cdc25C (5H9) Rabbit mAb 4688S from Cell Signaling Technology

Product Specs
Itemcdc25C (5H9) Rabbit mAb
CompanyCell Signaling Technology
Price $336.00 Inquire
Catalog Number4688S
Quantity100 µl
ApplicationsW
ReactivityH
TargetCdc25c
HostRabbit
NCBI Gene AliasesCDC25, PPP1R60
ClonalityMonoclonal
NCBI Full Gene Namecell division cycle 25C
Research AreaCell Cycle / Checkpoint Control
IsotypeIgG
Clone5H9
Molecular Weight60, 75

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Protein Kinase D2 Regulates GRASP65 Phosphorylation and Golgi Ribbon Unlinking During G2/M TransitionCellsMarch 21, 2026Inmaculada Ayala, Daniela Spano, Antonino ColanziCA, USA, #610823, 1:1000). Mouse anti-GAPDH (#97166S, 1:2000), rabbit anti-phospho-SAP/JNK (81E11) (#4688 1:1000), JNK2 (#4672S, 1:1000), and PKD2 (D1A7) (#8188S, 1:1000) were from Cell Signalling Technology

(2) The Effect of AZD5153 on Radiosensitivity in Pancreatic Cancer Cells Through ATM-chk1 PathwayDrug Des Devel TherMarch 16, 2026Lulin Zhu, Rong Dong, Gezi Yan, Haixin Zhu, Youyou Yan, Bo Zhang, Gang Wang, Nengming Lin, Biqin TanCat# 2873s), p-cdc25C (Cell Signaling Technology, Cat# 4901s), cdc25C (Cell Signaling Technology, Cat# 4688s), p-chk1 (Cell Signaling Technology, Cat# 2348s), chk1 (Abcam, Cat# ab40866), p-cdc2 (Cell Signaling Technology

(3) Methyl-cantharidimide suppresses cyclin-dependent kinase 1 (CDK1) and induces oxeiptosis in liver cancerJournal of Experimental & Clinical Cancer ResearchMarch 2, 2026Yi-Dong Li, Xiang Chen, Xing-Duo Dong, Zhiyong Ding, Zhe-Sheng Chen, Shuo Fangobtained from MedChemExpress LLC (Monmouth Junction, NJ, USA). Primary antibodies targeting CDK1/Cdc25C (#4688), AIF (#5318), KEAP1 (#8047), PGAM5 (#24584), β-Actin (#4970), Bax (#2772), Bcl-2 (#4223), and HRP-linked

(4) Novel Glycyrrhizinic Acid Derivative YCY ‐20 Inhibits Cerebral Ischemia/Reperfusion Induced Apoptosis via the AGE ‐ RAGE / MAPK PathwayCNS Neuroscience & TherapeuticsFebruary 17, 2026Jia Luo, Xue Qin, Jiaxin Chen, Xiushi Yu, Ziyun Liu, Jiyi Lv, Xinhui Pan, Yong Chen, Lili Wei1:2000, Cell Signaling Technology, no: 9252), (p‐JNK antibody 1:2000, Cell Signaling Technology, no:4688), (p‐P38 antibody 1:2000, Cell Signaling Technology, no: 4511), (P38 antibody 1:2000, Cell Signaling Technology

(5) Neutrophils Extracellular Traps Impair Lung Endothelial Proliferation in Sepsis via PLK1 Inhibition and Cell Cycle ArrestJ Inflamm ResDecember 27, 2025Chenyu Zhu, Mengdi Qu, Dan Wu, Yuxin Shi, Fu Zeng, Changhong Miao, Di ZhouCell Signaling Technology), anti-p-CDC25C (1:250, 9529, Cell Signaling Technology), anti-CDC25C (1:1000, 4688, Cell Signaling Technology), anti-CDK1 (1:1000, A0220, Abcolonol), and anti-β-actin (1:1000, 4970, Cell Signaling Technology

(6) Productive mRNA chromatin escape is promoted by PRMT5 activityMolecular CellNovember 6, 2025Joseph D. DeAngelo, Maxim I. Maron, Jacob S. Roth, Subray Hegde, Aliza M. Silverstein, Varun Gupta, Stephanie Stransky, Joel Basken, Joey Azofeifa, Charles C. Query, et al.AB_2302166 SNRPG,Proteintech,Cat#: 15084-1-AP; RRID: AB_2191789 Rme2s (SDMA),"Mark Bedford, PhD",#4688 Rme2a (ADMA),CST,Cat#: 13522S; RRID: AB_2665370 Rme1 (MMA),CST,Cat#: 8015S; RRID: AB_10891776 H3K27me3,CST,Cat#:

(7) The impact of evodiamine on human anaplastic thyroid cancer therapy—an in vitro and in vivo studyInternational Journal of Medical SciencesOctober 27, 2025Yin-Che Lu, Tsung-Hsing Lin, Kai-Liang Tang, Chin-Ho Kuo, Yi-Sheng Zhang, Yi-Ping Chang, Shu-Hsin Chen, Yi-Zhen Li, Pei-Wen Zhao, Jen-Hsien Lin, et al.previous studies 30-33. The primary antibodies used in this study included: cdc2 (#9116), cdc25C (#4688), p21 (#2947), caspase-3 (#9662), caspase-9 (#9502), and PARP (#9542) (from Cell Signaling Technology,

(8) Unveiling an Arpp-19 phosphorylation switch that grants chromosome stabilityCommun BiolMay 30, 2025Angela Flavia Serpico, Caterina Pisauro, Asia Trano, Domenico Grieco1:500), mouse anti-γ-tubulin (Cat# T5326, Clone GTU-88, Sigma-Aldrich; 1:1000), rabbit anti-Cdc25C (Cat# 4688S, Cell Signaling Technology; 1:1000), anti-Flag FITC (Cat# F4049, Sigma-Aldrich; 1:200). Rabbit polyclonal

(9) Transcriptomic Analyses of Ovarian Clear Cell Carcinoma Spheroids Reveal Distinct Proliferative Phenotypes and Therapeutic VulnerabilitiesCellsMay 27, 2025Bart Kolendowski, Sylvia Cheng, Yudith Ramos Valdes, Trevor G. Shepherd, Gabriel E. DiMattia(cleaved),Cell Signaling Technology,9661 CDK1,Cell Signaling Technology,9116 CDC25C,Cell Signaling Technology,4688 γH2AX,Cell Signaling Technology,9718 p-CDK1 (Tyr15),Cell Signaling Technology,4539 p-Histone H3 (Ser10),Cell Signaling Technology

(10) CBD promotes antitumor activity by modulating tumor immune microenvironment in HPV associated head and neck squamous cell carcinomaFront ImmunolMay 22, 2025Prakriti Sen, Sayed Sadat, Koji Ebisumoto, Riyam Al-Msari, Sayuri Miyauchi, Souvick Roy, Pardis Mohammadzadeh, Kristin Lips, Takuya Nakagawa, Robert Saddawi-Konefka, et al.signal-regulated kinase (pERK1/2), (#4695), SAPK/JNK (#9252), phospho-c-Jun N-terminal kinase (pJNK) (#4688), MAPKAPK-2 (#3042) and phospho-mitogen-activated-protein-kinase-activated-protein-kinase-2 (pMK-2)

(11) PLK1 inhibition delays mitotic entry revealing changes to the phosphoproteome of mammalian cells early in divisionThe EMBO JournalMarch 3, 2025Monica Gobran, Antonio Z Politi, Luisa Welp, Jasmin Jakobi, Henning Urlaub, Peter LenartAnti-Mouse IgG (IF),Jackson ImmunoResearch,615-545-214 Rabbit anti-Cdc25C (WB),Cell Signaling Technology,4688 Rabbit anti-Phospho-Cdc25C (Thr48) (WB),Cell Signaling Technology,9527 Rabbit anti-Phospho-cdc2/cdk1

(12) Nuclear PD-L1 triggers tumour-associated inflammation upon DNA damageEMBO reportsFebruary 1, 2025Nihira NT, Wu W, Hosoi M, Togashi Y, Sunada S, Miyoshi Y, Miki Y, Ohta T.anti-phospho Cdc25C (Ser216),Cell Signaling Technology,#9528 Rabbit anti- Cdc25C,Cell Signaling Technology,#4688 Rabbit anti-cGAS,Cell Signaling Technology,#15102 Rabbit anti-TBK1/NAK,Cell Signaling Technology,#38066 Rabbit

(13) A novel application perspective of the clinical-used drug verapamil on osteoporosis via targeting TxnipJournal of orthopaedic translationJanuary 1, 2025Cao X, Rong K, Li Y, Zhang P, Liu K, Cui L, Fu S, Hua Q, Yang X, Zhang H, et al.CST, 8943, 1:1000; phospho-I κ B α, CST, 2859, 1:500; I κ B α, CST, 4814, 1:1000; phospho-JNK, CST, 4688, 1:1000; JNK, CST, 9252, 1:1000; phospho-ERK, CST, 4370, 1:1000; ERK, CST, 4695, 1:1000; phospho-P38,

(14) O-GlcNAcylation of Focal Adhesion Kinase Regulates Cell Adhesion, Migration, and Proliferation via the FAK/AKT PathwayBiomoleculesDecember 10, 2024Zhiwei Zhang, Tomoya Isaji, Yoshiyuki Oyama, Jianwei Liu, Zhiwei Xu, Yuhan Sun, Tomohiko Fukuda, Haojie Lu, Jianguo Gu(611807) and Paxillin (610052) from BD Transduction Laboratories; O-GlcNAc (9875S), Phospho-SAPK/JNK (4688), SAPK/JNK (9252), Phospho-p44/42 MAPK (Erk1/2) (4370), p44/42 MAPK (Erk1/2) (4695), Phospho-AKT (4060),

(15) Imbalance of redox homeostasis and altered cellular signaling induced by the metal complexes of terpyridineScientific ReportsNovember 6, 2024Katarzyna Malarz, Patryk Ziola, Dawid Zych, Patryk Rurka, Anna Mrozek-WilczkiewiczTechnology - CST); IDH1 (#8137, CST); Nrf2 (#12721, CST); BID (#2002, CST); cdc2 (#9116, CST); cdc25c (#4688, CST); cyclin A2 (#4656, CST); cyclin B1 (#4138, CST); p21Waf1/Cip1 (#2947, CST); p27Kip1 (#3688, CST);

(16) Plant essential oils combined with organic acids restored lipopolysaccharide-induced leaky intestine via gut microbial modulation in weaned pigletsAnimal NutritionSeptember 1, 2024Xiaoyu Zheng, Yibo Wang, Xuemei Zhou, Tanyi Deng, Yueqi Zhao, Zhichao Fu, Yulong Wei, Wen Ma, Shihai Zhang, Wutai Guan, et al.Cambridge, UK), occludin (27260–1-AP, Proteintech, China), phosphorylated c-Jun N-terminal kinase (P-JNK) (4688S, Cell Signaling Technology, Boston, MA, USA), JNK (9252S, Cell Signaling Technology, Boston, MA, USA),

(17) Dietary Protease Supplementation Improved Growth Performance and Nutrients Digestion via Modulating Intestine Barrier, Immunological Response, and Microbiota Composition in Weaned PigletsAntioxidants (Basel)July 8, 2024Tao Liu, Wen Ma, Jun Wang, Yulong Wei, Yibo Wang, Zheng Luo, Ying Zhang, Xiangfang Zeng, Wutai Guan, Dan Shao, et al.USA)" P-JNK,Phospho-SAPK/JNK (Thr183/Tyr185) (81E11) Rabbit mAb #4668,4668S,"Cellsignaling(1:1000, 4688S, Cell Signaling Technology, Boston, MA, USA)" ERK,p44/42 MAPK (Erk1/2) Antibody #9102,9102S,"Cellsignaling(1:3000,

(18) Design, Synthesis, and Anti-Leukemic Evaluation of a Series of Dianilinopyrimidines by Regulating the Ras/Raf/MEK/ERK and STAT3/c-Myc PathwaysMoleculesApril 3, 2024Chaoyan Wang, Bo Wang, Yu Mou, Xiang Liu, Qiqing Chen, Weidong Pu, Qing Rao, Chunlin Wang, Jingrui Song, Yubing Huang, et al.Beyotime Biotechnology (Shanghai, China). PARP (9542S), caspase-3 (9662S), caspase-9 (9502S), CDC25C (4688S), p-CDC25C (4901T), MEK1/2 (87276T), p-MEK1/2 (9154T), p53 (#2527), and Anti-rabbit IgG (#7074) were

(19) Synthetic lethal combination of CHK1 and WEE1 inhibition for treatment of castration-resistant prostate cancerOncogeneMarch 7, 2024Yapeng Chao, Yuzhou Chen, Wenxiao Zheng, Kathryn Demanelis, Yu Liu, Jaclyn A. Connelly, Hong Wang, Song Li, Qiming Jane Wangp-S345-CHK1 (#2348), CHK1 (#6334), p-Y15-CDC2 (#9111), p-S428-ATR (#2853), p-S216-CDC25C (#9528), CDC25C (#4688), p-S139-His H2A.X (#9718), and p-S10-HistoneH3 (#53348) were purchased from Cell Signaling Technology.

(20) Transcriptomic, Proteomic, and Genomic Mutational Fraction Differences Based on HPV Status Observed in Patient-Derived Xenograft Models of Penile Squamous Cell CarcinomaCancersMarch 6, 2024Zacharias NM, Segarra L, Akagi K, Fowlkes NW, Chen H, Alaniz A, de la Cerda C, Pesquera P, Xi Y, Wang J, et al.(1:1000, 65939S, Cell Signaling, Danvers, MA, USA); p16 (1:1000, 80772S, Cell Signaling); CDC25C (1:1000, 4688S, Cell Signaling); and HPV16-E7 (1:1000, GTX133411, GeneTex, Irvine, CA, USA) and a corresponding secondary

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cdc25C (5H9) Rabbit mAb

cdc25C (5H9) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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cdc25C (5H9) Rabbit mAb from Cell Signaling Technology

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