Human/Mouse Pin1 Antibody MAB2294 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman/Mouse Pin1 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $489.00Supplier Page View Company Product Page
Catalog NumberMAB2294
ApplicationsImmunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry
Quantity100 ug (also 25 ug)
Conjugate/TagUnconjugated
ReactivityHuman,Mouse
TargetPin1
IsotypeIgG2b
Clone257417
HostMouse
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ImmunogenE. coli-derived recombinant human Pin1, Ala2-Glu163, Accession # Q13526
ConcentrationLYOPH
PurityProtein A or G purified from hybridoma culture supernatant
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
ClonalityMonoclonal
NCBI Full Gene Namepeptidylprolyl cis/trans isomerase, NIMA-interacting 1
NCBI Gene AliasesUBL5, DOD

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Identification of potential new T cell activation molecules: a Bioinformatic ApproachScientific reportsSeptember 27, 2024Morales-Martínez M, Andón-García D, Patiño-Santiago KA, Parga-Ortega JM, Hernández-Hernández A, Aquino-Jarquin G, Patino-Lopez G.(1:10000, Abcam, Ab233396), α-CD53 (1:1000, Novus biologicals, NB500393), α-PIN1 (1:1000, RyD Systems, MAB2294), α-HBZ (1:1000, R&D Systems, MAB7708), α-MDM4 (1:1000, Novus Biologicals, NB100556), all the primary

(2) Correlative Multi-Modal Microscopy: A Novel Pipeline for Optimizing Fluorescence Microscopy Resolutions in Biological ApplicationsCellsJanuary 17, 2023Pelicci S, Furia L, Pelicci PG, Faretta M.rabbit polyclonal anti-53BP1 (ab36823, Abcam, Cambridge, UK), and mouse monoclonal IgG2b DynLL1/Pin1 (MAB2294, R&D systems, Minneapolis, MN, USA). Cells were washed 3 times in PBS and incubated for 45 min at room

(3) The fission yeast Pin1 peptidyl-prolyl isomerase promotes dissociation of Sty1 MAPK from RNA polymerase II and recruits Ssu72 phosphatase to facilitate oxidative stress induced transcriptionNucleic acids researchJanuary 25, 2021Wang YT, Hsiao WY, Wang SW.M2 antibody was from Sigma-Aldrich (Saint Louis, MO, USA). Anti-Pin1 antibody was from R&D Systems (MAB2294, MN, USA). Antibody against α-tubulin (Sigma-Aldrich, Saint Louis, MO) was used as a control. For immunoprecipitation

(4) Isomerization of BRCA1-BARD1 promotes replication fork protectionNatureJuly 1, 2019Daza-Martin M, Starowicz K, Jamshad M, Tye S, Ronson GE, MacKay HL, Chauhan AS, Walker AK, Stone HR, Beesley JFJ, et al.BD Biosciences 347580 8151735 Fibres 1:500 γH2AX Rabbit Abcam Ab2893 GR3242597-1 IF 1:2000 AB_303388 PALB2 Rabbit Bethyl A301.246A WB 1:2000 AB_890607 AB_2163944 PIN1 Mouse R&D Systems MAB2294 WB 1:1000 RAD51 (H-92) Rabbit Santa Cruz SC8349 E0616 WB/IF 1:1000 AB_2253533 RAD51 (Ab-1) Tubulin Rabbit Calbiochem PC130 3135376 PLA 1:100 AB_2238184 Mouse Santa Cruz

(5) TLR-7 Stress Signaling in Differentiating and Mature Eosinophils Is Mediated by the Prolyl Isomerase Pin1Journal of immunology (Baltimore, Md. : 1950)December 15, 2018Shen ZJ, Hu J, Kashi V, Bochkov YA, Gern JE, Malter JS.

(6) Cytoplasmic Pin1 expression is increased in human cutaneous melanoma and predicts poor prognosisScientific reportsNovember 15, 2018Chen X, Liu X, Deng B, Martinka M, Zhou Y, Lan X, Cheng Y.immunohistochemically stained as described previously35. The monoclonal mouse anti-Pin1 antibody (Cat # MAB2294) (1:50 dilution; R&D Systems, MN, USA) was diluted 1:100 and used. Negative controls were performed

(7) Pin1 mediates Aβ₄₂-induced dendritic spine lossScience signalingMarch 20, 2018Stallings NR, O'Neal MA, Hu J, Kavalali ET, Bezprozvanny I, Malter JS.B Amyloid 17–24 (4G8, Covance) were used to detect oligomers. XL-Bead Preparation Pin1 antibody (MAB2294, R&D Systems) or normal mouse IgG (SC-2025, Santa Cruz) were immobilized on Protein G Sepharose® Fast

(8) Targeted inhibition of metastatic melanoma through interference with Pin1-FOXM1 signalingOncogeneApril 28, 2016Kruiswijk F, Hasenfuss SC, Sivapatham R, Baar MP, Putavet D, Naipal KA, van den Broek NJ, Kruit W, van der Spek PJ, van Gent DC, et al.in vitro (MPP2; C-20 and H-92), control immunoglobulin G, R&D systems (Minneapolis, MN, USA): Pin1 (MAB2294), Sigma-Aldrich: Pin1 (WH0005300M1, St Louis, MO, USA), FLAG-M2 (F1804), Tubulin (T5168), Abcam: CENPF

(9) The peptidyl-prolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson diseaseThe Journal of biological chemistryJuly 26, 2013Ghosh A, Saminathan H, Kanthasamy A, Anantharam V, Jin H, Sondarva G, Harischandra DS, Qian Z, Rana A, Kanthasamy AG.

(10) A distinct role for Pin1 in the induction and maintenance of pluripotencyThe Journal of biological chemistryApril 1, 2011Nishi M, Akutsu H, Masui S, Kondo A, Nagashima Y, Kimura H, Perrem K, Shigeri Y, Toyoda M, Okayama A, et al.

(11) The peptidyl-isomerase Pin1 regulates p27kip1 expression through inhibition of Forkhead box O tumor suppressorsCancer researchSeptember 15, 2008Brenkman AB, de Keizer PL, van den Broek NJ, van der Groep P, van Diest PJ, van der Horst A, Smits AM, Burgering BM.

(12) Protein Never in Mitosis Gene A Interacting-1 (PIN1) regulates degradation of inducible nitric oxide synthase in endothelial cellsAmerican journal of physiology. Cell physiologySeptember 1, 2008Liu T, Huang Y, Likhotvorik RI, Keshvara L, Hoyt DG.

(13) Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosisThe Journal of clinical investigationFebruary 1, 2008Shen ZJ, Esnault S, Rosenthal LA, Szakaly RJ, Sorkness RL, Westmark PR, Sandor M, Malter JS.

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Pin1 Antibody

Pin1 Antibody

Pin1 Antibody

Pin1 Antibody

Pin1 Antibody

Human/Mouse Pin1 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (13)

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Human/Mouse Pin1 Antibody from R&D Systems, a Bio-Techne Brand

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