Mouse IgG1 Isotype Control MAB002 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMouse IgG1 Isotype Control
CompanyR&D Systems, a Bio-Techne Brand
Price $249.00Supplier Page View Company Product Page
Catalog NumberMAB002
TargetIgG1
Conjugate/TagUnconjugated
Quantity500 ug
ReactivityMouse
ApplicationsControl
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose
IsotypeIgG1 Kappa
Clone11711
HostMouse
ImmunogenKLH
ClonalityMonoclonal
ConcentrationLYOPH
PurityProtein A or G purified from hybridoma culture supernatant
Antibody TypeIsotype Controls
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Selected for use as mouse IgG1 isotype control. In direct ELISAs, does not cross-react with recombinant human (rh) 6Ckine, recombinant mouse (rm) 6Ckine, rhACT-II, rhBLC/BCA-1, rmBLC, rmC10, recombinant rat (rr) CINC-1, rrCINC-2 alpha, rrCINC-2ß, rrCINC-3, rhCKß8-1, recombinant viral (rv) CMV UL146, rmCRG-2, rhENA-78, rhEotaxin, rmEotaxin, rhEotaxin-2, rmEotaxin-2, rhEotaxin-3, rhFractalkine, rmFractalkine, rrFractalkine, rhGCP-2, rmGCP-2, rhGRO alpha, rhGROß, rhGRO gamma, rhHCC-1, rhI-309, rhI-Linck, rhIL-8, recombinant porcine IL-8, rhIP-10, rhI-TAC, rmJE, rmKC, rhLeukotactin-1, rhLymphotactin, rmLymphotactin, rmMARC, rhMCP-1, rhMCP-2, rhMCP-3, rhMCP-4, rmMCP-5, rvMCV type 2, rhMDC, rmMDC, rhMIG, rmMIG, rhMIP-1 alpha, rmMIP-1 alpha, rmMIP-1ß, rhMIP-1 delta, rmMIP-1 gamma, rmMIP-2, rhMIP-3 alpha, rmMIP-3 alpha, rrMIP-3 alpha, rhMIP-3ß, rmMIP-3ß, rvMIP-I, rvMIP-II, rvMIP-III, rhMPIF-1, rhNAP-2, rhPARC, rhRANTES, rmRANTES, rhSDF-1 alpha, rmSDF-1 alpha, rhSDF-1ß, rhTARC, rmTARC, rmTCA-3, rhTeck, or rmTeck.

Sizes Available: 500 ug

Add to Compare List

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Cell Type-Specific Extracellular Vesicles in Mouse Brain: Proteomic Signatures Highlight Astrocytic GlialCAM Network and GPCR EnrichmentGliaAugust 21, 2026Alba M. Lucart-Sanchez, Edward Sellés-Climent, Jorge Navarro-Calvo, Guillem Pont-Espinós, Jose A. Gomez-Sanchez, Raúl Estévez, Luis M. Valor, Rocío Pérez-GonzálezTo assess non‐specific binding, magnetic beads conjugated with an IgG control antibody (R&D Systems, MAB002) were incubated with brain EVs under identical conditions. Bulk EVs and unbound fractions corresponding

(2) The human cytomegalovirus chemokine binding protein UL22A is necessary for efficient reactivation from latency in CD34 + hematopoietic progenitor cells and humanized miceJournal of VirologyAugust 18, 2026Rebekah L. Turner, Nicole L. Diggins, Luke Slind, Jennifer Mitchell, Andrew H. Pham, Christopher J. Parkins, Wilma Perez, Samuel Medica, Michael Denton, Takeshi F. Andoh, et al.with Human/Primate CCL5/RANTES antibody (MAB678, R&D Systems) and Mouse IgG1 isotype control antibody (MAB002, R&D Systems). HCMV UL22A was amplified by PCR with an upstream primer (5′-GAATTCGCCACCATGGCTCGGAGGCTATGGATC-3′)

(3) A fatty acid amide activates myeloid cells and improves neurovascular outcomes in retinal degenerationNature NeuroscienceJune 19, 2026Guoqin Wei, Shreyosree Chatterjee, Qinglin Yang, Sanahan Vijayakumar, Daisuke Ogasawara, Sarah Giles, Katie Biscocho, Peter Westenskow, Junhua Wang, Ruhan Fan, et al.FGF-2 (05-117, Sigma-Aldrich, 1 μg μl−1), Mouse IgG1 Isotype Control (control for FGF, R&D systems, MAB002, 1 μg μl−1), VEGF164 (R&D systems, AF-493-NA, 200 ng μl−1) and Goat IgG Control (control for VEGF164,

(4) A feedback loop sustaining neutrophil extracellular trap formation involves S100 proteins, histones, TLR2 and RAGE, and is restrained by albuminFront ImmunolJune 1, 2026Vanessa de Carvalho Oliveira, Matthew Mazur, Patrick P. McDonald#Y107112). An anti-rabbit antibody (AB-105-C), goat serum (AB-108-C), and a mouse IgG1 isotype control (MAB002) were from R&D Systems; mouse IgG2 (5013051) and IgM (14-4752-81) isotype controls were from eBioscience.

(5) Loss of IGFBP-6 promotes monocyte-driven atherogenesis in periodontal diseaseScientific ReportsMay 12, 2026Dáire Shanahan, Georgios Kremastiotis, Kerry Wadey, Claudine Hodgson, Joon Seong, Nicola West, Angela H. Nobbs, Jason Johnson, Sarah George(R&D Systems; 292-G2), neutralising IGF-2 antibody (R&D Systems; MAB292) or IgG control (R&D Systems; MAB002) were applied to assess whether IGFBP-6 effects were mediated via IGF-2 signalling. To assess the effect

(6) Mutant KRAS promotes NF-κB driven CCL20 chemokine expression in pancreatic ductal adenocarcinomabioRxivApril 18, 2026Donovan Drouillard, Marissa Davies, Donna McAllister, Michael B. DwinellIgG Alexa fluor 647 (ThermoFisher #A48289) at a concentration of 1:500. A mouse IgG1 (R&D Systems #MAB002) was used as an isotype control. Sections were counterstained with a mountant containing Hoechst 33342

(7) Targeting ST18-mediated pathomechanism in pemphigus vulgaris through voltage-dependent anion channel inhibitionSkin Health and DiseaseMarch 31, 2026Sari Assaf, Ofer Sarig, Rawaa Ishtewy, Yazeed Zoabi, Yarden Feller, Kiril Malovitski, Janan Mohamad, Shir Bergson, Carmel Bilu, Varda Shoshan-Barmatz, et al.to 1.2 mmol L–1) (D219-3; Biozol, Eching, Germany), a monoclonal mouse IgG1 antibody (3.75 μg mL–1) (MAB002; R&D Systems, Minneapolis, MN, USA), VBIT-12 [20 μmol L–1 (31445; Cayman Chemical, Ann Arbor MI, USA)]

(8) Interleukin-9 Regulates NF-kB-Mediated Activation of Astrocytes in Multiple Sclerosis BrainNeurology Neuroimmunology & NeuroinflammationMarch 1, 2026Miriam Cinotti, Susanna Amadio, Daniele Tidei, Gloria Donninelli, Costanza Stacchiotti, Veronica De Paolis, Emanuela Colombo, Anthea De Angelis, Francesca Ruffini, Gianvito Martino, et al.receptor,1:100,"MAB290, R&D Systems, Minneapolis, United States",IHC/IF Isotype IgG,"Mouse (mAB, IgG)",—,1:100,"MAB002, R&D Systems, Minneapolis, United States",IF IL-9R,Rabbit (pAB),Interleukin-9 receptor,1:500,"ABCAM,

(9) Vitamin D receptor expression in germinal centre type diffuse large B-cell lymphoma cells is associated with vitamin D insensitivityEndocrine OncologyFebruary 26, 2026Elizabeth J Soilleux, Amanda Anderson, Emma Roberts, Linden Lyne, Kah Keng Wong, Hayley Spearman, Stefano Casola, Alison H Banham, Duncan M Gascoyne1:20), CD38 (Vector Laboratories, UK; VP-C348 at 1:50) or isotype control (mIgG1 R&D Systems, USA; MAB002 at 1:50) were applied overnight at 4°C or room temperature for 30 min, and the EnVision system (Dako,

(10) Targeting ST18-mediated pathomechanism in pemphigus vulgaris through voltage-dependent anion channel inhibitionSkin Health and DiseaseJanuary 19, 2026Sari Assaf, Ofer Sarig, Rawaa Ishtewy, Yazeed Zoabi, Yarden Feller, Kiril Malovitski, Janan Mohamad, Shir Bergson, Carmel Bilu, Varda Shoshan-Barmatz, et al.to 1.2 mmol L–1) (D219-3; Biozol, Eching, Germany), a monoclonal mouse IgG1 antibody (3.75 μg mL–1) (MAB002; R&D Systems, Minneapolis, MN, USA), VBIT-12 [20 μmol L–1 (31445; Cayman Chemical, Ann Arbor MI, USA)]

(11) Interleukin-9 Regulates NF-kB-Mediated Activation of Astrocytes in Multiple Sclerosis BrainNeurol Neuroimmunol NeuroinflammJanuary 13, 2026Miriam Cinotti, Susanna Amadio, Daniele Tidei, Gloria Donninelli, Costanza Stacchiotti, Veronica De Paolis, Emanuela Colombo, Anthea De Angelis, Francesca Ruffini, Gianvito Martino, et al.receptor,1:100,"MAB290, R&D Systems, Minneapolis, United States",IHC/IF Isotype IgG,"Mouse (mAB, IgG)",—,1:100,"MAB002, R&D Systems, Minneapolis, United States",IF IL-9R,Rabbit (pAB),Interleukin-9 receptor,1:500,"ABCAM,

(12) Inhibition of cell surface GRP78 and activated α2M interaction attenuates kidney fibrosisJCI insightDecember 22, 2025Trink J, Nmecha IK, Pilely K, Li R, Yang Z, Kwiecien S, MacDonald M, Gao B, Mamai MA, Lu C, et al.neutralizing antibody (10 μg, R&D Systems, MAB1835); or preadsorbed IgG control (10 μg, R&D Systems, MAB002). Protein extraction and Western blotting. Cells were lysed with cell lysis buffer containing protease

(13) Investigation of neutrophil infiltration in the acute canine atopic dermatitis modelFront AllergyDecember 16, 2025Chie Tamamoto-Mochizuki, Santosh K. Mishraperipheral blood was used as a positive control, and a mouse IgG1 isotype control antibody (1 μg/mL; MAB002, R&D Systems, Minneapolis, MN) served as a negative control to verify the sensitivity and specificity

(14) CXCL5 neutralization mitigates cancer cachexia by disrupting CAF-cancer cell crosstalkJournal of biomedical scienceDecember 15, 2025Kim HJ, Kim SW, Kim JH, Lee SH, Joo KH, Lee SY, Lee H, Min JJ, Cho SH, Jung DW, et al.(12D10),Monoclonal,Merck,MABE-343,1:2000 Alpha-tubulin,Polyclonal,Invitrogen,PA5-29444,1:1000 Vimentin,Monoclonal,CST,5741S,1:100 Cytokeratin,Polyclonal,Abcam,Ab9377,1:100 CXCR2,Polyclonal,Invitrogen,PA5-100951,1:1000 Laminin,Polyclonal,Abcam,Ab11575,1:1000 Mouse IgG1 Isotype control,Monoclonal,R&D systems,MAB002,120 μg/kg Human CXCL5/ENA-78 Antibody,Monoclonal,R&D systems,MAB254-500,120 μg/kg Primary antibodies

(15) The human cytomegalovirus chemokine binding protein UL22A is necessary for efficient reactivation from latency in CD34 (+) hematopoietic progenitor cells and humanized micebioRxiv : the preprint server for biologyDecember 4, 2025Turner RL, Diggins NL, Slind L, Mitchell J, Pham AH, Parkins CJ, Perez W, Medica S, Denton M, Andoh TF, et al.

(16) SOAT1 in ovarian cancer cells regulates immune response mediated by CD8(+) T cellsJournal of ovarian researchNovember 19, 2025He J, Siu MKY, Long R, Hung L, Zhang R, Yung MMH, Lu H, Ngan HYS, Chan KKL.R&D Systems) and anti-IL-8 (2.0 µg/mL, MAB208, R&D Systems) antibodies, or corresponding isotype controls (MAB002, R&D Systems) were added to the TCM during the incubation with CD8 + T cells. CD8+ T cells were then

(17) IL-5 signaling in asthmatic derived fibroblasts exacerbates airway remodeling through ECM dysregulation and apoptosis resistanceRespiratory ResearchNovember 4, 2025Rola Abujabal, Tasneem M. Alanta, Reem Sami Alhamidi, Alaa Muayad Altaie, Lina Sahnoon, Bushra Mdkhana, Bassam Mahboub, Yves Laumonnier, Rifat Hamoudi, Khuloud Bajbouj, et al.Cell Signalling Technology), Rabbit mAb IgG XP® Isotype Control (Cat: 3900, CST), Mouse IgG isotype control (Cat: MAB002, R&D systems) at a 1:100 dilution. After washing with PBS, the cells were incubated with Alexa Fluor®

(18) Monocyte/macrophage-derived interleukin-15 mediates the pro-inflammatory phenotype of CD226(+) B cells in type 1 diabetesEBioMedicineOctober 1, 2025Li J, Liang X, Zhao M, Luo W, Huang J, Xiao Y, Huang J, Zhao B, Zhou Z.R&D Systems, Cat#MAB666, RRID:AB_2072624) or mouse IgG1 isotype control (10 μg/mL; R&D Systems, Cat#MAB002, RRID:AB_357344) to inhibit CD226 on B cells in vitro. To assess the responsiveness of human B cells

(19) The S1P/S1P1 Signaling Axis Plays Regulatory Functions in the Crosstalk Between Brain-Metastasizing Melanoma Cells and MicrogliaCancers (Basel)September 29, 2025Orit Adir, Orit Sagi-Assif, Shlomit Ben-Menachem, Isaac P. Witz, Sivan Izraely-blocking antibody (1 μg/mL, MAB227, R&D Systems, Minneapolis, MA, USA) or IgG1 isotype control antibody (1 μg/mL, MAB002, R&D Systems), then treated with MCM and anti-IL-6Rα/IgG1 isotype control for an additional 3 h. 2.5.

(20) KDM6B promotes ferroptosis in rheumatoid arthritis fibroblast-like synoviocytes via the miR-128-3p/SLC7A11 axis through H3K27me3 modificationJournal of Orthopaedic Surgery and ResearchSeptember 29, 2025Bin Wang, Song Gao, Zongwei Liu, Yan Cong, Chuansheng WuDCABH-4439, Creative Diagnostics), H3K27me3 (1:500, ab6002, Abcam), or a negative control (mouse IgG, 1:100, MAB002, NOVUS, Littleton, CO, USA). Following de-crosslinking with NaCl and proteinase K, DNA was extracted,

Be the First to Write a Review!

Mouse IgG1 Isotype Control

Mouse IgG1 Isotype Control

Mouse IgG1 Isotype Control

Mouse IgG1 Isotype Control from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (521)

Reviews

Mouse IgG1 Isotype Control from R&D Systems, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map