Olig2 Anti-Human Rabbit IgG Affinity purify 18953 from IBL- America

Product Specs
ItemOlig2 Anti-Human Rabbit IgG Affinity purify
CompanyIBL- America
Price $596.00Supplier Page View Company Product Page
Catalog Number18953
ApplicationsIHC, WB
Quantity100 ug
ReactivityHuman
HostRabbit
IsotypeIgG
Regulatory StatusFor research use only, not for use in diagnostic procedures
ClonalityPolyclonal
FormatLyophilized product from 1% BSA in PBS containing 0.05% NaN3
PurityPurified with antigen peptide
ImmunogenSynthetic peptide in portion of C-terminus of Human Olig2
StorageLyophilized product, 5 years at 2 - 8 °C, Solution, 2 years at -20 °C

Questions and Answers

Can this antibody be used for immunohistochemistry in formalin-fixed tissues?

Yes, the Olig2 Anti-Human Rabbit IgG has been shown to be effective for immunohistochemistry in formalin-fixed paraffin-embedded tissues after microwave pretreatment, as demonstrated in studies such as and .

What is the optimal dilution for using this antibody in western blotting?

The antibody is recommended to be used at a concentration of approximately 2 µg/ml for western blotting, although this may need to be optimized based on specific experimental conditions.

Has this antibody been utilized in studies related to multiple sclerosis?

Yes, the Olig2 antibody has been referenced in studies investigating the origins of reactive astroglia in multiple sclerosis, highlighting its role in identifying oligodendrocyte lineage cells in demyelinated lesions, as seen in .

What specific cell types can this antibody help identify in neural tissue?

The Olig2 antibody is primarily used to identify oligodendrocyte precursor cells and mature oligodendrocytes, as indicated in various studies including and .

IBL- America

8201 Central Ave NE Suite P

Minneapolis, Minnesota 55432

United States

Phone: 888-523-1246
763-780-2988

Company Profile

Website: http://www.ibl-america.com/

(1) Pre-differentiation neurotoxicity of GenX exposure on hiPSC-derived cortical neuronsEnvironmental Science & TechnologyApril 7, 2026Shichen Wu, Junkai Xie, Xihui Zhao, Han Zhao, Oscar F. Sánchez, Serena Yu, Jean-Christophe Rochet, Jennifer L. Freeman, Chongli Yuan(Invitrogen, MA5–15738), anti-APP (Abcam, AB32136), anti-sAPPα (2B3) (IBL, 11088), anti-sAPPβ (IBL, 18953) and anti-APP, C-terminal (Sigma, AB8717). HRP-anti-mouse (Invitrogen, 31430) and HRP-anti-rabbit (Invitrogen,

(2) Copper deficiency impairs oligodendrocyte maturation and social behavior via mitophagy and mTOR suppression in ASDSci AdvApril 3, 2026Noriyoshi Usui, Miyuki Doi, Stefano Berto, Kiwamu Matsuoka, Rio Ishida, Hana Miyauchi, Yuuki Fujiwara, Koichiro Irie, Michihiro Toritsuka, Takahira Yamauchi, et al.Abcam), rabbit polyclonal anti-TBR1 (1:250, #ab31940, Abcam), rabbit polyclonal anti-OLIG2 (1:200; #18953, Immuno-Biological Laboratories Co. Ltd., Gunma, Japan), goat polyclonal anti-OLIG2 (1:300; #AF2418,

(3) The Ovine Brain as a Model for Human Neurodevelopment: Immunohistochemical Profiling of Brain Maturation Markers in Preterm LambsJ Comp NeurolMarch 24, 2026Yoann Rodriguez, Anne Leostic, Olivier Le Coz, Vincent Mauffré, Joanne Fortemps, Lucile Cavarec, Fabienne Constant, Marine Denis, Paul Berveiller, Aude Tessier, et al.and Sox10), we decided to target one of those transcription factors, namely Olig2 (IBL—America Cat# 18953, RRID:AB_2267671) known for oligodendrocytes differentiation, as our marker of choice. Regarding myelin,

(4) Extensive restoration of forelimb function in primates with spinal cord injury by neural stem cell transplantationNature BiotechnologyNovember 17, 2025Eleni Sinopoulou, Ephron S. Rosenzweig, John H. Brock, Hiromi Kumamaru, Ernesto A. Salegio, Michael J. Castle, Janet L. Weber, Rachele Wurr, Ryan Macon, Michelle W. Chow, et al.astrocytes (guinea pig, R&D, AF3075, 1:200) and Olig2 to label oligodendrocyte lineage (rabbit, IBL, 18953, 1:200). BDA was detected with Alexa-Fluor 594-conjugated or Alexa-Fluor 568-conjugated streptavidin

(5) Neurodevelopmental Changes in the Guinea Pig Brain Caused by Time-Limited Complete Vitamin C DeprivationNutrientsNovember 6, 2025Ivan Čapo, Ilija Andrijević, Nataša Čapo, Milan Popović, Ivan Milenković, Radomir Ratajac, Dejan Vranješ, Dragana Milutinović, Dragana Simin, Slobodan Sekulić(Tägerwilen, Switzerland)",-,1:5000 Anti-Olig2,polyclonal,Rabbit polyclonal,"IBL (Fujioka, Japan)",18953,1:100 Anti-TPPP,6C10,Mouse monoclonal,"Flow Labs UK (London, UK)",-,1:2000 Clonality, source and

(6) Reduced Accumulation Rate and Morphological Changes of Newly Generated Myelinating Oligodendrocytes in the Corpus Callosum of Aged MiceGliaNovember 1, 2025Sasikarn Looprasertkul, Reiji Yamazaki, Yasuyuki Osanai, Nobuhiko Ohnoor CC1, 1:100, IgG2b, OP80, Merck, Darmstadt, Germany), polyclonal rabbit anti‐human Olig2 (1:100, 18953, Immuno‐Biological Laboratories America, Minneapolis, USA), polyclonal rabbit anti‐contactin‐associated

(7) Type I collagen secreted in white matter lesions inhibits remyelination and functional recoveryCell Death DisApril 13, 2025Reiji Yamazaki, Morio Azuma, Yasuyuki Osanai, Tom Kouki, Takeshi Inagaki, Akiyoshi Kakita, Masaki Takao, Nobuhiko OhnoLSL), rabbit polyclonal anti-S100β (1:1 000; ab52642, Abcam), rabbit polyclonal anti-Olig2 (1:100; 18953, IBL America, Minneapolis, USA), rabbit polyclonal anti-GM130 (1:100; SAB5700801, Sigma-Aldrich), rabbit

(8) MicroRNAs Expression Profile in MN1-Altered AstroblastomaBiomedicinesJanuary 6, 2025Francesca Gianno, Evelina Miele, Claudia Sabato, Elisabetta Ferretti, Simone Minasi, Francesca Romana Buttarelli, Debora Salerno, Natalia Pediconi, Giuseppe Rubens Pascucci, Francesca Guerrieri, et al.30 min with GFAP (Novocastra-Leica Biosystems clone GA5, mouse monoclonal, 1:400 dilution), OLIG2 (18953-S IBL America, Minneapolis, MN, USA, rabbit polyclonal, 1:400 dilution), EMA (BOND-Leica Biosystem clone

(9) Potassium Release From the Habenular Astrocytes Induces Depressive‐Like Behaviors in MiceGliaNovember 29, 2024Hidenori Aizawa, Miho Matsumata, Laura Ayaka Noguera Oishi, Fumie Nishimura, Deepa Kamath Kasaragod, Xintong Yao, Wanqin Tan, Tomomi Aida, Kohichi Tanakaanti‐Sox2 (1:500; Cat# AB5603, RRID: AB_2286686, Sigma–Aldrich), polyclonal rabbit anti‐Olig2 (1:500; Cat# 18953, RRID: AB_1630817, Immuno‐Biological Laboratories Co. Ltd., Fujioka, Japan), monoclonal rabbit anti‐c‐Fos

(10) Rare Pediatric Cerebellar High-Grade Gliomas Mimic Medulloblastomas Histologically and Transcriptomically and Show p53 MutationsCancers (Basel)January 4, 2024Zhi-Feng Shi, Kay Ka-Wai Li, Anthony Pak-Yin Liu, Nellie Yuk-Fei Chung, Chit Chow, Hong Chen, Nim-Chi Amanda Kan, Xian-Lun Zhu, Danny Tat-Ming Chan, Ying Mao, et al.1:2500), Ki67 (Thermo Fisher, Waltham, MA, USA, SP6, 1:200), Olig2 (IBL-America, Minneapolis, MN, USA 18953, 1:120), Synaptophysin (Novocastra, Newcastle Upon Tyne, UK, NCL-L-SYNAP-299, 1:50), and p53 (Dako,

(11) Neuroprotective Effects of Genome-Edited Human iPS Cell-Derived Neural Stem/Progenitor Cells on Traumatic Brain InjuryStem CellsJune 15, 2023Ryotaro Imai, Ryota Tamura, Masahiro Yo, Mizuto Sato, Mariko Fukumura, Kento Takahara, Yoshitaka Kase, Hideyuki Okano, Masahiro TodaIgG; Chemicon; MAB377), anti-Olig2 (1:200, rabbit IgG; Immuno-Biological Laboratories, Fujioka, Japan; 18953), anti-Nestin (1:200, mouse IgG; Chemicon; MAB5326), anti-Nestin (1:100, mouse IgG1; Thermo Fisher Scientific;

(12) Transplanted human iPSC-derived vascular endothelial cells promote functional recovery by recruitment of regulatory T cells to ischemic white matter in the brainJournal of neuroinflammationJanuary 17, 2023Xu B, Shimauchi-Ohtaki H, Yoshimoto Y, Sadakata T, Ishizaki Y.Invitrogen, Cat# 13-5773-82) and a rabbit polyclonal antibody directed against Olig2 (1:200, IBL, Cat# 18953) at 4 °C overnight. For ED-1, STEM121, and Olig2 staining, after washing with PBS, the sections were

(13) COVID-19-associated monocytic encephalitis (CAME): histological and proteomic evidence from autopsySignal transduction and targeted therapyJanuary 6, 2023Zhang PP, He ZC, Yao XH, Tang R, Ma J, Luo T, Zhu C, Li TR, Liu X, Zhang D, et al.USA), SARS-CoV-2 spike protein (40150-T62-COV2, 1:1000 dilution, Sino Biological Inc., China), GFAP (18953-S, 1:400 dilution, IBL America, USA), IL-6 (ab6672, 1:250, Abcam), IL-4 (ab239508, 1:400 dilution, Abcam),

(14) Anti-inflammatory mechanisms and pharmacological actions of phycocyanobilin in a mouse model of experimental autoimmune encephalomyelitis: A therapeutic promise for multiple sclerosisFront ImmunolNovember 3, 2022Javier MarÃn-Prida, Nancy PavÃ³n-Fuentes, Nielsen Lagumersindez-Denis, Hanlet Camacho-RodrÃguez, Ana Margarita GarcÃa-Soca, RocÃo de la Caridad Sarduy-ChÃ¡vez, Ã‰rica Leandro Marciano Vieira, Juliana Carvalho-Tavares, Viviana FalcÃ³n-Cama, Julio RaÃºl FernÃ¡ndez-MassÃ³, et al.protein (TPPP/p25) (1:500, Cat. No. 92305, Abcam, Cambridge, UK) and an anti-Olig2 (1:300, Cat. No. 18953, IBL, Hamburg, Germany) were used for detecting mature OD and OPC, respectively. A streptavidin-biotin

(15) ATRT–SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significanceActa NeuropathologicaJune 1, 2022Aniello Federico et al.validation yielded comparable results. Immunohistochemical staining for GFAP (#GA524, Agilent), OLIG2 (#18953, Immuno-Biological Laboratories, Inc.), and synaptophysin (#M7315, Agilent), was performed using the

(16) Treatment of adult metachromatic leukodystrophy model mice using intrathecal administration of type 9 AAV vector encoding arylsulfatase AScientific ReportsDecember 1, 2021Noriko Miyake, Koichi Miyake, Atsushi Sakai, Motoko Yamamoto, Hidenori Suzuki, Takashi ShimadaSigma-Aldrich), rabbit anti-Iba1 (019-19741; 1:500, FUJIFILM, Osaka, Japan), rabbit anti-human Olig2 (18953; 1:200, IBL, Gunma, Japan), and rabbit anti-GFP (A21311; 1:1000, Invitrogen, Life Technologies Corp.,

(17) Impact of Fetal Growth Restriction on the Neonatal Microglial Proteome in the RatNutrientsOctober 22, 2021Manuela Zinni et al.MO, USA), rabbit anti-NeuN (1:500, ABN78, Millipore, Burlington, MA, USA), rabbit anti-Olig2 (1:200, 18953, Immuno-Biological Laboratories, Minneapolis, MN, USA), and DAPI (1:10,000). The following day, cells

(18) The presence of TIM‐3 positive cells in WHO grade III and IV astrocytic gliomas correlates with isocitrate dehydrogenase mutation statusBrain PathologyMay 1, 2021Mia D. Sørensen, Ole Nielsen, Guido Reifenberger, Bjarne W. Kristensen(#760‐4307) 8 min Primary Ab #1,"Anti‐OLIG2 rabbit polyclonal Ab (Immuno‐Biological Laboratories, #18953) 1:200, 32 min 36°C" Detection,Anti‐Rabbit‐HQ (#760‐4815) 20 min + anti‐HQ‐HRP (#760‐4820) 20 min Amplification,No Chromogen,ChromoMap

(19) Acute motor deficit and subsequent remyelination‐associated recovery following internal capsule demyelination in miceJournal of NeurochemistryMarch 1, 2021Reiji Yamazaki, Nobuhiko Ohno, Jeffrey K. Huang(RRID:AB_477272, Cat# N4142, 1:200; Sigma‐Aldrich), rabbit polyclonal anti‐Olig2 antibody (RRID:AB_1630817, Cat# 18953, 1:100; IBL America), rabbit polyclonal anti‐Type I collagen (RRID:AB_1962715, Cat# LB‐1102, 1:1,000;

(20) Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19Nature neuroscienceFebruary 1, 2021Meinhardt J, Radke J, Dittmayer C, Franz J, Thomas C, Mothes R, Laue M, Schneider J, Brünink S, Greuel S, et al.rabbit polyclonal anti-ACE2 (Proteintech, 21115-1-AP; 1:3,000) and rabbit polyclonal anti-OLIG2 (IBL, 18953; 1:150, pretreatment Tris-EDTA + microwave). Briefly, primary antibodies were applied and developed

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Olig2 Anti-Human Rabbit IgG Affinity purify from IBL- America

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Olig2 Anti-Human Rabbit IgG Affinity purify from IBL- America

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