Fig 1: Inflammatory cell influx and ICAM-1/GAL-1 expression in the juxtamedullary region. (A–H) The ischaemia-reperfusion (IR) group showed intense neutrophil and macrophage infiltration in the juxtamedullary region (arrows; B and F, respectively) compared to the SHAM and DEXA- or GAL-1-treated groups. Details of two neutrophils in Figure B (inset). (I–P) The IR group exhibited enhanced expression of ICAM-1 and GAL-1 in the region with tubular necrosis (arrows) compared with all groups. Detail of the interstitial GAL-1 immunostaining in Figure N (inset). (A–D) Stain: haematoxylin-eosin. (E–P) Counterstain: haematoxylin. Bars: 20 µm (A–D); 50 µm (E–H); 100 µm (I–P). (Q–R) Quantitative analyses of neutrophils and macrophages. Data represent the mean ± SD of the cell number per mm2 or field. (S–T) Densitometric analysis of ICAM-1 and GAL-1 expression. Data (arbitrary units, a.u.) represent the mean ± SD of protein immunoreactivity. (N = 6/group). *p < 0.05, **p < 0.01 and ***p < 0.001, vs SHAM. +p < 0.05, ++p < 0.01 and +++p < 0.001 vs IR, one-way ANOVA.