Fig 2: Serum CHL1 levels in GIST (A) Serum CHL1 levels of patients with GIST and healthy controls. (B) Receiver operating characteristic (ROC) curves of serum CHL1 levels for detecting GIST.

Fig 3: CHL1 expression analysis in GIST.(A) Relative mRNA expression levels of pan CHL1, and isoforms 1 and 2 in primary GIST, (B) Western blot analyses of CHL1 protein expression in primary tumors and metastases.

Fig 4: Representative immunohistochemical staining of local CHL1 expressions in GIST.(A) No expression (B) Low expression (C) High expression.