The Anti-Mouse CD3 APC Antibody from MyBioSource.com is a Rat Monoclonal antibody. This antibody recognizes Mouse antigen. The Anti-Mouse CD3 APC Antibody has been shown to work in the following applications: Flow Cytometry.
Description
The 17A2 monoclonal antibody specifically reacts with the MouseT lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation. CD3 is expressed by thymocytes and mature lymphocytes, and contains gamma, delta, and epsilon subunits, involved in the assembly, trafficking, and surface expression of T-cell receptor complex.
The interaction between the T lymphocytes and the 17A2 antibody can be blocked by the 145-2C11 anti-CD3e antibody, demonstrating that the 17A2 antibody recognizes the CD3 epsilon chain