CCL17/TARC Antibody AF529 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemCCL17/TARC Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $519.00Supplier Page View Company Product Page
Catalog NumberAF529
NCBI Gene AliasesScya17l, SCYA17, Scya17, TARC, ABCD-2, Tarc, Abcd-2, A-152E5.3
ApplicationsConfocal Microscopy,Flow Cytometry,Immunohistochemistry,Western Blot,In vivo assay,Neutralization,Immunocytochemistry
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
TargetCCL17/TARC
HostGoat
ReactivityHuman,Mouse,Transgenic Mouse
Quantity100 ug (also 25 ug)
Conjugate/TagUnconjugated
IsotypeIgG
NCBI Full Gene Namechemokine (C-C motif) ligand 17, C-C motif chemokine ligand 17
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant mouse CCL17/TARC, Ala24-Pro93, Accession # Q9WUZ6
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects mouse CCL17/TARC in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross-reactivity with recombinant human TARC is observed. Neutralizes the biological activity of recombinant mouse TARC, and will also neutralize the biological activity of recombinant human TARC using a 20 fold greater Ig concentration.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) PGE(2)-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironmentCell reportsJune 7, 2022Thumkeo D, Punyawatthananukool S, Prasongtanakij S, Matsuura R, Arima K, Nie H, Yamamoto R, Aoyama N, Hamaguchi H, Sugahara S, et al.

(2) Single-cell RNA sequencing uncovers the individual alteration of intestinal mucosal immunocytes in Dusp6 knockout miceiScienceFebruary 18, 2022Chang CS, Yu WH, Su CC, Ruan JW, Lin CM, Huang CT, Tsai YT, Lin IJ, Lai CY, Chuang TH, et al.immuno-stained with anti-CD209 antibody (1:100; LS-C782089, LifeSpan BioSciences) and anti-CCL17 antibody (1:50; AF529, R&D systems) followed by Alexa Fluor 488 Goat anti-Rabbit IgG (H + L) Highly Cross-Adsorbed Secondary

(3) Prolactin enhances T regulatory cell promotion of breast cancer through the long form prolactin receptorTranslational oncologyNovember 1, 2021Chen KE, Ghosh M, Rivera L, Lin S, Kumar A, Swaminathan S, Lorenson MY, Walker AM.chamber in the presence or absence of 1 μg/mL mouse anti-CCL17 or anti-CCL22 antibody (R & D systems, AF529, AF479, respectively). Cells that migrated into the lower chamber in 1 h were collected and analyzed

(4) Targeting fibroblast CD248 attenuates CCL17-expressing macrophages and tissue fibrosisScientific reportsOctober 8, 2020Pai CH, Lin SR, Liu CH, Pan SY, Hsu H, Chen YT, Yen CT, Yu IS, Wu HL, Lin SL, et al.as a control. In neutralization experiments, UUO mice were injected with 4 μg of anti-mouse CCL17 (AF529; R&D Systems, Minneapolis, MN) or isotype control immunoglobulin G (IgG) (AB-108-C; R&D Systems) intraperitoneally

(5) Cross-talk between iNKT cells and CD8 T cells in the spleen requires the IL-4/CCL17 axis for the generation of short-lived effector cellsProceedings of the National Academy of Sciences of the United States of AmericaDecember 17, 2019Valente M, Dölen Y, van Dinther E, Vimeux L, Fallet M, Feuillet V, Figdor CG.

(6) Eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challengeNature communicationsSeptember 24, 2018Yi S, Zhai J, Niu R, Zhu G, Wang M, Liu J, Huang H, Wang Y, Jing X, Kang L, et al.130-048-101) were purchased from Miltenyi Biotec. Purified neutralizing antibodies to CCL17/TARC (Cat: AF529) and CCL22/MDC (Cat: AF439), were obtained from R&D Systems. Purified blocking antibody against CD4

(7) IL-4/CCL22/CCR4 axis controls regulatory T-cell migration that suppresses inflammatory bone loss in murine experimental periodontitisJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral ResearchMarch 1, 2015Araujo-Pires AC, Vieira AE, Francisconi CF, Biguetti CC, Glowacki A, Yoshizawa S, Campanelli AP, Trombone AP, Sfeir CS, Little SR, et al.

(8) Defective immunoregulation in RSV vaccine-augmented viral lung disease restored by selective chemoattraction of regulatory T cellsProceedings of the National Academy of Sciences of the United States of AmericaFebruary 19, 2013Loebbermann J, Durant L, Thornton H, Johansson C, Openshaw PJ.

(9) Identification of chemoattractive factors involved in the migration of bone marrow-derived mesenchymal stem cells to brain lesions caused by prionsJournal of virologyNovember 1, 2011Song CH, Honmou O, Furuoka H, Horiuchi M.

(10) Comprehensive assessment of chemokine expression profiles by flow cytometryThe Journal of clinical investigationMarch 1, 2010Eberlein J, Nguyen TT, Victorino F, Golden-Mason L, Rosen HR, Homann D.

(11) Allergic pulmonary inflammation in mice is dependent on eosinophil-induced recruitment of effector T cellsThe Journal of experimental medicineMarch 17, 2008Jacobsen EA, Ochkur SI, Pero RS, Taranova AG, Protheroe CA, Colbert DC, Lee NA, Lee JJ.

(12) CCL17 transgenic mice show an enhanced Th2-type response to both allergic and non-allergic stimuliEuropean journal of immunologyAugust 1, 2006Tsunemi Y, Saeki H, Nakamura K, Nagakubo D, Nakayama T, Yoshie O, Kagami S, Shimazu K, Kadono T, Sugaya M, et al.

(13) Immunosuppressive effects of CCL17 on pulmonary antifungal responses during pulmonary invasive aspergillosisInfection and immunityNovember 1, 2005Carpenter KJ, Hogaboam CM.

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CCL17/TARC Antibody

CCL17/TARC Antibody

CCL17/TARC Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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CCL17/TARC Antibody from R&D Systems, a Bio-Techne Brand

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