR (PA5-22976, 1:1000) purchased from ThermoFisher. Membranes

(11) CTRP12 ameliorates atherosclerosis by promoting cholesterol efflux and inhibiting inflammatory response via the miR-155-5p/LXRα pathwayCell death & diseaseMarch 10, 2021Wang G, Chen JJ, Deng WY, Ren K, Yin SH, Yu XH.antibody against CTRP12 (PA5-46452, 1:500, ThermoFisher), rabbit polyclonal antibody against ABCA1 (PA1-16789, 1:800, ThermoFisher), rabbit polyclonal antibody against ABCG1 (GTX30598, 1:500, GeneTex, Irvine, CA,

(12) Liver X Receptor activation regulates genes involved in lipid homeostasis in developing chondrocytesOsteoarthritis and cartilage openMarch 1, 2020Sun MM, Beier F.overnight at 4 °C with primary antibodies against LXRα/β (sc-377260, Santa Cruz Biotechnology), Abca1 (PA1-16789, Thermo Fischer Scientific), or Srebp1 (PA1-337, Thermo Fischer Scientific). Secondary antibody incubation

(13) PMP22 Regulates Cholesterol Trafficking and ABCA1-Mediated Cholesterol EffluxThe Journal of neuroscience : the official journal of the Society for NeuroscienceJuly 3, 2019Zhou Y, Miles JR, Tavori H, Lin M, Khoshbouei H, Borchelt DR, Bazick H, Landreth GE, Lee S, Fazio S, et al.(IgM) Mouse Rat Rabbit Rabbit Rabbit ABCA1 ABCA1 ABCA1 ACC ApoE ApoE CD11b CD11b c-Myc Dystrophin GAPDH GS15 Laminin LAMP1 LC3 LDLR MAG P0 P62 p75 PHH3 PMP22 PMP22 PMP22 Rab8 Thy-1 Vinculin ␤-actin ␤-tubulin Novus Biologicals, NB400-105 (RRID: AB_10000630) Thermo Fisher Scientific, PA1-16789 (RRID: AB_2288917) Novus Biologicals, NB100-2068 (RRID: AB_10002789) Abcam, ab45174 (RRID: AB_867475) Millipore,

(14) ATP Binding Cassette Transporter A1 is Involved in Extracellular Secretion of Acetylated APE1/Ref-1International journal of molecular sciencesJune 28, 2019Lee YR, Joo HK, Lee EO, Cho HS, Choi S, Kim CS, Jeon BH.(cat.no. sc-58219, Santa Cruz Biotechnology, Santa Cruz, CA, USA) and polyclonal antibody (cat.no. PA1-16789, Invitrogen, Waltham, MA, USA) were used. Monoclonal (cat.no. NB100-116, Novus Biologicals, Littleton,

(15) The Liver X Receptor Is Upregulated in Monocyte-Derived Macrophages and Modulates Inflammatory Cytokines Based on LXRα PolymorphismMediators of inflammationJanuary 1, 2019Kim HA, Baek WY, Han MH, Jung JY, Suh CH.anti-TNF-α (1 : 1,000, ab183896, Abcam), anti-interferon-γ (IFN-γ; 1 : 1,000, EPR1108, Abcam), anti-ABCA1 (PA1-16789, Thermo scientiﬁc, Fremont, CA), and anticytoskeletal actin (1 : 10,000, A300-491A, Bethyl Laboratories, Montgomery,

(16) Calpains Released by T Lymphocytes Cleave TLR2 To Control IL-17 ExpressionJournal of immunology (Baltimore, Md. : 1950)January 1, 2016Perez J, Dansou B, Hervé R, Levi C, Tamouza H, Vandermeersch S, Demey-Thomas E, Haymann JP, Zafrani L, Klatzmann D, et al.Millipore). Membranes were blotted with specific primary Abs, including antiABCA1 rabbit polyclonal PA1-16789 (1/500; Thermo Fisher Scientific), anti-gp96 rabbit polyclonal 14491 (1/1000; Abcam), anti–IL-6R AF1830 (1/1000;

(17) Xanthine oxidoreductase is involved in macrophage foam cell formation and atherosclerosis developmentArteriosclerosis, thrombosis, and vascular biologyFebruary 1, 2012Kushiyama A, Okubo H, Sakoda H, Kikuchi T, Fujishiro M, Sato H, Kushiyama S, Iwashita M, Nishimura F, Fukushima T, et al.SR-B1, -B2, ABCG1 (Novus Biologicals, CO, #NB400 –101, 102, 132) and ABCA1 (Thermo Scientific, MA, #PA1-16789). Isolation and Purification of Primary Human Macrophages To obtain monocytes/macrophages, we isolated

(18) Binding of PDZ-RhoGEF to ATP-binding cassette transporter A1 (ABCA1) induces cholesterol efflux through RhoA activation and prevention of transporter degradationThe Journal of biological chemistryMay 21, 2010Okuhira K, Fitzgerald ML, Tamehiro N, Ohoka N, Suzuki K, Sawada J, Naito M, Nishimaki-Mogami T.

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ABCA1 Antibody

ABCA1 Antibody from Thermo Fisher Scientific

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ABCA1 Antibody from Thermo Fisher Scientific

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