WNK1 Antibody 4979S from Cell Signaling Technology

Product Specs
ItemWNK1 Antibody
CompanyCell Signaling Technology
Price $306.00 Inquire
Catalog Number4979S
Quantity100 µl
ApplicationsW
ReactivityH, Mk
TargetWNK1
HostRabbit
NCBI Gene AliasesHSAN2, HSN2, KDP, PPP1R167, PRKWNK1, PSK, p65
NCBI Full Gene NameWNK lysine deficient protein kinase 1
ClonalityPolyclonal
Research AreaPI3K / Akt Signaling
Molecular Weight230

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) LINC00632 combines with ERα to target VISTA expression, ameliorating endometriosis progressioniScienceMay 15, 2026Jue Zhu, Xinxin Xu, Tiantian Li, Ping Xu, Libo Zhu, Shaojie Ding, Jianzhang Wang, Jing Zhang, Yichen Chen, Xinmei ZhangAB32042 Anti-Caspase-3 antibody [E87],Abcam,Cat# AB32351 beta-Actin (13E5) Rabbit Monoclonal Antibody,CST,Cat# 4979 Anti-Phosphoserine Antibody,Sigma-Aldrich,Cat# AB1603 Anti-Phosphotyrosine Antibody,Sigma-Aldrich,Cat#

(2) Targeting WNK1 Releases Differentiation Block in Acute Myeloid LeukemiabioRxivApril 30, 2026Jordan D. Cress, Emily M. Katoni, Parameswaran Ramakrishnantransferred to a nitrocellulose membrane, and probed using the following antibodies: WNK1 (Cell Signaling, 4979S), SPAK (Santa Cruz, sc-517361), OSR1 (Santa Cruz, sc-271707), phospho SPAK/OSR1 (Sigma, 07–2273), C/EBPβ

(3) A Biphasic Effect of Alcohol on Endothelial Plasticity Through Regulation of Endothelial-to-Mesenchymal TransitionbioRxivApril 20, 2026Weimin Liu, Yusof Gusti, Fathima Athar, Naresh K Rajendran, Paul A. Cahill, Eileen M. Redmond# 36090, CST), SNAIL (Cat. # 3879, CST), GAPDH (Cat. # MA5-15738, Invitrogen), and β-Actin (Cat. # 4979, CST). Immunostaining Cells grown on fibronectin-coated coverslips were fixed in 10% formaldehyde

(4) Connexin 43 drives glioblastoma cancer stem cell phenotypes through a WNK lysine-deficient protein kinase 1-c-MYC signaling axisCell ReportsSeptember 23, 2025Erin E. Mulkearns-Hubert, Nicole Hajdari, Ellen S. Hong, Ashley P. Jacobs, Aymerick Gaboriau, Sophia Giltner, Gavin Tannish, Kristen E. Kay, Sabrina Z. Wang, Peter S. LaViolette, et al.anti-Cx43 at 1:1000 dilution (Cell Signaling, #3512S), anti-WNK1 at 1:1000 dilution (Cell Signaling, #4979S), and anti-c-MYC at 1:1000 dilution (Cell Signaling, #9402S). The membranes were developed using the

(5) WNKs regulate mouse behavior and alter central nervous system glucose uptake and insulin signalingbioRxivOctober 19, 2024Ankita B. Jaykumar, Derk Binns, Clinton A. Taylor, Anthony Anselmo, Shari G. Birnbaum, Kimberly M. Huber, Melanie H. Cobb(Cell Signaling, 3729S), anti-OSR1 monoclonal antibody (VWR, 10624–616), anti-WNK1 antibody (Cell Signaling, 4979S), anti-pAKT S473 antibody (Cell Signaling Technology, 4060S), anti-pAKT T308 antibody (Cell Signaling Technology

(6) SMURF1/2 are novel regulators of WNK1 stabilitybioRxivSeptember 21, 2024Ankita B. Jaykumar, Sakina Plumber, Derk Binns, Chonlarat Wichaidit, Katherine Luby-Phelps, Melanie H. Cobb(Cell Signaling, 3729S), anti-OSR1 monoclonal antibody (VWR, 10624–616), anti-WNK1 antibody (Cell Signaling, 4979S), anti- GAPDH antibody (Cell signaling Technology, 97166L), anti-SMURF1 antibody (Santa Cruz Biotechnology,

(7) SMURF1/2 Are Novel Regulators of WNK1 StabilityKinases and PhosphatasesSeptember 20, 2024Ankita B. Jaykumar, Sakina Plumber, Derk Binns, Chonlarat Wichaidit, Katherine Luby-Phelps, Melanie H. Cobbanti-OSR1 monoclonal antibody (VWR, Radnor, PA, USA; 10624-616), anti-WNK1 antibody (Cell Signaling, USA; 4979S), anti- GAPDH antibody (Cell Signaling Technology, USA; 97166L), anti-SMURF1 antibody (Santa Cruz Biotechnology,

(8) Focal adhesion kinase confers lenvatinib resistance in hepatocellular carcinoma via the regulation of lysine‐deficient kinase 1Molecular CarcinogenesisJanuary 1, 2024Wei Hou, Shaimaa A. Gad, Xianzhong Ding, Asha Dhanarajan, Wei Qiu"Anti-FAK Antibody, clone 4.47",05–537,MilliporeSigma,"WB, IF" Phospho-FAK (Tyr397) Antibody,3283S,Cell Signaling,"WB, IHC" WNK1 Antibody,4979S,Cell Signaling,WB WNK1 Polyclonal antibody,28357–1-AP,Proteintech,"WB, IHC" Anti-WNK1 antibody produced in rabbit

(9) Loss-of-function cancer-linked mutations in the EIF4G2 non-canonical translation initiation factorLife Sci AllianceDecember 21, 2023Sara Meril, Marcela Bahlsen, Miriam Eisenstein, Alon Savidor, Yishai Levin, Shani Bialik, Shmuel Pietrokovski, Adi Kimchirabbit anti-ROCK1 (cat# 4035, RRID:AB_2238679, 1:500; Cell Signaling Technology), rabbit anti-WNK1 (cat# 4979, RRID:AB_2216752, 1:500; Cell Signaling Technology) and mouse anti-tubulin (cat# T9026, RRID:AB_477593,

(10) Destabilized 3’UTR elements therapeutically degrade ERBB2 mRNA in drug-resistant ERBB2+ cancer modelsFrontiers in GeneticsJune 9, 2023Chidiebere U. Awah, Yana Glemaud, Fayola Levine, Kiseok Yang, Afrin Ansary, Fu Dong, Leonard Ash, Junfei Zhang, Olorunseun O. Ogunwobiwith anti-ERBB2(Human ErbB2/Her2 MAb Clone 191924) or anti-YES1 and WNK1 (Cell Signaling #65890 and #4979), CNOT1 (14276-1-AP) overnight in BSA. The primary antibody was removed, and secondary anti-mouse IR

(11) WNK1-OSR1 Signaling Regulates Angiogenesis-Mediated Metastasis towards Developing a Combinatorial Anti-Cancer StrategyInternational journal of molecular sciencesOctober 11, 2022Hou CY, Ma CY, Lin YJ, Huang CL, Wang HD, Yuh CH.(BIO-RAD, Hercules, CA, USA). All the data were analyzed by ImageJ. The primary antibodies were anti-WNK1 (#4979, Cell signaling, Danvers, MA, USA), anti-OSR1 (#3729, Cell signaling, MA, USA), anti-PPP2AA (#2039,

(12) WNK1 collaborates with TGF-β in endothelial cell junction turnover and angiogenesisProceedings of the National Academy of Sciences of the United States of AmericaJuly 26, 2022Jaykumar AB, Plumber S, Barry DM, Binns D, Wichaidit C, Grzemska M, Earnest S, Goldsmith EJ, Cleaver O, Cobb MH.(Cell Signaling, 3729S); anti–OSR1 monoclonal antibody (VWR, 10624–616); anti–WNK1 antibody (Cell Signaling, 4979S); anti–occludin monoclonal antibody (Fisher Scientific, 33–150-0); anti–occludin polyclonal antibody

(13) WNK1 Enhances Migration and Invasion in Breast Cancer ModelsMolecular Cancer TherapeuticsOctober 1, 2021Ankita B. Jaykumar et al.EMD Millipore, 07–2273), anti-OSR1 (Cell Signaling Technology, 3729S), anti-WNK1 (Cell Signaling Technology, 4979S), anti-p63 (Cell Signaling Technology, 4892), anti-pan-actin (Cell Signaling Technology, 4968S), anti-N-cadherin

(14) WNK1 Enhances Migration and Invasion in Breast Cancer ModelsMol Cancer TherJuly 12, 2021Ankita B. Jaykumar, Ji-Ung Jung, Pravat Kumar Parida, Tuyen T. Dang, Chonlarat Wichaidit, Ashari Rashmi Kannangara, Svetlana Earnest, Elizabeth J. Goldsmith, Gray W. Pearson, Srinivas Malladi, et al.EMD Millipore, 07–2273), anti-OSR1 (Cell Signaling Technology, 3729S), anti-WNK1 (Cell Signaling Technology, 4979S), anti-p63 (Cell Signaling Technology, 4892), anti-pan-actin (Cell Signaling Technology, 4968S), anti-N-cadherin

(15) Layer‐by‐layer nanoparticles for novel delivery of cisplatin and PARP inhibitors for platinum‐based drug resistance therapy in ovarian cancerBioengineering & Translational MedicineJune 14, 2019Lawrence B. Mensah et al.CD44 mouse (8E2, #5640), PTEN (D4.3, #9188), EGFR rabbit, ß‐actin mouse, and ß‐actin rabbit (13E5, #4979; all Cell Signaling Technology, Danvers, MA). Anti‐rabbit IgG horseradish peroxidase (HRP)‐conjugated

(16) Design and Synthesis of Antifungal Compounds from 1,2,3-Triazoles through the Click Chemistry ApproachOrganic & Medicinal Chemistry International JournalMarch 12, 2019Erick Cuevas YañezClick Chemistry for Drug Development and Diverse Chemical-Biology Applications. Chem Rev 113(7): 4905-4979. 12. Agalave SG, Maujan SR, Pore VS (2011) Click Chemistry: 1,2,3-Triazoles as Pharmacophores. Chem

(17) miR-199a-3p Modulates MTOR and PAK4 Pathways and Inhibits Tumor Growth in a Hepatocellular Carcinoma Transgenic Mouse ModelMolecular therapy. Nucleic acidsJune 1, 2018Callegari E, D'Abundo L, Guerriero P, Simioni C, Elamin BK, Russo M, Cani A, Bassi C, Zagatti B, Giacomelli L, et al.monoclonal antibody (Clone 2D9, TA802519; OriGene Technologies) or anti-β-actin monoclonal antibody (13E5, #4979; Cell Signaling) were used as housekeeping genes. A horseradish-peroxidase-conjugated secondary antibody

(18) PDK1‑WNK1 signaling is affected by HBx and involved in the viability and metastasis of hepatic cellsOncology LettersFebruary 8, 2018Chaoying Li, Cong Lin, Xianling Cong, Ying Jiangincubated overnight at 4˚C with the following primary antibodies: Rabbit anti‑WNK1 antibody (1:500; cat. no. 4979S; Cell Signaling Technology, Inc., Danvers, MA, USA), anti‑p‑PDK1 (Ser241) antibody (1:500; cat. no.

(19) Protein kinase A determines platelet life span and survival by regulating apoptosisThe Journal of clinical investigationDecember 1, 2017Zhao L, Liu J, He C, Yan R, Zhou K, Cui Q, Meng X, Li X, Zhang Y, Nie Y, et al.weeks of age unless otherwise specified. Antibodies and reagents. Antibodies against β-actin (catalog 4979), mouse PKA C-α (catalog 4782), p53 (catalog 2524), phospho-p53 (ser15) (catalog 9284), and human PKA

(20) Secreted protein acidic and rich in cysteine (SPARC) induces cell migration and epithelial mesenchymal transition through WNK1/snail in non-small cell lung cancerOncotargetSeptember 8, 2017Jen-Yu Hung, Meng-Chi Yen, Shu-Fang Jian, Cheng-Ying Wu, Wei-An Chang, Kuan-Ting Liu, Ya-Ling Hsu, Inn-Wen Chong, Po-Lin Kuop-Src (Y527) (1:1000, #2105). Src (1:1000, #2109), p-WNK1(T60) (1:1000, #4946), and WNK1 (1:1000, #4979) were obtained from Cell Signaling Technology; antibody of α-smooth muscle actin (1:1000, #A5228) was

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WNK1 Antibody

WNK1 Antibody from Cell Signaling Technology

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Cell Signaling Technology

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WNK1 Antibody from Cell Signaling Technology

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