Survivin (71G4B7) Rabbit mAb 2808S from Cell Signaling Technology

Product Specs
ItemSurvivin (71G4B7) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number2808S
Quantity100 µl
ApplicationsW, W-S, IP, IHC-P, IF-IC, FC-FP
ReactivityH, M, R, Mk
TargetSurvivin
HostRabbit
NCBI Gene AliasesAPI4, EPR-1
ClonalityMonoclonal
NCBI Full Gene Namebaculoviral IAP repeat containing 5
Research AreaApoptosis
IsotypeIgG
Clone71G4B7
Molecular Weight16

Questions and Answers

Can this antibody be used for Western blotting in cancer research?

Yes, the Survivin (71G4B7) Rabbit mAb has been utilized in Western blotting to detect total Survivin protein levels in various studies, including its role in cancer cell proliferation and apoptosis regulation.

What species does this antibody react with, and has it been used in studies involving human tissues?

The Survivin antibody is reactive with mouse, rat, and human tissues. It has been cited in numerous studies involving human cancer cells, demonstrating its applicability in research focused on human cancer biology.

Is there any evidence of this antibody being used in immunohistochemistry for tumor analysis?

Yes, the Survivin antibody has been employed in immunohistochemistry to analyze tumor samples, as indicated by its use in studies examining the expression of Survivin in various cancer types, including glioblastoma and colorectal cancer.

How has this antibody contributed to understanding the mechanisms of cancer cell survival?

The Survivin antibody has been referenced in studies that explore its role in inhibiting apoptosis and promoting cell survival in cancer cells, highlighting its significance in the regulation of the apoptotic pathway and its potential as a therapeutic target in cancer treatment.

Cell Signaling Technology

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Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Hemidesmosomes and Notch signaling regulate epidermal differentiation via delaminationDevelopmentAugust 15, 2026Juliet S. King, Kendall J. Lough, Scott E. Williamsphotobleaching. The following antibodies were used: survivin (rabbit mAb 71G4B7, Cell Signaling Technology, 2808S, AB_2063948; 1:500), LGN (rabbit, Millipore ABT174, AB_2916327; 1:2000), phospho-histone H3 (rat, Abcam

(2) Age-Dependent Alterations of Chromosomal Passenger Complex Members During Implantation and Decidualization in the Mouse UterusAging CellApril 23, 2026Ezgi Golal, Cemre Nur Balci, Nuray Acaranti‐Aurora Kinase B (Abcam #ab2254) at 1:100 dilution, rabbit polyclonal anti‐Survivin (Cell Signaling #2808S) at 1:50 dilution, rabbit polyclonal anti‐Borealin (MyBioSource #MBS127771) at 1:100 dilution, and rabbit

(3) In Silico and In Vitro Investigation of Apoptosis-Mediated Antiproliferative Activity of Capsaicin and Alpha-Lipoic Acid Against Prostate Cancer CellsCurr Issues Mol BiolApril 4, 2026Ogunc Meral, Burcu Menekse Balkan, Dilek Nur Bestil, Serkan Sayiner, Deniz Ceylanli, Sare Uyurca, Sinem Pehlivan, Guzin Ozkurt, Gorkem Kismali, Tevhide Seland then incubated with the corresponding primary antibodies at 4 °C overnight. Survivin (Cat. No: 2808, Cell Signalling Technology, Danvers, MA, USA, 1:1000 dilution) and bax (Cat. No: 2772, Cell Signalling

(4) Integrative analysis reveals the role of SUMOylation-related patterns in shaping the tumor microenvironment and predicting treatment sensitivity of colorectal cancerTranslational Cancer ResearchMarch 31, 2026Gaojian Cao, Sen Zhang, Hao Zhong, Jie Yu, Xiexiao Cai, Xiangwei Huang, Mengqin Yu, Naijipu Abuduaini, Jingyi Liu, Wanyu Wang, et al.were incubated with primary antibodies overnight at 4 °C (Cell Signaling Technology, Danvers, MA, USA; 2808, O15392), followed by a biotinylated secondary antibody for 30 min at 37 °C. Signal was developed with

(5) Effect of anticancer activity of aripiprazole main metabolite OPC-14857 on malignant glioblastomaPLoS OneMarch 13, 2026Shuhei Nakao, Yuki Uemichi, Shuji Nagano, Miyuki Mabuchi, Shiho Ohmori, Daichi Enomoto, Takehiko Ueyama, Tadashi Shimizuanti-Akt, anti-survivin, anti-Src, anti-p53, anti-caspase-3 (Cell Signaling Technology, 4691, 4060, 2808, 2123, 30313, 9662) and anti-GAPDH (cytosolic marker, Proteintech) antibody using immunoreaction enhancer

(6) Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107Molecular OncologyMarch 1, 2026Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, et al.#9541; 1:500), SLFN11 (Cell Signaling #34858), OAS1 (Cell Signaling #14498), BIRC5 (Cell Signaling # 2808), BCL2 (Cell Signaling #15071), FANCD2 (Cell Signaling #16323), and α‐Tubulin (Sigma‐Aldrich, Steinheim,

(7) Cancer-associated fibroblasts promote osimertinib resistance in non-small cell lung cancer cells via METTL1-mediated NET1 m7G modificationCell Death & DiseaseFebruary 21, 2026Yongmei Qian, Zhiyuan Gong, Yidan Jia, Qicheng Zhang, Limin Cao, Bingbing Li, Jiayi Zhang, Min Wang, Xiang Wu, Ke Xu(1:1000 dilution) were purchased from Proteintech Group (Rosemont, IL). Antibodies against Survivin (#2808), Caspase-3 (#9662), Cleaved-caspase-3 (#9661), AKT (#4691), p-AKT (#4060), p65 (#4764), p-p65 (#3033)

(8) Spatial single-cell analysis reveals tumor microenvironment signatures predictive of oral cavity cancer outcomeCell Reports MedicineFebruary 17, 2026Joni Näsiaho, Linda Nissi, Sami Ventelä, Heikki Irjala, Marko SalmiRetrieval). Predetermined optimal dilutions of anti-TYMS (#9045, CST, 1:200 dilution), anti-BIRC5 (#2808, CST, 1:200 dilution), and anti-BST2 (#95940, CST, 1:200 dilution) were used as primary antibodies (one

(9) Pseudolaric acid B promotes lung cancer cells ferroptosis depending on JNK/ERK-mediated upregulation of survivinScientific ReportsFebruary 11, 2026Yuqiong Li, Changping Yu, Shufeng Yang, Buqing Sai, Xin Chen, Ping Chen, Huoyan Liu, Jie Jia, Yu Zhang, Ruifen Sun, et al.Bioscience, #310091), c-IAP1 (CST, #7065), c-IAP2 (CST, #3130), XIAP (CST, #2045), Survivin (CST, #2808), SLC7A11 (Zen Bioscience, #R382036༉, GPX4 (Zen Bioscience, #R24461), GAPDH (CST, #2118). Quantitative real-time polymerase chain reaction

(10) Circular RNA circATM binds PARP1 to suppress Wnt/β-catenin signaling and induce cell cycle arrest in gastric cancer cellsJournal of Advanced ResearchFebruary 1, 2026Xiaohui Zhu, Xiaojing Zhang, Ying Qin, Yang Chen, Xianling Feng, Shiqi Deng, Fan Hu, Yuan Yuan, Xiaonuan Luo, Kaining Du, et al.PARP (Cell Signaling Technology Cat# 9542, RRID:AB_2160739), Survivin (Cell Signaling Technology Cat# 2808, RRID:AB_2063948), Cox2 (Cell Signaling Technology Cat# 4842, RRID:AB_2084968), APC (Cell Signaling Technology

(11) Dual epigenetic and nuclear export inhibition by chidamide and selinexor in high grade B-cell lymphomas via survivin and PI3K/AKT inhibitionClinical EpigeneticsJanuary 26, 2026Jiazhen Lin, Xinguo Zhuang, Shuman Jia, Hui Zhou, Dongmei Qin, Jie Zhou, Bozhang Chen, Mingxin Zhuang, Bing Xu, Jie ZhaHubei, China). For the detection of various proteins, a range of primary antibodies were used. Survivin (2808), FOXO1(2880), FOXO3a(12829) and CyclinA2 (4656T) antibodies were obtained from Cell Signaling Technology

(12) RNA‐Micelles as Self‐Assembling Structures for Efficient Co‐Delivery of Synergistic siRNA and Nucleoside Analogues to Treat CRC Lung MetastasisAdvanced Functional MaterialsJanuary 20, 2026Kai Jin, Piotr Rychahou, Daniel W. Binzel, B. Mark Evers, Peixuan Guoincubated with survivin (71G4B7) rabbit monoclonal antibody (Cell Signaling Technology, Danvers, MA, #2808, 1:500) overnight at 4°C, washed with PBS, and incubated with VectaFluor Anti-Rabbit secondary antibodies

(13) Disrupting CDK9 activity suppresses triple-negative breast cancer and is enhanced by EGFR InhibitionCell Oncol (Dordr)January 8, 2026Vera E. van der Noord, Ronan P. McLaughlin, Jessica S. Karuntu, Jichao He, A. Mieke Timmermans, Sunita K. C. Basnet, Yi Long, Sarah Al Haj Diab, Solomon Tadesse, Natalie Proost, et al.phospho-RNAPII Ser2 (CST #13499), phospho-RNAPII Ser5 (CST #13523), RNAPII (CST #2629), Survivin (CST #2808), BCL-xL (CST #2764), XIAP (CST #2045), MCL1 (CST #5453), γ-H2AX (S139; CST #2577) and tubulin (Sigma

(14) Loss of Brg1 and Pten in Pancreatic Ductal Cells Forms Intraductal Tubulopapillary Neoplasm via the YAP/TAZ PathwayCellular and Molecular Gastroenterology and HepatologyJanuary 1, 2026Kei Iimori, Akihisa Fukuda, Munemasa Nagao, Sho Matsuyama, Munehiro Ikeda, Yoko Masui, Shinnosuke Nakayama, Naoki Aoyama, Kenta Mizukoshi, Munenori Kawai, et al.,Cell Signaling,1:200,#4060 BRG1,Abcam,1:200,ab110641 CK19,Abcam,1:200,ab52625 Ki67,BioLegend,1:100,652402 PDX1,Abcam,1:10000,ab47308 SOX9,Millipore,1:1000,AB5535 HNF1β,Proteintech,1:200,12533-1-AP TAZ,CST,1:400,#72804 CYR61,CST,1:50,#39382 BIRC5,CST,1:400,#2808 CTGF,Abcam,1:200,AB6992 ANKRD1,Sigma-Aldrich,1:200,MABS1228 BRM,CST,1:200,#11966S ARID1A,Abcam,1:200,ab182560 PBRM1,Bethyl,1:500,A301-591A Primary

(15) Cephalochromin Effects in Triple-Negative Breast Cancer Cells: Apoptosis Induction and Modulation of Survival PathwaysJ Nat ProdDecember 26, 2025Isabelle Diccini, Natália Sudan Parducci, Bruna Oliveira de Almeida, Victor Farinella, Patrick Castilho Dos Santos, Livia Bassani Lins de Miranda, Sabrina Mendes Botelho, Keli Lima, Jorge Antonio Elias Godoy Carlos, Anali Del Milagro Bernabe Garnique, et al.UK (Syngene). The following antibodies were used: PARP1 (no. 9542), γH2AX (no. 9718), survivin (no. 2808), SQSTM1/p62 (no. 88588), LC3B (no. 2775), GAPDH (no. 5174), and α-tubulin (no. 2144) were obtained

(16) Network Pharmacology and Experimental Validation Reveal Aidi Injection Suppresses Prostate Cancer via EGFR Inhibition and STAT3-Mediated ApoptosisBiol Proced OnlineDecember 22, 2025Ganhua You, Chen Qian, Xiaoyue Chen, Qunying An, Jukun Song, Yuehai Xiaoof Bcl-xl (catalogue, #2764S), PCNA (catalogue, #13110S), Bax (catalogue, #2772S), BIRC5(catalogue, #2808S), β-actin (catalogue, #4967S) and P-STAT3 (Thy705) (catalogue, #9145s) were purchased from the Cell Signaling Technology

(17) An mTOR-Stat3-Stathmin pathway controls centrosome and microtubule dynamics for oocyte polarizationCurrent BiologyDecember 15, 2025Amal Shawahny, Yoel Bogoch, Neta Hart, Yaniv M. ElkoubyStat3 (124H6) Mouse mAb,Cell Signaling Tech,CST-9139; PRID: AB_331757 Rabbit anti-survivin,Cell Signaling Tech,CST- 2808; PRID: AB_2063948 "Goat anti-Mouse IgG1 Cross-Adsorbed Secondary Antibody, Alexa Fluor™ 594",Molecular Probes

(18) Comprehensive analysis of BIRC5: from pan-cancer analysis to experimental validationBMC CancerDecember 8, 2025Guoliang Liao, Jiekun Qian, Shijie Wei, Xin Yan, Qing Liu, Qinzhao Huang, Yuxing Lin, Guobing Xu, Bin Zheng, Chun Chen, et al.(Proteintech; Cat No: 66009–1-Ig) and BIRC5 (Cell Signaling Technology; Survivin (71G4B7) Rabbit mAb #2808) as the primary antibodies. The following day, we washed the membranes three times with TBST and incubated

(19) Discovery of a novel small molecule degrader of wild type and mutant estrogen receptors using DNA encoded librariesnpj Breast CancerNovember 12, 2025Anil Kumar Devakrishnan, Chandrashekhar Madasu, Yong Wang, Ramkumar Modukuri, Kurt M. Bohren, Kevin R. MacKenzie, Damian W. Young, Suzanne A. W. Fuqua, Martin M. Matzuk, Murugesan Palaniappananti-cyclin D1 (Invitrogen, Cat. # MA5-42676), anti-survivin (Cell Signaling Technology (CST), Cat. # 2808S), anti-E2F1 (CST, Cat. # 3742), anti-TFF1 (CST, Cat. # 15571S), anti-cleaved PARP (CST, Cat. # 5625S),

(20) Cellular and Molecular Effects of Targeting the CBP/β-Catenin Interaction with PRI-724 in Melanoma Cells, Drug-Naïve and Resistant to Inhibitors of BRAFV600 and MEK1/2CellsOctober 31, 2025Anna Gajos-Michniewicz, Michal Wozniak, Katarzyna Anna Kluszczynska, Malgorzata CzyzNext, western blotting was conducted as reported earlier [43]. Primary antibodies detecting survivin (#2808), p21 (#2947), cyclin D1 (#92G2), c-Myc (#E5Q6W), and MITF (#12590) were obtained from Cell Signaling Technology

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(1)

6/29/2024Survivin mAb From Cell Signaling Was Used as a Marker of Cancer Process After DMAG-17 Chemotherapy Treatment. Ksenia NovototskayaActivation of endogenous retrotransposons frequently occurs in cancer cells and contributes to tumor genomic instability. To test whether inhibition of retrotranspositions has an anticancer effect, we... Read Review
(1)

8/25/2017Survivin Antibody For Western Blotting Ab GThis is a great antibody for detecting survivin by western blotting. Non-specific bands are not evident.
(1)

12/21/2016Expression of Survivin in HEK293 Cells Arul ManiSurvivin is a member of the inhibitor of apoptosis (IAP) family and it functions to inhibit caspase activation which leads to negative regulation of apoptosis or programmed cell death. It has been ... Read Review
(1)

11/11/2015Survivin Expression in Mouse T Cells Jesus BanuelosThe aim of the research was to determine the levels of Survivin in unstimulated and stimulated mouse T cells. T cells were stimulated for 24h with anti-CD3/28 Survivin levels were measured by Western... Read Review

Survivin (71G4B7) Rabbit mAb

Survivin (71G4B7) Rabbit mAb from Cell Signaling Technology

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Survivin (71G4B7) Rabbit mAb from Cell Signaling Technology

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