Fig 1: Immunohistochemical staining of USP14 and USP21 in tumor tissues obtained from patients with chemosensitive and chemoresistant metastatic bladder urothelial carcinoma. (A) Five chemoresistant and five chemosensitive clinical tumor samples were IHC-stained with USP14 and USP21 antibodies. The tissue sections were photographed at 200× magnification. (B) The IHC scores of USP14 and USP21 expression from chemoresistant and chemosensitive tumors. Data were analyzed using the unpaired two-tailed Student’s t-test and are presented as means ± standard deviation; * p < 0.05 represents a significant difference between the indicated groups.