EPLIN (20) Antibody sc-136399 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemEPLIN (20) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-136399
ClonalityMonoclonal
ApplicationsWB, IP, IF, IHC(P)
NCBI Gene AliasesLDLCQ8, SREBP3, Eplin, EPLIN
Conjugate/TagUnconjugated
Reactivitymouse, rat, human, canine
Quantity200 µg/ml
Clone20
Antibody TypePrimary Antibodies
NCBI Full Gene NameLIM domain and actin binding 1
TargetEPLIN
Hostmouse
FormatPurified
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) CDK1-mediated phosphorylation of EPLIN is crucial for mitotic spindle positioningCommunications BiologyJune 4, 2026Jia-Rong Fan, Yun Hsieh, Chien-Chen Lai, Hong-Chen Chenactin and membrane dynamics remains to be studied. Methods Antibodies and reagents The anti-EPLIN (sc-136399, for IF 1:150 and for WB 1:1000) and anti-cyclin B1 (sc-245, 1:1500) antibodies were purchased from

(2) LIMA1-alpha staining predicts curative intent surgery response in HPV negative head and neck cancerEMBO molecular medicineAugust 1, 2025Qiao X, Routila J, Tienhaara M, Irjala H, Santhi PP, Huusko T, Nissi L, Paatero I, Lehtinen N, Rantala J, et al.Following antibodies were used for IHC: LIMA1 (HPA023871 (1:1000 Rabbit polyclonal, Atlas Antibodies)) or (sc-136399 (1:1000 mouse monoclonal, Santa Cruz Biotechnology)), LIMA1-beta (RB581 (1:1000 rabbit polyclonal, custom-made

(3) EPLIN-β is a novel substrate of ornithine decarboxylase antizyme 1 and mediates cellular migrationJournal of cell scienceJune 15, 2023Li D, Neo SP, Gunaratne J, Sabapathy K.(St. Louis, MO, USA); anti-FLAG (PA1-984B, lot WG319616) from Thermo Fisher Scientific; anti-EPLIN (sc-136399, lot H2117), anti-Myc (9E10) (sc-40, lot D0419) and anti-Mdm2 (sc-965, lot F2718; 1:200 for western blotting

(4) EPLIN, a Putative Tumour Suppressor in Colorectal Cancer, Implications in Drug ResistanceInternational journal of molecular sciencesDecember 3, 2022Zeng J, Sanders AJ, Ye L, Hargest R, Ruge F, Jiang WG.and quantified before they were precipitated with EPLIN antibody (immunoglobulin G (IgG) monoclonal, Sc- 136399, Santa Cruz Biotechnology, Inc. Dallas, TX, USA). Samples were then sent to Kinexus Bioinformatics Ltd.,

(5) Src activation in lipid rafts confers epithelial cells with invasive potential to escape from apical extrusion during cell competitionCurrent biology : CBAugust 22, 2022Kajiwara K, Chen PK, Abe Y, Okuda S, Kon S, Adachi J, Tomonaga T, Fujita Y, Okada M.

(6) Rab40-Cullin5 complex regulates EPLIN and actin cytoskeleton dynamics during cell migrationThe Journal of cell biologyJuly 5, 2021Linklater ES, Duncan ED, Han KJ, Kaupinis A, Valius M, Lyons TR, Prekeris R.anti-EPLIN (WB 1:1,000, IF 1:100, 50311; Cell Signaling Technology), anti-EPLIN (WB 1:1,000, IF 1:100, sc-136399; Santa Cruz Biotechnology), anti-EPLIN (WB 1:1,000, immunoprecipitation [IP] 1 μg/1 mg lysate, immunohistochemistry [IHC

(7) High resolution analysis of the intracellular proteome of cervical cancer cell lines unveils novel regulators of cervical carcinogenesisOncology reportsOctober 1, 2019Pappa KI, Lygirou V, Kontostathi G, Makridakis M, Vougas K, Sfakianakis A, Daskalakis G, Zoidakis J, Anagnou NP.washed with TBS‑Tween 0.1% v/v successively for 15, 5 and 5 min, and the primary antibodies: LIMA1 (sc‑136399; dilution, 1:200; Santa Cruz Biotechnology, Inc., Dallas, TX, USA), PON2 (sc‑373981; dilution, 1:100;

(8) Accumulation of the myosin-II-spectrin complex plays a positive role in apical extrusion of Src-transformed epithelial cellsGenes to cells : devoted to molecular & cellular mechanismsNovember 1, 2018Takagi M, Ikegawa M, Shimada T, Ishikawa S, Kajita M, Maruyama T, Kamasaki T, Fujita Y.

(9) ADAM-like Decysin-1 (ADAMDEC1) is a positive regulator of Epithelial Defense Against Cancer (EDAC) that promotes apical extrusion of RasV12-transformed cellsScientific reportsJune 25, 2018Yako Y, Hayashi T, Takeuchi Y, Ishibashi K, Kasai N, Sato N, Kuromiya K, Ishikawa S, Fujita Y.anti-filamin (F6682) antibody was purchased from Sigma-Aldrich. Rabbit anti-p65 (sc-109) and mouse anti-EPLIN (sc-136399) antibodies were from Santa Cruz Biotechnology. Mouse anti-ADAMDEC1 antibody was kindly provided by

(10) The paxillin-plectin-EPLIN complex promotes apical elimination of RasV12-transformed cells by modulating HDAC6-regulated tubulin acetylationScientific reportsFebruary 1, 2018Kasai N, Kadeer A, Kajita M, Saitoh S, Ishikawa S, Maruyama T, Fujita Y.anti-α-tubulin (YOL1/34) antibody was from Abcam. Rabbit anti-paxillin (sc-5574) and mouse anti-EPLIN (sc-136399) antibodies were from Santa Cruz Biotechnology. Mouse anti-paxillin (clone 349) antibody was from BD

(11) Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changesNature cell biologyMay 1, 2017Kon S, Ishibashi K, Katoh H, Kitamoto S, Shirai T, Tanaka S, Kajita M, Ishikawa S, Yamauchi H, Yako Y, et al.this study; goat anti-LDHA (sc-27230), mouse anti-Tom20 (sc-17764 clone F10) and mouse anti-EPLIN (sc-136399 clone 20) antibodies from Santa Cruz Biotechnology, mouse anti-myc (05-724 clone 4A6) and mouse anti-β-actin

(12) Rab5-regulated endocytosis plays a crucial role in apical extrusion of transformed cellsProceedings of the National Academy of Sciences of the United States of AmericaMarch 21, 2017Saitoh S, Maruyama T, Yako Y, Kajita M, Fujioka Y, Ohba Y, Kasai N, Sugama N, Kon S, Ishikawa S, et al.

(13) Plectin is a novel regulator for apical extrusion of RasV12-transformed cellsScientific reportsMarch 10, 2017Kadeer A, Maruyama T, Kajita M, Morita T, Sasaki A, Ohoka A, Ishikawa S, Ikegawa M, Shimada T, Fujita Y.(YOL1/34) and rabbit anti-caveolin (610059) antibodies were obtained from Abcam. Mouse anti-EPLIN antibody (sc-136399) was from Santa Cruz Biotechnology. Mouse anti-FLAG antibody (M2) was from Sigma-Aldrich. Alexa-Fluor-568-

(14) Proteomic analysis reveals novel common genes modulated in both replicative and stress-induced senescenceJournal of proteomicsOctober 14, 2015Succoio M, Comegna M, D'Ambrosio C, Scaloni A, Cimino F, Faraonio R.

(15) Binding to F-actin guides cadherin cluster assembly, stability, and movementThe Journal of cell biologyApril 1, 2013Hong S, Troyanovsky RB, Troyanovsky SM.clone HECD1 (Invitrogen); rabbit anti-Dendra2 (Evrogen); mouse anti-ZO1 (BD); and mouse anti-Eplin (sc-136399; Santa Cruz Biotechnology, Inc.). Alexa Fluor 555 phalloidin was purchased from Invitrogen. For the

(16) "Targeting lysine-specific demethylase 1 (KDM1A/LSD1) impairs colorectal cancer tumorigenesis by affecting cancer cells stemness, motility, and differentiation"Cell death discoveryJanuary 1, 0001"Antona A, Leo G, Favero F, Varalda M, Venetucci J, Faletti S, Todaro M, Mazzucco E, Soligo E, Saglietti C, et al."Biotechnology, Dallas, TX, USA), anti-Villin (sc-58897; Santa Cruz Biotechnology, Dallas, TX, USA), anti-LIMA (sc-136399; Santa Cruz Biotechnology, Dallas, TX, USA), anti-CDH17 (MA5-29135; Thermo Fisher Scientific, Waltham,

(17) Disruption of nucleocytoplasmic trafficking as a cellular senescence driverExperimental & molecular medicineJanuary 1, 0001"Park JH, Ryu SJ, Kim BJ, Cho HJ, Park CH, Choi HJC, Jang EJ, Yang EJ, Hwang JA, Woo SH, et al."anti-CRM1 (sc-5595), anti-RCC1 (sc-1162), anti-RanBP1 (sc-1160), anti-Myo6 (sc-393558), anti-EPLIN (sc-136399), and anti-HEXB (sc-376781) antibodies from Santa Cruz Biotechnology; anti-p21 (#554228), anti-Rb (#554136),

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EPLIN (20) Antibody

EPLIN (20) Antibody from Santa Cruz Biotechnology, Inc.

Santa Cruz Biotechnology, Inc.

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EPLIN (20) Antibody from Santa Cruz Biotechnology, Inc.

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