GPX4 Antibody PA5-102521 from Thermo Fisher Scientific

Product Specs
ItemGPX4 Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA5-102521
Quantity100 µL
ApplicationsImmunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration1 mg/mL
Conjugate/TagUnconjugated
FormatPBS with 50% glycerol and 0.02% sodium azide; pH 7.4
PurityAffinity chromatography
ReactivityHuman, Mouse, Rat
TargetGPX4
IsotypeIgG
HostRabbit
Antibody TypePrimary
ImmunogenA synthesized peptide derived from human GPX4(Accession P36969), corresponding to amino acid residues I170-F197
NCBI Full Gene Nameglutathione peroxidase 4
NCBI Gene AliasesmtPHGPx, MCSP, gpx-4, PHGPx, Gshpx-4, snPHGPx, SMDS, GSHPx-4, GPx-4, snGPx, Phgpx, snGpx
ClonalityPolyclonal
Storage-20°C

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Waltham, MA 02451

United States

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Website: www.thermofisher.com

(1) Continuous Pyruvate Supplementation Enhances Neuroprotective Resilience Against Kainate-Induced Status Epilepticus Through Metabolic PreconditioningBiomoleculesMay 29, 2026Yong Jae Cho, Soo Jin Lee, Yuna Kim, Yeeun Kim, Seog-Young Kim, Kyunggon Kim, Dong-Cheol Woo, Hyun Ju Yoo, Joo-Yong LeeThermo Fisher Scientific; PA5-99486; 1:1000), anti-glutathione peroxidase-4 (GPX4: Invitrogen™, Thermo Fisher Scientific; PA5-102521; 1:1000), anti-heat shock protein 70 (HSP70; Enzo Biochem, Farmingdale, NY, USA; ADI-SPA-810; ADI-SPA-810;

(2) Fenofibrate mitigates microglial activation by reprogramming lipid metabolism and inhibiting ferroptosisMolecular and Cellular BiochemistryApril 28, 2026Ahmet Taskesen, Ceyhan Hacioglu, Sibel Tuncer, Guven Kilic, Cengiz Tuncertargeting ACSL4 (1:200 dilution, Thermo Fisher, PA5-27137) and GPX4 (1:500 dilution, Thermo Fisher, PA5-102521). Following extensive washing to remove unbound antibodies, fluorophore-labeled secondary antibodies

(3) Protective effects of morin and propolis against cytarabine-induced neurotoxicity: a multi-biomarker approachOpen Life SciencesFebruary 20, 2026Hakan Bağ, Seval Yılmaz, Songül Çeribaşı8-OHdG (Bioss Company, Cas No: bs-1278R), and Glutathione Peroxidase 4 (GPX4) (Invitrogen, Cas No: PA5-102521) primary antibodies at 4 °C overnight. The sections were washed again in PBS, and biotinylated secondary

(4) Polysaccharides from Huaier induce autophagy-dependent ferroptosis to inhibit breast cancer stem cells in triple-negative breast cancerCancer Cell InternationalDecember 10, 2025Linxi Zhou, Ziwei Wu, Kefei Luo, Hong Zheng, Yuan Tian, Qinwen Pan, Wenting Yan, Jun Jiang, Lingmi Hou, Minghao WangµL/test) antibodies were obtained from BioLegend (USA). BODIPY™ 581/591 C11 (D3861, 5 µM/test), GPX4 (PA5-102521), and ASM antibodies (PA5-77047) were sourced from Thermo Fisher (USA). The following antibodies were

(5) Mechanism of Artemisia argyi Levl.et Vant. aqueous extract in alleviating dextran sulfate sodium-induced ulcerative colitisSci RepOctober 21, 2025Lan Shi, Jiahao Wu, Xianmo Wang, Xiaowan YangChina, 1:100), TRAF6 (PA5-29622, Invitrogen, 1:100), PTGS2 (PA5-17614, Invitrogen, 1:200), and GPX4 (PA5-102521, Invitrogen, 1:200) at 4℃ and incubated with goat anti-rabbit IgG fluorescent secondary antibody (A-11008,

(6) Early pathological changes in the liver and kidney of non-obese diabetic (NOD) mice: involvement of iron accumulation and ferroptosisFront Endocrinol (Lausanne)October 2, 2025Ana Stancic, Milica Markelic, Nevena Savic, Ksenija Velickovic, Vesna Martinovic, Andjelija Gudelj, Danica Velickovic, Ilijana Grigorov, Vesna Otasevicab190775, Abcam), xCT (goat anti-xCT, 1:100, sc-79360, Santa Cruz Biotechnology), GPX4 (rabbit anti-GPX4, PA5-102521, Thermo Fisher Scientific, USA), nuclear factor erythroid 2-related factor 2 (rabbit anti-Nrf2, 1:60,

(7) Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinomaMolecular OncologySeptember 1, 2025Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, et al.with the following antibodies: GPX4 (Invitrogen‐Thermo Fisher Scientific, Waltham, MA, USA, rabbit, #PA5‐102521, 1 : 300), Carbonic Anhydrase IX (CA IX) EP161 (Cell Marque, Rocklin, CA, USA, rabbit, #379R‐14, 1 : 100

(8) Knockdown of Gfi1 increases BMSCs exosomal miR-150-3p to inhibit osteoblast ferroptosis in steroid-induced osteonecrosis of the femoral head through BTRC/Nrf2 axisEndocrine journalFebruary 3, 2025Zheng L, Zhang C, Liao L, Hai Z, Luo X, Xiao H.followed by blocking with goat serum for 30 min. The cells were then incubated with anti-GPX4 antibody (PA5-102521, 1:200, Invitrogen) at 4°C overnight. Subsequently, the FITC-conjugated goat anti-rabbit IgG secondary

(9) METTL14-mediated N6-methyladenosine modification induces the ferroptosis of hypoxia/reoxygenation-induced cardiomyocytesJournal of cardiothoracic surgeryApril 25, 2024Zhao C, Li J.

(10) Borax induces ferroptosis of glioblastoma by targeting HSPA5/NRF2/GPx4/GSH pathwaysJournal of cellular and molecular medicineApril 1, 2024Tuncer C, Hacioglu C.μg/mL; PA1‐014A; Invitrogen), NRF2 (dilution 1:2000; PA5‐88084; Invitrogen), GPx4 (dilution 1:1000; PA5‐102521; Invitrogen) and cleaved caspase‐3 (dilution 1:1000; Cat No. 9661; Cell Signaling). Following the primary

(11) Isatin improves oligoasthenospermia caused by busulfan by regulating GSH/GPX4 axis to inhibit ferroptosisFrontiers in pharmacologyJanuary 1, 2024Wang C, Wang W, Dong J, Li X, Ye T, Zeng F, Jiang M, Shi J, Wang X, Zhang L.(BL523A, Biosharp, Anhui, China) was utilized for visualization. Primary antibodies used include: GPX4 (PA5-102521, Invitrogen, 1:1,000), KEAP1 (WL03285, Wanleibio, 1:1,500), TFR1 (A21622, ABclonal, 1:100), FTH1 (A19544,

(12) Overburdened ferroptotic stress impairs tooth morphogenesiseLifeNovember 22, 2023Wang H, Wang X, Huang L, Wang C, Yu F, Ye L.cooled to room temperature. Sections were incubated overnight at 4°C with Gpx4 (1:200, Invitrogen, PA5-102521) in 2% bovine serum albumin (BSA)/phosphate-buffered saline (PBS), pH 7.4. Negative control sections

(13) Inhibitory Effects of Esculetin on Liver Cancer Through Triggering NCOA4 Pathway-Mediation Ferritinophagy in vivo and in vitroJournal of hepatocellular carcinomaJanuary 1, 2023Xiu Z, Li Y, Fang J, Han J, Li S, Li Y, Yang X, Song G, Li Y, Jin N, et al.and LC3II (14600-1-AP) were purchased from proteintech. HO-1 (86806, CST), FTH1 (4393, CST), Gpx4 (PA5-102521, Invitrogen), NCOA4 (HC071-1F11, Sigma-Aldrich). Esculetin, Cisplatin and Sorafenib (MCE, USA), T-AOC

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GPX4 Antibody

GPX4 Antibody from Thermo Fisher Scientific

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GPX4 Antibody from Thermo Fisher Scientific

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