CD40/TNFRSF5 Antibody AF632 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemCD40/TNFRSF5 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $529.00Supplier Page View Company Product Page
Catalog NumberAF632
NCBI Gene AliasesTNFRSF5, Bp50, p50, CDW40
ApplicationsBioassay,Immunohistochemistry,Western Blot,Simple Western,Agonist Activity,Neutralization
TargetCD40/TNFRSF5
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
HostGoat
Quantity100 ug (also 25 ug)
IsotypeIgG
Conjugate/TagUnconjugated
ReactivityHuman,Mouse
NCBI Full Gene NameCD40 molecule
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant human CD40, Glu21-Arg193, Accession # P25942
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human CD40 in direct ELISAs and Western blots.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) A PDGFRB- and CD40-targeting bispecific AffiMab induces stroma-targeted immune cell activationmAbsJanuary 1, 2023Mega A, Mebrahtu A, Aniander G, Ryer E, Sköld A, Sandegren A, Backström Rydin E, Rockberg J, Östman A, Frejd FY.test. Surface plasmon resonance Affinity determinations of the antibody and AffiMab toward human CD40 (ref. AF632, R&D systems) and human PDGFRB (ref. 10676-PR−100, R&D systems) were made using a BIAcore 8K instrument

(2) Bispecific antibody target pair discovery by high-throughput phenotypic screening using in vitro combinatorial Fab librariesmAbsJanuary 1, 2021Bhatta P, Whale KD, Sawtell AK, Thompson CL, Rapecki SE, Cook DA, Twomey BM, Mennecozzi M, Starkie LE, Barry EMC, et al.(Jackson ImmunoResearch, Cat. No. 109–006-129) and 1 µg/mL anti-CD40 antibody (Biotechne, Cat. No. AF632) and plates were incubated at 37°C, 5% CO2 for 5 d. Proliferation and activation of B cells was measured

(3) Children with oligoarticular juvenile idiopathic arthritis have skewed synovial monocyte polarization pattern with functional impairment-a distinct inflammatory pattern for oligoarticular juvenile arthritisArthritis research & therapyAugust 12, 2020Schmidt T, Berthold E, Arve-Butler S, Gullstrand B, Mossberg A, Kahn F, Bengtsson AA, Månsson B, Kahn R.

(4) Expression, purification and biological characterization of the extracellular domain of CD40 from Pichia pastorisBMC biotechnologyJanuary 25, 2016Zhan Y, Wei Y, Chen P, Zhang H, Liu D, Zhang J, Liu R, Chen R, Zhang J, Mo W, et al.using Super Signal West Pico Chemiluminescent Substrate (Pierce). The primary antibody against CD40-N (AF632) was purchased from R&D Systems. The anti-Flag antibody was purchased from Sigma (F3165). Mouse monoclonal

(5) CD19 and CD32b differentially regulate human B cell responsivenessJournal of immunology (Baltimore, Md. : 1950)February 15, 2014Karnell JL, Dimasi N, Karnell FG 3rd, Fleming R, Kuta E, Wilson M, Wu H, Gao C, Herbst R, Ettinger R.

(6) CD40.FasL inhibits human T cells: evidence for an auto-inhibitory loop-back mechanismInternational immunologyApril 1, 2007Dranitzki-Elhalel M, Huang JH, Sasson M, Rachmilewitz J, Parnas M, Tykocinski ML.

(7) Disruption of CD40/CD40 ligand interaction with cleavage of CD40 on human gingival fibroblasts by human leukocyte elastase resulting in down-regulation of chemokine productionJournal of leukocyte biologySeptember 1, 2002Nemoto E, Tada H, Shimauchi H.

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CD40/TNFRSF5 Antibody

CD40/TNFRSF5 Antibody

CD40/TNFRSF5 Antibody

CD40/TNFRSF5 Antibody

CD40/TNFRSF5 Antibody

CD40/TNFRSF5 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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CD40/TNFRSF5 Antibody from R&D Systems, a Bio-Techne Brand

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