Atg7 (D12B11) Rabbit mAb from Cell Signaling Technology

Yes, the Atg7 (D12B11) Rabbit mAb has been utilized in research that connects autophagy to apoptosis in cancer therapy. For instance, a study demonstrated that inhibiting autophagy can sensitize tumor cells to chemotherapy by increasing the expression of pro-apoptotic genes, highlighting the importance of Atg7 in these processes (fitzwalt2018).

The Atg7 antibody has been shown to work effectively in human keratinocytes, as evidenced by its use in a study examining the role of autophagy in UVB-induced inflammasome activation. The study indicated that gene silencing of Atg7 was part of the experimental design, confirming its relevance in this cellular context (hasegawa2024).

The Atg7 antibody has been employed in various studies to investigate the mechanisms of autophagy and its relationship with apoptosis. For example, it was used to assess the expression levels of autophagy-related proteins in the context of T-cell acute lymphoblastic leukemia, where it was found that autophagy plays a role in promoting apoptosis (qin2024).

The Atg7 (D12B11) Rabbit mAb is suitable for use in Western blotting and immunoprecipitation, as indicated by its application in multiple studies to analyze protein expression and interactions related to autophagy (kim2014, li2017).