PDX-1/IPF1 Antibody MAB2419 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemPDX-1/IPF1 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberMAB2419
NCBI Gene AliasesIPF1, PDX-1, IUF1, IDX-1, MODY4, GSF, PAGEN1, STF-1
ReactivityHuman,Mouse
HostMouse
Quantity100 ug (also 25 ug)
IsotypeIgG2b
Clone267712
NCBI Full Gene Namepancreatic and duodenal homeobox 1
ApplicationsWB, FCM, ICC, IHC, IHC-p
ConcentrationLYOPH
PurityProtein A or G purified from hybridoma culture supernatant
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
ImmunogenE. coli-derived recombinant human PDX-1, Ala91-Arg283, Accession # P52945
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ClonalityMonoclonal
TargetPDX-1/IPF1
Conjugate/TagUnconjugated

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human and mouse PDX-1 in Western blots.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Clinical outcomes of gastroenteropancreatic neuroendocrine neoplasms in Taiwan: A multicenter registry study—TCOG T1214 studyCancerAugust 20, 2025Hui‐Jen Tsai, Ming‐Huang Chen, Hsiu‐Po Wang, Chin‐Fu Hsiao, Yen‐Yang Chen, Jen‐Shi Chen, Mei‐Due Yang, Chin‐Yuan Tzen, Yan‐Shen Shan, Li‐Yaun Bai, et al.Dickinson Biosciences, Franklin Lakes, NJ, USA), monoclonal PDX‐1 antibody (amino acids 91 to 283) (MAB2419, clone 267712; R&D Systems, Minneapolis, MN, USA), monoclonal SSTR2 antibody (1:50; clone UMB1, Abcam,

(2) Patient derived tumoroids of high grade neuroendocrine neoplasms for more personalized therapiesNPJ Precis OncolMarch 1, 2024Simon L. April-Monn, Philipp Kirchner, Katharina Detjen, Konstantin Bräutigam, Mafalda A. Trippel, Tobias Grob, Cyril Statzer, Renaud S. Maire, Attila Kollàr, Aziz Chouchane, et al.(1:100, Cell Signaling, 82630 T D8G8H), ARX (1:1500, R&D Systems, AF7068), PDX1 (1:100, R&D Systems, MAB2419); in a Tris-EDTA buffer for 30 min at 100 °C for synaptophysin (1:100, Novocastra, 27G12), CgA (1:400,

(3) DNA methylation reveals distinct cells of origin for pancreatic neuroendocrine carcinomas and pancreatic neuroendocrine tumorsGenome medicineMarch 1, 2022Simon T, Riemer P, Jarosch A, Detjen K, Di Domenico A, Bormann F, Menne A, Khouja S, Monjé N, Childs LH, et al.2.5μm FFPE sections for ARX (1:1500, R&D Systems, sheep, AF7068), PDX1 (1:100, R&D Systems, mouse, MAB2419), and SOX9 (1:100, Cell Signaling, rabbit, mAb #82630) immunostainings. Antigen retrieval was performed

(4) Intrinsically disordered substrates dictate SPOP subnuclear localization and ubiquitination activityThe Journal of biological chemistryJanuary 1, 2021Usher ET, Sabri N, Rohac R, Boal AK, Mittag T, Showalter SA.antibodies used were mouse anti-Pdx1 used at 1:500 for pulldown or 1:2000 for inputs (clone 26771, MAB2419, R&D Systems), mouse anti-myc (1:250, clone 9E10, Santa Cruz Biotechnology), and rabbit anti-GAPDH (1:8000,

(5) Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progressionCommunications biologyDecember 7, 2020Di Domenico A, Pipinikas CP, Maire RS, Bräutigam K, Simillion C, Dettmer MS, Vassella E, Thirlwell C, Perren A, Marinoni I.whole blocks were used for ARX (1:1500, R&D Systems, sheep, AF7068), PDX1 (1:100, R&D Systems, mouse, MAB2419), insulin (1:12000, Sigma–Aldrich, mouse, I-2018) and glucagon (1:20000, Sigma–Aldrich, mouse, G-2654)

(6) Coxsackievirus B Type 4 Infection in β Cells Downregulates the Chaperone Prefoldin URI to Induce a MODY4-like Diabetes via Pdx1 SilencingCell reports. MedicineOctober 20, 2020Bernard H, Teijeiro A, Chaves-Pérez A, Perna C, Satish B, Novials A, Wang JP, Djouder N.monoclonal anti-HA Tag (16B12),BioLegend,MMS-101R; RRID:AB_291262 Mouse monoclonal anti-PDX1,R&D Systems,MAB2419; RRID:AB_2268098 Mouse monoclonal anti-URI,This paper,N/A Mouse monoclonal anti-Vinculin,Sigma,V9131;

(7) YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK-STAT3 SignalingGastroenterologySeptember 1, 2016Gruber R, Panayiotou R, Nye E, Spencer-Dene B, Stamp G, Behrens A.Cell Signaling; #9157); LIFR (Santa Cruz Biotechnology; sc-659); PDX1 (R&D Systems, Minneapolis, MN; MAB2419); SOX9 (Millipore, Billerica, MA; AB5535); p-Erk1/2 (Thr202/Tyr204; Cell Signaling; #9106); Erk1/2 (Cell Signaling

(8) The combined effect of PDX1, epidermal growth factor and poly-L-ornithine on human amnion epithelial cells' differentiationBMC developmental biologyApril 12, 2016Balaji S, Zhou Y, Ganguly A, Opara EC, Soker S.immunofluorescence staining was a monoclonal anti-mouse Pdx1 antibody (R&D systems, USA; catalog # MAB2419). Secondary antibody was horse anti-mouse IgG-Texas red conjugated antibody (H + L; Vector Labs, USA;

(9) A programmable synthetic lineage-control network that differentiates human IPSCs into glucose-sensitive insulin-secreting beta-like cellsNature communicationsApril 11, 2016Saxena P, Heng BC, Bai P, Folcher M, Zulewski H, Fussenegger M.(F25A1B3, lot no. GR95038; dilution 1:100; Developmental Studies Hybridoma Bank), mouse anti-Pdx1 IgG (MAB2419, lot no. C267712; dilution 1:2,000; R&D Systems), rabbit anti-MafA IgG (sc-66958, lot no. C1609; dilution

(10) Redifferentiation of adult human β cells expanded in vitro by inhibition of the WNT pathwayPloS oneJanuary 1, 2014Lenz A, Toren-Haritan G, Efrat S.

(11) Pdx1 expression in pancreatic precursor lesions and neoplasmsApplied immunohistochemistry & molecular morphology : AIMMOctober 1, 2011Park JY, Hong SM, Klimstra DS, Goggins MG, Maitra A, Hruban RH.placenta. Immunohistochemistry Pdx1 mouse monoclonal antibody that recognizes the C-terminus of Pdx1 (amino acids 91 to 283) (MAB2419, clone 267712; R&D Systems, Minneapolis, MN) was used for immunohistochemistry. In brief, formalin-fixed paraffin embedded

(12) Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structureMolecular and cellular biologyApril 1, 2009Evans-Molina C, Robbins RD, Kono T, Tersey SA, Vestermark GL, Nunemaker CS, Garmey JC, Deering TG, Keller SR, Maier B, et al.

(13) Betacellulin and nicotinamide sustain PDX1 expression and induce pancreatic beta-cell differentiation in human embryonic stem cellsBiochemical and biophysical research communicationsFebruary 1, 2008Cho YM, Lim JM, Yoo DH, Kim JH, Chung SS, Park SG, Kim TH, Oh SK, Choi YM, Moon SY, et al.

(14) Generation of insulin-producing cells from PDX-1 gene-modified human mesenchymal stem cellsJournal of cellular physiologyApril 1, 2007Li Y, Zhang R, Qiao H, Zhang H, Wang Y, Yuan H, Liu Q, Liu D, Chen L, Pei X.

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PDX-1/IPF1 Antibody

PDX-1/IPF1 Antibody

PDX-1/IPF1 Antibody

PDX-1/IPF1 Antibody

PDX-1/IPF1 Antibody

PDX-1/IPF1 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (14)

Reviews

PDX-1/IPF1 Antibody from R&D Systems, a Bio-Techne Brand

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