TGF-alpha Antibody AF-239-NA from R&D Systems, a Bio-Techne Brand

Product Specs
ItemTGF-alpha Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $539.00Supplier Page View Company Product Page
Catalog NumberAF-239-NA
NCBI Gene AliasesTFGA
ApplicationsELISA Microarray Development,Immunodepletion,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Neutralization,ELISA Capture (Matched Antibody Pair),Immunocytochemistry,ELISA Capture
Conjugate/TagUnconjugated
HostGoat
ReactivityHuman,Mouse
IsotypeIgG
Quantity100 ug (also 25 ug)
TargetTGF-alpha
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
NCBI Full Gene Nametransforming growth factor alpha
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant human TGF-alpha, Val40-Ala89, Accession # P01135
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human TGF-alpha in ELISAs and Western blots. In sandwich immunoassays, less than 0.05% cross-reactivity with recombinant human (rh) TGF¿ß1, rhAmphiregulin, rhBetacellulin, rhEGF, rhHRG-alpha, and rhSMDF is observed.

Sizes Available: 100 ug (also 25 ug)

Add to Compare List

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Mesenchymal Transglutaminase 2 Activates Epithelial ADAM17: Link to G-Protein-Coupled Receptor 56 (ADGRG1) SignallingInternational journal of molecular sciencesFebruary 16, 2024Bauer L, Edwards J, Heil A, Dewitt S, Biebermann H, Aeschlimann D, Knäuper V.confirmed mutations. R&D systems supplied N-GPR56 (AF4634), EGF (MAB236), HB-EGF (MAB2591), TGF-α (AF-239-NA) antibodies, Invitrogen (now Thermo Fisher Scientific, Waltham, MA, USA) anti-V5 (R-96025), Alexa dye,

(2) Locally advanced rectal cancer transcriptomic-based secretome analysis reveals novel biomarkers useful to identify patients according to neoadjuvant chemoradiotherapy responseScientific reportsJune 18, 2019Canto LMD, Cury SS, Barros-Filho MC, Kupper BEC, Begnami MDFS, Scapulatempo-Neto C, Carvalho RF, Marchi FA, Olsen DA, Madsen JS, et al.R&D Systems, Minneapolis, MN, USA), betacellulin (cat.no. AF-261-NA, R&D Systems) and TGF-α (cat.no. AF-239-NA, R&D Systems). The concentration of the detection antibodies was 0.4 µg/mL amphiregulin (cat.no. BAF262,

(3) Temporal expression of growth factors triggered by epiregulin regulates inflammation developmentJournal of immunology (Baltimore, Md. : 1950)February 1, 2015Harada M, Kamimura D, Arima Y, Kohsaka H, Nakatsuji Y, Nishida M, Atsumi T, Meng J, Bando H, Singh R, et al.

(4) Amphiregulin carboxy-terminal domain is required for autocrine keratinocyte growthThe Journal of investigative dermatologyAugust 1, 2010Stoll SW, Johnson JL, Li Y, Rittié L, Elder JT.

(5) Cytokines and growth factors expressed by human cutaneous melanomaCancersMay 7, 2010Elias EG, Hasskamp JH, Sharma BK.UK" FGF-basic,Polyclonal,AB-233-NA,"R&D Systems, Minneapolis, MN" EGF,Monoclonal,E-2520,"Sigma, St Louis, MO" TGF-alpha,Polyclonal,AF-239-NA,"R&D Systems, Minneapolis, MN" Details of the antibodies used for IHC of cytokines and growth factors.

(6) Differential contribution to neuroendocrine tumorigenesis of parallel egfr signaling in cancer cells and pericytesGenes & cancerFebruary 1, 2010Nolan-Stevaux O, Truitt MC, Pahler JC, Olson P, Guinto C, Lee DC, Hanahan D.Western Blot Analysis The following antibodies were used: goat anti-TGF-α (0.2 μg/mL [R&D Systems, Minneapolis, MN, #AF-239-NA]), goat anti-HB-EGF (0.2 μg/mL [R&D Systems #AF-259-NA]), rabbit anti-SV40 large T antigen (1:10,000),55

(7) The luteinizing hormone receptor-activated extracellularly regulated kinase-1/2 cascade stimulates epiregulin release from granulosa cellsEndocrinologyNovember 1, 2008Andric N, Ascoli M.

(8) Association of tetraspanin CD9 with transmembrane TGF{alpha} confers alterations in cell-surface presentation of TGF{alpha} and cytoskeletal organizationJournal of cell scienceJuly 1, 2008Imhof I, Gasper WJ, Derynck R.

(9) Development and validation of sandwich ELISA microarrays with minimal assay interferenceJournal of proteome researchJune 1, 2008Gonzalez RM, Seurynck-Servoss SL, Crowley SA, Brown M, Omenn GS, Hayes DF, Zangar RC.

(10) Expression and role of EGFR ligands induced in airway cells by PM2.5 and its componentsThe European respiratory journalDecember 1, 2007Rumelhard M, Ramgolam K, Hamel R, Marano F, Baeza-Squiban A.

(11) EGFR signaling is required for TGF-beta 1 mediated COX-2 induction in human bronchial epithelial cellsAmerican journal of respiratory cell and molecular biologyNovember 1, 2007Liu M, Yang SC, Sharma S, Luo J, Cui X, Peebles KA, Huang M, Sato M, Ramirez RD, Shay JW, et al.prevention. MATERIALS AND METHODS 579 amphiregulin (catalog number: AF262), TGF-a (catalog number: AF239-NA), EGF (catalog number: AF236), and HB-EGF (catalog number: AF-259-NA) were purchased from R&D Systems.

(12) Epidermal growth factor-like growth factors prevent apoptosis of alcohol-exposed human placental cytotrophoblast cellsBiology of reproductionJuly 1, 2007Wolff GS, Chiang PJ, Smith SM, Romero R, Armant DR.

(13) Transforming growth factor-alpha: a major human serum factor that promotes human keratinocyte migrationThe Journal of investigative dermatologySeptember 1, 2006Li Y, Fan J, Chen M, Li W, Woodley DT.

(14) The response of human epithelial cells to TNF involves an inducible autocrine cascadeCellMarch 24, 2006Janes KA, Gaudet S, Albeck JG, Nielsen UB, Lauffenburger DA, Sorger PK.

(15) Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutantsPLoS medicineNovember 1, 2005Greulich H, Chen TH, Feng W, Jänne PA, Alvarez JV, Zappaterra M, Bulmer SE, Frank DA, Hahn WC, Sellers WR, et al.anti-EGF (R&D Systems, Minneapolis, Minnesota, United States; #MAB636), 12 μg/ml anti-TGFα (R&D Systems; #AF-239-NA), and 12 μg/ml anti-EGFR (Upstate, Waltham, Massachusetts, United States; #05–101). Gefitinib and erlotinib

(16) Autocrine extracellular signal-regulated kinase (ERK) activation in normal human keratinocytes: metalloproteinase-mediated release of amphiregulin triggers signaling from ErbB1 to ERKMolecular biology of the cellSeptember 1, 2004Kansra S, Stoll SW, Johnson JL, Elder JT.

(17) Mek1 alters epidermal growth and differentiationCancer researchSeptember 1, 2004Scholl FA, Dumesic PA, Khavari PA.

(18) Heparin-binding EGF-like growth factor regulates human extravillous cytotrophoblast development during conversion to the invasive phenotypeDevelopmental biologyFebruary 15, 2004Leach RE, Kilburn B, Wang J, Liu Z, Romero R, Armant DR.

Be the First to Write a Review!

TGF-alpha Antibody

TGF-alpha Antibody

TGF-alpha Antibody

TGF-alpha Antibody

TGF-alpha Antibody

TGF-alpha Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (18)

Reviews

TGF-alpha Antibody from R&D Systems, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map