FGF acidic/FGF1 Antibody AF232 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemFGF acidic/FGF1 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF232
NCBI Gene AliasesHBGF1, FGF-1, FGF-alpha, GLIO703, ECGFA, ECGFB, ECGF, FGFA, HBGF-1, AFGF, ECGF-beta
ApplicationsImmunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Simple Western,Neutralization,Immunocytochemistry
Conjugate/TagUnconjugated
IsotypeIgG
Quantity100 ug (also 25 ug)
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHuman,Mouse,Rat
TargetFGF acidic/FGF1
HostGoat
NCBI Full Gene Namefibroblast growth factor 1
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant human FGF acidic/FGF1, Phe16-Asp155, Accession # P05230
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human FGF acidic/FGF1 in direct ELISAs and Western blots. In direct ELISAs, approximately 100% cross-reactivity with recombinant mouse FGF acidic/FGF1 is observed. Neutralizes the biological activity of rhFGF acidic/FGF1. It will also neutralize the biological activity of rhß-ECGF and bovine FGF acidic/FGF1, although 2-3 times the amount of IgG is required to neutralize bovine FGF acidic/FGF1 biological activity.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Tumor-derived Immunoglobulin-like transcript 4 facilitates angiogenesis of colorectal cancerAmerican journal of cancer researchJanuary 1, 2023Liu J, Zhang F, He J, Wang S, Wang L, Li J, Shi W, Han Y, Gao A, Sun Y.

(2) Fibroblast growth factor signalling influences homologous recombination-mediated DNA damage repair to promote drug resistance in ovarian cancerBritish journal of cancerOctober 1, 2022Nicholson HA, Sawers L, Clarke RG, Hiom KJ, Ferguson MJ, Smith G.NaCl, 1% Tween-20), and membranes incubated overnight at 4 °C with either goat polyclonal anti-FGF1 (AF232, R&D Systems, Oxfordshire, UK, diluted 1:1000), rabbit polyclonal anti-GFP (G1544, Sigma Aldrich, diluted

(3) Nuclear Localization Sequence of FGF1 Is Not Required for Its Intracellular Anti-Apoptotic Activity in Differentiated CellsCellsFebruary 2, 2022Lampart A, Sluzalska KD, Czyrek A, Szerszen A, Otlewski J, Wiedlocha A, Zakrzewska M.(3139), and rabbit anti-FGFR2 (11835) from Cell Signaling Technology (Danveres, MA, USA); goat anti-FGF1 (AF232) from R&D Systems (Minneapolis, MN, USA); mouse anti-lamin A (ab8980)and rabbit anti-FGFR3 (ab10559)

(4) Acidic fibroblast growth factor underlies microenvironmental regulation of MYC in pancreatic cancerThe Journal of experimental medicineAugust 3, 2020Bhattacharyya S, Oon C, Kothari A, Horton W, Link J, Sears RC, Sherman MH.anti-FGFR1 (phospho Y653) antibody (EPR843 [N]; Abcam, ab173305); anti-FGF1 antibody (R&D Systems, AF232); FGFR1 mAb (VBS-7; Invitrogen, 13–3100); NPM1 mAb (FC-61991; Invitrogen, 32–5200); pan-KRT (C11) mouse

(5) Pituitary Adenylate Cyclase-Activating Peptide (PACAP), a Novel Secretagogue, Regulates Secreted Morphogens in Newborn Rat RetinaInvestigative ophthalmology & visual scienceJanuary 1, 2017Lakk M, Denes V, Kovacs K, Hideg O, Szabo BF, Gabriel R.

(6) FGF1 C-terminal domain and phosphorylation regulate intracrine FGF1 signaling for its neurotrophic and anti-apoptotic activitiesCell death & diseaseFebruary 4, 2016Delmas E, Jah N, Pirou C, Bouleau S, Le Floch N, Vayssière JL, Mignotte B, Renaud F.overexpressing FGF1 or treating with recombinant FGF1. We also tested the effect of an anti-FGF1 antibody (AF232, R&D Systems) added at a concentration of 12.5 and 25 μg/ml in the culture media to measure its neutralizing

(7) WNT7A/β-catenin signaling induces FGF1 and influences sensitivity to niclosamide in ovarian cancerOncogeneJune 1, 2015King ML, Lindberg ME, Stodden GR, Okuda H, Ebers SD, Johnson A, Montag A, Lengyel E, MacLean Ii JA, Hayashi K.

(8) Beneficial effects of coculturing synovial derived mesenchymal stem cells with meniscus fibrochondrocytes are mediated by fibroblast growth factor 1: increased proliferation and collagen synthesisStem cells internationalJanuary 1, 2015Song X, Xie Y, Liu Y, Shao M, Wang W.

(9) Reduction of brain metastases in plasminogen activator inhibitor-1-deficient mice with transgenic ocular tumorsCarcinogenesisNovember 1, 2008Maillard CM, Bouquet C, Petitjean MM, Mestdagt M, Frau E, Jost M, Masset AM, Opolon PH, Beermann F, Abitbol MM, et al.

(10) Molecular profiling of cervical cancer progressionBritish journal of cancerJanuary 29, 2007Hagemann T, Bozanovic T, Hooper S, Ljubic A, Slettenaar VI, Wilson JL, Singh N, Gayther SA, Shepherd JH, Van Trappen PO.

(11) FGFR2b signaling regulates ex vivo submandibular gland epithelial cell proliferation and branching morphogenesisDevelopment (Cambridge, England)March 1, 2005Steinberg Z, Myers C, Heim VM, Lathrop CA, Rebustini IT, Stewart JS, Larsen M, Hoffman MP.

(12) Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigmsCancer cellJanuary 1, 0001"Hu H, Piotrowska Z, Hare PJ, Chen H, Mulvey HE, Mayfield A, Noeen S, Kattermann K, Greenberg M, Williams A, et al."anti-Mouse secondary antibody,ThermoScientific,Cat# A-31571 anti-FGF1 neutralizing antibody,R&D System,Cat# AF232 anti-FGF2 neutralizing antibody,R&D System,Cat# AF-233-NA anti-FGF5 neutralizing antibody,R&D System,Cat#

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FGF acidic/FGF1 Antibody

FGF acidic/FGF1 Antibody

FGF acidic/FGF1 Antibody

FGF acidic/FGF1 Antibody

FGF acidic/FGF1 Antibody

FGF acidic/FGF1 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (12)

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FGF acidic/FGF1 Antibody from R&D Systems, a Bio-Techne Brand

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