Jak1 (6G4) Rabbit mAb 3344S from Cell Signaling Technology

Product Specs
ItemJak1 (6G4) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number3344S
Quantity100 µl
ApplicationsW, IHC-P
ReactivityH, M, R
TargetJAK1
HostRabbit
NCBI Gene AliasesAIIDE, JAK1A, JAK1B, JTK3
ClonalityMonoclonal
NCBI Full Gene NameJanus kinase 1
Research AreaImmunology and Inflammation
IsotypeIgG
Clone6G4
Molecular Weight130

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Alpha-Lipoic Acid Inhibits IFN-γ-Induced PD-L1 Expression in Prostate Cancer Cells and Enhances T-Cell-Mediated Anti-Tumor CytotoxicityAntioxidants (Basel)March 25, 2026Yi-Jan Hsia, Zhang-Min Lin, Tien-Sheng Tseng, Tz-Chong Choupurchased from Cell Signaling Technology (Danvers, MA, USA): p-JAK1 Tyr1034/1035 (74129, 1:1000), JAK1 (3344, 1:1000), STAT1 (14994, 1:1000), IRF-1 (8478, 1:1000), mTOR (2983, 1:1000), p-p70S6K Thr389 (9205, 1:1000),

(2) Enhancement of NK cell activity via DNA-sensing inhibition by Poxin transgeneJournal of Advanced ResearchMarch 1, 2026Ling-Zu Kong, Seok-Min Kim, Soo Yun Lee, In-Hwan Jang, Chunli Wang, Seona Jo, Se-Chan Oh, Sunyoung Lee, Ji Hyun Kim, Kee K. Kim, et al.NF-κB-P65 (#8242, CST), Histone H2A.X (#7631, CST), phospho-JAK1 (Tyr1034/1035) (#3331, CST), JAK1 (#3344, CST), phospho-STAT5 (Tyr694) (#9359, CST), and STAT5 (#9363, CST). After washing to remove excess primary

(3) A bacterial YopJ-family acetyltransferase suppresses host immune response by Nε-acetylation of JAK1Nature CommunicationsFebruary 18, 2026Tao-Tao Chen, Si-Ru Zheng, Binbin Yang, Qiuhua Lu, Xueyan Liu, Wenhong Zhong, Zhengfeng Jiang, Fan Li, Guosheng Hu, Yue Feng, et al.anti-DYKDDDDK tag (Proteintech, 66008-4-Ig), 1:5000; anti-HA (Proteintech, 51064-2-AP), 1:5000; anti-JAK1 (CST, 3344 T), 1:1000; anti-STAT1 (Abcam, ab109320), 1:2000; anti-STAT1 (phospho Y701) (Abcam, ab109457), 1:1000;

(4) The JAK1-STAT1 signaling pathway triggers inflammation responses in chronic obstructive sleep apnea rat modelPLOS OneFebruary 17, 2026Lin Yang, Jie Heincubated overnight at 4°C with primary antibodies: anti-JAK1 (1:1,000, Cell Signaling Technology, CST#3344), anti-p-JAK1 (Tyr1034/1035; 1:1,000, CST#74129), anti-STAT1 (1:1,000, CST#14994), anti-p-STAT1 (Tyr701;

(5) Dual TYK2/JAK1 Inhibition by Brepocitinib Reprograms Synoviocyte Pathobiology: Mechanistic Insights Into Targeted Therapy for Rheumatoid ArthritisIranian Journal of Pharmaceutical ResearchFebruary 1, 2026Umar Saeed, Zahra Zahid Piracha, Andromeda M. Nauli, Surya M. Naulifrom cell signaling technology (CST; catalog numbers: p-TYK2 #9321, TYK2 #14193, p-JAK1 #3331, JAK1 #3344, p-STAT1 #7649, STAT1 #14994, p-STAT3 #9145, STAT3 #12640, BAX #2772, BCL-2 #4223, cleaved caspase-3

(6) Dose-dependent activation of the Hippo pathway by Type I and Type III interferons suppresses tissue repair by human bronchial epithelial cellsPLOS BiologyJanuary 26, 2026Krupakar V. Subramaniam, Hui Jing Lim, Bao Wang, Valia T. Mihaylova, Evrett N. Thompson, Diane S. Krause, Ellen F. FoxmanThr180 (Cell Signaling, #49332, 1:1,000), MST1 (Cell Signaling, #14946, 1:1,000), JAK1 (Cell Signaling, #3344, 1:1,000), phospho-STAT1 Tyr701 (Cell Signaling, #9167, 1:1,000), STAT1 (Cell Signaling, #9172, 1:1,000),

(7) CRISPR screens in the context of immune selection identify CHD1 and MAP3K7 as mediators of cancer immunotherapy resistanceCell Reports MedicineJanuary 20, 2026Alex Watterson, Gabriele Picco, Vivien Veninga, Youhani Samarakoon, Chiara M. Cattaneo, Sara F. Vieira, Emre Karakoc, Shriram Bhosle, Thomas W. Battaglia, Sarah Consonni, et al.(#4351, 1:1,000), MAP3K7 (#45206, 1:500), STAT1 (#9172, 1:1,000), pSTAT1-Y710 (#7649, 1:1,000), JAK1 (#3344, 1:1,000), JAK2 (#3230, 1:1,000), Cas9 (#14697, 1:1,000), CDX2 (#3977, 1:1,000), vinculin (#13901, 1:1,000),

(8) Thimerosal Inhibits Tumor Malignant Progression through Direct Action and Enhancing the Efficacy of PD-1-Based ImmunotherapyOncology ResearchJanuary 19, 2026Ping Wang, Yan-Han Chen, Ze-Tao Zhan, Jun-Xiang Zeng, Yu Chen, Yuan Lin, Tao Chen, Wei-Jie Zhouanti-α-tubulin (1:10,000, HRP-66031, RRID: AB_2687491, Proteintech, Chicago, IL, USA); anti-JAK1 (1:1000, 3344T, RRID: AB_2265054, Cell Signaling Technology, Danvers, MA, USA); anti-p-JAK1 (1:200, 3331S, RRID: AB_2265057,

(9) ANGPTL8 links refeeding to monocyte dynamics and metabolic inflammation via the CCL5-CCR5 axisJCI InsightJanuary 9, 2026Ran-Ran Kan, Si-Yi Wang, Xiao-Yu Meng, Li Huang, Yu-Xi Xiang, Bei-Bei Mao, Hua-Jie Zou, Ya-Ming Guo, Li-Meng Pan, Pei-Qiong Luo, et al.anti-phospho-P38-MAPK (Thr180/Tyr182; Cell Signaling Technology, catalog 4511T), anti-JAK1 (Cell Signaling Technology, catalog 3344T), anti-phospho-JAK1 (Cell Signaling Technology, catalog 3331S), anti-STAT1 (Cell Signaling Technology,

(10) Berberine suppresses hepatocellular carcinoma progression by blocking IL-4-JAK1-STAT6-mediated M2 polarization of macrophageFrontiers in PharmacologyJanuary 8, 2026Peng Wang, Yuwen Zhong, Mengkai Li, Qing Liang, Weiyi Jiang, Mengqi Zhuang, Xuecheng Ge, Huixing Li, Yaoshuai Zhang, Yu Qiao, et al.overnight at 4 °C, including: p-STAT6 (56554S, CST), t-STAT6 (9362S, CST), p-JAK1 (3331S, CST), t-JAK1 (3344S, CST), β-actin (8457S, CST), Arg-1 (89872SF, CST), Retnla (Abcam, AB39626). Secondary antibodies were

(11) Structural variation drives enhancer hijacking via 3D genome disruption in ccRCCnpj Digital MedicineJanuary 6, 2026Yu Dong, Wenjiao Xia, Zitong Yang, Liangliang Ren, Hongru Wang, Yiyang Zhou, Qinchen Li, Zhi Chen, Zhinan Xia, Yichun Zheng, et al.and the following antibodies from Cell Signaling Technology (CST, Danvers, USA): anti-Jak1 (6G4) (#3344S), anti-phospho-Jak1 (Tyr1034/1035) (#3331S), anti-Stat3 (D3Z2G) (#12640S), anti-phospho-Stat3 (Tyr705)

(12) Photobiomodulation mitigates chondrocyte catabolism in osteoarthritis by modulating macrophage M1 polarization through the IL-6/JAK/STAT pathwayJ Orthop Surg ResDecember 24, 2025Haiming Wang, Wenhua Ning, Yiying Liu, Jing Nie, Shenao Du, Haowei Zhangdiluted at 1:1000: anti-IL-6 (Cat. No. 12153, Cell Signaling Technology, USA), anti-JAK1 (Cat. No. 3344, Cell Signaling Technology, USA), anti-JAK2 (Cat. No. 3230, Cell Signaling Technology, USA), anti-STAT3

(13) Baricitinib ameliorates skin fibrosis via direct fibroblast suppression and endothelial exosome-mediated paracrine signalingArthritis Research & TherapyDecember 20, 2025Zhanying Hou, Xiufeng Zhao, Fang Liu, Shi Xu1:1000, abcam, USA), Collagen III (ab184993, 1:1000, abcam), α-SMA (ab7817, 1 µg/mL, abcam), JAK1 (#3344, 1:1000, Cell Signaling Technology, USA), phosphorylated form of JAK1 (ab138005, 1:1000, abcam), JAK2

(14) Therapeutic stress triggers tumor STAT1 acetylation to disarm immunotherapyCell Reports MedicineNovember 18, 2025Po-Hsien Chiu, Kuan-Chen Lai, Hung-Ling Wang, Yao-Wen Chang, Wen-Chi Wu, Tien-Hua Chen, Yu-Shuen Tsai, Jie-Hong Song, Nai-Yun Sun, Gar-Yang Chau, et al.4370S, 4370P, 4370T); RRID:AB_2315112" Rabbit monoclonal Jak1 (6G4),Cell Signaling Technology,Cat# 3344; RRID:AB_2265054 Rabbit polyclonal Phospho-Jak1 (Tyr1022/1023),Cell Signaling Technology,Cat# 3331;

(15) Single-cell RNA sequencing reveals that kimchi dietary intervention modulates human antigen-presenting and CD4⁺ T cellsnpj Science of FoodNovember 17, 2025Wooje Lee, Ha-Rin Moon, Hasun Choi, Ho Jae Lee, Yebin Kim, Hyun Ju Kim, Ye-Rang Yun, Min-Sung Kwon, Sung Wook Hong7.6) for 1 h at room temperature and incubated overnight at 4°C with primary antibodies against JAK1 (#3344), phospho-JAK1 (Tyr1034/1035, #74129), JAK2 (#3230), phospho-JAK2 (Tyr1007/1008, #3776), STAT1 (#14994),

(16) Gingival mesenchymal stem cell-derived exosomal miR-23a-3p targets IL-6R to attenuate autoimmune insulitis: a cell-free therapeutic strategy for type 1 diabetesStem Cell Research & TherapyNovember 12, 2025Qing Qu, Si-Yu Liu, Bin Fu, Qiang Ao, Yong Long, Zi-Yu Liu, Wu-Mei Wei, Wei-Jian Hou, Xiao-Li Liu, Xiao-Hong Tianantibodies were utilized: JAK1 Rabbit mAb at a concentration of 1:1000 (Cell Signaling Technology; 3344 S), STAT3 Rabbit mAb at a concentration of 1:2000 (Cell Signaling Technology; 12640 S), IL-6R Rabbit

(17) IRF7 drives macrophages to kill bacteria and improves septic outcomes via autophagyJCI InsightNovember 10, 2025Guiming Chen, Kangxin Li, Haihua Luo, Lianxu Zhao, Yong JiangNB100-2220, 1:1,000), p62 (Cell Signaling Technology, 5114, 1:1,000), JAK1 (Cell Signaling Technology, 3344, 1:1,000), p-JAK1 (Cell Signaling Technology, 3331, 1:1,000), STAT3 (Cell Signaling Technology, 4904,

(18) Baitong Decoction Ameliorates DSS-Induced Colitis via Modulation of STING and JAK/STAT PathwaysACS OmegaNovember 4, 2025Yuhang Zhou, XiaoXian Wang, Jingxing Lyu, Qingfeng Ruan, Xiaoxuan Zeng, Yuqi Li, Chuanqi Huang, Hongfeng Xu2859S), anti-STAT3 (CST, 12640S), anti-STAT6 (CST, 5397S), anti-NF-κB (CST, 6956S), anti-JAK1 (CST, 3344S), antiphospho-JAK1 (CST, 3331S), anti-JAK2 (CST, 3230S), antiphospho-JAK2 (CST, 3771S), anti-Histone

(19) Effects of miR-210-3p/SDF2 and miR-31-5p/FGF7 from hypoxic endometrial exosomes on UCB-MSC proliferation, migration, and differentiationStem Cell Research & TherapyNovember 3, 2025Simiao Liu, Wanyu Zhang, Chengyan Deng, Hanbi Wangfor 1 h and incubated overnight at 4 °C with primary antibodies against p-JAK1/2 (3771, CST), JAK (3344, CST), STAT3 (4904, CST), p-STAT3 (9138, CST), CK19 (ab76539, Abcam), CD9 (ab236630, Abcam), Vimentin

(20) Endoplasmic Reticulum Stress Amplifies Cytokine Responses in Astrocytes via a PERK/eIF2α/JAK1 Signaling AxisGliaNovember 1, 2025Anirudhya Lahiri, Savannah G. Sims, Jessica A. Herstine, Alicia Meyer, Micah J. Marshall, Ishrat Jahan, Subhodip Adhicary, Allison M. Bradbury, Gordon P. Mearesbefore experimental treatments. 2.3 Antibodies and Reagents Primary antibodies used were: Anti JAK1 (3344), P‐eIF2α (3398), eIF2α (5324), P‐STAT1 (9167), STAT1 (14994), P‐STAT3 (9145), STAT3 (12640), PERK (3192),

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4/29/2022Good JAK1 Antibody for Total Protein Quantification Vanessa KelleyI generated a JAK1 knockout cell line and wanted to confirm that the JAK1 protein was completely depleted from these cells using a Western Blot. The antibody worked well and gave me a robust band in ... Read Review

Jak1 (6G4) Rabbit mAb

Jak1 (6G4) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Jak1 (6G4) Rabbit mAb from Cell Signaling Technology

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