p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb 4695S from Cell Signaling Technology

Product Specs
Itemp44/42 MAPK (Erk1/2) (137F5) Rabbit mAb
CompanyCell Signaling Technology
Price Pricing Info Supplier Page View Company Product Page
Catalog Number4695S
Quantity200 µl
ApplicationsW, IP, IHC-P, IF-IC, FC-FP
ReactivityH, M, R, Hm, Mk, Mi, Dm, Z, B, Dg, Pg, Ce
HostRabbit
ClonalityMonoclonal
TargetERK1;ERK2
NCBI Full Gene Namemitogen-activated protein kinase 3, mitogen-activated protein kinase 1
NCBI Gene AliasesP44MAPK, p44-ERK1, ERK-2, p41, ERK, HUMKER1A, PRKM3, PRKM2, P44ERK1, p44-MAPK, MAPK2, NS13, p40, ERK-1, p38, HS44KDAP, ERK1, ERK2, p42-MAPK, P42MAPK, p41mapk, ERT1, PRKM1, ERT2
Research AreaMAP Kinase Signaling
IsotypeIgG
Clone137F5
Molecular Weight42, 44

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Cell Signaling Technology

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Danvers, Massachusetts 01923

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Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Casein kinase-2 inhibition promotes retinal ganglion cell survival after acute intraocular pressure elevationNeural Regeneration ResearchMay 1, 2024Meng Wang, Shi-Qi Yao, Yao Huang, Jia-Jian Liang, Yanxuan Xu, Shaowan Chen, Yuhang Wang, Tsz Kin Ng, Wai Kit Chu, Qi Cui, et al.anti-extracellular-signal-regulated kinase (Erk) p44/p42 antibody (1:1000, Cell Signaling Technology, Beverly, MA, USA, Cat# 4695, RRID: AB_390779), rabbit anti-phospho-Erk p44/p42 antibody (1:1000, Cell Signaling Technology, Cat#

(2) DOCK1 insufficiency disrupts trophoblast function and pregnancy outcomes via DUSP4-ERK pathwayLife Science AllianceFebruary 1, 2024Yichi Xu, Xiaorui Liu, Weihong Zeng, Yueyue Zhu, Junpeng Dong, Fan Wu, Cailian Chen, Surendra Sharma, Yi LinB1,"WB(1:1,000)",Proteintech,#66095-1-lg β-Actin,"WB(1:2,000)",CST,#4970 Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204),"WB(1:1,000)",CST,#4370 p44/42 MAPK (Erk1/2),"WB(1:1,000)",CST,#4695 β-Catenin,"WB(1:1,000)",CST,#8480 Ubiqutin,"WB(1:1,000)",CST,#3936 Ki67,IHC(1:500),Abcam,#ab15580 CK7,IF(1:200),Abcam,#ab181598 HLA-G,IF(1:200),Proteintech,#66447-1-Ig Anti-rabbit

(3) Engineered a dual-targeting HA-TPP/A nanoparticle for combination therapy against KRAS-TP53 co-mutation in gastrointestinal cancersBioactive MaterialsFebruary 1, 2024Yong Mei, Xiaohua Qin, Zhenyu Yang, Shiyao Song, Xiaoting Liu, Chong Wu, Jieying Qian, Xiaowan Huang, Yunjiao Zhang, Weiling HeK48-linkage specific polyubiquitin antibody (Cell Signaling Technology, 1280S), anti-p44/42 MAPK (ERK1/2) (Cell Signaling Technology, 4695S), anti-phospho-p44/42 MAPK (p-ERK1/2) (Cell Signaling Technology, 4370S), anti-AKT (Cell Signaling Technology,

(4) The MORC2 p.S87L mutation reduces proliferation of pluripotent stem cells derived from a patient with the spinal muscular atrophy-like phenotype by inhibiting proliferation-related signaling pathwaysNeural Regeneration ResearchJanuary 1, 2024Sen Zeng, Honglan Yang, Binghao Wang, Yongzhi Xie, Ke Xu, Lei Liu, Wanqian Cao, Xionghao Liu, Beisha Tang, Mujun Liu, et al.Cell Signaling Technology, Cat# 4060, RRID: AB_2315049), ERK1/2 (human, 1:2000, Cell Signaling Technology, Cat# 4695, RRID:AB_390779), and phospho-ERK1/2 (human, 1:2000, Cell Signaling Technology, Cat# 4370, RRID: AB_2315112).

(5) ALYREF-mediated RNA 5-Methylcytosine modification Promotes Hepatocellular Carcinoma Progression Via Stabilizing EGFR mRNA and pSTAT3 activationInt J Biol SciJanuary 1, 2024Jiayida Nulali, Kaiwen Zhang, Manmei Long, Yueyue Wan, Yu Liu, Qianyue Zhang, Liu Yang, Jun Hao, Linhua Yang, Huaidong SongAly/Ref (ab202894) were from abcam, anti-EGFR (4267), anti-STAT3 (9139), anti-p-STAT3 (9145), anti-ERK (4695), anti-p-ERK (8544), anti-AKT (4691S), and anti-p-AKT (4060) were from Cell Signaling Technology (CST).

(6) Glucocorticoids modulate neural activity via a rapid non-genomic effect on Kv2.2 channels in the central nervous systemNeurobiology of StressJanuary 1, 2024Yuqi Wang, Yuchen Zhang, Jiawei Hu, Chengfang Pan, Yiming Gao, Qingzhuo Liu, Wendong Xu, Lei Xue, Changlong Huat room temperature and then incubated with primary antibodies overnight at 4 °C (anti-ERK, 1:1000, 4695S, Cell Signaling Technology, USA; anti-pERK, 1:1000, 4370S, Cell Signaling Technology, USA; anti-beta-tubulin,

(7) Enhanced Bone Regeneration through Regulation of Mechanoresponsive FAK-ERK1/2 Signaling by ZINC40099027 during Distraction OsteogenesisInternational Journal of Medical SciencesJanuary 1, 2024Shanyu Li, Hongxiao Wu, Feng Wang, Lingchi Kong, Yifan Yu, Rongtai Zuo, Haoyu Zhao, Jia Xu, Qinglin Kang#3285, Cell Signaling Technology, Danvers, MA, USA), p-FAK (1:1000, ab81298, Abcam), ERK1/2 (1:1000, #4695, Cell Signaling Technology), p-ERK1/2 (1:1000, #4370, Cell Signaling Technology), RUNX2 (1:1000, #12556,

(8) A novel FGFR1 inhibitor CYY292 suppresses tumor progression, invasion, and metastasis of glioblastoma by inhibiting the Akt/GSK3β/snail signaling axisGenes & DiseasesJanuary 1, 2024Yanran Bi, Ruiling Zheng, Jiahao Hu, Ruiqing Shi, Junfeng Shi, Yutao Wang, Peng Wang, Wenyi Jiang, Gyudong Kim, Zhiguo Liu, et al.1:2000), anti-phosphorylated AKT (Cell Signaling, #4060, 1:1000), anti-p44/42 MAPK (Cell Signaling, #4695, 1:3000), anti-phosphorylated p44/42 MAPK (Cell Signaling, #4370, 1:3000), anti-GAPDH (Cell Signaling,

(9) Lucialdehyde B suppresses proliferation and induces mitochondria-dependent apoptosis in nasopharyngeal carcinoma CNE2 cellsPharmaceutical BiologyDecember 31, 2023Lingxue Liu, Zhangning Yu, Jing Chen, Benchen Liu, Changhui Wu, Ye Li, Jianhua Xu, Peng LiRoche (Basel, Switzerland). Antibodies against Ras (14429S), c-Raf (53745S), p-c-Raf (9421S), Erk1/2 (4695S), p-Erk1/2 (4370S), GAPDH (5174S), caspase-9 (9508 T), caspase-3 (9665 T), Bcl-2 (15071 T), cleaved

(10) DNMT1 expression partially dictates 5-Azacytidine sensitivity and correlates with RAS/MEK/ERK activity in gastric cancer cellsEpigeneticsDecember 31, 2023Zhangqian Chen, Lin Zhang, Yang Yang, Haiming Liu, Xiaoyu Kang, Yongzhan Nie, Daiming Fanantibodies. DNMT1 (1:1000, CST, #28754), KRAS (1:1000, Abcam, ab275876), P44/42 MAPK (Erk1/2) (1:1000, CST, #4695), phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (1:1000, CST, #4370), MEK1/2 (1:1000, CST, #8727), phospho-MEK1/2

(11) Muscone inhibits angiotensin II–induced cardiac hypertrophy through the STAT3, MAPK and TGF-β/SMAD signaling pathwaysMol Biol RepDecember 29, 2023Yi-jiang Liu, Jia-jia Xu, Cui Yang, Yan-lin Li, Min-wei Chen, Shi-xiao Liu, Xiang-hui Zheng, Ping Luo, Rui Li, Di Xiao, et al.Cell Signaling Technology), p-STAT3 (1:1,000, Cat. No. 9145 S, Cell Signaling Technology), ERK (1:1,000, Cat. No. 4695 S, Cell Signaling Technology), p-ERK (1:1,000, Cat. No. 4370 S, Cell Signaling Technology), p-P38 (1:1,000,

(12) Discovery of KRB-456, a KRAS G12D Switch-I/II Allosteric Pocket Binder That Inhibits the Growth of Pancreatic Cancer Patient-derived TumorsCancer Res CommunDecember 28, 2023Aslamuzzaman Kazi, Alok Ranjan, Vasantha Kumar M.V., Bogos Agianian, Martin Garcia Chavez, Vignesh Vudatha, Rui Wang, Rajanikanth Vangipurapu, Liwei Chen, Perry Kennedy, et al.catalog no. 4056S), AKT (catalog no. 9272S), Phospho-Erk1/2 (catalog no. 4370S), Erk1/2 (catalog no. 4695S), Phospho-S6 Ribosomal Protein (Ser 235/236; catalog no. 4858S), S6 Ribosomal Protein (catalog no.2217S),

(13) Long-term administration of probiotics prevents gastrointestinal mucosal barrier dysfunction in septic mice partly by upregulating the 5-HT degradation pathwayOpen Med (Wars)December 26, 2023Xiaopeng Cao, Hui Zhao, Zhimin Liang, Yi Cao, Min MinCST), p38 (1:1,000, #8690; CST), phospho-p38 (1:1,000, #4511; CST), p44/42 MAPK (Erk1/2) (1:1,000, #4695; CST), and phospho-p44/42 MAPK (Erk1/2) (1:1,000, #4370; CST). After incubation with primary antibodies

(14) Butylphthalide improves brain damage induced by renal ischemia-reperfusion injury rats through Nrf2/HO-1 and NOD2/MAPK/NF-κB pathwaysRenal FailureDecember 22, 2023Jingjing Min, Qi Chen, Mengxiong Pan, Tan Liu, Qun Gu, Dongwei Zhang, Ru SunAntibody,Affinity,DF12125,1:1000 p-ERK1/2 Antibody,Cell Signaling Technology,4370T,1:1000 ERK1/2 Antibody,Cell Signaling Technology,4695T,1:1000 p-JNK Antibody,Affinity,AF3318,1:1000 JNK Antibody,Affinity,AF6318,1:1000 p-p38 Antibody,Affinity,AF4001,1:1000 p38

(15) Diabetic state of human coronary artery endothelial cells results in altered effects of bone mesenchymal stem cell-derived extracellular vesiclesPhysiol RepDecember 19, 2023Cynthia M. Xu, Catherine Karbasiafshar, Rayane Brinck-Teixeira, Mark Broadwin, Frank W. Sellke, M. Ruhul Abid(Cell Signaling, #4370, 1:2000), anti‐p44/42 mitogen‐activated protein kinase (ERK) (Cell Signaling, #4695, 1:1000), anti‐mammalian target of rapamycin (mTOR) (Cell Signaling, #2972, 1:1000), anti‐phospho‐endothelial

(16) Gut-microbiota prompt activation of natural killer cell on alcoholic liver diseaseGut MicrobesDecember 18, 2023Jung A Eom, Jin-Ju Jeong, Sang Hak Han, Goo Hyun Kwon, Kyeong Jin Lee, Haripriya Gupta, Satya Priya Sharma, Sung-Min Won, Ki-Kwang Oh, Sang Jun Yoon, et al.Phospho-p38 MAPK (Thr180/Tyr182) (D3F9) #4511;Cell signaling, 1:1000, p44/42 MAPK (Erk1/2) (137F5) #4695;Cell signaling, 1:2000, Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) #4370; Abcam, 1:500,

(17) Cosmosiin Induces Apoptosis in Colorectal Cancer by Inhibiting PD-L1 Expression and Inducing ROSAntioxidants (Basel)December 18, 2023Jung Ho Han, Eun-Ji Lee, Wonyoung Park, Jang-Gi Choi, Ki-Tae Ha, Hwan-Suck ChungPARP, and cleaved-PARP were purchased from Cell Signaling Technology (#13684S, #4060S, #4691S, #4370S, #4695S, #9542S, #9541S, Danvers, MA, USA). Antibodies targeting B-cell lymphoma-2 (Bcl-2) and Bcl-2-associated

(18) SHP2 inhibitors maintain TGFβ signalling through SMURF2 inhibitionNPJ Precis OncolDecember 15, 2023Xianning Lai, Sarah Kit Leng Lui, Hiu Yan Lam, Yuta Adachi, Wen Jing Sim, Natali Vasilevski, Nicola J. Armstrong, Stephanie Claire Bridgeman, Nathan Michael Main, Tuan Zea Tan, et al.Cell Signalling Technologies: anti-p-SMAD2 (#3101), anti-SMAD2 (#3103), anti-pERK (#4370), anti-ERK (#4695), anti-SMAD4 (#38454), anti-GST (#2622), and anti-SHP2 (#3397). The following antibodies were purchased

(19) Fructose-induced mTORC1 Activation Promotes Pancreatic Cancer Progression through Inhibition of AutophagyCancer ResearchDecember 15, 2023Yanfen Cui, Jianfei Tian, Zhaosong Wang, Hui Guo, He Zhang, Zhiyong Wang, Hui Liu, Weijie Song, Liming Liu, Ruinan Tian, et al.Cell Signaling Technology (CST)], pAMPK (2535, CST), p70S6K (34475, CST), p-p70S6K (92434S, CST), Erk (4695S, CST), pErk (4370S, CST), AKt (9272, CST), pAkt (2965S, CST), SQSTM1/p62 (5114S, CST), LC3 (4108, CST),

(20) Aberrant epithelial cell interaction promotes esophageal squamous-cell carcinoma development and progressionSignal Transduct Target TherDecember 15, 2023Liping Chen, Shihao Zhu, Tianyuan Liu, Xuan Zhao, Tao Xiang, Xiao Hu, Chen Wu, Dongxin LinTechnology) for 2 h at room temperature. Antibody against AKT (4691), Phospho-AKT (Ser473; 4060), ERK1/2 (4695), Phospho-ERK1/2 (T202/204; 4370), SRC (2109), Phospho-SRC (T416; 6943), CDK2 (2546), Cyclin D3 (2936),

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(1)

6/26/2023Total ERK1/2 Kangjin JeongMDA-MB-415 cells were treated with 0.3µM Neratinib and RSL3 for 3 days. The immunoblotting procedure is described below. Lyse cells by adding RIPA (with Proteinase and Phosphatase inhibitors) buffer... Read Review
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3/25/2022Great Antibody to Detect ERK through WBDr. Christian OstaleckiWe used this antibody to test for the expression of Erk in dendritic cells using western blot.
(1)

4/3/2020Expression of ERK1/2 in Microglia Cells Lisha JoshiA very good antibody.
(1)

1/27/2017p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb Anup KumarI am studying molecular anomalies in signaling pathways leading to cancers and development of anti cancer immune therapies.
(1)

12/30/2015Cell Signaling ERK Antibody Franz RicklefsI am investigating the role of the ERK-Pathway after extracellular vesicle treatment. I choose this product since i am also using the phosphor-Erk antibody from cell signaling and they are showing ... Read Review
(1)

9/8/2015p44/42 MAPK Antibody Used for Western Blot junyan taoI do cloning for animal experiments to use as liver cancer models and thus use a variety of molecular biology reagents including antibodies, plasmids, and RNA kits. This is a very good antibody used ... Read Review

Pharmaceuticals (Basel, Switzerland)

Experimental and Therapeutic Medicine

Antioxidants (Basel)

Current Biology

International Journal of Molecular Sciences

p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb from Cell Signaling Technology

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