Glucosylceramidase/GBA Antibody (2E2) - Azide and BSA Free H00002629-M01 from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemGlucosylceramidase/GBA Antibody (2E2) - Azide and BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $539.00Supplier Page View Company Product Page
Catalog NumberH00002629-M01
Quantity0.1 mg
ApplicationsELISA,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence
Conjugate/TagUnconjugated
FormatIn 1x PBS, pH 7.4
PurityIgG purified
ReactivityHuman,Plant
TargetGlucosylceramidase/GBA
IsotypeIgG2a Kappa
Clone2E2
HostMouse
ImmunogenGBA (NP_000148, 146 a.a. ~ 235 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. SYFSEEGIGY NIIRVPMASC DFSIRTYTYA DTPDDFQLHN FSLPEEDTKL KIPLIHRALQ LAQRPVSLLA SPWTSPTWLK TNGAVNGKGS
NCBI Full Gene Nameglucosylceramidase beta 1
NCBI Gene AliasesGCB, GLUC, GBA
ClonalityMonoclonal
Research AreaLipid and Metabolism
Antibody TypePrimary Antibodies
StorageAliquot and store at -20C or -80C. Avoid freeze-thaw cycles

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: GBA - glucosidase, beta; acid (includes glucosylceramidase)

Sizes Available: 0.1 mg

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Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) Late‐onset Krabbe disease presenting as spastic paraplegia – implications of GCase and CTSB/DAnnals of Clinical and Translational NeurologyJuly 1, 2024Rebecca Mächtel, Jan‐Philipp Dobert, Ute Hehr, Alexander Weiss, Matthias Kettwig, Lucia Laugwitz, Samuel Groeschel, Manuel Schmidt, Philipp Arnold, Martin Regensburger, et al.Fisher Scientific Inc./Invitrogen (#PA5‐19111)GBA monoclonal antibody (M01), clone 2E2 (mouse), Abnova (#H00002629‐M01)Human Cathepsin B antibody (goat), R&D Systems (#AF953)Human Cathepsin D antibody (goat), R&D Systems

(2) Production of recombinant human acid β-glucosidase with high mannose-type N-glycans in rice gnt1 mutant for potential treatment of Gaucher diseaseProtein expression and purificationJune 1, 2019Jung JW, Choi HY, Huy NX, Park H, Kim HH, Yang MS, Kang SH, Kim DI, Kim NS.

(3) Activation and Purification of ß-Glucocerebrosidase by Exploiting its Transporter LIMP-2 - Implications for Novel Treatment Strategies in Gaucher's and Parkinson's Disease"Advanced science (Weinheim, Baden-Wurttemberg, Germany)"January 1, 0001"Dobert JP, Bub S, Mächtel R, Januliene D, Steger L, Regensburger M, Wilfling S, Chen JX, Dejung M, Plötz S, et al."

(4) Pharmacological chaperones facilitate the post-ER transport of recombinant N370S mutant β-glucocerebrosidase in plant cells: evidence that N370S is a folding mutantMolecular genetics and metabolismJanuary 1, 0001"Babajani G, Tropak MB, Mahuran DJ, Kermode AR."

(5) Parkin-mediated ubiquitination of mutant glucocerebrosidase leads to competition with its substrates PARIS and ARTSOrphanet journal of rare diseasesJanuary 1, 0001"Bendikov-Bar I, Rapaport D, Larisch S, Horowitz M."

(6) Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's diseaseBrain : a journal of neurologyJanuary 1, 0001"Murphy KE, Gysbers AM, Abbott SK, Tayebi N, Kim WS, Sidransky E, Cooper A, Garner B, Halliday GM."

(7) Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretomeBloodJanuary 1, 0001"Campeau PM, Rafei M, Boivin MN, Sun Y, Grabowski GA, Galipeau J."

(8) Partial restoration of mutant enzyme homeostasis in three distinct lysosomal storage disease cell lines by altering calcium homeostasisPLoS biologyJanuary 1, 0001"Mu TW, Fowler DM, Kelly JW."University of Münster, Münster, Germany). Mouse monoclonal anti-GC 2E2 was from Novus Biologicals (#H00002629-M01). Antibodies directed against calnexin (#SPA-860), calreticulin (#SPA-601), Hsp40 (#SPA-400), Hsp70

(9) Characterization of the ERAD process of the L444P mutant glucocerebrosidase variant"Blood cells, molecules & diseases"January 1, 0001"Bendikov-Bar I, Ron I, Filocamo M, Horowitz M."

(10) Reduced glucocerebrosidase activity in monocytes from patients with Parkinson's diseaseScientific reportsJanuary 1, 0001"Atashrazm F, Hammond D, Perera G, Dobson-Stone C, Mueller N, Pickford R, Kim WS, Kwok JB, Lewis SJG, Halliday GM, et al."protein. We tested three GCase antibodies from three different companies (Abcam: ab175869, Abnova: H00002629-M01 and Novus: MAB7410) for both flow cytometry and immunoblot. The antibody from Abnova gave the correct

(11) Gaucher disease paradigm: from ERAD to comorbidityHuman mutationJanuary 1, 0001"Bendikov-Bar I, Horowitz M."

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Glucosylceramidase / GBA Antibody (2E2)

Glucosylceramidase/GBA Antibody (2E2) - Azide and BSA Free from Novus Biologicals, a Bio-Techne Brand

Specifications/Features

Novus Biologicals, a Bio-Techne Brand

Citations (11)

Reviews

Glucosylceramidase/GBA Antibody (2E2) - Azide and BSA Free from Novus Biologicals, a Bio-Techne Brand

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