PCB (H-2) Antibody sc-271493 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPCB (H-2) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-271493
NCBI Gene AliasesPcb, Pc, PCB
ClonalityMonoclonal
ApplicationsWB, IP, IF, ELISA
Conjugate/TagUnconjugated
Reactivitymouse, rat, human
CloneH-2
Antibody TypePrimary Antibodies
Quantity200 µg/ml
Hostmouse
NCBI Full Gene Namepyruvate carboxylase
TargetPCB
FormatPurified
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Beta cell dysfunction occurs independently of insulitis in type 1 diabetes pathogenesisCell reportsSeptember 23, 2025Huber MK, Widener AE, Cuaycal AE, Smurlick D, Butterworth EA, Lenchik NI, Chen J, Beery M, Hiller H, Verney E, et al.,Santa Cruz Biotechnology,Cat# sc-515102 Clone C-2 RRID: AB_2890985 PCB Antibody,Santa Cruz Biotechnology,Cat# sc-271493 Clone H-2 RRID: AB_10649369 GLUT1 Recombinant Rabbit Monoclonal Antibody,Invitrogen,Cat# MA5–31960

(2) tRF-1:30-Gly-CCC-3 inhibits thyroid cancer via binding to PC and modulating metabolic reprogrammingLife science allianceMarch 1, 2024Fu B, Lou Y, Lu X, Wu Z, Ni J, Jin C, Wu P, Xu C.Western blotting. Antibodies against the following were used for Western blotting: mouse anti-PC antibody (sc-271493; Santa Cruz Biotechnology), mouse anti-ubiquitin antibody (3936; CST). Rabbit anti-GAPDH antibody (5174;

(3) Gonacin: A germ cell-derived hormone with glucogenic, orexigenic, and gonadal activitiesiScienceOctober 20, 2023Yixuan Hu, Shengyou Zhao, Zhiquan Liu, Tao Kang, Aaron J.W. Hsueh, Jianzhen LiRRID:AB_11182611 Rabbit Polyclonal Anti-Vasa,Abcam,Cat# ab209710 Mouse Monoclonal Anti-PCB,Santa Cruz Biotechnology,Cat# sc-271493; RRID:AB_10649369 HRP Conjugated Goat Anti-mouse IgG (H + L) Secondary Antibody,Cell Signaling Technology,Cat#

(4) Ferroptosis of CD163+ tissue-infiltrating macrophages and CD10+ PC+ epithelial cells in lupus nephritisFrontiers in ImmunologyJuly 31, 2023Qi Cheng, Lijun Mou, Wenjing Su, Xin Chen, Ting Zhang, Yifan Xie, Jing Xue, Pui Y. Lee, Huaxiang Wu, Yan Duanti-pyruvate carboxylase (anti-PC, 16588-1-AP, ProteinTech, Chicago, IL, USA), anti-pyruvate carboxylase (sc-271493, Santa Cruz Biotechnology, Dallas, TX, USA), anti-ATP6V0A4 (DF14858, Affinity Biosciences, Cincinnati,

(5) Short-term flaxseed oil, rich in omega 3, protects mice against metabolic damage caused by high-fat diet, but not inflammationThe Journal of nutritional biochemistryApril 1, 2023Nakandakari SCBR, Gaspar RC, Kuga GK, Ramos CO, Vieira RF, Rios TDS, Muñoz VR, Sant'ana MR, Simabuco FM, da Silva ASR, et al.

(6) Exercise training restores weight gain and attenuates hepatic inflammation in a rat model of non-celiac gluten sensitivityJournal of cellular biochemistryApril 1, 2023Pauli JR, Muñoz VR, Vieira RFL, Nakandakari SCBR, Macêdo APA, de Lima RD, Antunes GC, Simabuco FM, da Silva ASR, de Moura LP, et al.

(7) Genome-Wide CRISPR/Cas9 Library Screening Revealed Dietary Restriction of Glutamine in Combination with Inhibition of Pyruvate Metabolism as Effective Liver Cancer TreatmentAdvanced science (Weinheim, Baden-Wurttemberg, Germany)December 1, 2022Yang C, Lee D, Zhang MS, Tse AP, Wei L, Bao MH, Wong BP, Chan CY, Yuen VW, Chen Y, et al.anti‐PDHB (Abcam, Cambridge, UK; ab155996, 1:1000) and anti‐PC (Santa Cruz Biotechnology, Dallas, TX, USA; sc271493, 1:1000) antibodies, respectively. Cell Proliferation HCC cells were seeded onto 12‐well plates at

(8) Pyruvate carboxylase promotes malignant transformation of papillary thyroid carcinoma and reduces iodine uptakeCell death discoveryOctober 20, 2022Liu Y, Liu C, Pan Y, Zhou J, Ju H, Zhang Y.sulfoxide solution. The antibodies used in this study were: anti-PC (Santa Cruz Biotechnology, USA, sc-271493), anti-TSHR (Beyotime, AF1186), anti-NIS (Invitrogen, MA5-12308), anti-TPO (Abcam, UK, ab133322), anti-TG

(9) Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissueCell metabolismApril 5, 2022Rosina M, Ceci V, Turchi R, Chuan L, Borcherding N, Sciarretta F, Sánchez-Díaz M, Tortolici F, Karlinsey K, Chiurchiù V, et al.(ab23841, Abcam); anti-MDH2 (GTX105870, GeneTex); anti-HSP60 (sc-13966, Santa Cruz Biotechnology); anti-PC (sc-271493, Santa Cruz Biotechnology); anti-TOMM20 (sc-11415, Santa Cruz Biotechnology); anti-VDAC1 (sc-390996,

(10) Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic isletsCell reportsNovember 23, 2021Fu A, van Rooyen L, Evans L, Armstrong N, Avizonis D, Kin T, Bird GH, Reddy A, Chouchani ET, Liesa-Roig M, et al.antibody,Millipore Sigma,Cat# A2228; RRID: AB_476697 PCB monoclonal mouse antibody,Santa Cruz,Cat# sc-271493; RRID: AB_10649369 Bacterial and virus strains,, One Shot STABL3 cells,Sigma Aldrich,C737303 "Chemicals,

(11) Enzymatic activation of pyruvate kinase increases cytosolic oxaloacetate to inhibit the Warburg effectNature metabolismJuly 1, 2021Wiese EK, Hitosugi S, Loa ST, Sreedhar A, Andres-Beck LG, Kurmi K, Pang YP, Karnitz LM, Gonsalves WI, Hitosugi T.11242-1-AP), anti-GPT2 (Santa Cruz sc-398383), anti-PHGDH (Sigma HPA021241), and anti-PC (Santa Cruz sc-271493), horseradish peroxidase-conjugated secondary antibodies anti-mouse (Fisher PI31430) and anti-rabbit

(12) The Chinese patent medicine, Jin-tang-ning, ameliorates hyperglycemia through improving β cell function in pre-diabetic KKAy miceChinese journal of natural medicinesNovember 1, 2020Liu SN, Liu Q, Lei L, Sun SJ, Li CN, Huan Y, Hou SC, Shen ZF.

(13) Aging is associated with increased TRB3, ER stress, and hepatic glucose production in the liver of ratsExperimental gerontologyOctober 1, 2020Gaspar RC, Muñoz VR, Nakandakari SCBR, Vieira RFL, da Conceição LR, de Oliveira F, Crisol BM, da Silva ASR, Cintra DE, de Moura LP, et al.

(14) Low-protein/high-carbohydrate diet induces AMPK-dependent canonical and non-canonical thermogenesis in subcutaneous adipose tissueRedox biologySeptember 1, 2020Aquilano K, Sciarretta F, Turchi R, Li BH, Rosina M, Ceci V, Guidobaldi G, Arena S, D'Ambrosio C, Audano M, et al.Santa Cruz Biotechnology), anti-Ampk (sc-25792, Santa Cruz Biotechnology), anti-Hsl (#4107, Cell Signaling Technology), Pc (sc-271493, Santa Cruz Biotechnology), anti-Tom20 (sc-11415, Santa Cruz Biotechnolog), anti- Complex I ndufb8 (ms-105,

(15) Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinomaeLifeJuly 10, 2020Lau AN, Li Z, Danai LV, Westermark AM, Darnell AM, Ferreira R, Gocheva V, Sivanand S, Lien EC, Sapp KM, et al.Pierce BCA Protein Assay Kit (Pierce 23225). Western blots were performed using primary antibodies against PC (Santa Cruz sc-271493, 1:100 dilution), ME1 (Proteintech 16619–1-AP, 1:250 dilution), or β-actin (Cell Signaling Technologies

(16) Short-term Resistance Training Increases APPL1 Content in the Liver and the Insulin Sensitivity of Mice Fed a Long-term High-fat DietExperimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes AssociationJanuary 1, 2020Minuzzi LG, Kuga GK, Breda L, Gaspar RC, Muñoz VR, Pereira RM, Botezelli JD, da Silva ASR, Cintra DE, de Moura LP, et al.

(17) Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivoNature medicineSeptember 1, 2018Madiraju AK, Qiu Y, Perry RJ, Rahimi Y, Zhang XM, Zhang D, Camporez JG, Cline GW, Butrico GM, Kemp BE, et al.H-300 (Santa Cruz Biotechnology, Cat. No.: sc-32879), PCB H-2 (Santa Cruz Biotechnology, Cat. No.: sc-271493), Phospho-CREB Ser133 87G3 (Cell Signaling, Cat. No.: 9198), CREB 48H2 (Cell Signaling, Cat. No.: 9197),

(18) Physical exercise reduces pyruvate carboxylase (PCB) and contributes to hyperglycemia reduction in obese miceThe journal of physiological sciences : JPSJuly 1, 2018Muñoz VR, Gaspar RC, Crisol BM, Formigari GP, Sant'Ana MR, Botezelli JD, Gaspar RS, da Silva ASR, Cintra DE, de Moura LP, et al.

(19) Leptin Mediates a Glucose-Fatty Acid Cycle to Maintain Glucose Homeostasis in StarvationCellJanuary 11, 2018Perry RJ, Wang Y, Cline GW, Rabin-Court A, Song JD, Dufour S, Zhang XM, Petersen KF, Shulman GI.RESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies ApoB,Meridian Life Science,CAT#K23300R GAPDH,Cell Signaling,CAT#2118 Pyruvate carboxylase,Santa Cruz,CAT#sc-271493 Cytosolic PEPCK,Santa Cruz,CAT#sc-32879 Glucose-6-phosphatase,Santa Cruz,CAT#sc-27198 PGC1α,Santa Cruz

(20) Mechanisms by which a Very-Low-Calorie Diet Reverses Hyperglycemia in a Rat Model of Type 2 DiabetesCell metabolismJanuary 9, 2018Perry RJ, Peng L, Cline GW, Wang Y, Rabin-Court A, Song JD, Zhang D, Zhang XM, Nozaki Y, Dufour S, et al.

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PCB (H-2) Antibody

PCB (H-2) Antibody from Santa Cruz Biotechnology, Inc.

Santa Cruz Biotechnology, Inc.

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PCB (H-2) Antibody from Santa Cruz Biotechnology, Inc.

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