The SPINK5 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to serine peptidase inhibitor Kazal type 5, and SPINK5. This antibody recognizes Human antigen. The SPINK5 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The encoded preproprotein is proteolytically processed to generate multiple protein products, which may exhibit unique activities and specificities. These proteins may play a role in skin and hair morphogenesis, as well as anti-inflammatory and antimicrobial protection of mucous epithelia. Mutations in this gene may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. This gene is present in a gene cluster on chromosome 5. Alternative splicing results in multiple transcript variants