NeuroD1 Antibody AF2746 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemNeuroD1 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF2746
NCBI Gene AliasesNEUROD, T2D, BHF-1, MODY6, BETA2, bHLHa3
ApplicationsFlow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry
Quantity100 ug (also 25 ug)
TargetNeuroD1
HostGoat
ReactivityHuman,Mouse,Rat,Transgenic Mouse,Xenograft
IsotypeIgG
Conjugate/TagUnconjugated
NCBI Full Gene Nameneuronal differentiation 1
ClonalityPolyclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ImmunogenE. coli-derived recombinant human NeuroD1, Ser154-Asp356, Accession # Q13562
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects NeuroD1 in direct ELISAs and Western blots. In these formats, approximately 5% cross-reactivity with recombinant human NeuroD2 is observed.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Exendin-4 enhances insulin-positive phenotype of human pluripotent stem cell-derived β cells during transplantationMolecular TherapyOctober 1, 2025Kelly M. Crumley, Elizabeth J. Bealer, Anne C. Lietzke, Scott A. Soleimanpour, Lonnie D. Sheaglucagon (Sigma, cat. G2654), human somatostatin (Dako, cat. A0566), and human NEUROD1 (R&D Systems, cat. AF2746) primaries, followed by AlexaFluor donkey anti-mouse 488 nm (Invitrogen, cat. A21202), AlexaFluor donkey

(2) Quiescent horizontal basal stem cells act as a niche for olfactory neurogenesis in a mouse 3D organoid modelCell Reports MethodsJune 16, 2025Juliana Gutschow Gameiro, Constantin A. Hintschich, Agnès Dekeyser, Valérie Hox, James E. Schwob, Eric H. Holbrook, Marco Aurélio Fornazieri, Brian LinAntibody (Btjce),Invitrogen,14-9811-82; RRID:AB_11219471 Human/Mouse NeuroD1 Antibody,R&D systems,AF2746; RRID:AB_2149217 Purified anti-Keratin 5 Polyclonal Chicken Antibody,Biolegend,905904; RRID:AB_2721743 Mouse

(3) 3D model of mouse embryonic pancreas and endocrine compartment using stem cell-derived mesoderm and pancreatic progenitorsiScienceJune 21, 2024Shlomit Edri, Vardit Rosenthal, Or Ginsburg, Abigail Newman Frisch, Christophe E. Pierreux, Nadav Sharon, Shulamit LevenbergAB_259852 Guinea pig anti-insulin; 1:200,DAKO,A0564; RRID: AB_10013624 Goat anti-neuroD1; 1:300,R&D Systems,AF2746; RRID: AB_2149217 Rabbit anti-cytokeretin19 (CK19); 1:500,Abcam,ab133496; RRID: AB_11155282 Rabbit

(4) CD20 is a mammalian odorant receptor expressed in a subset of olfactory sensory neurons that mediates innate avoidance of predatorsbioRxiv : the preprint server for biologyAugust 10, 2023Jiang HC, Park SJ, Wang IH, Bear DM, Nowlan A, Greer PL.

(5) Differentiation of stem cell-derived pancreatic progenitors into insulin-secreting islet clusters in a multiwell-based static 3D culture systemCell Rep MethodsMay 22, 2023Liang S, Zhao J, Baker RK, Tran E, Zhan L, Kieffer TJ.monoclonal anti-NKX6.1,DSHB,Cat# F55A12;RRID: AB_532379 Goat polyclonal anti-NEUROD1,R&D Systems,Cat# AF2746;RRID: AB_2149217 Guinea pig polyclonal anti-insulin,Abcam,Cat# ab195956;RRID: AB_2877638 Mouse monoclonal

(6) Molecular Evidence for Olfactory Neuroblastoma as a Tumor of Malignant Globose Basal CellsModern PathologyMay 1, 2023Matthew J. Zunitch, Adam S. Fisch, Brian Lin, Camila M. Barrios-Camacho, William C. Faquin, Yaw Tachie-Baffour, Jonathan D. Louie, Woochan Jang, William T. Curry, Stacey T. Gray, et al.immunohistochemistry Target,Source,Species,Antigen Retrieval,Dilution,Amplification NEUROD1,R&D Systems #AF2746,Goat polyclonal,EDTA buffer (pH 9.0),1 to 100,"SA-HRP, DAB" EZH2,Cell Signaling Technology #5246,Rabbit

(7) Notch signaling determines cell-fate specification of the two main types of vomeronasal neurons of rodentsDevelopment (Cambridge, England)July 1, 2022Katreddi RR, Taroc EZM, Hicks SM, Lin JM, Liu S, Xiang M, Forni PE.Abcam), *mouse anti-NeuroD1 (1:100, sc-46684, Santa Cruz Biotechnology), *goat anti-NeuroD1 (1:500, AF2746, R&D Systems), *rabbit anti-Notch1 (1:50, D1E11, Cell Signaling Technology), goat anti-Dll4 (*with antigen

(8) Progenitor cells from brown adipose tissue undergo neurogenic differentiationScientific reportsApril 4, 2022Jumabay M, Zhang L, Yao J, Boström KI.(Santa Cruz Biotechnology, Cat. No. sc-15368 (H-170), dilution 1:200), goat anti-NeuroD (R&D Systems, Cat. No. AF2746, dilution 1:200), and mouse anti-Neurofilament (NFL) (Thermo Fisher Scientific, Cat. No. 13–0400, dilution

(9) Chemical combinations potentiate human pluripotent stem cell-derived 3D pancreatic progenitor clusters toward functional β cellsNature communicationsJune 7, 2021Liu H, Li R, Liao HK, Min Z, Wang C, Yu Y, Shi L, Dan J, Hayek A, Martinez Martinez L, et al.

(10) Reactive, Adult Neurogenesis From Increased Neural Progenitor Cell Proliferation Following Alcohol Dependence in Female RatsFrontiers in neuroscienceJanuary 1, 2021Nawarawong NN, Thompson KR, Guerin SP, Anasooya Shaji C, Peng H, Nixon K.no.,Conc.,Time in primary (h),Secondary antibody (source) DAB,DAB,DAB,DAB,DAB Goat anti-NeuroD1,R&D systems; AF2746,1:400,24,Biotinylated rabbit anti-goat (Vector) Goat anti-Prox1,R&D systems; AF2727,1:200,24,Biotinylated

(11) Targeting the cytoskeleton to direct pancreatic differentiation of human pluripotent stem cellsNature biotechnologyApril 1, 2020Hogrebe NJ, Augsornworawat P, Maxwell KG, Velazco-Cruz L, Millman JR.anti-glucagon (ABCAM, ab82270), mouse anti-NKX2–2 (DSHB, 74.5A5-S), goat anti-NEUROD1 (R&D Systems, AF2746), mouse anti-ISL1 (DSHB, 40.2d6-s), rabbit anti-CHGA (ABCAM, ab15160), rabbit anti-MAFB (MilliporeSigma,

(12) HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cellsNature immunologyMarch 1, 2020Wang Y, Lifshitz L, Gellatly K, Vinton CL, Busman-Sahay K, McCauley S, Vangala P, Kim K, Derr A, Jaiswal S, et al.

(13) Deletion of Btg1 Induces Prmt1-Dependent Apoptosis and Increased Stemness in Shh-Type Medulloblastoma Cells Without Affecting Tumor FrequencyFrontiers in oncologyJanuary 1, 2020Ceccarelli M, D'Andrea G, Micheli L, Tirone F.USA; sc-19648; 1:100); goat polyclonal antibody against NeuroD1 (R&D Systems, Minneapolis, MN, USA; AF2746; 1:200). To visualize the antigens, the samples were reacted with the appropriate secondary antibodies,

(14) Wnt Signaling Separates the Progenitor and Endocrine Compartments during Pancreas DevelopmentCell reportsMay 21, 2019Sharon N, Vanderhooft J, Straubhaar J, Mueller J, Chawla R, Zhou Q, Engquist EN, Trapnell C, Gifford DK, Melton DA.Glucagon,Santa Cruz Biotechnology,Cat#sc-514592; RRID: AB_2629431 Goat anti Neurod1,R&D systems,Cat#AF2746; RRID: AB_2149217 Sheep anti Neurogenin3,R&D systems,Cat#AF3444; RRID: AB_2149527 Mouse anti Nkx6.1,DSHB,Cat#F55A12;

(15) A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic IsletsCellFebruary 7, 2019Sharon N, Chawla R, Mueller J, Vanderhooft J, Whitehorn LJ, Rosenthal B, Gürtler M, Estanboulieh RR, Shvartsman D, Gifford DK, et al.Muc1,NeoMarkers,Cat#HM-1630-P1 Rabbit anti Ncad,Invitrogen,Cat#MA5–16324 Goat anti Neurod1,R&D systems,Cat#AF2746 Rabbit anti Neurogenin3,EMD Millipore,Cat#Ab10535 Mouse anti Nkx6.1,DSHB,Cat#F55A12 Rabbit anti proglucagon,Cell

(16) The Neuroregenerative Capacity of Olfactory Stem Cells Is Not Limitless: Implications for AgingThe Journal of neuroscience : the official journal of the Society for NeuroscienceAugust 1, 2018Child KM, Herrick DB, Schwob JE, Holbrook EH, Jang W.9661S Abcam EP890Y Wako 019-19741 BD Biosciences 556003 LSBio LS-C112469 Invitrogen OSR00212W R&D Systems AF2746 Santa Cruz Biotechnology sc-49070 Santa Cruz Biotechnology sc-365818 ATCC Proteintech14730-1-AP eBioscience

(17) Tis21-gene therapy inhibits medulloblastoma growth in a murine allograft modelPloS oneJanuary 1, 2018Presutti D, Ceccarelli M, Micheli L, Papoff G, Santini S, Samperna S, Lalli C, Zentilin L, Ruberti G, Tirone F.BU1/75; MCA2060; 1:300) was from AbD Serotec (Raleigh, NC, USA); NeuroD1 goat polyclonal antibody (AF2746; 1:200) was from R&D Systems (Minneapolis, MN, USA); NeuN mouse monoclonal IgG1 antibody (clone A60;

(18) Terminal Differentiation of Adult Hippocampal Progenitor Cells Is a Step Functionally Dissociable from Proliferation and Is Controlled by Tis21, Id3 and NeuroD2Frontiers in cellular neuroscienceJanuary 1, 2017Micheli L, Ceccarelli M, Gioia R, D'Andrea G, Farioli-Vecchioli S, Costanzi M, Saraulli D, Cestari V, Tirone F.NeuroD1 antibody used in cell cycle studies was a goat polyclonal (R&D Systems, Minneapolis, MN, USA; AF2746; 1:200). Secondary antibodies used to visualize the antigen were all, with the exception of the secondary

(19) Influence of in vitro and in vivo oxygen modulation on β cell differentiation from human embryonic stem cellsStem cells translational medicineMarch 1, 2014Cechin S, Alvarez-Cubela S, Giraldo JA, Molano RD, Villate S, Ricordi C, Pileggi A, Inverardi L, Fraker CA, Domínguez-Bendala J.

(20) Tis21 knock-out enhances the frequency of medulloblastoma in Patched1 heterozygous mice by inhibiting the Cxcl3-dependent migration of cerebellar neuronsThe Journal of neuroscience : the official journal of the Society for NeuroscienceOctober 31, 2012Farioli-Vecchioli S, Cinà I, Ceccarelli M, Micheli L, Leonardi L, Ciotti MT, De Bardi M, Di Rocco C, Pallini R, Cavallaro S, et al.(Millipore Bioscience Research Reagents; MAB377; 1:100), a goat polyclonal antibody against NeuroD1 (R&D Systems; AF2746; 1:100), or rabbit polyclonal antibodies against cleaved (activated) Caspase-3 (Cell Signaling Technology;

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NeuroD1 Antibody

NeuroD1 Antibody

NeuroD1 Antibody

NeuroD1 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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NeuroD1 Antibody from R&D Systems, a Bio-Techne Brand

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