PMP70 Antibody PA1-650 from Thermo Fisher Scientific

Product Specs
ItemPMP70 Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA1-650
NCBI Gene AliasesCBAS5, ABC43, PMP70, PMP68, Pxmp1, PXMP1, ZWS2
TargetPMP70
HostRabbit
FormatPBS with 1mg/mL BSA and 0.05% sodium azide
Conjugate/TagUnconjugated
Quantity100 µg
ApplicationsFlow Cytometry, Immunocytochemistry, Western Blot
ReactivityHuman, Mouse, Rat
ClonalityPolyclonal
NCBI Full Gene NameATP binding cassette subfamily D member 3, ATP-binding cassette, sub-family D (ALD), member 3
Concentration1 mg/mL
ImmunogenSynthetic Peptide: C N(644) Y E F K K I T E D T V E F G S(659)
Storage Temperature-20° C, Avoid Freeze/Thaw Cycles
PurityAntigen affinity chromatography
Antibody TypePrimary
Storage-20°C, Avoid Freeze/Thaw Cycles
IsotypeIgG

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(1) Reversibility and therapeutic feasibility of DNM1L-associated neurodevelopmental disordersExperimental & Molecular MedicineMarch 5, 2026Ki Hurn So, Se Hee Kim, Shinyoung Jang, Hyeun Deok Sang, Eun-Jin Yun, Hee-Jung Choi, Jong-Hee Chae, Seung Tae Baekmounted with 80% glycerol in PBS. The primary antibodies used were as follows: PMP70 (Invitrogen, #PA1-650, 1:500), Ctip2 (Abcam, #ab18465, 1:500), Satb2 (Abcam #ab51502, 1:400), Ki67 (Abcam, ab15580, 1:500),

(2) VPS13A Deficiency Leads to Impaired Lipid Distribution and Alteration of Mitochondrial Calcium Homeostasis in Fibroblasts of VPS13A Disease PatientsMovement DisordersJanuary 19, 2026Dajana Grossmann, Adrian Spranger, Emily Fischer, Johanna W. Schubarth, Jenny Leopold, Hannes Glaß, Sebastian Klicker, My Uyen Dang Thi, Anna Elisabeth Bartalis, Andreas Hermann, et al.incubated with primary antibodies against TOM20 (Santa Cruz: sc‐17764; 1:1000), PMP70 (Invitrogen: PA1‐650; 1:1000), Catalase (Cell Signaling Technology: 12980S; 1:1000), or KDEL (Invitrogen: MA5‐34715; 1:1000)

(3) Epigenetic Histone β-Hydroxybutyrylation Contributes to Renoprotection by β-Hydroxybutyrate in the Dahl RatHypertensionOctober 1, 2025Juthika Mandal, Sachin Aryal, Ishan Manandhar, Saroj Chakraborty, Xue Mei, Beng San Yeoh, Blair Mell, Andrew Kleinhenz, Ramakumar Tummala, Tao Yang, et al.paraffin and 5-µm-thick sections were prepared. Rabbit anti-PMP70 antibody (Thermo Fisher Scientific, Cat# PA1-650, 1:100 dilution) was used and detected using the Vectastain Elite ABC kit and SigmaFast 3,3-Diaminobenzidine

(4) The loss of OPA1 accelerates intervertebral disc degeneration and osteoarthritis in aged miceNat CommunJuly 1, 2025Vedavathi Madhu, Miriam Hernandaz-Meadows, Ashley Coleman, Kimheak Sao, Kameron Inguito, Owen Haslam, Paige K. Boneski, Hiromi Sesaki, Ruteja A. Barve, John A. Collins, et al.with 1% BSA for 1 h. Cells were incubated with anti-OPA1 (1:200, 612607) (BD Bioscience), anti-PMP70 (PA1-650), anti-GM130 (MA5-35107) (Fisher Scientific, Pittsburgh, PA, USA), anti-EEA1 (24115), anti-BNIP3 (3769S),

(5) Peroxisomal ether-glycerophospholipid synthesis is dysregulated after TBIJournal of Lipid ResearchJune 1, 2025Amir A. Mehrabani-Tabari, Nivedita Hegdekar, Sabrina Bustos, Yulemni Morel, Yuanyuan Ji, Sazia Arefin Kachi, Olivia Pettyjohn-Robin, Sagarina Thapa, Maya Bhattiprolu, Marta M. Lipinski, et al.Thermo Scientific, PA5-87935), GNPAT (1:1000; Thermo Scientific, PA5-36447), ABCD3/PMP70 (1:1000, Thermo Scientific, PA1-650), α-Tubulin (1:500; AA4.3-s, developed by Walsh, C. and obtained from Developmental Studies Hybridoma

(6) The ketone body β-Hydroxybutyrate mediated epigenetic chromatin β-hydroxybutyrylation protects kidneysbioRxivMay 8, 2025Juthika Mandal, Sachin Aryal, Ishan Manandhar, Saroj Chakraborty, Xue Mei, Beng San Yeoh, Blair Mell, Andrew Kleinhenz, Ramakumar Tummala, Tao Yang, et al.Sections were stained with Hematoxylin & eosin. Rabbit anti-PMP70 antibody (ThermoFisher Scientific, Cat# PA1–650, 1:100 dilution) was used and detected by using Vectastain Elite ABC kit and SigmaFast 3,3-Diamino-benzidine

(7) Engineering a membrane protein chaperone to ameliorate the proteotoxicity of mutant huntingtinNat CommunJanuary 17, 2025Jeonghyun Oh, Christy Catherine, Eun Seon Kim, Kwang Wook Min, Hae Chan Jeong, Hyojin Kim, Mijin Kim, Seung Hae Ahn, Nataliia Lukianenko, Min Gu Jo, et al.Invitrogen, #26183) for hsPEX19-WT and its variants proteins and PMP70 antibody (1:200 dilution, Invitrogen, #PA1-650) in 0.1% BSA solution at 4 °C for two overnights. After washing with PBS, the cells were incubated with

(8) Organelle landscape analysis using a multiparametric particle-based methodPLoS biologySeptember 1, 2024Kurikawa Y, Koyama-Honda I, Tamura N, Koike S, Mizushima N.and reagents Rabbit polyclonal anti-LAMP1 (Abcam, ab24170) and anti-PMP70 (Thermo Fisher Scientific, PA1-650) antibodies were labeled with Alexa Fluor 680 and 594 NHS ester (Thermo Fisher Scientific, A20008, A20004),

(9) A dual role of the conserved PEX19 helix in safeguarding peroxisomal membrane proteinsiScienceApril 19, 2024Oh J, Kim DK, Ahn SH, Kim HM, Cho H.antibody,Licor,Cat#926–32211; RRID: AB_621843 GFP antibody,Abcam,Cat#ab13970; RRID: AB_300798 PMP70 antibody,Invitrogen,Cat#PA1-650; RRID: AB_2219912 "Goat anti-Rabbit IgG (H + L) Cross-Adsorbed Secondary Antibody, Alexa Fluor™ 568",Invitrogen,Cat#A-11011;

(10) Modulation of peroxisomal import by the PEX13 SH3 domain and a proximal FxxxF binding motifNature communicationsApril 18, 2024Gaussmann S, Peschel R, Ott J, Zak KM, Sastre J, Delhommel F, Popowicz GM, Boekhoven J, Schliebs W, Erdmann R, et al.Cells were then incubated with the primary antibody targeting PMP70 (rabbit, 1:500 in D’PBS, Invitrogen PA1-650) for 30 min. Afterwards, the secondary antibody goat-α-rabbit IgG Alexa Fluor 594 (Invitrogen) was added

(11) Fatty acid-binding proteins 3, 7, and 8 bind cholesterol and facilitate its egress from lysosomesThe Journal of cell biologyApril 1, 2024Fang XX, Wei P, Zhao K, Sheng ZC, Song BL, Yin L, Luo J.BD Biosciences), mouse anti-LAMP1 (H4A3; Developmental Studies Hybridoma Bank), rabbit anti-PMP70 (PA1-650; Thermo Fisher Scientific), rabbit anti-FLAG tag (20543-1-AP; Proteintech), mouse anti-FLAG tag (F3165;

(12) ATM deficiency differentially affects expression of proteins related to fatty acid oxidation and oxidative stress in a sex-specific manner in response to Western-type diet prior to and following myocardial infarctionLife sciencesApril 1, 2024Wang-Heaton H, Wingard MC, Dalal S, Shook PL, Connelly BA, Johnson P, Nichols PL, Singh M, Singh K.Santa Cruz Biotechnology), Nox4 (1:1000; Cat# NB110–58849, Novus Biologicals), and PMP70 (1:1000; Cat# PA1–650, Invitrogen). The immune complexes were detected using corresponding secondary antibodies and chemiluminescent

(13) Cationic amphiphilic drugs induce accumulation of cytolytic lysoglycerophospholipids in the lysosomes of cancer cells and block their recycling into common membrane glycerophospholipidsMolecular biology of the cellMarch 1, 2024Nielsen IØ, Clemmensen KKB, Fogde DL, Dietrich TN, Giacobini JD, Bilgin M, Jäättelä M, Maeda K.sc-374599), anti-Golgin-97 (Thermo Fisher Scientific, A-21270), anti-PMP70 (Thermo Fisher Scientific, PA1-650), anti-β-actin (Sigma-Aldrich, A2228), anti-mouse IgG-HRP (Agilent DAKO, P0260), anti-Rabbit IgG-HRP

(14) The loss of OPA1 accelerates intervertebral disc degeneration and osteoarthritis in aged miceResearch SquareFebruary 21, 2024Makarand Risbud, Vedavathi Madhu, Miriam Hernandez-Meadows, Ashley Coleman, Kimheak Sao, Kameron Inguito, Owen Haslam, Paige Boneski, Hiromi Sesaki, John Collinsblocked with 1% BSA for 1 h. Cells were incubated with anti-OPA1 (612607) (BD Bioscience), anti-PMP70 (PA1–650), anti-GM130 (MA5–35107) (Fisher Scientific, Pittsburgh, PA, USA), anti-EEA1 (24115), anti-BNIP3 (3769S),

(15) Germ cell-specific deletion of Pex3 reveals essential roles of PEX3-dependent peroxisomes in spermiogenesisJournal of biomedical researchDecember 8, 2023Yao Y, Shi B, Zhang X, Wang X, Li S, Yao Y, Guo Y, Chen D, Wang B, Yuan Y, et al.PA5-60311, Invitrogen), anti-ABCD1 (1∶200; 11159-1-AP, Proteintech, Manchester, UK), anti-ABCD3 (1∶200; PA1-650, Invitrogen), anti-TEX14 (1∶500; ab41733, Abcam, Cambridge, UK), anti-DDX4 (1∶200; ab27591, Abcam),

(16) Autosomal dominant Zellweger spectrum disorder caused by de novo variants in PEX14 geneGenetics in medicine : official journal of the American College of Medical GeneticsNovember 1, 2023Waterham HR, Koster J, Ebberink MS, Ješina P, Zeman J, Nosková L, Kmoch S, Devic P, Cheillan D, Wanders RJA, et al.

(17) TTBK2 mutations associated with spinocerebellar ataxia type 11 disrupt peroxisome dynamics and ciliary localization of SHH signaling proteinsbioRxiv : the preprint server for biologyFebruary 1, 2023Muñoz-Estrada J, Nguyen AV, Goetz SC.from Dorus Gadella (Addgene, 85063). Antibodies. For immunostaining, rabbit anti-PMP70 (Invitrogen, PA1–650, 1:1,000), mouse anti-FLAG (Sigma-Aldrich, F1804, 1:2,000), anti-ACOX1 (ABclonal, A8091, 1:1,000), rabbit

(18) High expression of peroxisomal D-bifunctional protein in cytosol regulates apoptosis and energy metabolism of hepatocellular carcinoma cells via PI3K/AKT pathwayAmerican journal of cancer researchJanuary 1, 2023Zhang N, Wang YQ, Sun C, Shi Y, Hou LG, Yao M, Hu M, Wang XM, Ma PP, Li WJ, et al.

(19) Activation of autophagy triggers mitochondrial loss and changes acetylation profile relevant for mechanotransduction in bladder cancer cellsArchives of toxicologyJanuary 1, 2023Jobst M, Kiss E, Gerner C, Marko D, Del Favero G.anti-Caveolin-1 (ab192452, Abcam, dil 1:500), anti-Integrin beta 1 (ab30394, Abcam, dil 1:500), anti-PMP70 (PA1-650, Invitrogen dil 1:500), anti-CLUH (PA5-65,101, Invitrogen, dil 1:500), anti-KLF2 (ab203591, Abcam, dil

(20) Genotype-phenotype correlations and disease mechanisms in PEX13-related Zellweger spectrum disordersOrphanet journal of rare diseasesJuly 19, 2022Borgia P, Baldassari S, Pedemonte N, Alkhunaizi E, D'Onofrio G, Tortora D, Calì E, Scudieri P, Balagura G, Musante I, et al.sc-271477, 1:100), rabbit anti- peroxisomal integral membrane protein (PMP70) (Thermo Fisher Scientific, PA1650, 1:1000). Secondary antibodies were conjugated to AlexaFluor 488, AlexaFluor 555, or AlexaFluor 647

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PMP70 Antibody

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PMP70 Antibody from Thermo Fisher Scientific

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