Cyclin D1 (92G2) Rabbit mAb 2978S from Cell Signaling Technology

Product Specs
ItemCyclin D1 (92G2) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number2978S
Quantity100 µl
ApplicationsW, IHC-P
ReactivityH, M, R
TargetCyclin D1
HostRabbit
NCBI Gene AliasesBCL1, D11S287E, PRAD1, U21B31
ClonalityMonoclonal
NCBI Full Gene Namecyclin D1
Research AreaCell Cycle / Checkpoint Control
IsotypeIgG
Clone92G2
Molecular Weight36

Questions and Answers

Can this antibody be used for Western blotting in cancer research?

Yes, the Cyclin D1 (92G2) Rabbit mAb has been utilized in Western blotting applications, as evidenced by its use in studies investigating various cancer types, including nasopharyngeal carcinoma and glioblastoma, where it was employed to assess cyclin D1 protein levels in cell lines and tissue samples (, ).

What species does this antibody react with, and is it suitable for human studies?

The Cyclin D1 (92G2) Rabbit mAb is reactive with mouse, rat, and human species, making it suitable for studies involving human samples as well as animal models ().

Has this antibody been cited in studies related to cell cycle regulation?

Yes, this antibody has been cited in numerous studies focusing on cell cycle regulation, particularly in the context of cyclin D1's role in promoting the G1 to S phase transition, which is critical in cancer cell proliferation (, ).

Is this antibody effective for immunohistochemistry applications?

The Cyclin D1 (92G2) Rabbit mAb has been shown to work in immunohistochemistry applications, as indicated by its use in various studies to visualize cyclin D1 expression in tissue sections, contributing to the understanding of its role in tumor biology ().

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) COPB2 drives gastric cancer progression via PI3K/AKT/NF-κB signaling: a multi-omics and functional studyCell Adhesion & MigrationDecember 31, 2026Hailong Li, Dong Wei, Xiaqing Gao, Rong Su, Chunting Yang, Ping Tang, Xiqiu Yu, Yuhong WuABCAM), F2RL1 (1:1000, #6976, CST), CDK6 (1:1000, #3136, CST), MMP9 (1:1000, #13667, CST), CCND1 (1:500, #2978, CST), CDKN2A (1:1000, ab108349, ABCAM), CDKN1B (1:1000, #3686, CST), CDKN1A (1:1000, #2947, CST), SQSTM1

(2) Repurposing acetyldigitoxin as a potential EZH2 inhibitor for non-small cell lung cancer: a computational and experimental approachJ Comput Aided Mol DesApril 6, 2026Xiang Ji, Xiyan Wang, Ting Xiu, Min Gao, Degan Lu(1:1000, #5023), anti-Bcl-2 (1:1000, #15,071), anti-Caspase-3 (1:1000, #9662), anti-Cyclin D1 (1:1000, #2978), anti-H3K27me3 (1:1000, #9733) and anti-Histone H3 (total H3; 1:1000, #4499) for normalization, and

(3) Transcriptional control of PPP2CB by YAP1 and TEAD1 mediates AMPK inhibition and mTORC1 activation in vascular smooth muscle cellsiScienceMarch 20, 2026Sanjana Kumariya, Joanna Stuck, Arturo Grano de Oro, Islam Osman(Thermo Fisher Scientific, cat. #: PA5-17728, rabbit, 1:1000), Cyclin D1 (Cell signaling Technology, cat. #: 2978, rabbit, 1:1000), PCNA (Thermo Fisher Scientific, cat. #: MA511358, mouse, 1:1000), p27Kip1 (Cell signaling Technology

(4) SIRT1 mediates brain metabolic and developmental consequences of methionine synthase deficiency in inborn errors of cobalamin metabolismCell Reports MedicineMarch 17, 2026Karim Matmat, Ziad Hassan, Grégory Pourié, Yaser Atlasi, Snehaa Vivienne Seal, Manon Jeandel, Carole Arnold, Sachin Luharia, Rémy Umoret, Ramia Safar, et al.Antibody,Santa Cruz,Cat#Sc-788; RRID: AB_631277 Anti-CyclinD1 (92G2) Monoclonal Antibody,Cell Signaling,Cat#2978; RRID: AB_2259616 Anti-Pcna (PC10) Monoclonal Antibody,Cell Signaling,Cat#2586S; RRID: AB_2160343 Anti-Neurod1

(5) Proteomics-Based Studies Identify the Metallothionein-2A as a Potential Target of Thioxo-Tetrahydropyrimidine Derivatives in Hepatocellular CarcinomaACS OmegaMarch 10, 2026Kittisak Sripha, Nichawadee Sandech, Meng Chieh Yang, Sucheewin Krobthong, Chatchakorn Eurtivong, Boonta Chutvirasakul, Pakjira Patchim, Pattarawit Rukthong, Korbtham Sathirakul, Kodcharat Cheevapruk, et al.cat. #5625; 1:2,000), CDK4 (Cell signaling, cat. #12790; 1:2,000), Cyclin D1 (Cell signaling, cat. #2978; 1:2,000), GAPDH (Cell signaling, cat. #2118; 1:10,000) overnight at 4 °C. Then, the membrane was washed

(6) Targeting the RXR Pathway for the Prevention of Triple Negative Breast CancerCancer Prevention ResearchMarch 3, 2026Cassandra L. Moyer, Jamal L. Hill, Darian Coleman, Amanda Lanier, Yanxia Ma, Xiaoqian Liu, Jitesh Kawedia, Alejandro Contreras, Vidyasagar Vuligonda, Michelle I. Savage, et al.Cell Signaling Technology, cat. #9664 (also 9664P), RRID: AB_2070042], cyclin D1 (Cell Signaling Technology, #2978, RRID: AB_2259616), and CD8a (Abcam, Ab217344, RRID: AB_2890649. 4). Images were acquired with Aperio

(7) ALKBH5 promotes ovarian cancer progression by activating Notch2 signalingBiological Procedures OnlineMarch 3, 2026Yanying Liu, Huafeng Luo, Luhong Li, Ziao Gao, Qian Wang, Hao Liu, Ruiyun Wu, Cong PengCell Signaling Technology), anti-JAG2 antibody (#3230, Cell Signaling Technology), anti-CCND1 antibody (#2978, Cell Signaling Technology), anti-c-myc antibody (#9402, Cell Signaling Technology), anti-Hes1 antibody

(8) Targeting NAT10 alleviates colonic senescence and elderly-onset colitis by disrupting N4-acetylation of DYRK1ANature CommunicationsMarch 1, 2026Jingyu Chen, Meng Xue, Shuyi Mi, Anbo Fu, Wenwen Chen, Yuhao Sun, Shenglong Xia, Qiwei Ge, Jiakai Luo, Qiao Yu, et al.10883-1-AP and 28416-1-AP USA), Occludin (1:1000, Proteintech, 27260-1-AP, USA), Cyclin D1 (1:1000, CST, #2978, USA), γ-H2AX (1:1000, ABclonal Technology, AP0687, MA, USA), DYRK1A(1:1000, Bioss, bs-11834R, China),

(9) Antioxidant and Anti-Aging Effects of Porphyra-334 Produced from Saccharomyces cerevisiae in Human Skin ModelsMar DrugsFebruary 28, 2026Soeun Park, Saitbyul Park, Nok Hyun Park, Eun-Soo Lee, Kilsun Myoung, Heung-Soo Baek, Jaewoo Jang, Sang-Jip Nam, Jaeyoung Ko, Chang Seok Leeagainst c-Myc (1:2000; 10828-1-AP; Proteintech Group, Inc., Rosemont, IL, USA), Cyclin D1 (1:1000; 2978S; Cell Signaling Technology), Ki-67 (1:500; ab16667; Abcam), Bax (1:5000; ab32503; Abcam), Caspase-9

(10) Neural stem cells transplantation combined with ethyl stearate promotes the activation of quiescent NSCs and improves PD rats motor behaviorAnimal Models and Experimental MedicineFebruary 26, 2026Xiaoxiao Yang, Haisheng Ma, Lan Yi, Qi Zheng, Sen Ye, Jun Zhong, Xican Li, Hui Li, Caixia Lianti‐EphB2(1:1000, CST, #83029), anti‐Nestin (1:1000, Absin, abs137231), anti‐CyclinD1(1:1000, CST, #2978), anti‐p‐AKT(1:1000, CST, #4046), anti‐AKT(1:1000, CST, #4691), anti‐GAPDH (1:1000, CST, #2118). They

(11) Clinical and Functional Characterization of PDE1A as a Wnt/β-Catenin-Linked Biomarker of Progression and Platinum Resistance in Epithelial Ovarian CancerOncology ResearchFebruary 24, 2026Gwan Hee Han, Hee Yun, Joon-Yong Chung, Jae-Hoon Kim, Hanbyoul Choprimary antibodies at the following dilutions: E-cadherin (CST #3195), Slug (CST #9585), Cyclin D1 (CST #2978), β-catenin (CST #8482), P-β-catenin (Ser33/37/Thr41, CST #9561), and c-Myc (sc-40; Santa Cruz, CA,

(12) LINC01857 promotes clear cell renal cell carcinoma progression by scaffolding DNMT1 to suppress WIF1 expressionScientific ReportsFebruary 10, 2026Wei Xiang, Lei Lyu, Fuxin Zheng, Chuanhua Zhang, Jingdong Yuan(CST, #13116, 1:1000), c-Myc (CST, #18583, 1:1000), β-catenin (CST, #9562, 1:1000), cyclin D1 (CST, #2978, 1:1000), DNMT1 (Abcam, ab320817, 1:1000), and WIF1 (Abcam, ab155101, 1:1000). Subsequently, secondary

(13) VGLL4 modulates Paneth cells and sustains intestinal homeostasisEMBO ReportsFebruary 2, 2026Haoen Zhang, Zuoyun Wang, Xiaodong Wang, Wentao Yu, Guoying Zhang, Haijiao Zhang, Yi Lu, Yang Sun, Tiantian Lu, Xiaoyu Li, et al.,Cell Signaling Technology,"Cat# 39141, RRID:AB_2650511" Rabbit anti-CyclinD1,Cell Signaling Technology,"Cat#2978, RRID:AB_2259616" Rabbit anti-Lysozyme,Dako Denmark,"Cat#A0099, RRID:AB_2341230" Mouse anti-β-Tubulin,DSHB,"Cat#E7,

(14) VPS35 Deficiency Markedly Reduces the Proliferation of HEK293 CellsGenes (Basel)January 31, 2026Sujin Lee, Soojin Park, Hyewon Bang, Sun-Uk Kim, Young-Ho Park, Gabbine Wee, Unbin Chae, Ekyune Kim(PARP; 9542S; 1:3000), anticytochrome C (11940S; 1:1000), anti-CDK4 (12790S; 1:2000), anti-cyclinD1 (2978S; 1:3000), anti-Drp1 (8570S; 1:3000), and anti-pDrp1 (S616) (3455S; 1:1000) (all from Cell Signaling Technology

(15) EZH2 directs HER2+ breast cancer progression through the modulation of epithelial plasticityEMBO ReportsJanuary 28, 2026Linshan Liu, Ellie J Massey, Dongmei Zuo, Alain Pacis, Mert Demirdizen, Elizabeth Podleszanski, Jessica Cinkornpumin, Yu Gu, Hailey Proud, Virginie Sanguin-Gendreau, et al.anti-Ki67,Cell Signaling,12202 Mouse anti-PCNA,Cell Signaling,2586 Rabbit anti-Cyclin D1,Cell Signaling,2978 Rabbit anti-LaminB1,Cell Signaling,17416 Rabbit anti-p-Rb (S807/S811),Cell Signaling,8516 Rabbit

(16) Homoisoflavanone Delays Colorectal Cancer Progression via DNA Damage‐Induced Mitochondrial Apoptosis and Parthanatos‐Like Cell DeathAdvanced ScienceJanuary 28, 2026Hongjie Fan, Huzi Zhao, Pei Zhang, Pengfei Yu, Yunfei Ji, Gang Chen, Hongli Jin, Yanfang Liu, Jin Liu, Zhe‐Sheng Chen, et al.CST), cleaved PARP (9541, CST), P21 (2947, CST), P53 (2527, CST), Cyclin A2 (91500, CST), Cyclin D1 (2978, CST), CDK1 (bs‐1341R, Bioss), CDK2 (bs‐10726R, Bioss), CDK7 (bs‐0569R, Bioss), AKT (4691, CST), p‐AKT

(17) Paeonia lactiflora Callus-Derived Polynucleotides Enhance Collagen Accumulation in Human Dermal FibroblastsJournal of Functional BiomaterialsJanuary 22, 2026Soyoung Hwang, Seunghye Park, Jin Woo Lee, Mira Park, Le Anh Nguyet, Yongsung Hwang, Keunsun Ahn, Hyun-young Shin, Kuk Hui SonUK), CREB (ab32096, 1:1000, Abcam), phospho-CREB (Ser133; ab32096, 1:1000, Abcam), Cyclin D1 (96G2; #2978, 1:1000, Cell Signaling Technology), RB (SC-74570, 1:500, Santa Cruz Biotechnology, Dallas, TX, USA),

(18) Hepatic adaptation to chronic metabolic stress primes tumorigenesisCellJanuary 22, 2026Constantine N. Tzouanas, Jessica E.S. Shay, Marc S. Sherman, Adam J. Rubin, Benjamin E. Mead, Tyler T. Dao, Junyan Tao, Brandon M. Lehrich, George Eng, Jeffrey Patterson-Fortin, et al.(1:1000, BD Biosciences, #610154), rabbit monoclonal anti-Cyclin D1 (1:1000, Cell Signaling Technology, #2978), rabbit monoclonal anti-vinculin (1:1000, Cell Signaling Technology, #13901) followed by horseradish

(19) Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recoveryMolecular Medicine ReportsJanuary 13, 2026Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong ZhaoLtd.",,, β-catenin,Abcam,ab305261,WB,"1:1,000" HNF4α,Santa Cruz,sc-101059,WB,1:100 ,"Biotechnology, Inc.",,, Cyclin D1,CST Biological,2978S,WB,"1:1,000" ,"Reagents Co., Ltd.",,, GAPDH,HUABIO,HA721136,WB,"1:5,000" β-actin,HUABIO,HA722023,WB,"1:20,000" Goat

(20) Influence of stage-specific and location-related intratumoral microbiota on prognosis and metabolic reprogramming in non-small cell lung cancerFrontiers in ImmunologyJanuary 5, 2026Yuwei Zhao, Zhuang Tong, Lin Liu, Rongjie Yang, Zhongfeng Chen, Zheng WangCell Signaling Technology (CST), USA, 1:1000 dilution), CDK-6 (3136, CST, USA, 1:1000 dilution), and Cyclin D1 (2978, CST, USA, 1:1000 dilution). In the case of metastasis-related proteins, we selected the primary antibodies

Write a Review

(1)

9/19/2018Decent Antibody for Cyclin D1 Rebecca WatesThis study seeks to validate functional genomic mutations observed in human cancer cells resistant to drug therapies. This antibody was used in Western blotting of human cancer cell lysates.
(1)

8/28/2017Cyclin D1 Antibody For Western Blotting Ab GThe antibody is specific for Cyclin D1 and is user-friendly. No optimization is necessary for applying this antibody to western blotting.
(1)

8/2/2016Good Antibody For Western Blotting Shikha SainiCyclin D1 is a marker of G0-G1 cell cylce arrest. We treated our cells with a known drug and observed its effect on cell cycle.
(1)

5/31/2016Excellent Cyclin D1 antibody for Immunodetection in human cell Raj KumarAim of the study was to test the time course effect of specific growth factor on cyclin D1 study state levels in human smooth muscle cells. Cell line grown in complete media was growth arrested, ... Read Review

Cyclin D1 (92G2) Rabbit mAb

Cyclin D1 (92G2) Rabbit mAb from Cell Signaling Technology

Description

Questions and Answers

Cell Signaling Technology

Citations (1054)

Reviews

Cyclin D1 (92G2) Rabbit mAb from Cell Signaling Technology

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map