IL-21 Antibody AF594 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-21 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF594
ApplicationsELISA Development,ELISpot Development,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Neutralization,ELISA Capture (Matched Antibody Pair),Immunocytochemistry,ELISA Capture
Conjugate/TagUnconjugated
ReactivityBovine,Human,Mouse,Transgenic Mouse
HostGoat
Quantity100 ug (also 25 ug)
TargetIL-21
IsotypeIgG
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
NCBI Full Gene Nameinterleukin 21
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant mouse IL-21 (R&D Systems, Catalog # 594-ML), Pro25-Ser146, Accession # Q9ES17
NCBI Gene AliasesZa11, IL-21, CVID11
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects mouse IL-21 in ELISAs and Western blots. In sandwich ELISAs, less than 0.5% cross-reactivity with recombinant mouse (rm) IL-2, rmIL-4, rmIL-15, and recombinant human IL-21 is observed.

Sizes Available: 100 ug (also 25 ug)

Add to Compare List

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Seeing clearly with CLARI-O: a window into cellular architecture, interactions, and morphology of organoid modelsFrontiers in NeuroscienceJuly 28, 2026Samra Beyene, Martin Thunemann, Natalie Baker Campbell, Elizabeth K. Kharitonova, Shira Klorfeld-Auslender, Farzad Mortazavi, Ella Zeldichantibodies Anti-GABA (Sigma, cat. A2052, RRID: AB_477652)Anti-GFAP (Abcam, cat. ab4674, RRID: AB_304558)Anti-GFAP-AF594 (Novus Biologicals, cat. NBP1-05197AF594, RRID: AB_3198395)Anti-Iba1 (Aves Labs, cat. IBA1, RRID: AB_2910556)Anti-MAP2

(2) Nur77 agonism invigorates Natural Killer cell immunity against hepatocellular carcinomaNature CommunicationsJune 30, 2026Shi Yong Neo, Yu Mei, Joni Chong, Kang Yi Lee, Jyue Yuan Lim, Menaka P. Rajapakse, Timothy Wai Ho Shuen, Junzhe Zhao, Le Tong, Tasneem Kajiji, et al.included CD45 AF532 (2B11 + PD7/26, Novus Biologicals (Novus), Littleton, CO, USA, 19.25 µg/mL), CK8/18 AF594 (K8.8 + DC10, Novus, 10 µg/mL) Nur77 AF647 (Novus, 34 µg/ml) and counter-stained with Syto 13 (50 µM)

(3) Human cerebral organoids with microglia and vasculature model glioma stem cell interactions and radiotherapy responseCell Reports MethodsJune 15, 2026Jérémy Raguin, Noa Legrand, Thierry Kortulewski, Oriane Bergiers, Christine Granotier-Beckers, Laure Chatrousse, Alexandra Benchoua, Laurent R. Gauthier, François D. Boussin, Marc-André MouthonAB_2783290 SSEA3-AF488,R and D Systems,Clone identity: MC-631 Cat#FAB1434G RRID: AB_3646484 TRA-1-81-AF594,R and D Systems,Clone identity: TRA-1-81 Cat#IC8495T RRID: AB_3662726 AIF-1/Iba1,Novus,Clone identity:

(4) Long-acting IL-7 induces distinct transcriptomic features in peripheral T cells of patients with solid tumorsJCI InsightJune 8, 2026Ho Cheol Jang, Jeong Yeon Kim, Sojeong Kim, Heewon Kim, Mi Sun Byun, Myung Ah Lee, Jong Hee Chang, Do-Hyun Nam, Tae Won Kim, Sin-Soo Jeun, et al.anti–p-STAT5-APC (clone 47) from BD Biosciences, anti–c-Myc-APC (clone 9E10) from R&D Systems, and anti–PIM-1-AF594 (clone 12H8) from Santa Cruz Biotechnology. ADA test. ADAs were determined by enzyme-linked immunosorbent assay

(5) Plasma Regulates Homeostatic Pulmonary Endothelial Signaling to Mitigate Vascular Leak Following Polytrauma and Hemorrhagic ShockShockMay 8, 2026Taylor E. Wallen, Krystal L. Rivera-Figueroa, James D. Odum, Giacynta Vollmer, Lei Zheng, Melad N. Dababneh, Delores A. Stacks, Camilla Margaroli, Robert P. Richter, Jillian R. Richterepithelial cells, smooth muscle, and nuclei, respectively: AF647-conjugated anti-CD31/PECAM-1 (Bio-Techne; 1:50), AF594-conjugated anti-EpCAM (Abcam; 1:82), AF532–conjugated anti-myosin heavy chain 11 (Abcam; 1:20), and

(6) Spatial predictors of response to chemo-immunotherapy in microsatellite stable metastatic colorectal cancerNature CommunicationsApril 25, 2026Joan Choo, Joseph J. Zhao, Mai Chan Lau, Alessandra Raimondi, Willa Wen-You Yim, Sruthi Ranganathan, Kexin Zhu, Crystal Tze Ying Tan, Hui Xian Chin, Chong Boon Teo, et al.a cocktail of morphology markers including CD45 AF532 (2B11 + PD7/26, Novus, at 10.2 μg/ml), PanCK AF594 (AE-1/AE-3, Novus at 3.25 μg/ml), αSMA AF647 (1A4/asm-1, Novus at 8 μg/ml) and counter stained with

(7) WITHDRAWN: Spatial Analysis of Placentae During Congenital Cytomegalovirus Infection Reveals Distinct Cellular Profiles in Immune Cells and TrophoblastsbioRxivApril 12, 2026Elise Sintim-Aboagye, Huy Quang Quach, Will Sherman, Sheila Farnan, Kamila Otrubova, Namisha Verma, Dawn Littlefield, Sohan Punia, Erica Johnson, Mark Blackstad, et al.(oligo)-conjugated antibodies (Supplemental Table 2) at 4 °C. Fluorescent antibodies included anti-CD45-AF594 (2B11+PD7/26, 5 μg/mL, Novus)), anti-PanCK-AF532 (AE1+AE3, 2 μg/mL, Novus), and anti-SYTO-FITC (1:200,

(8) Temporal regulation of human reactive astrocytes reveals their capacity for antigen presentationNeuronMarch 30, 2026Emily Jane Hill, Caitlin Sojka, Maureen McGuirk Sampson, Nardos Kebede, Hsiao-Lin V. Wang, Shainoor Showrin, Alexia Tyler King, Anson David Sing, Jianjun Chang, Emory Brain Organoid Emory Brain Organoid Hub, et al.labeling kit- blue fluorescence, Abcam, ab187963, 1:1000 IFN-γ-APC, Invitrogen, 17-7319-41, 1:200 HepaCAM-AF594, R&D Systems, MAB4108, 1:200, conjugated to AlexaFluor594 ELISA Fetal human astrocytes (GW20) were

(9) Clinical and molecular features of primary gliosarcoma with digital spatial whole‐transcriptome analysis of glial and mesenchymal componentsBrain PathologyMarch 18, 2026Matthew D. Wood, Gabriel Zangirolani, Jinho Lee, Melanie H. Hakar, Tanaya Neff, Kevin Y. Zhang, Christopher L. Corlessh. After stringent washes, tissues were stained with GFAP (AF647, Novus Cat# NBP1‐05197), vimentin (AF594, Santa Cruz, Cat# sc‐373,717), and Syto‐13 (Thermo Fisher Scientific Cat# S7575) at room temperature

(10) NF-κB–driven lymphangiogenesis affects kidney function via a VEGFR-3–mediated pathwayJCI InsightMarch 9, 2026Arin L. Melkonian, Amie M. Traylor, Anna A. Zmijewska, Kyle H. Moore, Gelare Ghajar-Rahimi, Stephanie Esman, Yanlin Jiang, Hani Jang, Babak J. Mehrara, Timmy C. Lee, et al.at 37°C. Tissues were subsequently washed and incubated with secondary antibodies (1:300 dilution; AF594 and AF647 for LYVE-1 [Novabus, nb-6008] and VEGFR-3 [R&D Systems, AF743], respectively) for 96 hours

(11) MyD88 signaling in myeloid cells induces gastrointestinal tract injury and systemic inflammation after West Nile virus infectionCell ReportsJanuary 27, 2026Shih-Ching Lin, Fang R. Zhao, Matthias Mack, Gabriel Mbalaviele, Michael S. DiamondRRID:AB_10982846 Rabbit anti-CCR2 polyclonal antibody,Novus Biologicals,Cat#NBP1-48338SS; RRID: AB_10011102 AF594-conjugated donkey anti-rat antibody,ThermoFisher,Cat#A-21209; RRID:AB_2535795 AF647-conjugated donkey

(12) A membranous nephropathy variant mimicking minimal change diseaseThe Journal of Pathology: Clinical ResearchJanuary 1, 2026Chuqi Pan, Silin Xiang, Mengya Jiang, Yuan Li, Biao Huang, Tian Ye, Yuanyuan Du, Xuanli Tang, Yuan Yuan(R&D Systems; AF904), and mouse anti‐human THRA1 (R&D Systems; MAB2916), followed by incubation with secondary AF594‐conjugated anti‐rabbit, anti‐goat, and anti‐mouse IgG (1:200, Invitrogen). After the first antibody

(13) Cadherin-1-mediated communication at the leader-follower boundary controls mouse breast tumor organoid collective migrationCell ReportsDecember 23, 2025Vasilios A. Morikis, Diego Barra Avila, Alessandra DiMauro, Yanyang Cao, Priscilla Y. Hwang, Amit Pathak, Gregory D. LongmoreNCD-2)",Invitrogen,Cat# 13-2100; RRID: AB_2533007 "P-cadherin (Cdh3, PF-03732010)","Pfizer, Zhang et al.42",NA "AF594 P-Cadherin (Cdh3, Clone: 106020)",R&D Systems,Cat# FAB761T; RRID: AB_3652558 APC/Cy7 Thy-1.1 (Clone:

(14) Lithium attenuates HIV-1 latency reversal in an autophagy independent wayiScienceDecember 19, 2025Ana Luiza Abdalla, Gabriel Guajardo-Contreras, Bao-An Chau, Meijuan Niu, Thomas Murooka, Andrew J. Moulandwith D-PBS and stained. Acquisition was done same day. Antibodies concentration: 1:50 mouse anti-LC3B AF594 (Novus Biologicals); 1:100 rabbit anti-LC3B (Abcam) 1:100 anti-ATG5 AF647 (R&D systems), 1:100 anti-Beclin1

(15) Host-specific bacterial modulation of airway gene expression and alternative splicingmSphereNovember 25, 2025Horvath M, Kang HG, Wu T-C, Aiken E, Castaneda DC, Akkurt S, Marches F, Anczuków O, Palucka K, Oh J.sections were stained with directly conjugated anti-MUC5AC AF700 (Clone45M1, Novus) and anti-cytokeratin 5 AF594 (rabbit polyclonal, Novus) for 1 hour and washed. Finally, sections were counterstained with 4',6-diamidino-2-phenylindole

(16) Epithelial and stromal remodeling in murine Crohn's disease-like ileitisbioRxiv : the preprint server for biologyNovember 9, 2025Letai KC, Islam BN, Menghini P, De Salvo C, Khandekar NS, Armstrong BW, Tomar A, Curry K, Pizarro TT, Tesar PJ, et al.(anti-rabbit AF647, Proteintech 55013–1-AP), IGF1 (anti-goat AF488, Biotechne AF791), COL1A1 (anti-rabbit AF594, Boster PA2140–2), ACTA2 (anti-mouse AF647, Abcam ab7817). Slides were washed and incubated with Donkey

(17) Artemin sensitises mouse (Mus musculus) and naked mole-rat (Heterocephalus glaber) sensory neurons in vitroJ Comp Physiol A Neuroethol Sens Neural Behav PhysiolNovember 1, 2025Lanhui Qiu, Ewan St. John Smithantibody diluent. Slides were washed three times with PBS-Tween and incubated with anti-guinea pig AF594 (Invitrogen, A11076) and anti-goat Alexa-568 (Invitrogen, A11057) secondary antibodies for 2 h at room

(18) MRI of ASCT2-mediated amino acid uptake in xenograft tumor modelsResearch SquareOctober 27, 2025Behnaz Ghaemi, Balaji Krishnamachary, Natalie Dillman, Kirsten N. Bains Bains Williams, Yuki Hodo, Yuguo Li, Marie-France Penet Penet Vidaver, Martin G. Pomper, Caitlin M. Tressler, Zaver M. Bhujwalla, et al.NB600–1475, 1:200) and with rabbit anti-ASCT2 (1:100). Donkey anti-rat AF488 and donkey anti-rabbit AF594 were used as secondary antibodies. Western blot. Pa20c-naïve and Pa20c-ASCT2 cells were lysed for

(19) NNMT inhibition in cancer-associated fibroblasts restores antitumour immunityNatureSeptember 25, 2025Janna Heide, Agnes J. Bilecz, Samarjit Patnaik, Maria Francesca Allega, Leonhard Donle, Kaiting Yang, Ethan Teich, Yan Li, Qiaoshan Lin, Ke Kong, et al.included: pan-cytokeratin (pan-CK; Novus Biologicals, NBP2-33200AF532, AF532, 1:40), CD45 (NBP2-34528AF594, AF594, 1:20), CD163 (Abcam, ab218294, AF647, 1:100), and SYTO 13 nuclear stain (NanoString, 121300303, FITC,

(20) Imidazole propionate is a driver and therapeutic target in atherosclerosisNatureSeptember 4, 2025Annalaura Mastrangelo, Iñaki Robles-Vera, Diego Mañanes, Miguel Galán, Marcos Femenía-Muiña, Ana Redondo-Urzainqui, Rafael Barrero-Rodríguez, Eleftheria Papaioannou, Joaquín Amores-Iniesta, Ana Devesa, et al.CD86-PECy7 (Biolegend), FOXP3-FITC (Biolegend), CD4-BV570 (Biolegend), CD31-PE (Biolegend) and VCAM-AF594 (Biotechne). Cells were washed and resuspended in FACS buffer for data acquisition using a LSRFortessa

Be the First to Write a Review!

IL-21 Antibody

IL-21 Antibody

IL-21 Antibody

IL-21 Antibody

IL-21 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (137)

Reviews

IL-21 Antibody from R&D Systems, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map