Fig 1: a Flow cytometry immunophenotyping of CD3+/CD4+, CD3+/CD8+, NK1.1+/CD3−,NK1.1+/CD3+ and macrophage population of splenocyte; b serum IL-1β, IL-10, IL-2 and IFN-γ cytokines level; c cytotoxicity of splenocytes against Yac-1 cells at ratio of 2 to 1 and 5 to 1 foruntreated (UT), 0.08 mL/kg BW pineapple treated mice (PL) and 2 mL/kg BW pineapple treated mice (PH) after 28 days of treatment. Note: The data presented were representative of biological replicates obtaining from three independent experiments ± SD (n = 3). Significant values were calculated against UT group (*P < 0.05)