Ctip1 Antibody

Product Specs
ItemCtip1 Antibody - BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $479.00Supplier Page View Company Product Page
Catalog NumberNB600-261
ImmunogenA synthetic peptide which maps to a region between residues 775 and the C-terminus (residue 835) of human B-cell CLL/Lymphoma 11A using the numbering given in Swiss-Prot entry Q9H165 (GeneID 53335)
NCBI Gene AliasesDILOS, ZNF856, CTIP1, SMARCM1, HBFQTL5, EVI9
Concentration1.0 mg/ml
Conjugate/TagUnconjugated
Quantity100 ul
ReactivityHuman,Mouse
HostRabbit
TargetCtip1
ApplicationsChemotaxis,Flow Cytometry,Immunoprecipitation,Western Blot,Gel Supershift Assay,Chromatin Immunoprecipitation (ChIP)
FormatTris-Citrate/Phosphate (pH 7.0 - 8.0)
NCBI Full Gene NameBCL11 transcription factor A
ClonalityPolyclonal
PurityImmunogen affinity purified
Research AreaApoptosis, Cancer, Inhibitors Activators and Regulators, Transcription Factors and Regulators, Tumor Suppressors
IsotypeIgG
Antibody TypePrimary Antibodies
StorageStore at 4C. Do not freeze

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: NB600-261 is specific for human Bcl-11a protein.

Sizes Available: 100 ul

Add to Compare List

Questions and Answers

Can this antibody be used for flow cytometry applications?

Yes, the Ctip1 Antibody has been shown to work in flow cytometry applications, as evidenced by its use in a study where it was employed to analyze fixed and permeabilized cells for the expression of Ctip-1 alongside other transcription factors ().

Is this antibody effective for chromatin immunoprecipitation assays?

The Ctip1 Antibody has been utilized in chromatin immunoprecipitation assays, as indicated in a study where it was used to pull down BCL11A in the context of examining histone modifications and gene regulation ().

What species does this antibody react with?

The Ctip1 Antibody is reactive with human and mouse species, making it suitable for studies involving these organisms.

What role does BCL11A play in hematopoietic differentiation, and how might this antibody be relevant?

BCL11A is a critical transcription factor involved in hematopoietic lineage specification. The Ctip1 Antibody can be instrumental in studies investigating the regulatory mechanisms of BCL11A, particularly in the context of hematopoietic stem and progenitor cell differentiation, as it has been shown to suppress the expression of BCL11A in specific experimental models ().

Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) Regulation of BCL11A DNA binding and expression in human erythrocyte precursor HUDEP-2 cellsbioRxivFebruary 12, 2026Meigen Yu, Puspa Das, John R. Horton, Jujun Zhou, Jisun Lee, Tingting Hong, Yue Lu, Marcos R. Estecio, Polina A. Iakova, Abhinav K. Jain, et al.β-globin (37–8) (Santa Cruz #21757), γ-globin (51–7) (Santa Cruz #21756), BCL11A (Novus Biologicals #NB600–261), ZNF410 (Proteintech #14529–1-AP), IKZF1 (CST #14859) and actin (Sigma-Aldrich #A2228). Secondary antibodies

(2) Hydroxyurea reduces the levels of the fetal globin gene repressors ZBTB7A/LRF and BCL11A in erythroid cells in vitroJournal of Sickle Cell DiseaseNovember 7, 2024Gabriella E Martyn, Phillip A Doerfler, Yu Yao, Kate G R Quinlan, Mitchell J Weiss, Merlin Crossleyand Zbtb7a transcript levels. Additionally, nuclear extracts were prepared and analyzed for BCL11A (NB600-261, Novus Biologicals) and ZBTB7A (sc-33683, Santa Cruz Biotechnology Inc.) protein levels via Western blot

(3) Hydroxyurea differentially modulates activator and repressors of γ-globin gene in erythroblasts of responsive and non-responsive patients with sickle cell disease in correlation with Index of Hydroxyurea ResponsivenessHaematologicaJanuary 1, 0001"Zhu X, Hu T, Ho MH, Wang Y, Yu M, Patel N, Pi W, Choi JH, Xu H, Ganapathy V, et al."

(4) An in vitro model of human hematopoiesis identifies a regulatory role for the aryl hydrocarbon receptorBlood advancesJanuary 1, 0001"Khan DMIO, Karmaus PWF, Bach A, Crawford RB, Kaminski NE."(Invitrogen) for 20 minutes and incubated with relevant antibodies (antihuman Ctip-1 [Fluorophore PE, clone NB600-261; Novus Biologicals], antihuman IRF8 [Fluorophore APC, clone V3GYWCH; Thermo Fisher Scientific] and antihuman

(5) A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 siteBloodJanuary 1, 0001"Martyn GE, Wienert B, Kurita R, Nakamura Y, Quinlan KGR, Crossley M."

(6) The Coup-TFII orphan nuclear receptor is an activator of the γ-globin geneHaematologicaJanuary 1, 0001"Fugazza C, Barbarani G, Elangovan S, Marini MG, Giolitto S, Font-Monclus I, Marongiu MF, Manunza L, Strouboulis J, Cantù C, et al."

(7) A specific G9a inhibitor unveils BGLT3 lncRNA as a universal mediator of chemically induced fetal globin gene expressionNature communicationsJanuary 1, 0001"Takase S, Hiroyama T, Shirai F, Maemoto Y, Nakata A, Arata M, Matsuoka S, Sonoda T, Niwa H, Sato S, et al."39917; Goat anti-IgG (H + L) (1:100), Jackson Immunoresearch; anti-BCL11A (1:100), Novus Biologicals, NB600-261; anti-ZBTB7A (1:100), Thermo Fisher Scientific, eBioscience (13E9); anti-CHD3 (1:100), Novus Biologicals,

(8) Activation of γ-globin gene expression by GATA1 and NF-Y in hereditary persistence of fetal hemoglobinNature geneticsJanuary 1, 0001"Doerfler PA, Feng R, Li Y, Palmer LE, Porter SN, Bell HW, Crossley M, Pruett-Miller SM, Cheng Y, Weiss MJ."ng per lane; Santa Cruz Biotechnology: G-2 sc-17753), and BCL11A (1 μg per lane; Novus Biologicals: NB600–261) were used for supershift studies. For cold competition assays, annealed unlabeled probe was added to

(9) Transcriptional silencing of {gamma}-globin by BCL11A involves long-range interactions and cooperation with SOX6Genes & developmentJanuary 1, 0001"Xu J, Sankaran VG, Ni M, Menne TF, Puram RV, Kim W, Orkin SH."

(10) Bcl11a controls Flt3 expression in early hematopoietic progenitors and is required for pDC development in vivoPloS oneJanuary 1, 0001"Wu X, Satpathy AT, Kc W, Liu P, Murphy TL, Murphy KM."a Bioruptor (Diagenode), immunoprecipitation was performed with a rabbit polyclonal anti-Bcl11a antibody (NB600-261, Novus Biologicals) or control rabbit IgG, and qPCR analysis was carried out using SYBR Green-based

(11) Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A bindingNature geneticsJanuary 1, 0001"Martyn GE, Wienert B, Yang L, Shah M, Norton LJ, Burdach J, Kurita R, Nakamura Y, Pearson RCM, Funnell APW, et al."

Be the First to Write a Review!

Ctip1 Antibody

Ctip1 Antibody

Ctip1 Antibody

Ctip1 Antibody - BSA Free from Novus Biologicals, a Bio-Techne Brand

Specifications/Features

Questions and Answers

Novus Biologicals, a Bio-Techne Brand

Citations (11)

Reviews

Ctip1 Antibody - BSA Free from Novus Biologicals, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map