CD28 Antibody AF-342-PB from R&D Systems, a Bio-Techne Brand

Product Specs
ItemCD28 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $539.00Supplier Page View Company Product Page
Catalog NumberAF-342-PB
NCBI Gene AliasesTp44
ApplicationsELISA Development,Flow Cytometry,Immunohistochemistry,Agonist Activity,Immunocytochemistry,CyTOF-ready,Functional Assay,Cell Culture
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
TargetCD28
Conjugate/TagUnconjugated
HostGoat
Quantity200 ug (also 25 ug)
ReactivityHuman,Mouse
IsotypeIgG
NCBI Full Gene NameCD28 molecule
ClonalityPolyclonal
ImmunogenS. frugiperda insect ovarian cell line Sf 21-derived recombinant human CD28, Asn19-Pro152, Accession # P10747
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human CD28 in direct ELISAs and Western blots.

Sizes Available: 200 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) The homodimer interfaces of costimulatory receptors B7 and CD28 control their engagement and pro-inflammatory signalingJournal of biomedical scienceJune 28, 2023Popugailo A, Rotfogel Z, Levy M, Turgeman O, Hillman D, Levy R, Arad G, Shpilka T, Kaempfer R.

(2) Mesangial Cells Exhibit Features of Antigen-Presenting Cells and Activate CD4+ T Cell ResponsesJournal of immunology researchJanuary 1, 2019Yu H, Cui S, Mei Y, Li Q, Wu L, Duan S, Cai G, Zhu H, Fu B, Zhang L, et al.

(3) Diversification of Bw4 Specificity and Recognition of a Nonclassical MHC Class I Molecule Implicated in Maternal-Fetal Tolerance by Killer Cell Ig-like Receptors of the Rhesus MacaqueJournal of immunology (Baltimore, Md. : 1950)November 1, 2018Banerjee P, Ries M, Janaka SK, Grandea AG 3rd, Wiseman R, O'Connor DH, Golos TG, Evans DT.

(4) Dysregulated CD46 shedding interferes with Th1-contraction in systemic lupus erythematosusEuropean journal of immunologyJuly 1, 2017Ellinghaus U, Cortini A, Pinder CL, Le Friec G, Kemper C, Vyse TJ.recombinant proteins, and inhibitors Cell stimulating antibodies to CD3 (clone OKT‐3), CD28 (clone AF‐342‐PB) and CD46 (clone 344519) were all purchased from R&D Systems. Neutralizing antibodies to IL‐4 (clone

(5) Phenotype, function, and differentiation potential of human monocyte subsetsPloS oneJanuary 1, 2017Boyette LB, Macedo C, Hadi K, Elinoff BD, Walters JT, Ramaswami B, Chalasani G, Taboas JM, Lakkis FG, Metes DM.

(6) Binding of superantigen toxins into the CD28 homodimer interface is essential for induction of cytokine genes that mediate lethal shockPLoS biologySeptember 1, 2011Arad G, Levy R, Nasie I, Hillman D, Rotfogel Z, Barash U, Supper E, Shpilka T, Minis A, Kaempfer R.mAb (clone 37710) and anti-human B7-2/CD86 mAb (clone 37301), goat IgG anti-human CD28 polyclonal Ab (AF-342-PB) and goat IgG anti-human B7-2/CD86 polyclonal Ab (AF-141-NF), from R&D Systems. Binding of αCD28 to

(7) Cloning and characterization of an adenoviral vector for highly efficient and doxycycline – suppressible expression of bioactive human single – chain interleukin 12 in colon cancerBMC BiotechnologyDecember 1, 2007Holger Wulff, Thorsten Krieger, Karen Krüger, Ingrid Stahmer, Friedrich Thaiss, Hansjörg Schäfer, Andreas BlockMinneapolis, MN) and separated MNC were then incubated in the presence of an anti-human CD28 antibody (#AF-342-PB, R&D Systems) at 0.5 µg/ml for three days. Prestimulated MNC were seeded into 96 well plates at 4 ×

(8) CD28-mediated regulation of multiple myeloma cell proliferation and survivalBloodJune 1, 2007Bahlis NJ, King AM, Kolonias D, Carlson LM, Liu HY, Hussein MA, Terebelo HR, Byrne GE Jr, Levine BL, Boise LH, et al.

(9) The soluble forms of CD28, CD86 and CTLA-4 constitute possible immunological markers in patients with abdominal aortic aneurysmJournal of internal medicineApril 1, 2007Sakthivel P, Shively V, Kakoulidou M, Pearce W, Lefvert AK.

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CD28 Antibody

CD28 Antibody

CD28 Antibody

CD28 Antibody

CD28 Antibody

CD28 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (9)

Reviews

CD28 Antibody from R&D Systems, a Bio-Techne Brand

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