Human CD25/IL-2R alpha Antibody MAB1020 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman CD25/IL-2R alpha Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $599.00Supplier Page View Company Product Page
Catalog NumberMAB1020
NCBI Gene AliasesIMD41, CD25, TCGFR, IL2R, p55, IDDM10
ApplicationsFlow Cytometry,Western Blot,Blockade of Receptor-ligand Interaction,Neutralization,Immunocytochemistry,CyTOF-ready
HostMouse
Quantity500 ug (also 25 ug)
Conjugate/TagUnconjugated
ReactivityCanine,Human
IsotypeIgG2a
TargetCD25/IL-2R alpha
Clone24212
NCBI Full Gene Nameinterleukin 2 receptor subunit alpha
ClonalityMonoclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
PurityProtein A or G purified from hybridoma culture supernatant
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
ConcentrationLYOPH
ImmunogenS. frugiperda insect ovarian cell line Sf 21-derived recombinant human CD25/IL-2 R alpha, Glu22-Cys213, Accession # P01589

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Minimally invasive diagnosis of precancerous cervical lesions using single-cell peripheral immune atlasCell Reports MedicineJune 17, 2025Junfen Xu, Qinghua Ji, Quanming Kong, Lijuan Lv, Bo Zhu, Xiufeng Huang, Zhengyun Chen, Ping Xu, Xiao Li, Weiwei Yin, et al.(HIB19) - 148ND,BioLegend,Cat# 302202; RRID: AB_314232 Anti-Human CD25 (24212) - 149Sm,R&D Systems,Cat# MAB1020; RRID: AB_357376 Anti-Human CD274 (29E.2A3) - 150ND,BioLegend,Cat# 329710; RRID: AB_2275581 Anti-Human

(2) Ex vivo-expanded human CD19(+)TIM-1(+) regulatory B cells suppress immune responses in vivo and are dependent upon the TIM-1/STAT3 axisNature communicationsJune 3, 2022Shankar S, Stolp J, Juvet SC, Beckett J, Macklin PS, Issa F, Hester J, Wood KJ.

(3) E-cadherin phosphorylation occurs during its biosynthesis to promote its cell surface stability and adhesionMolecular biology of the cellAugust 15, 2014McEwen AE, Maher MT, Mo R, Gottardi CJ.

(4) A novel human CD4+ T-cell inducer subset with potent immunostimulatory propertiesEuropean journal of immunologyJanuary 1, 2010Ndhlovu LC, Leal FE, Eccles-James IG, Jha AR, Lanteri M, Norris PJ, Barbour JD, Wachter DJ, Andersson J, Taskén K, et al.

(5) Oxidized Low-Density Lipoproteins Activate CD4⁺T Cell Apoptosis in Patients with End-Stage Renal Disease through Fas EngagementJournal of the American Society of NephrologyJanuary 1, 2007Pascal Meier, François Spertini, Edouard Blanc, Michel Burnierdetermined by comparison with a standard curve. Blockade of IL-2R was performed using 2.5-␮g/ml blocking mAb (MAB1020 [␣], MAB224 [␤], MAB2841 [␥], R&D Systems) where appropriate. Supernatants of CD69⫹/CD4⫹ T cell cultures

(6) Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcriptionCellular immunologyMay 1, 2006Ebert EC, Mehta V.

(7) Functional characterization of EBV-encoded nuclear antigen 1-specific CD4+ helper and regulatory T cells elicited by in vitro peptide stimulationCancer researchFebruary 15, 2005Voo KS, Peng G, Guo Z, Fu T, Li Y, Frappier L, Wang RF.

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CD25/IL-2R alpha Antibody

CD25/IL-2R alpha Antibody

CD25/IL-2R alpha Antibody

Human CD25/IL-2R alpha Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (7)

Reviews

Human CD25/IL-2R alpha Antibody from R&D Systems, a Bio-Techne Brand

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