Mer Biotinylated Antibody BAF591 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMer Biotinylated Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $629.00Supplier Page View Company Product Page
Catalog NumberBAF591
NCBI Gene Aliasesc-mer, c-Eyk, Eyk, Mer, nmf12, Nyk, MER, Tyro12, RP38
IsotypeIgG
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
TargetMer
Quantity50 ug
ReactivityMouse,Transgenic Mouse
HostGoat
Conjugate/TagBiotin
NCBI Full Gene NameMER proto-oncogene, tyrosine kinase, MER proto-oncogene tyrosine kinase
ApplicationsWB, ELISA-det, FCM, ICC, IHC, IP
ClonalityPolyclonal
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
PurityAntigen Affinity-purified
ConcentrationLYOPH
ImmunogenS. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse Mer, Glu23-Phe498, Accession # Q60805

Specifications/Features

Available conjugates: Available conjugates: Biotin

Specificity: Detects mouse Mer in Western blots. In Western blots, no cross-reactivity with recombinant mouse (rm) Axl and rmDtk is observed.

Sizes Available: 50 ug

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) RELMα establishes a permissive environment for influenza virus infection through direct effects on lung epithelial cellsJournal of VirologyAugust 18, 2026Roksana Shirazi, Sang Yong Kim, Aaron Cruz, James P. Stumpff, Stefanie N. Sveiven, Sumaya Alaama, Jennell Jennett, Brandon H. Le, Meera G. Nair, Juliet Morrison(Gibco) to remove red blood cells. Pleural cells were incubated with biotinylated anti-MERTK antibody (BAF591, R&D System), and the lung single-cell suspension was incubated with anti-CD326 (EpCAM) microbeads (Miltenyi Biotec

(2) Early-age efferocytosis directs macrophage arachidonic acid metabolism for tissue regenerationImmunityFebruary 11, 2025Connor Lantz, Amanda Becker, Matthew DeBerge, Mallory Filipp, Kristofor Glinton, Aparnaa Ananthakrishnan, Jessica Urbanczyk, Madeline Cetlin, Afnan Alzamroon, Ahmed Abdel-Latif, et al.423102 BV421 anti-mouse CD64,BioLegend,Cat#: 101257 MerTK biotinylated mouse antibody,R&D Systems,Cat#: BAF591 BV711 Streptavidin,BioLegend,Cat#: 405241 PE anti-mouse CCR2,R&D Systems,Cat#: FAB5538P APC-Cy7 anti-mouse

(3) Inflammatory crosstalk impairs phagocytic receptors and aggravates atherosclerosis in clonal hematopoiesis in miceThe Journal of clinical investigationNovember 12, 2024Liu W, Hardaway BD, Kim E, Pauli J, Wettich JL, Yalcinkaya M, Hsu CC, Xiao T, Reilly MP, Tabas I, et al.following: anti–Mac-2 (Cedarlane, CL8942AP, 1:10,000); GFP (Abcam, ab13970, 1:500); MERTK (R&D Systems, BAF591, 1:200); anti–IL-1β (Abcam, ab9722 1:200); anti-TREM2 (Denali, 4D9 DC1847 or Proteintech 27599-1-AP,

(4) Fibroblastic reticular cells provide a supportive niche for lymph node–resident macrophagesEuropean Journal of ImmunologySeptember 1, 2023Joshua D'Rozario, Konstantin Knoblich, Mechthild Lütge, Christian Pérez Shibayama, Hung‐Wei Cheng, Yannick O. Alexandre, David Roberts, Joana Campos, Emma E. Dutton, Muath Suliman, et al.BV711",30‐F11,Biolegend ,CD45,PerCPCy5.5,I3/2.3,Biolegend ,CD31,Biotin,MEC13.3,Biolegend ,CD31,FITC,390,BD ,CD31,"BV605, PECy7",390,Biolegend ,MERTK,Biotin,BAF591,R&D Systems ,MHCII,"BV510, Pacific blue",M5/114.15.2,Biolegend ,CD169,FITC,3D6.112,Biolegend ,GR‐1,PE,RB6‐8C5,BD ,F480,"PE,

(5) Efferocytes release extracellular vesicles to resolve inflammation and tissue injury via prosaposin-GPR37 signalingCell reportsJuly 25, 2023Bhattacharya P, Dhawan UK, Hussain MT, Singh P, Bhagat KK, Singhal A, Austin-Williams S, Sengupta S, Subramanian M.

(6) The Akt-mTORC1 pathway mediates Axl receptor tyrosine kinase-induced mesangial cell proliferationJournal of leukocyte biologyMarch 1, 2022Zhen Y, McGaha TL, Finkelman FD, Shao WH.promote proliferation. Materials and methods Antibodies Goat antibodies to Axl (BAF854) and Mer (BAF591) were purchased from R&D Systems (Minneapolis, MN). All other antibodies were purchased from Cell Signaling

(7) Pomegranate Peel Extract Decreases Plaque Necrosis and Advanced Atherosclerosis Progression in Apoe (-/-) MiceFrontiers in pharmacologyJanuary 1, 2022Manickam V, Dhawan UK, Singh D, Gupta M, Subramanian M.1:50 dilution, Invitrogen), anti-smooth muscle actin (A2547, 1:100 dilution, Sigma), anti-mouse Mertk (BAF591, 1:100 dilution, R&D Systems), or anti-8-OHdG (BS-1278R, 1:100 dilution, Thermofisher Scientific) for

(8) STAT5 is activated in macrophages by breast cancer cell-derived factors and regulates macrophage function in the tumor microenvironmentBreast cancer research : BCRNovember 7, 2021Jesser EA, Brady NJ, Huggins DN, Witschen PM, O'Connor CH, Schwertfeger KL.30-F11), Ly6G (BioLegend, clone 1A8), CD64 (BioLegend, clone X54-5/7.1), MerTK (R&D Systems, polyclonal #BAF591, biotinylated). CountBright Absolute Counting Beads (Life Technologies) were used for cell number calculations.

(9) Human and Mouse Transcriptome Profiling Identifies Cross-Species Homology in Pulmonary and Lymph Node Mononuclear PhagocytesCell reportsNovember 3, 2020Leach SM, Gibbings SL, Tewari AD, Atif SM, Vestal B, Danhorn T, Janssen WJ, Wager TD, Jakubzick CV.558539 "Goat anti mouse MerTK biotinylated, polyclonal",R&D Systems,RRID:AB_2098563; R&D Systems Cat# BAF591 "Rat anti mouse CD11b PerCp-Cy5.5, clone M1/70",BioLegend,RRID:AB_893232; BioLegend Cat# 101228 "Rat

(10) Reticular Fibroblasts Expressing the Transcription Factor WT1 Define a Stromal Niche that Maintains and Replenishes Splenic Red Pulp MacrophagesImmunityJuly 14, 2020Bellomo A, Mondor I, Spinelli L, Lagueyrie M, Stewart BJ, Brouilly N, Malissen B, Clatworthy MR, Bajénoff M.(ED31) Euromedex Cat#GTX43404; RRID: AB_11162718 Anti-mouse MERTK (Polyclonal Goat IgG) R&D Systems Cat#BAF591; RRID: AB_2098563 Anti-mouse MHCII (M5/114.15.2) Biolegend Cat#107628; RRID: AB_2069377 Anti-mouse

(11) Phagocytosis of Wnt inhibitor SFRP4 by late wound macrophages drives chronic Wnt activity for fibrotic skin healingScience advancesMarch 1, 2020Gay D, Ghinatti G, Guerrero-Juarez CF, Ferrer RA, Ferri F, Lim CH, Murakami S, Gault N, Barroca V, Rombeau I, et al.eBioscience), anti-CD64 allophycocyanin (APC; X54-5/7.1, BioLegend), anti-MERTK biotin (R&D Systems BAF591), anti-CD301b Alexa Fluor 647 (LOM-8.7, BioLegend), anti-CD206 APC (C068C2, BioLegend), anti-CD45 (clone

(12) The Kidney Contains Ontogenetically Distinct Dendritic Cell and Macrophage Subtypes throughout Development That Differ in Their Inflammatory PropertiesJournal of the American Society of Nephrology : JASNFebruary 1, 2020Salei N, Rambichler S, Salvermoser J, Papaioannou NE, Schuchert R, Pakalniškytė D, Li N, Marschner JA, Lichtnekert J, Stremmel C, et al.V3GYWCH) were purchased from Thermo Fisher Scientiﬁc. Anti–Mer-Biotin (clone unknown, catalog number BAF591) was purchased from R&D systems. Transwell Chemotaxis Assay A total of 0.53105 leukocytes from kidneys

(13) Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseasesThe Journal of experimental medicineSeptember 2, 2019Fujino N, Brand OJ, Morgan DJ, Fujimori T, Grabiec AM, Jagger CP, Maciewicz RA, Yamada M, Itakura K, Sugiura H, et al.anti-P63 (ab735 [4A4], 1/100; Abcam); goat anti-Axl (AF854, 4 µg/ml; R&D Systems); goat anti-Mertk (BAF591, 4 µg/ml; R&D Systems); goat anti-Tyro3 (AF759, 4 µg/ml; R&D Systems); goat anti-Gas6 (BAF986, 4 µg/ml;

(14) Lymphatic Endothelial Cells Are Essential Components of the Subcapsular Sinus Macrophage NicheImmunityJune 18, 2019Mondor I, Baratin M, Lagueyrie M, Saro L, Henri S, Gentek R, Suerinck D, Kastenmuller W, Jiang JX, Bajénoff M.CF405M,Biotium,20373 Anti-goat CF568,Biotium,20106 Anti-mouse MERTK (Polyclonal Goat IgG),R&D Systems,BAF591 Bacterial and Virus Strains,Bacterial and Virus Strains,Bacterial and Virus Strains Vesicular stomatitis Indiana virus

(15) MERTK tyrosine kinase receptor together with TIM4 phosphatidylserine receptor mediates distinct signal transduction pathways for efferocytosis and cell proliferationThe Journal of biological chemistryMay 3, 2019Nishi C, Yanagihashi Y, Segawa K, Nagata S.

(16) Interferon induced protein 35 exacerbates H5N1 influenza disease through the expression of IL-12p40 homodimerPLoS pathogensApril 1, 2018Gounder AP, Yokoyama CC, Jarjour NN, Bricker TL, Edelson BT, Boon ACM.inflammation and influenza disease 7.1), CD11b (Biolegend, clone M1/70), and MerTK (R&D Systems, catalog BAF591) which was followed by streptavidin Qdot-605 secondary staining (Invitrogen, catalog Q10101MP). Stained

(17) Conventional DCs from Male and Female Lupus-Prone B6.NZM Sle1/Sle2/Sle3 Mice Express an IFN Signature and Have a Higher Immunometabolism That Are Enhanced by EstrogenJournal of immunology researchJanuary 1, 2018Lee MH, Chakhtoura M, Sriram U, Caricchio R, Gallucci S.

(18) A Discrete Subset of Monocyte-Derived Cells among Typical Conventional Type 2 Dendritic Cells Can Efficiently Cross-PresentCell reportsOctober 31, 2017Sheng J, Chen Q, Soncin I, Ng SL, Karjalainen K, Ruedl C.

(19) Mouse macrophages show different requirements for phosphatidylserine receptor Tim4 in efferocytosisProceedings of the National Academy of Sciences of the United States of AmericaAugust 15, 2017Yanagihashi Y, Segawa K, Maeda R, Nabeshima YI, Nagata S.

(20) Pivotal role for skin transendothelial radio-resistant anti-inflammatory macrophages in tissue repaireLifeJune 15, 2016Barreiro O, Cibrian D, Clemente C, Alvarez D, Moreno V, Valiente Í, Bernad A, Vestweber D, Arroyo AG, Martín P, et al.

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Mer Biotinylated Antibody

Mer Biotinylated Antibody

Mer Biotinylated Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (29)

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Mer Biotinylated Antibody from R&D Systems, a Bio-Techne Brand

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