BMPR-IA/ALK-3 Antibody AF346 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemBMPR-IA/ALK-3 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $489.00Supplier Page View Company Product Page
Catalog NumberAF346
NCBI Gene AliasesCD292, ACVRLK3, ALK-3, 10q23del, BMPR-1A, SKR5, ALK3
ApplicationsFlow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry,Functional Assay
ReactivityHuman,Mouse
IsotypeIgG
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
Conjugate/TagUnconjugated
HostGoat
Quantity100 ug (also 25 ug)
TargetBMPR-IA/ALK-3
NCBI Full Gene Namebone morphogenetic protein receptor type 1A
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant human BMPR-IA/AKL-3, Gln24-Arg152, Accession # P36894
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human BMPR-IA in direct ELISAs and Western blots.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Human myeloid differentiation by BMP4 signaling through the VDR pathway in acute myeloid leukemiaCell Death DiscoveryJuly 16, 2024Florence Zylbersztejn, Iryna Byelinska, Sandrine Jeanpierre, Léa Barral, Kevin Geistlich, Mario Flores-Violante, Thibault Voeltzel, Etienne Paubelle, Mael Heiblig, Vincent Alcazer, et al.rank test B CD34+ from healthy samples were also treated with or without BMPR1A blocking antibody (AF346 R&D System), and data are presented as violin plot of n = 5 independent experiments using CD34+ isolated

(2) Novel role of bone morphogenetic protein 9 in innate host responses to HCMV infectionEMBO ReportsMarch 11, 2024Markus Stempel, Oliver Maier, Baxolele Mhlekude, Hal Drakesmith, Melanie M Brinkmannclone 117702), anti-activin RIA/ALK2 (#MAB637, clone 71412) and goat polyclonal anti-BMPR-IA/ALK3 (#AF346) were purchased from Novus Biologicals. Mouse monoclonal anti-BMPR2 (#ab130206, clone 1F12) was purchased

(3) Anti-Müllerian hormone concentration regulates activin receptor-like kinase-2/3 expression levels with opposing effects on ovarian cancer cell survivalInternational journal of oncologyJuly 1, 2021Chauvin M, Garambois V, Choblet S, Colombo PE, Chentouf M, Gros L, De Brauwere DP, Duonor-Cerutti M, Dumas K, Robert B, et al.used as negative controls), the anti-AMHRII 12G4, and anti-ALK2 (cat. no. AF637), anti-ALK3 (cat. no. AF346) and anti-ALK6 (cat. no. MAB5051) (all from R&D Systems, Inc.) primary antibodies in the dark for 1

(4) Bioactive Lipid O-cyclic phytosphingosine-1-phosphate Promotes Differentiation of Human Embryonic Stem Cells into Cardiomyocytes via ALK3/BMPR SignalingInternational journal of molecular sciencesJune 29, 2021Jang JH, Kim MS, Antao AM, Jo WJ, Kim HJ, Kim SJ, Choi MJ, Ramakrishna S, Kim KS.(sc-6055),1:1000 RHOA,Abcam (ab187027),1:2000 ALK2,Santa Cruz (sc-374523),1:1000 ALK3,R&D Systems (AF346),1:200 p-Erk,Cell Signaling (#9101),1:1000 Erk,Cell Signaling (#9102),1:1000 Antibody information

(5) A new signaling cascade linking BMP4, BMPR1A, ΔNp73 and NANOG impacts on stem-like human cell properties and patient outcomeCell death & diseaseSeptember 27, 2018Voeltzel T, Flores-Violante M, Zylbersztejn F, Lefort S, Billandon M, Jeanpierre S, Joly S, Fossard G, Milenkov M, Mazurier F, et al.added in serum-free medium as indicated18,20. Normal goat IgG control (AB-108-C) and anti-hBMPR1A (AF346) (R&D Systems) were used at 4 µg/mL. Functional assays Colony-forming cell (CFC) and long-term culture-initiating

(6) Chronic myeloid leukaemia cells require the bone morphogenic protein pathway for cell cycle progression and self-renewalCell death & diseaseSeptember 11, 2018Toofan P, Busch C, Morrison H, O'Brien S, Jørgensen H, Copland M, Wheadon H.

(7) The BMP Pathway Participates in Human Naive CD4+ T Cell Activation and HomeostasisPloS oneJanuary 1, 2015Martínez VG, Sacedón R, Hidalgo L, Valencia J, Fernández-Sevilla LM, Hernández-López C, Vicente A, Varas A.

(8) Optimal effector functions in human natural killer cells rely upon autocrine bone morphogenetic protein signalingCancer researchSeptember 15, 2014Robson NC, Hidalgo L, Mc Alpine T, Wei H, Martínez VG, Entrena A, Melen GJ, MacDonald AS, Phythian-Adams A, Sacedón R, et al.

(9) Bone morphogenetic protein-9 activates Smad and ERK pathways and supports human osteoclast function and survival in vitroCellular signallingApril 1, 2013Fong D, Bisson M, Laberge G, McManus S, Grenier G, Faucheux N, Roux S.

(10) The transforming growth factor-beta type III receptor mediates distinct subcellular trafficking and downstream signaling of activin-like kinase (ALK)3 and ALK6 receptorsMolecular Biology of the CellOctober 15, 2009Nam Y. Lee, Kellye C. Kirkbride, Richard D. Sheu, Gerard C. BlobeLefkowitz (Duke University, Durham, NC). Recombinant BMP-2 (355-BM), along with T␤RIII (AF-242), ALK3 (AF346), and ALK6 (AF-505) goat antibodies were all purchased from R&D Systems (Minneapolis, MN). Fluorescently

(11) Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cellsCancer cellJanuary 1, 2008Lee J, Son MJ, Woolard K, Donin NM, Li A, Cheng CH, Kotliarova S, Kotliarov Y, Walling J, Ahn S, et al.

(12) Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transitionThe Journal of biological chemistryAugust 10, 2007Zeisberg M, Yang C, Martino M, Duncan MB, Rieder F, Tanjore H, Kalluri R.

(13) Bone morphogenetic protein-mediated modulation of lineage diversification during neural differentiation of embryonic stem cellsStem CellsApril 1, 2007Gossrau G, Thiele J, Konang R, Schmandt T, Brüstle O.

(14) Altered bone morphogenetic protein signalling in the Helicobacter pylori-infected stomachThe Journal of pathologyJune 1, 2006Bleuming SA, Kodach LL, Garcia Leon MJ, Richel DJ, Peppelenbosch MP, Reitsma PH, Hardwick JC, van den Brink GR.

(15) Developmental pattern of expression of BMP receptors and Smads and activation of Smad1 and Smad5 by BMP9 in mouse basal forebrainBrain researchMay 9, 2006Lopez-Coviella I, Mellott TM, Kovacheva VP, Berse B, Slack BE, Zemelko V, Schnitzler A, Blusztajn JK.

(16) BMP4 inhibits breast cancer metastasis by blocking myeloid-derived suppressor cell activityCancer researchJanuary 1, 0001"Cao Y, Slaney CY, Bidwell BN, Parker BS, Johnstone CN, Rautela J, Eckhardt BL, Anderson RL."

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BMPR-IA/ALK-3 Antibody

BMPR-IA/ALK-3 Antibody

BMPR-IA/ALK-3 Antibody

BMPR-IA/ALK-3 Antibody

BMPR-IA/ALK-3 Antibody

BMPR-IA/ALK-3 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (16)

Reviews

BMPR-IA/ALK-3 Antibody from R&D Systems, a Bio-Techne Brand

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