SPARC Antibody MAB942 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemSPARC Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $599.00Supplier Page View Company Product Page
Catalog NumberMAB942
NCBI Gene AliasesON, OI17, BM-40, ONT
ApplicationsImmunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization,Intracellular Staining by Flow Cytometry,Immunocytochemistry,CyTOF-ready
Clone124413
Quantity500 ug (also 25 ug)
HostRat
Conjugate/TagUnconjugated
TargetSPARC
ReactivityMouse,Rat,Transgenic Mouse
IsotypeIgG2b
NCBI Full Gene Namesecreted protein acidic and cysteine rich, secreted acidic cysteine rich glycoprotein
ClonalityMonoclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ImmunogenMouse myeloma cell line NS0-derived recombinant mouse SPARC/Osteonectin, Ala18-Ile302, Accession # P07214
PurityProtein A or G purified from hybridoma culture supernatant
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects mouse SPARC/Osteonectin in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human SPARC is observed.

Sizes Available: 500 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Blood-triggered generation of platinum nanoparticle functions as an anti-cancer agentNature CommunicationsDecember 1, 2020Xin Zeng et al.including those against human albumin (MAB1455, 1:500), human SPARC (AF941, 1:500) and mouse SPARC (MAB942, 1:500) were purchased from R&D Systems (MN, USA). Anti-mouse albumin (ab207327, 1:500) was purchased

(2) Secreted protein acidic and rich in cysteine (SPARC) knockout mice have greater outflow facilityPloS oneJanuary 1, 2020Yu L, Zheng Y, Liu BJ, Kang MH, Millar JC, Rhee DJ.

(3) Implication of SPARC in the modulation of the extracellular matrix and mitochondrial function in muscle cellsPloS oneJanuary 1, 2018Melouane A, Carbonell A, Yoshioka M, Puymirat J, St-Amand J.inhibition/induction Monoclonal anti-SPARC (Mouse SPARC MAb "Clone 124413", Rat IgG2B, R&D systems, catalogue number: MAB942) (10–40 μg/ml) and rSPARC (R&D systems, catalogue number: 942-SP-050) (2–8 μg/ml) were directly added

(4) Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain InjuryThe Journal of neuroscience : the official journal of the Society for NeuroscienceFebruary 3, 2016Furman JL, Sompol P, Kraner SD, Pleiss MM, Putman EJ, Dunkerson J, Mohmmad Abdul H, Roberts KN, Scheff SW, Norris CM.#07-1492), GAPDH (Abcam, catalog #ab9484), hevin (R&D Systems, catalog #MAB2836), and SPARC (R&D Systems, catalog #MAB942). Membranes were then washed in PBS/0.1% Tween, incubated in LI-COR 800-conjugated anti-mouse and 680-conjugated

(5) SPARC Expression Did Not Predict Efficacy of nab-Paclitaxel plus Gemcitabine or Gemcitabine Alone for Metastatic Pancreatic Cancer in an Exploratory Analysis of the Phase III MPACT TrialClinical cancer research : an official journal of the American Association for Cancer ResearchNovember 1, 2015Hidalgo M, Plaza C, Musteanu M, Illei P, Brachmann CB, Heise C, Pierce D, Lopez-Casas PP, Menendez C, Tabernero J, et al.

(6) Clever-1/stabilin-1 controls cancer growth and metastasisClinical cancer research : an official journal of the American Association for Cancer ResearchDecember 15, 2014Karikoski M, Marttila-Ichihara F, Elima K, Rantakari P, Hollmén M, Kelkka T, Gerke H, Huovinen V, Irjala H, Holmdahl R, et al.

(7) Stromal disrupting effects of nab-paclitaxel in pancreatic cancerBritish journal of cancerAugust 20, 2013Alvarez R, Musteanu M, Garcia-Garcia E, Lopez-Casas PP, Megias D, Guerra C, Muñoz M, Quijano Y, Cubillo A, Rodriguez-Pascual J, et al.preclinical study, immunohistochemistry was performed using antibodies against mouse SPARC (R&D Systems, MAB942, Minneapolis, MN, USA) and cleaved caspase 3 (Cell Signaling Technology, 9661). Statistical analysis The

(8) SPARC mediates early extracellular matrix remodeling following myocardial infarctionAmerican journal of physiology. Heart and circulatory physiologyAugust 1, 2011McCurdy SM, Dai Q, Zhang J, Zamilpa R, Ramirez TA, Dayah T, Nguyen N, Jin YF, Bradshaw AD, Lindsey ML.

(9) Secreted protein acidic and rich in cysteine deficiency ameliorates renal inflammation and fibrosis in angiotensin hypertensionThe American journal of pathologyOctober 1, 2007Socha MJ, Manhiani M, Said N, Imig JD, Motamed K.

(10) Absence of SPARC in lens epithelial cells results in altered adhesion and extracellular matrix production in vitroJournal of cellular biochemistryFebruary 1, 2006Weaver MS, Sage EH, Yan Q.

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Mouse SPARC Antibody

SPARC Antibody

SPARC Antibody

SPARC Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (10)

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SPARC Antibody from R&D Systems, a Bio-Techne Brand

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