TACE (D22H4) Rabbit mAb 6978S from Cell Signaling Technology

Product Specs
ItemTACE (D22H4) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number6978S
Quantity100 µl
ApplicationsW
ReactivityH
TargetTACE
HostRabbit
NCBI Gene AliasesADAM18, CD156B, CSVP, NISBD, NISBD1, TACE
ClonalityMonoclonal
NCBI Full Gene NameADAM metallopeptidase domain 17
Research AreaDevelopmental Biology
IsotypeIgG
CloneD22H4
Molecular Weight135

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Alpha-lipoic acid alleviates cognitive deficits in transgenic APP23/PS45 mice through a mitophagy-mediated increase in ADAM10 α-secretase cleavage of APPAlzheimer's research & therapyJuly 19, 2024Zhang J, Jiang Y, Dong X, Meng Z, Ji L, Kang Y, Liu M, Zhou W, Song W.from Abcam. Anti-sAPPα 6E10 (1:1000, SIG-39,320) was purchased from Biolegend. Anti-ADAM17 (1:2000, #6978), anti-BACE1(1:1000, #5606), anti-P62 (1:1000, #39,749), anti-LC3 (1:1000, #12,741), and anti-BNIP3L

(2) Influence of Race and High Laminar Shear Stress on TNFR1 Signaling in Endothelial CellsInternational Journal of Molecular SciencesSeptember 29, 2023Maitha Aldokhayyil, Dulce H. Gomez, Marc D. Cook, Andreas N. Kavazis, Michael D. Roberts, Thangiah Geetha, Michael D. Brownovernight at 4–8 °C. Primary antibodies used were as follows: TNFR1 (cat. no. 3736), TACE (cat. no. 6978), TRAF2 (cat. no. 4724), TRAF3 (cat. no. 4729), and TRAF5 (cat. no. 41658) from Cell Signaling Technology

(3) ALDH1A1 overexpression in melanoma cells promotes tumor angiogenesis by activating the IL‑8/Notch signaling cascadeInternational journal of molecular medicineJuly 1, 2022Ciccone V, Terzuoli E, Ristori E, Filippelli A, Ziche M, Morbidelli L, Donnini S.1:1,000, cat. no. 5313) and anti-A disintegrin and metalloproteinase-17 (ADAM17; rabbit, 1:1,000, cat. no. 6978) antibodies were from Cell Signaling Technology, Inc. Anti-β-actin antibody (mouse, 1:10,000, cat. no.

(4) Tumor necrosis factor is a necroptosis-associated alarminFrontiers in immunologyJanuary 1, 2022Pinci F, Gaidt MM, Jung C, Nagl D, Kuut G, Hornung V.(Millipore, Cat# AB19026, RRID : AB_2242320), anti-ADAM17 (D22H4) (Cell Signaling Technology, Cat# 6978, RRID : AB_1082838), anti-IκBα (L35A5) (Cell Signaling Technology, Cat# 4814, RRID : AB_390781), anti-phospho-IkBa

(5) Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient CellsCell reportsApril 7, 2020Drainas AP, Lambuta RA, Ivanova I, Serçin Ö, Sarropoulos I, Smith ML, Efthymiopoulos T, Raeder B, Stütz AM, Waszak SM, et al.,Cell Signaling Technology,Cat#5313; RRID:AB_2665555 Anti-TACE (D22H4) Rabbit monoclonal antibody,Cell Signaling Technology,Cat#6978; RRID:AB_10828385 "Anti-phospho-Histone H2A.X (Ser139) Mouse monoclonal antibody, clone JBW301","Merck KGaA

(6) GSK-3β Inhibitor Alsterpaullone Attenuates MPP+-Induced Cell Damage in a c-Myc-Dependent Manner in SH-SY5Y CellsFrontiers in Cellular NeuroscienceAugust 30, 2018Jiancai Wang, Yuqian Li, Li Gao, Fengqi Yan, Guodong Gao, Lihong Li

(7) STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH PathwayCancer researchOctober 15, 2017Jin L, Vu T, Yuan G, Datta PK.Cleaved Caspase 3 (#9661), Cleaved NOTCH1 (#4147), DLL1 (#2588), DLL4 (#2589), NUMB (#2756), TACE (#6978), JAG1 (#2620), JAG2 (#2210), HES1 (#11988), OCT4 (#2840), SNAIL (#3879), SLUG (#9585) and BMI1 (#5856)

(8) Regulated intramembrane proteolysis of the AXL receptor kinase generates an intracellular domain that localizes in the nucleus of cancer cellsFASEB journal : official publication of the Federation of American Societies for Experimental BiologyApril 1, 2017Lu Y, Wan J, Yang Z, Lei X, Niu Q, Jiang L, Passtoors WM, Zang A, Fraering PC, Wu F.ab1997; Abcam), LMNB1 (WB: 1:500, 12987-1-AP; Proteintech Group, Chicago, IL, USA), and TACE (WB:1:1000, 6978S; Cell Signaling Technologies, Beverly, MA, USA). Abs that targeted β-actin (WB: 1:2000, M20010), β-tubulin

(9) Influence of the HER receptor ligand system on sensitivity to cetuximab and trastuzumab in gastric cancer cell linesJournal of cancer research and clinical oncologyApril 1, 2017Kneissl J, Hartmann A, Pfarr N, Erlmeier F, Lorber T, Keller S, Zwingenberger G, Weichert W, Luber B.anti-HER4 (Cell Signaling, #4795), anti-pHER4 (Y1284) (Cell Signaling, #4757), anti-TACE (Cell Signaling, #6978), anti-β-actin (Sigma-Aldrich, #A1978), anti-α-tubulin (Sigma-Aldrich, #T9026), anti-rabbit IgG (Cell Signaling

(10) Identification of the IGF-1 processing product human Ec/rodent Eb peptide in various tissues: Evidence for its differential regulation after exercise-induced muscle damage in humansGrowth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research SocietyFebruary 1, 2017Vassilakos G, Philippou A, Koutsilieris M.

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(1)

12/7/2021Pefect TACE Antibody for WBDr. Christian OstaleckiTACE was transfected in HEK293T cells to measure its activation status when coexpressed with Nef and NAKC.

TACE (D22H4) Rabbit mAb

TACE (D22H4) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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TACE (D22H4) Rabbit mAb from Cell Signaling Technology

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