RAD18 Antibody (3H7)

Product Specs
ItemRAD18 Antibody (3H7) - Azide and BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberH00056852-M01
Quantity0.1 mg
ApplicationsELISA,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Knockdown Validated,Immunocytochemistry/ Immunofluorescence
Conjugate/TagUnconjugated
FormatIn 1x PBS, pH 7.4
PurityIgG purified
ReactivityHuman,Mouse,Rat
TargetRAD18
IsotypeIgG2b Kappa
Clone3H7
HostMouse
ImmunogenRAD18 (NP_064550, 332 a.a. ~ 430 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. EKEIDEIHSK YRKKHKSEFQ LLVDQARKGY KKIAGMSQKT VTITKEDEST EKLSSVCMGQ EDNMTSVTNH FSQSKLDSPE ELEPDREEDS SSCIDIQEV
NCBI Full Gene NameRAD18 E3 ubiquitin protein ligase
NCBI Gene AliasesRNF73
ClonalityMonoclonal
Research AreaCore ESC Like Genes, Stem Cell Markers, Zinc Finger
Antibody TypePrimary Antibodies
StorageAliquot and store at -20C or -80C. Avoid freeze-thaw cycles

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: RAD18 - RAD18 homolog (S. cerevisiae)

Sizes Available: 0.1 mg

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Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) RAD18 O-GlcNAcylation promotes translesion DNA synthesis and homologous recombination repairCell death & diseaseJanuary 1, 0001"Ma X, Fu H, Sun C, Wu W, Hou W, Zhou Z, Zheng H, Gong Y, Wu H, Qin J, et al."mouse anti-Flag (F1804, 1:1000) from Sigma (St Louis, MO), anti-RAD18 (ab17725, 1:1000) from Abcam and (H00056852-M01) from Novus Biologicals, anti-RAD18 pS434 from Dia-An Biotechnology, O-linked β-N-acetylglucosamine

(2) NBS1 recruits RAD18 via a RAD6-like domain and regulates Pol η-dependent translesion DNA synthesisMolecular cellJanuary 1, 0001"Yanagihara H, Kobayashi J, Tateishi S, Kato A, Matsuura S, Tauchi H, Yamada K, Takezawa J, Sugasawa K, Masutani C, et al."

(3) The ubiquitin specific protease USP34 promotes ubiquitin signaling at DNA double-strand breaksNucleic acids researchJanuary 1, 0001"Sy SM, Jiang J, O WS, Deng Y, Huen MS."

(4) USP1 Is Required for Replication Fork Protection in BRCA1-Deficient TumorsMolecular cellJanuary 1, 0001"Lim KS, Li H, Roberts EA, Gaudiano EF, Clairmont C, Sambel LA, Ponnienselvan K, Liu JC, Yang C, Kozono D, et al."

(5) Identification of DNA repair pathways that affect the survival of ovarian cancer cells treated with a poly(ADP-ribose) polymerase inhibitor in a novel drug combinationMolecular pharmacologyJanuary 1, 0001"Huehls AM, Wagner JM, Huntoon CJ, Karnitz LM."

(6) "RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress"OncogeneJanuary 1, 0001"Kanu N, Zhang T, Burrell RA, Chakraborty A, Cronshaw J, DaCosta C, Grönroos E, Pemberton HN, Anderton E, Gonzalez L, et al."Cruz), RPA (Sigma), WRNIP1 (N-17, Santa Cruz), PICH (Millipore), p-S139-H2AX (05-636, Upstate), RAD18 (H00056852-M01, Novus Biologicals), ATR (sc28901, Santa Cruz), Cyclin A (in-house antibody) and FITC/cy3/cy5-conjugated

(7) DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesisThe Journal of cell biologyJanuary 1, 0001"Zeman MK, Lin JR, Freire R, Cimprich KA."(mouse; sc56; Santa Cruz Biotechnology, Inc.), Rad18 (rabbit; 79763; Abcam; Fig. S2 A), Rad18 (mouse; H00056852-M01; Novus Biologicals), SHPRH (mouse; TA501443; OriGene), ubiquitin (mouse; BML-PW8810-0500; Enzo Life Sciences

(8) Tandem protein interaction modules organize the ubiquitin-dependent response to DNA double-strand breaksMolecular cellJanuary 1, 0001"Panier S, Ichijima Y, Fradet-Turcotte A, Leung CC, Kaustov L, Arrowsmith CH, Durocher D."

(9) Elevated expression of Rad18 regulates melanoma cell proliferationPigment cell & melanoma researchJanuary 1, 0001"Wong RP, Aguissa-Touré AH, Wani AA, Khosravi S, Martinka M, Martinka M, Li G."

(10) Phosphorylation of human INO80 is involved in DNA damage toleranceBiochemical and biophysical research communicationsJanuary 1, 0001"Kato D, Waki M, Umezawa M, Aoki Y, Utsugi T, Ohtsu M, Murakami Y."

(11) WRN participates in translesion synthesis pathway through interaction with NBS1Mechanisms of ageing and developmentJanuary 1, 0001"Kobayashi J, Okui M, Asaithamby A, Burma S, Chen BP, Tanimoto K, Matsuura S, Komatsu K, Chen DJ."

(12) Tumour suppressor ING1b maintains genomic stability upon replication stressNucleic acids researchJanuary 1, 0001"Wong RP, Lin H, Khosravi S, Piche B, Jafarnejad SM, Chen DW, Li G."

(13) HLTF's Ancient HIRAN Domain Binds 3' DNA Ends to Drive Replication Fork ReversalMolecular cellJanuary 1, 0001"Kile AC, Chavez DA, Bacal J, Eldirany S, Korzhnev DM, Bezsonova I, Eichman BF, Cimprich KA."

(14) Proliferating cell nuclear antigen (PCNA)-binding protein C1orf124 is a regulator of translesion synthesisThe Journal of biological chemistryJanuary 1, 0001"Ghosal G, Leung JW, Nair BC, Fong KW, Chen J."

(15) "Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links"Molecular and cellular biologyJanuary 1, 0001"Hicks JK, Chute CL, Paulsen MT, Ragland RL, Howlett NG, Guéranger Q, Glover TW, Canman CE."

(16) "RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress"OncogeneJanuary 1, 0001"Kanu N, Zhang T, Burrell RA, Chakraborty A, Cronshaw J, DaCosta C, Grönroos E, Pemberton HN, Anderton E, Gonzalez L, et al."Cruz), RPA (Sigma), WRNIP1 (N-17, Santa Cruz), PICH (Millipore), p-S139-H2AX (05-636, Upstate), RAD18 (H00056852-M01, Novus Biologicals), ATR (sc28901, Santa Cruz), Cyclin A (in-house antibody) and FITC/cy3/cy5-conjugated

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RAD18 Antibody (3H7) - Azide and BSA Free from Novus Biologicals, a Bio-Techne Brand

Specifications/Features

Novus Biologicals, a Bio-Techne Brand

Citations (16)

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RAD18 Antibody (3H7) - Azide and BSA Free from Novus Biologicals, a Bio-Techne Brand

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